Precision cancer medicine最新文献

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The use of 18FDG PET/CT for radiotherapy treatment planning in non-small cell lung cancer: a mini review 18FDG PET/CT在非小细胞肺癌放疗计划中的应用综述
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-38
E. Gkika, A. Grosu, U. Nestle
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引用次数: 0
The role of concurrent amplification of PD-L1, PD-L2 and JAK2 in metastatic lung adenocarcinoma as a biomarker of immune checkpoint inhibitor response: a case report PD-L1、PD-L2和JAK2同时扩增在转移性肺腺癌中作为免疫检查点抑制剂反应的生物标志物的作用:一份病例报告
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-39
W. Phillips, A. Awan, B. Lo, A. Redway, G. Nicholas
{"title":"The role of concurrent amplification of PD-L1, PD-L2 and JAK2 in metastatic lung adenocarcinoma as a biomarker of immune checkpoint inhibitor response: a case report","authors":"W. Phillips, A. Awan, B. Lo, A. Redway, G. Nicholas","doi":"10.21037/pcm-22-39","DOIUrl":"https://doi.org/10.21037/pcm-22-39","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41352040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging drivers in non-small cell lung cancer, is there a role for immunotherapy?—a narrative review 癌症的新兴驱动因素,免疫疗法有作用吗-叙述性评论
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-33
L. Brunetti, V. Santo, M. Russano, Alessio Cortellini, A. Galletti, F. Citarella, G. D. Di Fazio, Alessia Vendittelli, Giulia La Cava, B. Vincenzi, G. Tonini, D. Santini
{"title":"Emerging drivers in non-small cell lung cancer, is there a role for immunotherapy?—a narrative review","authors":"L. Brunetti, V. Santo, M. Russano, Alessio Cortellini, A. Galletti, F. Citarella, G. D. Di Fazio, Alessia Vendittelli, Giulia La Cava, B. Vincenzi, G. Tonini, D. Santini","doi":"10.21037/pcm-22-33","DOIUrl":"https://doi.org/10.21037/pcm-22-33","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43519346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A challenge in emergency department: a case report of oxaliplatin-induced Kounis syndrome 急诊科的挑战:一例奥沙利铂诱发的库尼斯综合征病例报告
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-51
M. Albanesi, R. Didonna, N. Chaoul, Federica Mazzone, Marco Zurlo, F. Iacovelli, F. Monitillo, Flavio Rimmaudo, M. Tucci, M. Cives, C. Porta, V. Procacci
{"title":"A challenge in emergency department: a case report of oxaliplatin-induced Kounis syndrome","authors":"M. Albanesi, R. Didonna, N. Chaoul, Federica Mazzone, Marco Zurlo, F. Iacovelli, F. Monitillo, Flavio Rimmaudo, M. Tucci, M. Cives, C. Porta, V. Procacci","doi":"10.21037/pcm-22-51","DOIUrl":"https://doi.org/10.21037/pcm-22-51","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48180318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lung cancer surgery in women: focus on gender-related outcomes—a narrative review 女性癌症肺癌手术:关注与性别相关的结果——叙述性综述
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-23
C. Zirafa, G. Romano, E. Sicolo, A. Castaldi, F. Davini, F. Melfi
{"title":"Lung cancer surgery in women: focus on gender-related outcomes—a narrative review","authors":"C. Zirafa, G. Romano, E. Sicolo, A. Castaldi, F. Davini, F. Melfi","doi":"10.21037/pcm-22-23","DOIUrl":"https://doi.org/10.21037/pcm-22-23","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45349030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
First-line ALK inhibitors in treatment-naive advanced ALK rearranged non-small cell lung cancer: systematic review and network meta-analysis 一线ALK抑制剂治疗初治晚期ALK重排非小细胞肺癌:系统评价和网络荟萃分析
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-54
A. Tan, S. Tan, M. Ang, D. S. Tan
{"title":"First-line ALK inhibitors in treatment-naive advanced ALK rearranged non-small cell lung cancer: systematic review and network meta-analysis","authors":"A. Tan, S. Tan, M. Ang, D. S. Tan","doi":"10.21037/pcm-22-54","DOIUrl":"https://doi.org/10.21037/pcm-22-54","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45416396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarkers for immunotherapy in non-small cell lung cancer: a current and future reality 非小细胞肺癌免疫治疗的生物标志物:当前和未来的现实
Precision cancer medicine Pub Date : 2023-01-01 DOI: 10.21037/pcm-22-68
Alejandro Olivares-Hernández, J. Miramontes-González, Juan Luis García Hernández, E. del Barco Morillo, E. Fonseca-Sánchez
{"title":"Biomarkers for immunotherapy in non-small cell lung cancer: a current and future reality","authors":"Alejandro Olivares-Hernández, J. Miramontes-González, Juan Luis García Hernández, E. del Barco Morillo, E. Fonseca-Sánchez","doi":"10.21037/pcm-22-68","DOIUrl":"https://doi.org/10.21037/pcm-22-68","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47145516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroimaging aspects and clinical significance of giant perivascular spaces in the brain. 脑内巨大血管周围间隙的神经影像学特征及临床意义。
Precision cancer medicine Pub Date : 2022-12-30 DOI: 10.21037/pcm-22-27
Giuseppe Barisano
{"title":"Neuroimaging aspects and clinical significance of giant perivascular spaces in the brain.","authors":"Giuseppe Barisano","doi":"10.21037/pcm-22-27","DOIUrl":"https://doi.org/10.21037/pcm-22-27","url":null,"abstract":"The cerebral vasculature represents a major component of the brain, constituting 25–30% of the total brain volume (1) and providing essential support to the cells of the nervous system. The blood vessels penetrating or leaving the brain parenchyma present unique anatomical properties, including the presence of a fluid-filled perivascular compartment, known as perivascular space (PVS) or Virchow-Robin space. PVS physiological function is still not completely understood, but is thought to be related to the cerebrospinal/interstitial fluid circulation and the clearance of cerebral waste products. In fact, in recent years, PVS have been described as main pathways in clearance system models of the brain (2), and numerous studies reported the association between PVS alterations and several neurological diseases. As PVS follow the course of the penetrating blood vessels and have a tubular shape, they appear on magnetic resonance imaging (MRI) as lines or dots, based on the orientation of the PVS with respect to the image acquisition plane (parallel or perpendicular, respectively), and have a signal intensity similar to the cerebrospinal fluid (i.e., hypointense on T1-weighted images and hyperintense on T2-weighted images). PVS cross-sectional diameter is usually less than 2 mm and on MRI they are most commonly seen in the centrum semiovale and basal ganglia (3,4). Thanks to the improved resolution and signal-to-noise ratio, modern MRI scanners and sequences currently allow to visualize PVS in practically all individuals, including healthy young adults","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"5 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/4b/nihms-1828488.PMC9817033.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9078379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chinese expert consensus recommendations for management of bone health in female patients with early breast cancer (2022 edition) 癌症早期女性患者骨健康管理的中国专家共识建议(2022年版)
Precision cancer medicine Pub Date : 2022-12-01 DOI: 10.21037/pcm-22-57
{"title":"Chinese expert consensus recommendations for management of bone health in female patients with early breast cancer (2022 edition)","authors":"","doi":"10.21037/pcm-22-57","DOIUrl":"https://doi.org/10.21037/pcm-22-57","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44045946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prospective and single-blinded evaluation of the multi-cancer Carcimun-test 多癌carcimun试验的前瞻性和单盲评价
Precision cancer medicine Pub Date : 2022-06-01 DOI: 10.21037/pcm-21-35
A. Salat, W. Voigt, Berthold von und zu Zwerger
{"title":"Prospective and single-blinded evaluation of the multi-cancer Carcimun-test","authors":"A. Salat, W. Voigt, Berthold von und zu Zwerger","doi":"10.21037/pcm-21-35","DOIUrl":"https://doi.org/10.21037/pcm-21-35","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48942302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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