Research integrity and peer review最新文献

{"title":"Critical review of the TransCelerate Template for clinical study reports (CSRs) and publication of Version 2 of the CORE Reference (<i>C</i>larity and <i>O</i>penness in <i>R</i>eporting: <i>E</i>3-based) Terminology Table.","authors":"Samina Hamilton,&nbsp;Aaron B Bernstein,&nbsp;Graham Blakey,&nbsp;Vivien Fagan,&nbsp;Tracy Farrow,&nbsp;Debbie Jordan,&nbsp;Walther Seiler,&nbsp;Art Gertel","doi":"10.1186/s41073-019-0075-5","DOIUrl":"https://doi.org/10.1186/s41073-019-0075-5","url":null,"abstract":"<p><strong>Background: </strong>CORE (<i>C</i>larity and <i>O</i>penness in <i>R</i>eporting: <i>E</i>3-based) Reference (released May 2016 by the European Medical Writers Association [EMWA] and the American Medical Writers Association [AMWA]) is a complete and authoritative open-access user's guide to support the authoring of clinical study reports (CSRs) for current industry-standard-design interventional studies. CORE Reference is a content guidance resource and is not a CSR Template.TransCelerate Biopharma Inc., an alliance of biopharmaceutical companies, released a CSR Template in November 2018 and recognised CORE Reference as one of two principal sources used in its development.</p><p><strong>Methods: </strong>The regulatory medical writing and statistical professionals who developed CORE Reference conducted a critical review of the TransCelerate CSR Template. We summarise our major findings and recommendations in this communication. We also re-examined and edited the Version 1 CORE Reference Terminology Table that we first published in 2016, and we present this as Version 2 in this communication.</p><p><strong>Results: </strong>Our major critical review findings indicate that opportunities remain to refine the CSR Template structure and instructional text, enhance content clarity, add web links to referenced guidance documents, improve transparency to support the broad readership of CSRs, and develop supporting resources.The CORE Reference 'Terminology Table' Version 2 includes estimand as a defined term and an adaptation of the original 'worked study example' to incorporate the recently evolved concept of 'estimands'.</p><p><strong>Conclusions: </strong>As TransCelerate's CSR Template represents an important milestone in authoring CSRs, we offer CSR authors advice and recommendations on its use, similarities, and differences with CORE Reference and advise them to consider shared interpretations between the two.</p><p><strong>Registration: </strong>CORE Reference is registered with the EQUATOR Network. The TransCelerate CSR Template is not registered with any external organisation to the knowledge of the authors of this paper.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2019-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0075-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41222962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publication and non-publication of clinical trials in PTSD: an overview.","authors":"Sharain Suliman, Leigh van den Heuvel, Alexandra Suryapranata, Jonathan I Bisson, Soraya Seedat","doi":"10.1186/s41073-019-0074-6","DOIUrl":"10.1186/s41073-019-0074-6","url":null,"abstract":"<p><strong>Background: </strong>Although a large number of clinical trials on interventions demonstrating efficacy (or lack thereof) are conducted annually, much of this evidence is not accessible to scientists and clinicians.</p><p><strong>Objectives: </strong>We aimed to determine the publication rate of posttraumatic stress disorder (PTSD) trials that have been registered in clinical trial registries, and the factors associated with publication.</p><p><strong>Methods: </strong>Trials, completed on January 15, 2015, were identified via the US National Institutes of Health clinical trials registry, the European Union Clinical Trials Register and the WHO International Clinical Trials Registry Platform. A systematic search for publications (published by the end of March 2018) related to each of the registered trials were then performed.</p><p><strong>Results: </strong>Four hundred and thirty-eight of 1982 potentially eligible trials were included. Only 34% of interventional trials were registered prior to initiation, 9% were registered within 2 months of starting and 20% after trial completion. Of the 438 included trials, 72% had generated peer-reviewed publications, while an additional 7% had disseminated results in some other form (such as on the trial database), 26 months after trial completion. Randomisation of a trial was the only factor individually associated with publication, in logistic regression analysis (<i>p</i> < 0.001). Intervention type, university as sponsor and study registration prior to completion were factors that influenced the time to publication, using Cox regression (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>This study underscores the importance of timely and accurate publication and dissemination of trial results, in order to avoid the potential waste of resources and to ensure research integrity and patient safety. We suggest that authors and journal editors adhere to conditions set out by the International Committee of Medical Journal Editors and that more diligent data sharing is encouraged through prospective trial registration and trial reporting websites.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"15"},"PeriodicalIF":7.2,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41222963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: ranking major and minor research misbehaviors: results from a survey among participants of four World Conferences on Research Integrity.","authors":"Lex M Bouter,&nbsp;Joeri Tijdink,&nbsp;Nils Axelsen,&nbsp;Brian C Martinson,&nbsp;Gerben Ter Riet","doi":"10.1186/s41073-019-0072-8","DOIUrl":"https://doi.org/10.1186/s41073-019-0072-8","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1186/s41073-016-0024-5.].</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0072-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37410705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus).","authors":"Kaitlyn Hair,&nbsp;Malcolm R Macleod,&nbsp;Emily S Sena","doi":"10.1186/s41073-019-0069-3","DOIUrl":"10.1186/s41073-019-0069-3","url":null,"abstract":"<p><strong>Background: </strong>The ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.</p><p><strong>Methods: </strong>In a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March-June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.</p><p><strong>Results: </strong>We randomised 1689 manuscripts (control: <i>n</i> = 844, intervention: <i>n</i> = 845), of which 1269 were sent for peer review and 762 (control: <i>n</i> = 340; intervention: <i>n</i> = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (<i>X</i> ² = 34.0, df = 1, <i>p</i> = 2.1 × 10^-7) in the control and intervention groups, respectively.</p><p><strong>Conclusions: </strong>These results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0069-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37339641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Good Practice for Conference Abstracts and Presentations: GPCAP.","authors":"Cate Foster,&nbsp;Elizabeth Wager,&nbsp;Jackie Marchington,&nbsp;Mina Patel,&nbsp;Steve Banner,&nbsp;Nina C Kennard,&nbsp;Antonia Panayi,&nbsp;Rianne Stacey","doi":"10.1186/s41073-019-0070-x","DOIUrl":"10.1186/s41073-019-0070-x","url":null,"abstract":"<p><p>Research that has been sponsored by pharmaceutical, medical device and biotechnology companies is often presented at scientific and medical conferences. However, practices vary between organizations and it can be difficult to follow both individual conference requirements and good publication practice guidelines. Until now, no specific guidelines or recommendations have been available to describe best practice for conference presentations. This document was developed by a working group of publication professionals and uploaded to PeerJ Preprints for consultation prior to publication; an additional 67 medical societies, medical conference sites and conference companies were also asked to comment. The resulting recommendations aim to complement current good publication practice and authorship guidelines, outline the general principles of best practice for conference presentations and provide recommendations around authorship, contributorship, financial transparency, prior publication and copyright, to conference organizers, authors and industry professionals. While the authors of this document recognize that individual conference guidelines should be respected, they urge organizers to consider authorship criteria and data transparency when designing submission sites and setting parameters around word/character count and content for abstracts. It is also important to recognize that conference presentations have different limitations to full journal publications, for example, in the case of limited audiences that necessitate refocused abstracts, or where lead authors do not speak the local language, and these have been acknowledged accordingly. The authors also recognize the need for further clarity regarding copyright of previously published abstracts and have made recommendations to assist with best practice. By following Good Practice for Conference Abstracts and Presentations: GPCAP recommendations, industry professionals, authors and conference organizers will improve consistency, transparency and integrity of publications submitted to conferences worldwide.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2019-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0070-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37315202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The advantages of peer review over arbitration for resolving authorship disputes.","authors":"Zubin Master,&nbsp;Evelyn Tenenbaum","doi":"10.1186/s41073-019-0071-9","DOIUrl":"https://doi.org/10.1186/s41073-019-0071-9","url":null,"abstract":"<p><p>A recent commentary argued for arbitration to resolve authorship disputes within academic research settings explaining that current mechanisms to resolve conflicts result in unclear outcomes and institutional power vested in senior investigators could compromise fairness. We argue here that arbitration is not a suitable means to resolve disputes among researchers in academia because it remains unclear who will assume the costs of arbitration, the rules of evidence do not apply to arbitration, and decisions are binding and very difficult to appeal. Instead of arbitration, we advocate for peer-based approaches involving a peer review committee and research ethics consultation to help resolve authorship disagreements. We describe the composition of an institutional peer review committee to address authorship disputes. Both of these mechanisms are found, or can be formed, within academic institutions and offer several advantages to researchers who are likely to shy away from legalistic processes and gravitate towards those handled by their peers. Peer-based approaches are cheaper than arbitration and the experts involved have knowledge about academic publishing and the culture of research in the specific field. Decisions by knowledgeable and neutral experts could reduce bias, have greater authority, and could be appealed. Not only can peer-based approaches be leveraged to resolve authorship disagreements, but they may also enhance collegiality and promote a healthy team environment.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0071-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37302995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring the data gap: inclusion of sex and gender reporting in diabetes research.","authors":"Suzanne Day,&nbsp;Wei Wu,&nbsp;Robin Mason,&nbsp;Paula A Rochon","doi":"10.1186/s41073-019-0068-4","DOIUrl":"https://doi.org/10.1186/s41073-019-0068-4","url":null,"abstract":"<p><strong>Background: </strong>Important sex and gender differences have been found in research on diabetes complications and treatment. Reporting on whether and how sex and gender impact research findings is crucial for developing tailored diabetes care strategies. To analyze the extent to which this information is available in current diabetes research, we examined original investigations on diabetes for the integration of sex and gender in study reporting.</p><p><strong>Methods: </strong>We examined original investigations on diabetes published between January 1 and December 31, 2015, in the top five general medicine journals and top five diabetes-specific journals (by 2015 impact factor). Data were extracted on sex and gender integration across seven article sections: title, abstract, introduction, methods, results, discussion, and limitations.</p><p><strong>Results: </strong>We identified 155 original investigations on diabetes, including 115 randomized controlled trials (RCTs) and 40 observational studies. Sex and gender were rarely incorporated in article titles, abstracts and introductions. Most methods sections did not describe plans for sex/gender analyses; 47 (30.3%) articles described plans to control for sex/gender in the analysis and 12 (7.7%) described plans to stratify results by sex/gender. While most articles (151, 97.4%) reported the sex/gender of study participants, only 10 (6.5%) of all articles reported all study outcomes separately by sex/gender. Discussion of sex-related issues was incorporated into 21 (13.5%) original investigations; however, just 1 (0.6%) discussed gender-related issues. Comparison by journal type (general medicine vs. diabetes specific) yielded only minor differences from the overall integration results. In contrast, RCTs performed more poorly on multiple sex/gender assessment metrics compared to observational studies.</p><p><strong>Conclusions: </strong>Sex and gender are poorly integrated in current diabetes original investigations, suggesting that substantial improvements in sex and gender data reporting are needed to inform the evidence to support sex- and gender-specific diabetes care.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2019-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0068-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37233205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Policy driven changes in animal research practices: mapping researchers' attitudes towards animal-free innovations using the Netherlands as an example.","authors":"S Bressers,&nbsp;H van den Elzen,&nbsp;C Gräwe,&nbsp;D van den Oetelaar,&nbsp;P H A Postma,&nbsp;S K Schoustra","doi":"10.1186/s41073-019-0067-5","DOIUrl":"https://doi.org/10.1186/s41073-019-0067-5","url":null,"abstract":"<p><strong>Background: </strong>Reducing the number of animals used in experiments has become a priority for the governments of many countries. For these reductions to occur, animal-free alternatives must be made more available and, crucially, must be embraced by researchers.</p><p><strong>Methods: </strong>We conducted an international online survey for academics in the field of animal science (<i>N</i> = 367) to explore researchers' attitudes towards the implementation of animal-free innovations. Through this survey, we address three key questions. The first question is whether scientists who use animals in their research consider governmental goals for animal-free innovations achievable and whether they would support such goals. Secondly, responders were asked to rank the importance of ten roadblocks that could hamper the implementation of animal-free innovations. Finally, responders were asked whether they would migrate (either themselves or their research) if increased animal research regulations in their country of residence restricted their research.</p><p><strong>Results: </strong>While nearly half (40%) of the responders support governmental goals, the majority (71%) of researchers did not consider such goals achievable in their field within the near future. In terms of roadblocks for implementation of animal-free methods, ~ 80% of the responders considered 'reliability' as important, making it the most highly ranked roadblock. However, all other roadblocks were reported by most responders as somewhat important, suggesting that they must also be considered when addressing animal-free innovations. Importantly, a majority reported that they would consider migration to another country in response to a restrictive animal research policy. Thus, governments must consider the risk of researchers migrating to other institutes, states or countries, leading to a 'brain-drain' if policies are too strict or suitable animal-free alternatives are not available.</p><p><strong>Conclusion: </strong>Our findings suggest that development and implementation of animal-free innovations are hampered by multiple factors. We outline three pillars concerning education, governmental influence and data sharing, the implementation of which may help to overcome these roadblocks to animal-free innovations.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0067-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37187339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personally perceived publication pressure: revising the Publication Pressure Questionnaire (PPQ) by using work stress models.","authors":"Tamarinde L Haven,&nbsp;Marije Esther Evalien de Goede,&nbsp;Joeri K Tijdink,&nbsp;Frans Jeroen Oort","doi":"10.1186/s41073-019-0066-6","DOIUrl":"https://doi.org/10.1186/s41073-019-0066-6","url":null,"abstract":"<p><strong>Background: </strong>The emphasis on impact factors and the quantity of publications intensifies competition between researchers. This competition was traditionally considered an incentive to produce high-quality work, but there are unwanted side-effects of this competition like publication pressure. To measure the effect of publication pressure on researchers, the Publication Pressure Questionnaire (PPQ) was developed. Upon using the PPQ, some issues came to light that motivated a revision.</p><p><strong>Method: </strong>We constructed two new subscales based on work stress models using the facet method. We administered the revised PPQ (PPQr) to a convenience sample together with the Maslach Burnout Inventory (MBI) and the Work Design Questionnaire (WDQ). To assess which items best measured publication pressure, we carried out a principal component analysis (PCA). Reliability was sufficient when Cronbach's alpha > 0.7. Finally, we administered the PPQr in a larger, independent sample of researchers to check the reliability of the revised version.</p><p><strong>Results: </strong>Three components were identified as 'stress', 'attitude', and 'resources'. We selected 3 × 6 = 18 items with high loadings in the three-component solution. Based on the convenience sample, Cronbach's alphas were 0.83 for stress, 0.80 for attitude, and 0.76 for resources. We checked the validity of the PPQr by inspecting the correlations with the MBI and the WDQ. Stress correlated 0.62 with MBI's emotional exhaustion. Resources correlated 0.50 with relevant WDQ subscales. To assess the internal structure of the PPQr in the independent reliability sample, we conducted the principal component analysis. The three-component solution explains 50% of the variance. Cronbach's alphas were 0.80, 0.78, and 0.75 for stress, attitude, and resources, respectively.</p><p><strong>Conclusion: </strong>We conclude that the PPQr is a valid and reliable instrument to measure publication pressure in academic researchers from all disciplinary fields. The PPQr strongly relates to burnout and could also be beneficial for policy makers and research institutions to assess the degree of publication pressure in their institute.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0066-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37347931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective citation in scientific literature on the human health effects of bisphenol A.","authors":"M J E Urlings,&nbsp;B Duyx,&nbsp;G M H Swaen,&nbsp;L M Bouter,&nbsp;M P Zeegers","doi":"10.1186/s41073-019-0065-7","DOIUrl":"https://doi.org/10.1186/s41073-019-0065-7","url":null,"abstract":"<p><strong>Introduction: </strong>Bisphenol A is highly debated and studied in relation to a variety of health outcomes. This large variation in the literature makes BPA a topic that is prone to selective use of literature, in order to underpin one's own findings and opinion. Over time, selective use of literature, by means of citations, can lead to a skewed knowledge development and a biased scientific consensus. In this study, we assess which factors drive citation and whether this results in the overrepresentation of harmful health effects of BPA.</p><p><strong>Methods: </strong>A citation network analysis was performed to test various determinants of citation. A systematic search identified all relevant publications on the human health effect of BPA. Data were extracted on potential determinants of selective citation, such as study outcome, study design, sample size, journal impact factor, authority of the author, self-citation, and funding source. We applied random effect logistic regression to assess whether these determinants influence the likelihood of citation.</p><p><strong>Results: </strong>One hundred sixty-nine publications on BPA were identified, with 12,432 potential citation pathways of which 808 citations occurred. The network consisted of 63 cross-sectional studies, 34 cohort studies, 29 case-control studies, 35 narrative reviews, and 8 systematic reviews. Positive studies have a 1.5 times greater chance of being cited compared to negative studies. Additionally, the authority of the author and self-citation are consistently found to be positively associated with the likelihood of being cited. Overall, the network seems to be highly influenced by two highly cited publications, whereas 60 out of 169 publications received no citations.</p><p><strong>Conclusion: </strong>In the literature on BPA, citation is mostly driven by positive study outcome and author-related factors, such as high authority within the network. Interpreting the impact of these factors and the big influence of a few highly cited publications, it can be questioned to which extent the knowledge development in human literature on BPA is actually evidence-based.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"4 ","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41073-019-0065-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37144238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}