Edwin Were, Jepchirchir Kiplagat, Eunice Kaguiri, Rose Ayikukwei, Violet Naanyu
{"title":"Institutional capacity to prevent and manage research misconduct: perspectives from Kenyan research regulators.","authors":"Edwin Were, Jepchirchir Kiplagat, Eunice Kaguiri, Rose Ayikukwei, Violet Naanyu","doi":"10.1186/s41073-023-00132-6","DOIUrl":"https://doi.org/10.1186/s41073-023-00132-6","url":null,"abstract":"<p><strong>Background: </strong>Research misconduct i.e. fabrication, falsification, and plagiarism is associated with individual, institutional, national, and global factors. Researchers' perceptions of weak or non-existent institutional guidelines on the prevention and management of research misconduct can encourage these practices. Few countries in Africa have clear guidance on research misconduct. In Kenya, the capacity to prevent or manage research misconduct in academic and research institutions has not been documented. The objective of this study was to explore the perceptions of Kenyan research regulators on the occurrence of and institutional capacity to prevent or manage research misconduct.</p><p><strong>Methods: </strong>Interviews with open-ended questions were conducted with 27 research regulators (chairs and secretaries of ethics committees, research directors of academic and research institutions, and national regulatory bodies). Among other questions, participants were asked: (1) How common is research misconduct in your view? (2) Does your institution have the capacity to prevent research misconduct? (3) Does your institution have the capacity to manage research misconduct? Their responses were audiotaped, transcribed, and coded using NVivo software. Deductive coding covered predefined themes including perceptions on occurrence, prevention detection, investigation, and management of research misconduct. Results are presented with illustrative quotes.</p><p><strong>Results: </strong>Respondents perceived research misconduct to be very common among students developing thesis reports. Their responses suggested there was no dedicated capacity to prevent or manage research misconduct at the institutional and national levels. There were no specific national guidelines on research misconduct. At the institutional level, the only capacity/efforts mentioned were directed at reducing, detecting, and managing student plagiarism. There was no direct mention of the capacity to manage fabrication and falsification or misconduct by faculty researchers. We recommend the development of Kenya code of conduct or research integrity guidelines that would cover misconduct.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10190722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Publisher Correction: Fighting reviewer fatigue or amplifying bias? Considerations and recommendations for use of ChatGPT and other large language models in scholarly peer review.","authors":"Mohammad Hosseini, Serge P J M Horbach","doi":"10.1186/s41073-023-00136-2","DOIUrl":"https://doi.org/10.1186/s41073-023-00136-2","url":null,"abstract":"","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10170319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben W Mol, Shimona Lai, Ayesha Rahim, Esmée M Bordewijk, Rui Wang, Rik van Eekelen, Lyle C Gurrin, Jim G Thornton, Madelon van Wely, Wentao Li
{"title":"Checklist to assess Trustworthiness in RAndomised Controlled Trials (TRACT checklist): concept proposal and pilot.","authors":"Ben W Mol, Shimona Lai, Ayesha Rahim, Esmée M Bordewijk, Rui Wang, Rik van Eekelen, Lyle C Gurrin, Jim G Thornton, Madelon van Wely, Wentao Li","doi":"10.1186/s41073-023-00130-8","DOIUrl":"10.1186/s41073-023-00130-8","url":null,"abstract":"<p><strong>Objectives: </strong>To propose a checklist that can be used to assess trustworthiness of randomized controlled trials (RCTs).</p><p><strong>Design: </strong>A screening tool was developed using the four-stage approach proposed by Moher et al. This included defining the scope, reviewing the evidence base, suggesting a list of items from piloting, and holding a consensus meeting. The initial checklist was set-up by a core group who had been involved in the assessment of problematic RCTs for several years. We piloted this in a consensus panel of several stakeholders, including health professionals, reviewers, journal editors, policymakers, researchers, and evidence-synthesis specialists. Each member was asked to score three articles with the checklist and the results were then discussed in consensus meetings.</p><p><strong>Outcome: </strong>The Trustworthiness in RAndomised Clinical Trials (TRACT) checklist includes 19 items organised into seven domains that are applicable to every RCT: 1) Governance, 2) Author Group, 3) Plausibility of Intervention Usage, 4) Timeframe, 5) Drop-out Rates, 6) Baseline Characteristics, and 7) Outcomes. Each item can be answered as either no concerns, some concerns/no information, or major concerns. If a study is assessed and found to have a majority of items rated at a major concern level, then editors, reviewers or evidence synthesizers should consider a more thorough investigation, including assessment of original individual participant data.</p><p><strong>Conclusions: </strong>The TRACT checklist is the first checklist developed specifically to detect trustworthiness issues in RCTs. It might help editors, publishers and researchers to screen for such issues in submitted or published RCTs in a transparent and replicable manner.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"6"},"PeriodicalIF":7.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10066264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Responsible research practices could be more strongly endorsed by Australian university codes of research conduct.","authors":"Yi Kai Ong, Kay L Double, Lisa Bero, Joanna Diong","doi":"10.1186/s41073-023-00129-1","DOIUrl":"https://doi.org/10.1186/s41073-023-00129-1","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate how strongly Australian university codes of research conduct endorse responsible research practices.</p><p><strong>Methods: </strong>Codes of research conduct from 25 Australian universities active in health and medical research were obtained from public websites, and audited against 19 questions to assess how strongly they (1) defined research integrity, research quality, and research misconduct, (2) required research to be approved by an appropriate ethics committee, (3) endorsed 9 responsible research practices, and (4) discouraged 5 questionable research practices.</p><p><strong>Results: </strong>Overall, a median of 10 (IQR 9 to 12) of 19 practices covered in the questions were mentioned, weakly endorsed, or strongly endorsed. Five to 8 of 9 responsible research practices were mentioned, weakly, or strongly endorsed, and 3 questionable research practices were discouraged. Results are stratified by Group of Eight (n = 8) and other (n = 17) universities. Specifically, (1) 6 (75%) Group of Eight and 11 (65%) other codes of research conduct defined research integrity, 4 (50%) and 8 (47%) defined research quality, and 7 (88%) and 16 (94%) defined research misconduct. (2) All codes required ethics approval for human and animal research. (3) All codes required conflicts of interest to be declared, but there was variability in how strongly other research practices were endorsed. The most commonly endorsed practices were ensuring researcher training in research integrity [8 (100%) and 16 (94%)] and making study data publicly available [6 (75%) and 12 (71%)]. The least commonly endorsed practices were making analysis code publicly available [0 (0%) and 0 (0%)] and registering analysis protocols [0 (0%) and 1 (6%)]. (4) Most codes discouraged fabricating data [5 (63%) and 15 (88%)], selectively deleting or modifying data [5 (63%) and 15 (88%)], and selective reporting of results [3 (38%) and 15 (88%)]. No codes discouraged p-hacking or hypothesising after results are known.</p><p><strong>Conclusions: </strong>Responsible research practices could be more strongly endorsed by Australian university codes of research conduct. Our findings may not be generalisable to smaller universities, or those not active in health and medical research.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9591647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender differences in peer reviewed grant applications, awards, and amounts: a systematic review and meta-analysis.","authors":"Karen B Schmaling, Stephen A Gallo","doi":"10.1186/s41073-023-00127-3","DOIUrl":"https://doi.org/10.1186/s41073-023-00127-3","url":null,"abstract":"<p><strong>Background: </strong>Differential participation and success in grant applications may contribute to women's lesser representation in the sciences. This study's objective was to conduct a systematic review and meta-analysis to address the question of gender differences in grant award acceptance rates and reapplication award acceptance rates (potential bias in peer review outcomes) and other grant outcomes.</p><p><strong>Methods: </strong>The review was registered on PROSPERO (CRD42021232153) and conducted in accordance with PRISMA 2020 standards. We searched Academic Search Complete, PubMed, and Web of Science for the timeframe 1 January 2005 to 31 December 2020, and forward and backward citations. Studies were included that reported data, by gender, on any of the following: grant applications or reapplications, awards, award amounts, award acceptance rates, or reapplication award acceptance rates. Studies that duplicated data reported in another study were excluded. Gender differences were investigated by meta-analyses and generalized linear mixed models. Doi plots and LFK indices were used to assess reporting bias.</p><p><strong>Results: </strong>The searches identified 199 records, of which 13 were eligible. An additional 42 sources from forward and backward searches were eligible, for a total of 55 sources with data on one or more outcomes. The data from these studies ranged from 1975 to 2020: 49 sources were published papers and six were funders' reports (the latter were identified by forwards and backwards searches). Twenty-nine studies reported person-level data, 25 reported application-level data, and one study reported both: person-level data were used in analyses. Award acceptance rates were 1% higher for men, which was not significantly different from women (95% CI 3% more for men to 1% more for women, k = 36, n = 303,795 awards and 1,277,442 applications, I<sup>2</sup> = 84%). Reapplication award acceptance rates were significantly higher for men (9%, 95% CI 18% to 1%, k = 7, n = 7319 applications and 3324 awards, I<sup>2</sup> = 63%). Women received smaller award amounts (g = -2.28, 95% CI -4.92 to 0.36, k = 13, n = 212,935, I<sup>2</sup> = 100%).</p><p><strong>Conclusions: </strong>The proportions of women that applied for grants, re-applied, accepted awards, and accepted awards after reapplication were less than the proportion of eligible women. However, the award acceptance rate was similar for women and men, implying no gender bias in this peer reviewed grant outcome. Women received smaller awards and fewer awards after re-applying, which may negatively affect continued scientific productivity. Greater transparency is needed to monitor and verify these data globally.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9762431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigating and preventing scientific misconduct using Benford's Law.","authors":"Gregory M Eckhartt, Graeme D Ruxton","doi":"10.1186/s41073-022-00126-w","DOIUrl":"10.1186/s41073-022-00126-w","url":null,"abstract":"<p><p>Integrity and trust in that integrity are fundamental to academic research. However, procedures for monitoring the trustworthiness of research, and for investigating cases where concern about possible data fraud have been raised are not well established. Here we suggest a practical approach for the investigation of work suspected of fraudulent data manipulation using Benford's Law. This should be of value to both individual peer-reviewers and academic institutions and journals. In this, we draw inspiration from well-established practices of financial auditing. We provide synthesis of the literature on tests of adherence to Benford's Law, culminating in advice of a single initial test for digits in each position of numerical strings within a dataset. We also recommend further tests which may prove useful in the event that specific hypotheses regarding the nature of data manipulation can be justified. Importantly, our advice differs from the most common current implementations of tests of Benford's Law. Furthermore, we apply the approach to previously-published data, highlighting the efficacy of these tests in detecting known irregularities. Finally, we discuss the results of these tests, with reference to their strengths and limitations.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"8 1","pages":"1"},"PeriodicalIF":7.2,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9290217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle B Rice, Ba' Pham, Justin Presseau, Andrea C Tricco, David Moher
{"title":"Correction: Characteristics of 'mega' peer-reviewers.","authors":"Danielle B Rice, Ba' Pham, Justin Presseau, Andrea C Tricco, David Moher","doi":"10.1186/s41073-022-00124-y","DOIUrl":"https://doi.org/10.1186/s41073-022-00124-y","url":null,"abstract":"","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":" ","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving equity, diversity, and inclusion in academia.","authors":"Omar Dewidar, Nour Elmestekawy, Vivian Welch","doi":"10.1186/s41073-022-00123-z","DOIUrl":"https://doi.org/10.1186/s41073-022-00123-z","url":null,"abstract":"<p><p>There are growing bodies of evidence demonstrating the benefits of equity, diversity, and inclusion (EDI) on academic and organizational excellence. In turn, some editors have stated their desire to improve the EDI of their journals and of the wider scientific community. The Royal Society of Chemistry established a minimum set of requirements aimed at improving EDI in scholarly publishing. Additionally, several resources were reported to have the potential to improve EDI, but their effectiveness and feasibility are yet to be determined. In this commentary we suggest six approaches, based on the Royal Society of Chemistry set of requirements, that journals could implement to improve EDI. They are: (1) adopt a journal EDI statement with clear, actionable steps to achieve it; (2) promote the use of inclusive and bias-free language; (3) appoint a journal's EDI director or lead; (4) establish a EDI mentoring approach; (5) monitor adherence to EDI principles; and (6) publish reports on EDI actions and achievements. We also provide examples of journals that have implemented some of these strategies, and discuss the roles of peer reviewers, authors, researchers, academic institutes, and funders in improving EDI.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":" ","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40470381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William T. Gattrell, Amrit Pali Hungin, Amy Price, Christopher C. Winchester, David Tovey, Ellen L. Hughes, Esther J. van Zuuren, Keith Goldman, Patricia Logullo, Robert Matheis, Niall Harrison
{"title":"ACCORD guideline for reporting consensus-based methods in biomedical research and clinical practice: a study protocol","authors":"William T. Gattrell, Amrit Pali Hungin, Amy Price, Christopher C. Winchester, David Tovey, Ellen L. Hughes, Esther J. van Zuuren, Keith Goldman, Patricia Logullo, Robert Matheis, Niall Harrison","doi":"10.1186/s41073-022-00122-0","DOIUrl":"https://doi.org/10.1186/s41073-022-00122-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Structured, systematic methods to formulate consensus recommendations, such as the Delphi process or nominal group technique, among others, provide the opportunity to harness the knowledge of experts to support clinical decision making in areas of uncertainty. They are widely used in biomedical research, in particular where disease characteristics or resource limitations mean that high-quality evidence generation is difficult. However, poor reporting of methods used to reach a consensus – for example, not clearly explaining the definition of consensus, or not stating how consensus group panellists were selected – can potentially undermine confidence in this type of research and hinder reproducibility. Our objective is therefore to systematically develop a reporting guideline to help the biomedical research and clinical practice community describe the methods or techniques used to reach consensus in a complete, transparent, and consistent manner.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The ACCORD (ACcurate COnsensus Reporting Document) project will take place in five stages and follow the EQUATOR Network guidance for the development of reporting guidelines. In Stage 1, a multidisciplinary Steering Committee has been established to lead and coordinate the guideline development process. In Stage 2, a systematic literature review will identify evidence on the quality of the reporting of consensus methodology, to obtain potential items for a reporting checklist. In Stage 3, Delphi methodology will be used to reach consensus regarding the checklist items, first among the Steering Committee, and then among a broader Delphi panel comprising participants with a range of expertise, including patient representatives. In Stage 4, the reporting guideline will be finalised in a consensus meeting, along with the production of an Explanation and Elaboration (E&E) document. In Stage 5, we plan to publish the reporting guideline and E&E document in open-access journals, supported by presentations at appropriate events. Dissemination of the reporting guideline, including a website linked to social media channels, is crucial for the document to be implemented in practice.</p><h3 data-test=\"abstract-sub-heading\">Discussion</h3><p>The ACCORD reporting guideline will provide a set of minimum items that should be reported about methods used to achieve consensus, including approaches ranging from simple unstructured opinion gatherings to highly structured processes.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138529742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What works for peer review and decision-making in research funding: a realist synthesis.","authors":"Alejandra Recio-Saucedo, Ksenia Crane, Katie Meadmore, Kathryn Fackrell, Hazel Church, Simon Fraser, Amanda Blatch-Jones","doi":"10.1186/s41073-022-00120-2","DOIUrl":"10.1186/s41073-022-00120-2","url":null,"abstract":"<p><strong>Introduction: </strong>Allocation of research funds relies on peer review to support funding decisions, and these processes can be susceptible to biases and inefficiencies. The aim of this work was to determine which past interventions to peer review and decision-making have worked to improve research funding practices, how they worked, and for whom.</p><p><strong>Methods: </strong>Realist synthesis of peer-review publications and grey literature reporting interventions in peer review for research funding.</p><p><strong>Results: </strong>We analysed 96 publications and 36 website sources. Sixty publications enabled us to extract stakeholder-specific context-mechanism-outcomes configurations (CMOCs) for 50 interventions, which formed the basis of our synthesis. Shorter applications, reviewer and applicant training, virtual funding panels, enhanced decision models, institutional submission quotas, applicant training in peer review and grant-writing reduced interrater variability, increased relevance of funded research, reduced time taken to write and review applications, promoted increased investment into innovation, and lowered cost of panels.</p><p><strong>Conclusions: </strong>Reports of 50 interventions in different areas of peer review provide useful guidance on ways of solving common issues with the peer review process. Evidence of the broader impact of these interventions on the research ecosystem is still needed, and future research should aim to identify processes that consistently work to improve peer review across funders and research contexts.</p>","PeriodicalId":74682,"journal":{"name":"Research integrity and peer review","volume":"7 1","pages":"2"},"PeriodicalIF":7.2,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65775168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}