AIDS patient care and STDs最新文献_第5页

Prevalence, Monitoring, Treatment, and Control of Type 2 Diabetes by Race and Sexual Orientation Among Males with HIV. 按种族和性取向分列的男性 HIV 感染者中 2 型糖尿病的患病率、监测、治疗和控制情况。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-12-01 Epub Date: 2024-10-28 DOI: 10.1089/apc.2024.0193

Jiali Guo, Samuel C O Opara, Sophia A Hussen, Jithin Sam Varghese

引用次数: 0

Impact of Expanded HIV Testing and Rapid Antiretroviral Therapy Initiation in Southwest China: An Interrupted Time-Series Analysis. 中国西南地区扩大 HIV 检测和快速抗逆转录病毒疗法的影响：中断时间序列分析

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-12-01 Epub Date: 2024-11-15 DOI: 10.1089/apc.2024.0205

Zhiwen Pi, Ticheng Xiao, Ningjun Ren, Biao Yu, Jinyu Chen, Jingbo Zhang, Lingxi He, Yingming Wang, Huachun Zou, Run Chen, Xiaoxue Chen, Fuli Huang, Yanhua Chen, Hang Chen, Ailing Li, Song Fan

{"title":"Impact of Expanded HIV Testing and Rapid Antiretroviral Therapy Initiation in Southwest China: An Interrupted Time-Series Analysis.","authors":"Zhiwen Pi, Ticheng Xiao, Ningjun Ren, Biao Yu, Jinyu Chen, Jingbo Zhang, Lingxi He, Yingming Wang, Huachun Zou, Run Chen, Xiaoxue Chen, Fuli Huang, Yanhua Chen, Hang Chen, Ailing Li, Song Fan","doi":"10.1089/apc.2024.0205","DOIUrl":"10.1089/apc.2024.0205","url":null,"abstract":"This study evaluates the impact of an expanded HIV testing initiative, launched in June 2018 in Luzhou, Sichuan, China, on antiretroviral therapy (ART) initiation rates among people living with HIV (PLWH). Using an uncontrolled interrupted time-series design, we analyzed data from 11,040 PLWH between June 2016 and December 2022, extracted from 108 health facilities via the Center for Disease Control and Prevention's ART database. The primary outcome measures were ART initiation rates within 7 and 30 days of HIV diagnosis. Results showed a significant improvement in the 30-day ART initiation rate following expanded testing, increasing from 46.1% to 90.9% by the study's end. The 7-day initiation rate also improved but remained below 30%. The study found that expanded testing enhanced the role of primary health care institutions in ART initiation. However, the COVID-19 pandemic, beginning January 2020, negatively impacted ART initiation rates, with a slight effect on 30-day rates but a persistent negative impact on 7-day rates. Despite these challenges and an increased HIV burden, Luzhou's ART initiation rates surpassed the national average. This study emphasizes the effectiveness of expanded HIV testing in ensuring timely ART access, crucial for HIV epidemic control, and improved patient outcomes. It also reveals challenges in maintaining HIV services during public health crises, offering insights into health care system resilience. Future research should focus on evaluating long-term treatment outcomes and strategies to support ending the AIDS epidemic.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"551-558"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rejection of Federal Guidance by Southern US States and Projected Consequences for Ending the HIV Epidemic. 美国南部各州拒绝接受联邦指导意见以及对遏制艾滋病毒流行的预期后果》（Rejection of Federal Guidance by Southern US States and Projected Consequences for Ending HIV Epidemic）。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-12-01 Epub Date: 2024-11-21 DOI: 10.1089/apc.2024.0182

Siena Senn, Nathan D Roberson, Lauren Brunet, Elise Lankiewicz, Jennifer Sherwood, Brian Honermann, Gregorio Millett

{"title":"Rejection of Federal Guidance by Southern US States and Projected Consequences for Ending the HIV Epidemic.","authors":"Siena Senn, Nathan D Roberson, Lauren Brunet, Elise Lankiewicz, Jennifer Sherwood, Brian Honermann, Gregorio Millett","doi":"10.1089/apc.2024.0182","DOIUrl":"10.1089/apc.2024.0182","url":null,"abstract":"Evidence-based HIV programming focused on populations at risk of HIV is critical for sustainable disease prevention. In response to the Tennessee Department of Health decision to reject federal HIV guidance, the present study examines the potential impact of Southern US states adopting policies that direct HIV prevention and testing efforts away from populations \"disproportionately affected\" (DA) by HIV toward populations \"non-disproportionately affected\" (NDA). Descriptive and projection analyses with publicly available data explored the influence of policies emphasizing NDA populations on HIV cases. Across the Southern US, DA populations (cisgender women, men who have sex with men, transgender persons, and people who inject drugs) represent the absolute majority (90%) of diagnosed HIV cases, whereas NDA populations (pregnant women, infants, first responders, and human trafficking victims) represent only a small proportion (2%) of diagnosed HIV cases. Estimated projections show avoidable HIV cases among DA populations in the Southern US alone could aggregate to over 32,000 by 2030 if prevention efforts exclusively concentrate on NDA populations, which approximates the current national annual incidence of 36,000 HIV cases. Prevention efforts aimed at DA populations compared with NDA populations could reduce new infections across the Southern US by 47% versus 1%, respectively, by 2030. Policies disregarding epidemiological data may hinder efforts to end the HIV epidemic, both regionally and nationally.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"559-565"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burden of Kidney Disease in an Aging Population Living with HIV in the United States. 美国感染艾滋病毒的老龄人口的肾病负担。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-12-01 Epub Date: 2024-11-11 DOI: 10.1089/apc.2024.0202

Franck Mbuntcha Bogni, Shem Kentish, Bao Ngan Tran, Ermais S Araia, Thomas Krahn, George Bayliss, Timothy P Flanigan, Fizza S Gillani

{"title":"Burden of Kidney Disease in an Aging Population Living with HIV in the United States.","authors":"Franck Mbuntcha Bogni, Shem Kentish, Bao Ngan Tran, Ermais S Araia, Thomas Krahn, George Bayliss, Timothy P Flanigan, Fizza S Gillani","doi":"10.1089/apc.2024.0202","DOIUrl":"10.1089/apc.2024.0202","url":null,"abstract":"Antiretroviral therapy (ART) has significantly improved mortality rates for individuals living with HIV, but kidney disease remains prevalent, especially among older adults. Our study analyzed the burden of kidney disease in individuals aged 65 and older at The Miriam Hospital Immunology Center in Rhode Island. We calculated estimated glomerular filtration rates using the last creatinine values from 2019 and identified chronic kidney disease (CKD) stages. Results showed a 19% prevalence of moderate or severe CKD among adults living with HIV, rising to 39% for those aged 75 and older. Particularly striking was the increased prevalence among African American adults aged 65+, at 30.4%, rising to 50% for those over 75. In comparison, the National Institute of Diabetes and Digestive and Kidney Diseases reports that CKD stage 3 affects 20.1% of adults aged 65+, compared with just 1.2% in those younger than 65. Gender and racial disparities are evident; CKD stage 3 is more prevalent in females (5.8%) than males (4.4%). Our findings indicate that 32% of HIV-positive females have moderate-to-severe kidney disease, compared with 14% of males. Importantly, we did not account for hypertension, diabetes, and hepatitis C virus infection, which may influence renal outcomes. Our study shows that ART has reduced mortality, as more people with HIV now live longer, while also revealing the disproportionate burden of kidney disease among older adults and racial minorities, as well as a concerning trend among women; therefore, emphasizing the need for targeted health care strategies for high-risk groups.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"543-550"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying Motivators, Facilitators, and Barriers to Engagement and Retention in Anal Cancer Screening Among Men and Women with HIV in One Ryan White HIV/AIDS Clinic. 确定瑞安-怀特艾滋病毒/艾滋病诊所中感染艾滋病毒的男性和女性参与和坚持肛门癌筛查的动机、促进因素和障碍。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-11-01 Epub Date: 2024-10-14 DOI: 10.1089/apc.2024.0171

Maria C Geba, Divya Kalluri, Emma M Mitchell, Tabor Flickinger, Ben Cardenas, Rebecca Dillingham, Tania A Thomas

{"title":"Identifying Motivators, Facilitators, and Barriers to Engagement and Retention in Anal Cancer Screening Among Men and Women with HIV in One Ryan White HIV/AIDS Clinic.","authors":"Maria C Geba, Divya Kalluri, Emma M Mitchell, Tabor Flickinger, Ben Cardenas, Rebecca Dillingham, Tania A Thomas","doi":"10.1089/apc.2024.0171","DOIUrl":"10.1089/apc.2024.0171","url":null,"abstract":"Anal squamous cell carcinoma disproportionally affects people with HIV (PWH); however, engagement in anal cancer screening is low in many settings. This study was conducted to assess knowledge and perceptions of anal cancer screening to identify factors in the engagement and retention in prevention services among PWH. Semistructured interviews were conducted among adult PWH eligible for anal cancer screening in our Ryan White HIV/AIDS Program clinic. Descriptive statistics were tabulated; thematic analyses were performed to identify emerging motivators, facilitators, and barriers. Among 26 PWH, 9 had not been screened, 8 had undergone Papanicolaou (Pap) testing alone, and 9 had undergone anoscopy. The median age of the cohort was 55.2 years; 54% identified as men who have sex with men, and 54% identified as Black. In the unscreened cohort, participants were motivated by investing in their health and positive attitudes toward cancer prevention however were deterred by a lack of referral and low awareness about screening. Among those who had Pap testing, trust in healthcare providers and abnormal testing results were motivators to engagement, whereas lack of perceived risk of anal cancer and worry about pain of an anoscopy were prominent barriers. Among those who had anoscopy, perceived risk, positive experience with the procedure, and use of anxiolytics prior to anoscopy were motivators, whereas anxiety around a new cancer diagnosis and negative experience with anoscopy were barriers. Clinics seeking to build or strengthen their anal cancer screening programs can address the barriers described in this study to promote access to anal cancer screening among PWH.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"530-538"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"AIDS at a Crossroads:" Highlights from the 2024 UNAIDS Report. "艾滋病处于十字路口："联合国艾滋病规划署 2024 年报告要点。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-11-01 Epub Date: 2024-08-21 DOI: 10.1089/apc.2024.0172

Jeffrey Laurence

引用次数: 0

A Pilot Randomized Control Trial of the Motivational Interviewing to Increase PrEP Uptake Intervention Among Black Women in the United States. 在美国黑人妇女中开展动机访谈以提高 PrEP 使用率干预的试点随机对照试验。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-11-01 Epub Date: 2024-10-17 DOI: 10.1089/apc.2024.0189

Sannisha K Dale, Victoria Petrulla, Ian A Wright

{"title":"A Pilot Randomized Control Trial of the Motivational Interviewing to Increase PrEP Uptake Intervention Among Black Women in the United States.","authors":"Sannisha K Dale, Victoria Petrulla, Ian A Wright","doi":"10.1089/apc.2024.0189","DOIUrl":"10.1089/apc.2024.0189","url":null,"abstract":"Despite the disproportional impact of HIV, Black individuals are benefiting the least from pre-exposure prophylaxis (PrEP). Motivational interviewing (MI) for PrEP uptake (MI-PrEP) is a two-session culturally tailored intervention incorporating MI strategies to improve PrEP motivation and uptake among cisgender Black women. A pilot randomized control trial was conducted in the Southeastern United States, and 41 women were randomized to MI-PrEP (session 1 with PrEP psychoeducation and MI and session 2 with MI and light case management) or enhanced treatment as usual (ETAU; two sessions of PrEP psychoeducation [videos explaining PrEP]). Women completed one follow-up assessment (1 month after visit 2). Measures captured primary (motivation [via contemplation and readiness ruler] and PrEP uptake via medical records) and secondary outcomes (e.g., PrEP knowledge, barriers to PrEP, and speaking to a provider about PrEP). Difference-in-differences analyses comparing MI-PrEP with ETAU as well as t-tests for within-group changes over time were conducted. Women who completed MI-PrEP (90.5% retained) compared with ETAU (100% retained) had a significantly higher likelihood of speaking to a provider about PrEP (OR = 4.42e7, CI [8.55e6, 2.29e8], DiD = 17.60, se = 0.84, p < 0.001). Within the MI-PrEP group, women had significant increases in PrEP prescription, knowledge, and motivation/contemplation, and significant decreases in financial resources as a PrEP barrier and medical mistrust (MMT). ETAU had within-group increases in PrEP prescription and speaking to a provider, no changes in motivation and MMT, and increases in specific barriers to care (e.g., transportation). MI-PrEP shows promise, and a large-scale study may be beneficial to further assess efficacy and examine implementation.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"517-529"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre-Exposure Prophylaxis for the Prevention of HIV-1: An Assessment of Oral Pre-Exposure Prophylaxis Usage Patterns, First Evidence of HIV-1, and HIV-1 Risk Factors in the United States. 预防 HIV-1 的暴露前预防疗法：美国口服暴露前预防疗法使用模式、HIV-1 初诊证据和 HIV-1 风险因素评估》（Pre-Exposure Prophylaxis for the Prevention of HIV-1）。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-11-01 Epub Date: 2024-11-07 DOI: 10.1089/apc.2024.0158

Alan Oglesby, Guillaume Germain, Aimee A Metzner, François Laliberté, Sean D MacKnight, Annalise Hilts, Heidi Swygard, Mei S Duh

{"title":"Pre-Exposure Prophylaxis for the Prevention of HIV-1: An Assessment of Oral Pre-Exposure Prophylaxis Usage Patterns, First Evidence of HIV-1, and HIV-1 Risk Factors in the United States.","authors":"Alan Oglesby, Guillaume Germain, Aimee A Metzner, François Laliberté, Sean D MacKnight, Annalise Hilts, Heidi Swygard, Mei S Duh","doi":"10.1089/apc.2024.0158","DOIUrl":"10.1089/apc.2024.0158","url":null,"abstract":"In clinical trials, once-daily oral tenofovir-based pre-exposure prophylaxis (PrEP) significantly reduced HIV-1 acquisition risk; however, this was highly dependent on medication adherence and persistence. We report clinical characteristics, PrEP usage patterns, first evidence of HIV-1, and associated risk factors among adults with commercial insurance using oral PrEP in the United States using health plan claims from the IQVIA PharMetrics® Plus database between January 1, 2015, and March 31, 2020, from individuals who newly initiated emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) or FTC/tenofovir alafenamide (TAF) for daily PrEP. Overall, 25,419 individuals were included (FTC/TDF, n = 24,232; FTC/TAF, n = 1187), with generally similar characteristics reported during the 6-month baseline period across cohorts. Mean follow-up length was 504 and 77 days for FTC/TDF and FTC/TAF, respectively, corresponding with the 2019 approval of FTC/TAF for PrEP. Similarly, mean PrEP use duration was 354 and 68 days for FTC/TDF and FTC/TAF, respectively. PrEP breaks (>90-day gap) were observed in 11.1% of individuals using FTC/TDF, with a mean break duration of 249 days; 20.0% of individuals using FTC/TDF and 7.3% using FTC/TAF had ≥1 sexually transmitted infection diagnosis during follow-up. From 6 to 12 months of follow-up, mean FTC/TDF proportion of days covered (PDC; 0.74 vs. 0.67) and persistence (70.2% vs. 57.4%) decreased; real-world PDC and persistence were lower than reported in globally conducted clinical trials. First evidence of HIV-1 was infrequent among individuals using FTC/TDF (0.6%), though 60.3% had PrEP on hand when HIV-1 definition was met; high-risk sexual behavior, syphilis, and gonorrhea were the most important risk factors.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":" ","pages":"495-506"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, Attitudes, and Perspectives of Women Who Have Migrated from Sub-Saharan Africa to France Toward HIV Pre-Exposure Prophylaxis in a Family Planning Center. 从撒哈拉以南非洲移居法国的妇女对计划生育中心艾滋病暴露前预防的认识、态度和观点。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-11-01 DOI: 10.1089/apc.2024.0190

Geoffroy Liegeon, Samantha A Devlin, Victoria Manda, Julie Castaneda, Catherine Marsh, Jessica P Ridgway, Amy K Johnson

{"title":"Knowledge, Attitudes, and Perspectives of Women Who Have Migrated from Sub-Saharan Africa to France Toward HIV Pre-Exposure Prophylaxis in a Family Planning Center.","authors":"Geoffroy Liegeon, Samantha A Devlin, Victoria Manda, Julie Castaneda, Catherine Marsh, Jessica P Ridgway, Amy K Johnson","doi":"10.1089/apc.2024.0190","DOIUrl":"https://doi.org/10.1089/apc.2024.0190","url":null,"abstract":"Women who have migrated from sub-Saharan Africa (SSA) are underrepresented among HIV pre-exposure prophylaxis (PrEP) users in France (∼2%), yet they account for around 20% of new HIV infections annually. We conducted focus groups to explore the knowledge, attitudes, and perspectives of these women toward PrEP in a French family planning center (FPC). Focus groups occurred from November 2023 to February 2024 within the Lariboisière Hospital FPC in Paris. The social ecological model informed the discussion guide, which explored women's PrEP experiences and determinants for uptake on various levels. Five focus groups were conducted (N = 19). The median age of participants was 29 [interquartile range (IQR) 28-37]. Eight African countries were represented. The average time in France since migration was 3 (IQR 1-6) years. The majority of women had never heard of PrEP but expressed strong interest in learning more about it. Women underscored the difficulty of negotiating HIV prevention tools with their partners, risks from transactional sex, and barriers to PrEP use such as adherence challenges to daily pills and misconceptions about HIV transmission. There was strong interest in long-acting injectable PrEP. Women reported high trust in FPC providers and viewed the FPC as an ideal location to access PrEP. Conspiracy theories, cultural beliefs, and anticipated stigma were also identified as barriers to PrEP uptake. Most women advocated for disseminating PrEP information to their peers using diverse community outreach strategies. Despite a strong interest, increasing PrEP uptake in women from SSA will remain challenging without multi-faceted and adapted implementation strategies.","PeriodicalId":7476,"journal":{"name":"AIDS patient care and STDs","volume":"38 11","pages":"507-516"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated with HIV Viral Suppression in People Followed in an Outpatient Clinic in Angola During and After the COVID-19 Pandemic. 在 COVID-19 大流行期间和之后，安哥拉一家门诊诊所随访的艾滋病毒病毒抑制者的相关因素。

IF 3.4 2区医学

AIDS patient care and STDs Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.1089/apc.2024.0175

Andrea Calcagno, Costanza Pizzi, Barbara Pocongo, Niccolò Ronzoni, Francesca Alladio, Ngiambudulu M Francisco, Alberto Kalume, Giovanni Di Perri, Federico Gobbi

引用次数: 0