Principles and practice of clinical research (2015)最新文献_第7页

Can neural markers be used for fibromyalgia clinical management? 神经标志物可以用于纤维肌痛的临床管理吗？

Principles and practice of clinical research (2015) Pub Date : 2022-01-01 Epub Date: 2022-04-24 DOI: 10.21801/ppcrj.2022.81.5

Luis Castelo-Branco, Alejandra Cardenas-Rojas, Kevin Pacheco-Barrios, Paulo E P Teixeira, Paola Gonzalez-Mego, Karen Vasquez-Avila, Pablo Costa Cortez, Anna Marduy, Ingrid Rebello-Sanchez, Joao Parente, Sammer Marzouk, Felipe Fregni

引用次数: 2

Deferasirox on COVID-19: safety and efficacy of iron-chelating therapy. A multicentric, randomized, triple blinded study 去甲拉罗司治疗新冠肺炎：铁疗法的安全性和有效性。一项多中心、随机、三盲研究

Principles and practice of clinical research (2015) Pub Date : 2021-12-31 DOI: 10.21801/ppcrj.2021.74.5

Natália Garcia, A. Gutierrez-Martinez, Elly Pichardo, Irvianny Madera, Lorgis Jiménez, Nicolle Batlle, Katherine Calderón

引用次数: 0

The effect of regenerative therapy in functional outcome in the treatment of patellar and Achilles tendinopathy: A Meta-analysis of Randomized Controlled Clinical Trials 再生疗法对治疗髌骨和跟腱病的功能结局的影响:随机对照临床试验的荟萃分析

Principles and practice of clinical research (2015) Pub Date : 2021-12-31 DOI: 10.21801/ppcrj.2021.74.4

Guillermo Droppelmann, Akira Saavedra, Felipe Apablaza, A. Macedo

引用次数: 0

A Practical Guide to Perform a Systematic Literature Review and Meta-analysis 进行系统文献综述和荟萃分析的实用指南

Principles and practice of clinical research (2015) Pub Date : 2021-12-31 DOI: 10.21801/ppcrj.2021.74.6

A. F. Herrera Ortiz, Eduard Cadavid Camacho, Julián Cubillos Rojas, Tatiana Cadavid Camacho, Stephani Zoe Guevara, Nury Tatiana Rincón Cuenca, Andrés Vásquez Perdomo, Valeria del Castillo Herazo, Rubén Giraldo Malo

引用次数: 10

Acceptance towards COVID-19 vaccine: A cross-sectional study in the Dominican Republic. 对COVID-19疫苗的接受:多米尼加共和国的一项横断面研究

Principles and practice of clinical research (2015) Pub Date : 2021-12-31 DOI: 10.21801/ppcrj.2021.74.7

María Isabel Marte, Elly Pichardo, Vahid Nouri Kandany, Máxima Méndez Castillo

引用次数: 1

Competency-Based Self-Assessment Tools: A Mixed-Methods Retrospective Analysis of Need. 基于能力的自我评估工具:需求的混合方法回顾性分析。

Principles and practice of clinical research (2015) Pub Date : 2021-12-26 DOI: 10.21801/ppcrj.2021.74.3

P. Trinh, Barbara Tafuto, Yasheca T Ebanks, Zahra Zunaed, D. Lechner

{"title":"Competency-Based Self-Assessment Tools: A Mixed-Methods Retrospective Analysis of Need.","authors":"P. Trinh, Barbara Tafuto, Yasheca T Ebanks, Zahra Zunaed, D. Lechner","doi":"10.21801/ppcrj.2021.74.3","DOIUrl":"https://doi.org/10.21801/ppcrj.2021.74.3","url":null,"abstract":"Quality research management is the cornerstone of clinical and translational science. In 2006, the NIH National Center for Advancing Translational Sciences (NCATS) created the Clinical and Translational Science Awards (CTSA) program to train new generations of clinical and translational researchers (Patel et al., 2019). While 60+ academic medical centers have created workforce development programs through CTSA funding, evaluating the use and comparative efficacy of competency-based assessment tools to understand the effectiveness of these programs has remained unreported. Competency-based selfassessment tools (CBSTs) are question-based instruments to evaluate one’s confidence in specific professional competencies with an implicit assumption that confidence may translate into competency (Robinson et al., 2013). CBSTs would allow programs to measure indirectly key professional development milestones of trainees. Currently, several CBSTs exist to assess individuals in specific clinical research roles, such as principal investigator, clinical research coordinator, and other ancillary research staff (Hornung, Ianni, Jones, Samuels, & Ellingrod, 2019; Hornung et al., 2018; Mullikin, Bakken, & Betz, 2007), but little has been reported about the use or need for CBSTs within the CTSA community. Consequently, the New Jersey Alliance for Clinical and Translational Science (NJ ACTS) Workforce Development Core conducted a CTSA consortium-wide assessment to evaluate the present use and potential need for CBSTs in evaluating CTSA trainees. This work is a retrospective analysis of those materials, conducted to understand both the utility of CBSTs as an evaluation component to CTSA workforce development activities and which professional competencies are valued.","PeriodicalId":74496,"journal":{"name":"Principles and practice of clinical research (2015)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90387365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerating the translation of research findings to clinical practice: insights from phantom limb pain clinical trials. 加速将研究成果转化为临床实践:来自幻肢痛临床试验的见解。

Principles and practice of clinical research (2015) Pub Date : 2021-12-22 DOI: 10.21801/ppcrj.2021.74.1

K. Pacheco-Barrios, Paulo S de Melo, Karen Vásquez-Ávila, A. Cardenas-Rojas, Paola Gonzalez-Mego, A. Marduy, Joao Parente, Ingrid Rebello Sanchez, P. Cortêz, Meghan Whalen, L. Castelo-Branco, F. Fregni

{"title":"Accelerating the translation of research findings to clinical practice: insights from phantom limb pain clinical trials.","authors":"K. Pacheco-Barrios, Paulo S de Melo, Karen Vásquez-Ávila, A. Cardenas-Rojas, Paola Gonzalez-Mego, A. Marduy, Joao Parente, Ingrid Rebello Sanchez, P. Cortêz, Meghan Whalen, L. Castelo-Branco, F. Fregni","doi":"10.21801/ppcrj.2021.74.1","DOIUrl":"https://doi.org/10.21801/ppcrj.2021.74.1","url":null,"abstract":"Phantom limb pain (PLP) is defined as a painful sensation in an amputated limb or pain that follows partial or complete deafferentation. It belongs to a group of neuropathic pain syndromes, and its treatment is challenging and often refractory to many modalities, causing significant burden and suffering. The prevalence of PLP after amputation ranges between 60–80% (Limakatso et al., 2020). In some cases, the pain might decrease with time and even fade away, but studies have shown that even after two years, a majority of the patients still present pain, and only a small percentage have reported a decrease in intensity of pain (Erlenwein et al., 2021). To date, there is no guidelines for the treatment of PLP and most therapies have low levels of evidence. Possible treatments include the use of pharmacotherapy including opioids, antidepressants, neuroleptics, muscle relaxants and anticonvulsants (Flor, 2002), a variety of surgical procedures (Nikolajsen & Christensen, 2015), nerve blocks, local anesthesia, transcutaneous electrical nerve stimulation (TENS) (Kern et al., 2012), acupuncture, psychological interventions, physiotherapy, and mind-body techniques such as hypnosis(Bamford, 2006; Moura et al., 2012). Conventional treatments used for PLP, such as pharmacologic agents, have pertinent limitations. The use of pharmacologic agents for controlling pain is associated with several side effects and can become unsustainable in the long term (Els et al.,","PeriodicalId":74496,"journal":{"name":"Principles and practice of clinical research (2015)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75756584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

MusT-In Therapy (Effect of Music Therapy and Interaction with Typically Developing Peers) for improving social interaction in children with severe autism spectrum disorder - Study protocol. MusT In Therapy（音乐治疗和与典型发育中同龄人的互动的效果）用于改善患有严重自闭症谱系障碍的儿童的社交互动-研究方案。

Principles and practice of clinical research (2015) Pub Date : 2021-12-19 DOI: 10.21801/ppcrj.2021.73.6

María J Romaris, Simone Collopy, Tatiana de Avila Miguel, Mohamed E A Abdelrahim, Carla Renata Curi, Mohammad Altujjar, Khalid Ahmed, Reynie Reynoso Gonel, Arthur Gomes da Silva Netto, Saulo Borges, Joao Paulo Greco de Freitas Cardoso, Ricardo Almeida-Magaña

引用次数: 0

Designing and conducting observational studies in rehabilitation: challenges and opportunities 设计和实施康复观察性研究:挑战和机遇

Principles and practice of clinical research (2015) Pub Date : 2021-12-19 DOI: 10.21801/ppcrj.2021.73.7

Sara P. Barbosa, L. M. Marques, K. Pacheco-Barrios, M. Imamura, L. Battistella, M. Simis, F. Fregni

引用次数: 3

Combination of olanzapine with bispectral index guided anesthesia to prevent postoperative delirium in elderly patients undergoing major gastrointestinal elective surgery: a randomized, double-blind, placebo-controlled study protocol 奥氮平联合双谱指数引导麻醉预防老年胃肠大手术患者术后谵妄:一项随机、双盲、安慰剂对照研究方案

Principles and practice of clinical research (2015) Pub Date : 2021-11-05 DOI: 10.21801/ppcrj.2021.73.5

Raquel Costa, Osama Zied Alzobi, S. Al-Busaidi, Diego Arbaje, Catherine Avery Skinner, Victor Batistella, Eleonora Boschetti Grutzmacher, Gabriela Casais, Denisse A. Castro, M. Cohen, Annette García Delgado, Muhammad Haseeb, Veronica Hernandez Leon, Pedro Hilton de Andrade Filho, Brahim Khouri Lopez, A. Marcadenti, J. Müller, Diego Noya Rabelo, Flavia Tarcha, Juliana Tepedino Martins Alves, Francisca Urrutia Goldsack, E. Youssif, A. Tamayo, D. Schwartz, D. D. Garcia Choza, M. Cubria, I. Sulieman

引用次数: 0