Masayoshi Takamori, Hiroshi Irisawa, Yoshiteru Seo, Takashi Mizushima
{"title":"T<sub>2</sub>-mapping MRI Detects the Anaerobic Threshold for Flexion and Extension of the Wrist: Potential Use in Setting Rehabilitation Strength Targets.","authors":"Masayoshi Takamori, Hiroshi Irisawa, Yoshiteru Seo, Takashi Mizushima","doi":"10.2490/prm.20260037","DOIUrl":"10.2490/prm.20260037","url":null,"abstract":"<p><strong>Objectives: </strong>Upper-limb weakness significantly impairs activities of daily living in individuals with neurological disorders. Exercise at the anaerobic threshold or higher is recommended for efficient training and rehabilitation in such cases. Given a lack of standardized, non-invasive methods to assess the anaerobic threshold for small muscles in clinical practice, we used T<sub>2</sub>-mapping magnetic resonance imaging (MRI) and cumulative frequency curves of Z values (CFZ) to detect a minimum exercise strength target for physical rehabilitation of forearm muscles above the anaerobic threshold.</p><p><strong>Methods: </strong>T<sub>2</sub> values for ten forearm muscles in 13 healthy adult volunteers were obtained in the resting state and after isotonic flexion and extension of the wrist. T<sub>2</sub> was normalized by Z = (T<sub>2e </sub>- T<sub>2r</sub>)/SD<sub>r</sub>, where T<sub>2e</sub> is T<sub>2</sub> after exercise, and T<sub>2r</sub> and SD<sub>r</sub> are the mean and standard deviation of T<sub>2</sub> at rest.</p><p><strong>Results: </strong>In the horizontal direction exercise, the sensitivity values and CFZ of four out of five agonist muscles did not increase, nor shift, showing that these muscles were contracted by the aerobic metabolism. In the vertical direction exercise, in four of five agonist muscles and in two synergist muscles, the sensitivity values increased to about 50% and the CFZ was shifted to the right, indicating that these muscles were contracted by the anaerobic metabolism.</p><p><strong>Conclusions: </strong>Vertical direction exercise without extra weight can provide a minimum exercise strength that is higher than the anaerobic threshold. T<sub>2</sub>-mapping MRI is useful for setting exercise strength targets in the physical rehabilitation of small muscles.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260037"},"PeriodicalIF":1.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13369466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148458063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra- and Inter-examiner Reliability of Quantitative Sensory Testing of Knee Joints in Healthy Subjects.","authors":"Rikumi Kurahashi, Naoki Deguchi, Junji Nishimoto","doi":"10.2490/prm.20260036","DOIUrl":"10.2490/prm.20260036","url":null,"abstract":"<p><strong>Objectives: </strong>Examiner reliability of dynamic quantitative sensory testing (QST) of the knee varies across studies, and the optimal assessment site remains unclear. This study aimed to examine the intra- and inter-examiner reliability of QST performed at the medial joint space of the knee.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 30 healthy adults. QST was assessed at the medial knee joint space using the following measures: pressure pain threshold (PPT) for static QST and temporal summation (TS) and conditioned pain modulation (CPM) for dynamic QST. Two examiners performed each measurement twice on the same day. Intra-examiner reliability was evaluated using intraclass correlation coefficients [ICC (1, k)], and inter-examiner reliability was evaluated using ICC (2, k) and ICC (3, k).</p><p><strong>Results: </strong>The intra-examiner reliability ICCs for Examiners A/B were 0.98/0.99 for PPT, 0.81/0.88 for TS, 0.79/0.90 for CPM absolute change, and 0.84/0.95 for CPM percentage change. Inter-examiner reliability showed ICC (2, k)/ICC (3, k) values of 0.89/0.91 for PPT, 0.91/0.91 for TS, 0.66/0.66 for CPM absolute change, and 0.64/0.64 for CPM percentage change.</p><p><strong>Conclusions: </strong>This exploratory study suggested that QST performed at the medial joint space of the knee exhibited good intra- and inter-examiner reliability, with low variability compared to previously reported assessment sites. These preliminary findings indicate a potential advantage of this location for assessing knee pain. Future studies are needed to verify the clinical validity and applicability of these findings in patients with knee disorders.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260036"},"PeriodicalIF":1.3,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13366096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chihiro Oyamada, Junichiro Ishii, Tetsuo Kaminai, Naoki Shoda, Jun Hirose, Shinji Mishima, Song Ho Chang
{"title":"Impact of Imaging Height on Diagnostic Accuracy of the \"Too Many Toes\" Sign in Flatfoot.","authors":"Chihiro Oyamada, Junichiro Ishii, Tetsuo Kaminai, Naoki Shoda, Jun Hirose, Shinji Mishima, Song Ho Chang","doi":"10.2490/prm.20260035","DOIUrl":"10.2490/prm.20260035","url":null,"abstract":"<p><strong>Objectives: </strong>The \"too many toes\" sign is a clinical indicator for evaluating flatfoot. However, standardized assessment conditions remain undefined. In rehabilitation settings, this sign is used to monitor alignment, functional progression, and response to interventions such as intrinsic foot muscle training and gait retraining. Despite its widespread use, the height at which images are obtained may affect diagnostic interpretation. This study aimed to clarify the influence of imaging height on the assessment of the \"too many toes\" sign in patients with flatfoot.</p><p><strong>Methods: </strong>In this cross-sectional observational study, 11 patients with flatfoot were evaluated preoperatively. Standing photographs were captured at floor level and at 40-cm height behind the participants. The horizontal distance between the lateral malleolus and the fifth toe was measured using ImageJ. Two board-certified foot-and-ankle surgeons assessed the presence of the \"too many toes\" sign. Statistical comparisons were performed using <i>t</i>-tests and a McNemar test.</p><p><strong>Results: </strong>The mean horizontal distance from the lateral malleolus to the fifth toe significantly increased from 0.47 ± 0.13 cm at floor level to 0.59 ± 0.15 cm at 40-cm height. From the floor-level images, two cases were classified as positive for the \"too many toes\" sign and nine as negative. Conversely, images obtained at 40-cm height identified ten positive and one negative case.</p><p><strong>Conclusions: </strong>Imaging height significantly influences the visibility of the lateral toes and assessment of the \"too many toes\" sign in flatfoot, highlighting the need to standardize camera height for consistent clinical evaluations.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260035"},"PeriodicalIF":1.3,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13337338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Inpatient Moderate-to-vigorous Physical Activity and Functional Recovery following Lung Resection for Neoplastic Lung Diseases.","authors":"Taizo Goya, Taro Naka, Natsuko Takara, Tomonori Furugen, Takao Teruya, Kojiro Furukawa, Naoki Yamada","doi":"10.2490/prm.20260034","DOIUrl":"10.2490/prm.20260034","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated whether moderate-to-vigorous physical activity (MVPA) in patients after pulmonary resection is significantly associated with the 6-min walking distance recovery rate (6MWD-RR).</p><p><strong>Methods: </strong>A single-center retrospective cohort study was conducted between October 2017 and March 2020. Of the 114 patients who underwent pulmonary resection for neoplastic lung disease, 60 were included in the final analysis. The 6-min walk test was performed preoperatively and before discharge. The 6MWD-RR was calculated as (postoperative 6MWD/preoperative 6MWD) × 100. Participants were classified into High (6MWD-RR ≥90%) and Low (6MWD-RR <90%) RR groups. Postoperative MVPA was measured using a triaxial accelerometer after chest tubes were removed. Multivariate logistic regression analysis was used to examine the association between %MVPA (MVPA [min/day]/wearing time [min/day] × 100) and 6MWD-RR.</p><p><strong>Results: </strong>The High- and Low-RR groups comprised 39 (26 men, 67%) and 21 (9 men, 43%) patients, respectively. In the multivariate logistic regression analysis adjusted for age, sex, and preoperative factors (forced vital capacity %predicted, 6MWD, quadriceps strength), a higher %MVPA was significantly associated with a higher 6MWD-RR (odds ratio 1.38, 95% confidence interval 1.08-1.87).</p><p><strong>Conclusions: </strong>Higher postoperative %MVPA was associated with better functional recovery at discharge after lung resection. Further studies are required to clarify the causal relationships and to establish effective postoperative rehabilitation strategies.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260034"},"PeriodicalIF":1.3,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148378381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroshi Mano, Kenichi Kitamura, Wakako Hakiri, Kenji Shimizu, Chihiro Mano
{"title":"Significance of Advocacy Group Meetings for Rare and Intractable Diseases: A Survey of Joubert Syndrome and Related Disorders in Japan.","authors":"Hiroshi Mano, Kenichi Kitamura, Wakako Hakiri, Kenji Shimizu, Chihiro Mano","doi":"10.2490/prm.20260033","DOIUrl":"10.2490/prm.20260033","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260033"},"PeriodicalIF":1.3,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13311053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Influencing Upper-limb Spasticity in Post-stroke Patients during Convalescent Rehabilitation: A Single-center Retrospective Study.","authors":"Hiroaki Tamashiro, Naoki Urushidani, Keiko Okita, Takatsugu Okamoto","doi":"10.2490/prm.20260032","DOIUrl":"10.2490/prm.20260032","url":null,"abstract":"<p><strong>Objectives: </strong>This study characterized the joint-specific time course of upper-limb spasticity to identify predictors of subsequent spasticity progression in post-stroke patients undergoing inpatient rehabilitation in a convalescent (Kaifukuki) rehabilitation ward (KRW).</p><p><strong>Methods: </strong>This single-center retrospective cohort study included 76 post-stroke patients with upper-limb paresis admitted to a KRW between January and December 2020. Spasticity of the elbow, wrist, and finger flexors was assessed monthly using the Modified Ashworth Scale (MAS) at 1-4 months after admission. Upper-limb motor function and neurological findings, including tendon reflexes, were evaluated at admission. Motor recovery was classified using the Brunnstrom recovery stage (BRS). Multivariate logistic regression analysis was used to identify factors associated with increased finger flexor spasticity (MAS ≥1+) at discharge.</p><p><strong>Results: </strong>Upper-limb spasticity increased 2 months after admission, with earlier increases observed in distal joints when compared with proximal joints. By discharge, approximately one-third of patients demonstrated increased spasticity. At 3 months after admission, increased spasticity was most frequent in patients with BRS3 (upper limb, 59%; hand/fingers, 84%). Multivariate analysis revealed that lower Fugl-Meyer Assessment scores of the upper extremity and greater tendon reflex hyperreflexia at admission were independently associated with increased finger flexor spasticity at discharge.</p><p><strong>Conclusions: </strong>Upper-limb spasticity tended to increase earlier in distal joints, particularly in the wrist and finger flexors, than in the proximal joint during subacute inpatient rehabilitation. Severe upper-limb paresis and tendon reflex hyperreflexia at admission may be risk factors for worsening finger spasticity.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260032"},"PeriodicalIF":1.3,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13296371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validation and Distribution Characteristics of the Grading of Lateropulsion in Patients with Infratentorial Stroke: A Preliminary Study.","authors":"Tatsuya Igarashi, Shingo Hirano, Taisei Inoue, Shogo Fukumoto, Mamoru Igawa, Reika Yoshida, Toshiya Nezu, Osuke Shibata, Shota Hayashi, Kozo Ueta, Tsubasa Mitsutake","doi":"10.2490/prm.20260031","DOIUrl":"10.2490/prm.20260031","url":null,"abstract":"<p><strong>Objectives: </strong>Body lateropulsion (BL) is a postural orientation disorder after stroke, characterized by an involuntary tilt of the body to one side. We aimed to evaluate the validity of the Grading of Lateropulsion (GoL)-a measure of BL severity-by examining its associations with balance, ataxia, and walking ability in patients with infratentorial stroke. We also assessed the distribution characteristics of GoL scores.</p><p><strong>Methods: </strong>We evaluated 21 patients with infratentorial stroke who presented with BL using the Berg Balance Scale (BBS), subjective visual vertical, Scale for the Assessment and Rating of Ataxia (SARA), and Functional Ambulation Category (FAC). We then analyzed the correlations between these measures and GoL. We also calculated the proportions of patients with the lowest and highest GoL scores. In patients who completed the 1-month follow-up, FAC scores were compared between baseline and follow-up.</p><p><strong>Results: </strong>Significant correlations with GoL were observed for BBS, SARA, and FAC. GoL Grade 1 was observed in 57.1% of the patients and Grade 4 in 28.6%, suggesting the presence of both floor and ceiling effects. The median FAC score increased from 4 at baseline to 5 at follow-up, demonstrating a significant improvement.</p><p><strong>Conclusions: </strong>GoL severity was strongly associated with ataxia, balance function, and walking independence, indicating a complex and multifactorial pathophysiology of BL. However, notable floor and ceiling effects as well as the negatively skewed distribution of GoL scores indicated limited sensitivity for detecting subtle changes in BL severity.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260031"},"PeriodicalIF":1.3,"publicationDate":"2026-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13278827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Motoric Cognitive Risk Syndrome and Its Components with Health Indicators in Community-dwelling Older Adults: A Cross-sectional Study.","authors":"Takafumi Kinoshita, Kensuke Matsuda, Takuro Ikeda","doi":"10.2490/prm.20260030","DOIUrl":"10.2490/prm.20260030","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine the associations between motoric cognitive risk syndrome (MCR), its component subjective cognitive decline (SCD), and health-related indicators among community-dwelling older adults.</p><p><strong>Methods: </strong>This cross-sectional study included community-dwelling older adults. MCR was defined as the presence of SCD and slow gait speed. Health-related indicators included the Questionnaire for Medical Checkup of the Old-Old (QMCOO), physical frailty, and social frailty. Participants were divided into three groups according to MCR components: a healthy group, a group with SCD, and an MCR group. Basic characteristics and health-related indicators of the groups were compared. Multivariate regression analyses were performed with QMCOO, physical frailty, and social frailty as dependent variables and MCR and SCD as independent variables.</p><p><strong>Results: </strong>Among the 138 participants included in the analysis, 41 (29.7%) belonged to the healthy group, 82 (59.4%) to the SCD group, and 15 (10.9%) to the MCR group. In the multivariate regression analysis, QMCOO was significantly associated with MCR (β = 0.217, P = 0.011) and SCD (β = 0.190, P = 0.022). MCR was significantly associated with physical frailty (odds ratio =19.495, P <0.001) but showed no significant association with social frailty. In contrast, SCD was not significantly associated with either frailty type.</p><p><strong>Conclusions: </strong>MCR and SCD were significantly associated with existing health-related indicators, suggesting their potential utility as markers for early detection of health deterioration in older adults.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260030"},"PeriodicalIF":1.3,"publicationDate":"2026-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13261317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stabilizer Orthosis Rehabilitation after Bilateral Hip Disarticulation Due to Necrotizing Fasciitis: A Case Report and Literature Review.","authors":"Kei Sato, Yasuhiro Kajiwara, Motoaki Oshima, Tatsuya Fujii, Hideaki Takahata","doi":"10.2490/prm.20260029","DOIUrl":"10.2490/prm.20260029","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260029"},"PeriodicalIF":1.3,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report on Balance Progress in a Patient with Body Lateropulsion: Focusing on Vestibulo-ocular Reflex and Subjective Visual Vertical.","authors":"Kazusa Saisu, Tatsuya Igarashi, Shota Hayashi, Tomohiko Kamo","doi":"10.2490/prm.20260028","DOIUrl":"10.2490/prm.20260028","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"11 ","pages":"20260028"},"PeriodicalIF":1.3,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13231061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148166120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}