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Behavioral, Normative and Control Beliefs about Earthquake Preparedness: A Deductive Content Analysis Study. 地震防备的行为信念、规范信念和控制信念:演绎内容分析研究。
PLoS currents Pub Date : 2018-09-28 DOI: 10.1371/currents.dis.20fbad29d53fb164ac2699dc2736d804
Mehdi Najafi, Hamid Reza Khankeh, Helen Elmi, Negar Pourvakhshoori
{"title":"Behavioral, Normative and Control Beliefs about Earthquake Preparedness: A Deductive Content Analysis Study.","authors":"Mehdi Najafi,&nbsp;Hamid Reza Khankeh,&nbsp;Helen Elmi,&nbsp;Negar Pourvakhshoori","doi":"10.1371/currents.dis.20fbad29d53fb164ac2699dc2736d804","DOIUrl":"https://doi.org/10.1371/currents.dis.20fbad29d53fb164ac2699dc2736d804","url":null,"abstract":"<p><strong>Introduction: </strong>Despite efforts to increase earthquake preparedness (EP), the level of earthquake preparedness in Tehran is low, even when people acknowledge the risk they face. This problem has its roots in the beliefs of Tehran inhabitants about EP. This study is aimed to elicit the salient beliefs about earthquake preparedness among Tehran citizens.</p><p><strong>Method: </strong>This is a deductive content analysis research. The theory of planned behavior (TPB) has been applied as the theoretical framework of the study. 132 semi-structured interviews have been conducted with Tehran heads of households and the obtained data have been analyzed.</p><p><strong>Results: </strong>The interviews showed that the belief in the usefulness of the EP and the belief that \"the EP can cause anxiety among family members\" were the salient behavioral beliefs (the ones influencing the attitude towards a behavior). The main normative belief (which influences the subjective norms), was \"my family doesn't disagree with the EP\" although most of the interviewees did not know about their families' views. Finally, the main control belief (which is the basis of perceived behavioral control), was that \"education can facitilates EP\".</p><p><strong>Conclusion: </strong> Tehran inhabitants preparedness behaviors can be influenced by their behavioral, normative and control beliefs about preparedness. Recognition of these beliefs may assist policy makers and executives to develop a better understanding of the origins of the preparedness behaviors. Any interventions to change these behaviors should be made based on such knowledge. Key words: Earthquake; preparedness; salient beliefs; theory of planned behavior.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36598321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Routine to Rare Risk - A Case Study of Firecracker Explosion Disaster in India. 从常规到罕见风险——以印度鞭炮爆炸事故为例。
PLoS currents Pub Date : 2018-09-27 DOI: 10.1371/currents.dis.d5a27e47c8decbd4263813a15c47e07e
Faisel T Illiyas, Shibu K Mani
{"title":"Routine to Rare Risk - A Case Study of Firecracker Explosion Disaster in India.","authors":"Faisel T Illiyas,&nbsp;Shibu K Mani","doi":"10.1371/currents.dis.d5a27e47c8decbd4263813a15c47e07e","DOIUrl":"https://doi.org/10.1371/currents.dis.d5a27e47c8decbd4263813a15c47e07e","url":null,"abstract":"<p><strong>Introduction: </strong>In India quite a few religious festivals and cultural fairs are accompanied by public display of fireworks. The grandeur of the festivals is often evaluated by the common man with respect to its colorful firework displays. Firecracker accidents during mass fireworks at public display venues may be disastrous in its consequences and damages. A fire cracker disaster which occurred during a religious public firework display event at Puttingal in Kerala, India was documented and analyzed to figure out the safety concerns and good practices, towards making a reference for effective emergency management.</p><p><strong>Methods: </strong>The fire cracker incident was studied on the broader perspective of disaster management. Inputs from agencies involved in emergency response, casualty management, damage assessment and general administration as well as the perspective of victims and the public who witnessed the event was incorporated in to the study through participatory observation, field visits and face to face discussions.</p><p><strong>Result: </strong>The response followed by the firecracker explosion was analyzed in three phases based on the time frame of response. Influence of traditions and culture in firework organization, the mandatory legal requirements for firework displays and the current safety practices followed were evaluated in the background of this rare firecracker risk which turned out to be a major disaster in the state of Kerala in India.</p><p><strong>Conclusion: </strong>Public display of fireworks in Puttingal temple was organised despite of the legal permission from competitive authority. Negligence of law, non-sensitivity of public towards fire work safety, competitive nature of event organizers and social pressure from religious groups traversed the basic fire work safety requirements, ultimately triggered the largest fire cracker disaster in Kerala.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36714440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Knowing What We Know - Reflections on the Development of Technical Guidance for Loss Data for the Sendai Framework for Disaster Risk Reduction. 更正:了解我们所知道的--关于为仙台减少灾害风险框架制定损失数据技术指南的思考》。
PLoS currents Pub Date : 2018-09-24 DOI: 10.1371/currents.dis.e597ed667989b083254fefcac8853875
Plos Currents
{"title":"Correction: Knowing What We Know - Reflections on the Development of Technical Guidance for Loss Data for the Sendai Framework for Disaster Risk Reduction.","authors":"Plos Currents","doi":"10.1371/currents.dis.e597ed667989b083254fefcac8853875","DOIUrl":"https://doi.org/10.1371/currents.dis.e597ed667989b083254fefcac8853875","url":null,"abstract":"<p><p></p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36643347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Hurricane Sandy on HIV Testing Rates: An Interrupted Time Series Analysis, January 1, 2011‒December 31, 2013. 飓风桑迪对艾滋病毒检测率的影响:中断时间序列分析,2011年1月1日至2013年12月31日。
PLoS currents Pub Date : 2018-09-13 DOI: 10.1371/currents.dis.ea09f9573dc292951b7eb0cf9f395003
Linda I Ekperi, Erin Thomas, Tanya Telfair LeBlanc, Erica Elaine Adams, Grete E Wilt, Noelle-Angelique Molinari, Eric G Carbone
{"title":"The Impact of Hurricane Sandy on HIV Testing Rates: An Interrupted Time Series Analysis, January 1, 2011‒December 31, 2013.","authors":"Linda I Ekperi,&nbsp;Erin Thomas,&nbsp;Tanya Telfair LeBlanc,&nbsp;Erica Elaine Adams,&nbsp;Grete E Wilt,&nbsp;Noelle-Angelique Molinari,&nbsp;Eric G Carbone","doi":"10.1371/currents.dis.ea09f9573dc292951b7eb0cf9f395003","DOIUrl":"10.1371/currents.dis.ea09f9573dc292951b7eb0cf9f395003","url":null,"abstract":"<p><strong>Background: </strong>Hurricane Sandy made landfall on the eastern coast of the United States on October 29, 2012 resulting in 117 deaths and 71.4 billion dollars in damage. Persons with undiagnosed HIV infection might experience delays in diagnosis testing, status confirmation, or access to care due to service disruption in storm-affected areas. The objective of this study is to describe the impact of Hurricane Sandy on HIV testing rates in affected areas and estimate the magnitude and duration of disruption in HIV testing associated with storm damage intensity.</p><p><strong>Methods: </strong>Using MarketScan data from January 2011‒December 2013, this study examined weekly time series of HIV testing rates among privately insured enrollees not previously diagnosed with HIV; 95 weeks pre- and 58 weeks post-storm. Interrupted time series (ITS) analyses were estimated by storm impact rank (using FEMA's Final Impact Rank mapped to Core Based Statistical Areas) to determine the extent that Hurricane Sandy affected weekly rates of HIV testing immediately and the duration of that effect after the storm.</p><p><strong>Results: </strong>HIV testing rates declined significantly across storm impact rank areas. The mean decline in rates detected ranged between -5% (95% CI: -9.3, -1.5) in low impact areas and -24% (95% CI: -28.5, -18.9) in very high impact areas. We estimated at least 9,736 (95% CI: 7,540, 11,925) testing opportunities were missed among privately insured persons following Hurricane Sandy. Testing rates returned to baseline in low impact areas by 6 weeks post event (December 9, 2012); by 15 weeks post event (February 10, 2013) in moderate impact areas; and by 17 weeks after the event (February 24, 2013) in high and very high impact areas.</p><p><strong>Conclusions: </strong>Hurricane Sandy resulted in a detectable and immediate decline in HIV testing rates across storm-affected areas. Greater storm damage was associated with greater magnitude and duration of testing disruption. Disruption of basic health services, like HIV testing and treatment, following large natural and man-made disasters is a public health concern.  Disruption in testing services availability for any length of time is detrimental to the efforts of the current HIV prevention model, where status confirmation is essential to control disease spread.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36598320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Recent Trends in Unpasteurized Fluid Milk Outbreaks, Legalization, and Consumption in the United States. 美国未经高温消毒的液态奶爆发、合法化和消费的最新趋势。
PLoS currents Pub Date : 2018-09-13 DOI: 10.1371/currents.outbreaks.bae5a0fd685616839c9cf857792730d1
Joanne Whitehead, Bryony Lake
{"title":"Recent Trends in Unpasteurized Fluid Milk Outbreaks, Legalization, and Consumption in the United States.","authors":"Joanne Whitehead,&nbsp;Bryony Lake","doi":"10.1371/currents.outbreaks.bae5a0fd685616839c9cf857792730d1","DOIUrl":"https://doi.org/10.1371/currents.outbreaks.bae5a0fd685616839c9cf857792730d1","url":null,"abstract":"<p><strong>Introduction: </strong>Determining the potential risk of foodborne illness has become critical for informing policy decisions, due to the increasing availability and popularity of unpasteurized (raw) milk.</p><p><strong>Methods: </strong>Trends in foodborne illnesses reported to the Centers for Disease Control in the United States from 2005 to 2016 were analyzed, with comparison to state legal status and to consumption, as estimated by licensing records.</p><p><strong>Results: </strong>The rate of unpasteurized milk-associated outbreaks has been declining since 2010, despite increasing legal distribution. Controlling for growth in population and consumption, the outbreak rate has effectively decreased by 74% since 2005.</p><p><strong>Discussion: </strong>Studies of the role of on-farm food safety programs to promote the further reduction of unpasteurized milk outbreaks should be initiated, to investigate the efficacy of such risk management tools.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36550415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Exploratory Qualitative Study of Fire Preparedness Among High-rise Building Residents. 高层建筑居民火灾防范的探索性质的研究。
PLoS currents Pub Date : 2018-08-31 DOI: 10.1371/currents.dis.aa27444baa486dc3d5b3fa7c28009b22
Gary Glauberman, Kristine Qureshi
{"title":"Exploratory Qualitative Study of Fire Preparedness Among High-rise Building Residents.","authors":"Gary Glauberman,&nbsp;Kristine Qureshi","doi":"10.1371/currents.dis.aa27444baa486dc3d5b3fa7c28009b22","DOIUrl":"https://doi.org/10.1371/currents.dis.aa27444baa486dc3d5b3fa7c28009b22","url":null,"abstract":"<p><strong>Introduction: </strong>Fire hazards are an extreme risk to occupants of high-rise buildings. Little attention has been paid to emergency and evacuation preparedness among people living in high-rise buildings. This paper reports on emergency fire preparedness among residents of a high-rise building that has experienced multiple fires in the past.</p><p><strong>Methods: </strong>An exploratory qualitative pilot study was conducted using key informant interviews. Six residents participated. Themes on preparedness for fires and emergency evacuation were extracted.</p><p><strong>Results: </strong>Findings indicated varying levels of preparedness for fires and emergency evacuation among residents. Factors influencing residents' emergency preparedness included fire risk perception, owner or renter status, and building-level emergency preparedness. Fire alarms were considered to be an ineffective evacuation cue. Severe cues such as seeing fire or smoke were more likely to prompt evacuation. Participants provided a series of suggestions to keep high-rise residents safe during fire emergencies.</p><p><strong>Discussion: </strong>The study revealed fire preparedness knowledge, decision-making processes, and actual behaviors of residential high-rise occupants who experienced a fire emergency in their building. Main findings of the study are discussed in two themes: influences on fire emergency and evacuation preparedness, and evacuation decision-making and response to fire. Results from this pilot study will be used as the basis for a follow up study involving residents from multiple high-rise buildings.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36528232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Quantification of the Light Subunit of Neurofilament Protein in Cerebrospinal Fluid of Huntington's Disease Patients. 亨廷顿舞蹈病患者脑脊液中神经丝蛋白轻亚基的定量分析。
PLoS currents Pub Date : 2018-08-31 DOI: 10.1371/currents.hd.280c8f9f7d9fa4f7f0c883d9f8e807da
Natalia Szejko, Carmen Picón, Juan García-Caldentey, Justo Garcia de Yebenes, Jose Carlos Alvarez-Cermeño, Luisa Maria Villar, José Luis López-Sendón Moreno
{"title":"Quantification of the Light Subunit of Neurofilament Protein in Cerebrospinal Fluid of Huntington's Disease Patients.","authors":"Natalia Szejko,&nbsp;Carmen Picón,&nbsp;Juan García-Caldentey,&nbsp;Justo Garcia de Yebenes,&nbsp;Jose Carlos Alvarez-Cermeño,&nbsp;Luisa Maria Villar,&nbsp;José Luis López-Sendón Moreno","doi":"10.1371/currents.hd.280c8f9f7d9fa4f7f0c883d9f8e807da","DOIUrl":"https://doi.org/10.1371/currents.hd.280c8f9f7d9fa4f7f0c883d9f8e807da","url":null,"abstract":"<p><p> Neurofilament light proteins (NFL) are a structural element of the neuronal cytoskeleton and are released with neuronal damage. Its levels are increased in cerebrospinal fluid (CSF) in the setting of neurodegenerative diseases. We investigated the CSF-NFL levels of Huntington´s disease (HD) patients (participating in a clinical trial SAT-HD) as well as of premanifest carriers and compared their results with a sample of healthy controls and correlated CSF-NFL levels with demographic and clinical variables (baseline demographic characteristics and HD measures of disease severity). CSF levels were significantly higher in all HD subjects [5014.4 (1557.3) ng/l] and pre-manifest carriers [1050 (212.13) ng/l as compared to controls [331.4 (200.2) ng/l] (p<0.00) and were correlated with age (correlation coefficient -0.37, p<0.01) and CAG triplet number (0,51, p<0.05) in the subset of HD patients. NFL levels were not correlated with age in the control group. We did not find any correlation with the remaining variables. These results indicate, as in previous studies, that CSF-NFL levels are a marker of neuronal damage in HD. It seems to be a highly sensitive, but non-specific marker of axonal damage. One of the limitations of our study is a very small number of patients in pre-symptomatic group and lack of individuals with very advanced HD. Further investigations should focus on study of CSF-NFL levels in advanced patients, tracking prospectively CSF-NFL levels and analysing its correlation with the clinical course and usefulness to monitor disease progression, validation and quantification of NFL levels in more accessible biofluids.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36528233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Earthquakes to Floods: A Scoping Review of Health-related Disaster Research in Low- and Middle-income Countries. 地震到洪水:低收入和中等收入国家与健康有关的灾害研究的范围审查。
PLoS currents Pub Date : 2018-08-30 DOI: 10.1371/currents.dis.57d98a902a326361d88d54521e68b016
Catherine M Tansey, John Pringle, Anushree Davé, Renaud Boulanger, Matthew Hunt
{"title":"Earthquakes to Floods: A Scoping Review of Health-related Disaster Research in Low- and Middle-income Countries.","authors":"Catherine M Tansey, John Pringle, Anushree Davé, Renaud Boulanger, Matthew Hunt","doi":"10.1371/currents.dis.57d98a902a326361d88d54521e68b016","DOIUrl":"10.1371/currents.dis.57d98a902a326361d88d54521e68b016","url":null,"abstract":"<p><strong>Introduction: </strong>Health-related disaster research is a relatively small; but growing field of inquiry.  A better understanding of the scope and scale of health-related disaster research that has occurred in low- and middle-income countries (LMICs) would be useful to funders, researchers, humanitarian aid organizations, and governments as they strive to identify gaps, disparities, trends, and needs of populations affected by disasters.</p><p><strong>Methodology: </strong>We performed a scoping review using the process outlined by Arksey & O'Malley to assess the characteristics of peer-reviewed publications of empirical health-related disaster research conducted in LMICs and published in the years 2003-2012.</p><p><strong>Results: </strong>Five hundred and eighty-two relevant publications were identified.  Earthquakes were by far the most commonly researched events (62% of articles) in the review's timeframe.  More articles were published about disasters in China & South Asia/South East Asia than all other regions.  Just over half of the articles (51%) were published by research teams in which all the authors' primary listed affiliations were with an institution located in the same country where the research was conducted.  Most of the articles were classified as either mental health, neurology and stress physiology (35%) or as traumatology, wounds and surgery (19%).  In just over half of the articles (54%), data collection was initiated within 3 months of the disaster, and in 13% research was initiated between 3 and 6 months following the disaster.  The articles in our review were published in 282 different journals.</p><p><strong>Discussion: </strong>The high number of publications studying consequences of an earthquake may not be surprising, given that earthquakes are devastating sudden onset events in LMICs.  Researchers study topics that require immediate attention following a disaster, such as trauma surgery, as well as health problems that manifest later, such as post-traumatic stress disorder.  One neglected area of study during the review's timeframe was the impact of disasters on non-communicable and chronic diseases (excluding mental health), and the management of these conditions in the aftermath of disasters. Strengthening disaster research capacity is critical for fostering robust research in the aftermath of disasters, a particular need in LMICs.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36525026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Information Circulation in times of Ebola: Twitter and the Sexual Transmission of Ebola by Survivors. 埃博拉时期的信息传播:推特与幸存者的埃博拉性传播。
PLoS currents Pub Date : 2018-08-28 DOI: 10.1371/currents.outbreaks.4e35a9446b89c1b46f8308099840d48f
Celine Morin, Ida Bost, Arnaud Mercier, Jean-Pierre Dozon, Laetitia Atlani-Duault
{"title":"Information Circulation in times of Ebola: Twitter and the Sexual Transmission of Ebola by Survivors.","authors":"Celine Morin, Ida Bost, Arnaud Mercier, Jean-Pierre Dozon, Laetitia Atlani-Duault","doi":"10.1371/currents.outbreaks.4e35a9446b89c1b46f8308099840d48f","DOIUrl":"10.1371/currents.outbreaks.4e35a9446b89c1b46f8308099840d48f","url":null,"abstract":"<p><strong>Introduction: </strong>The 2013-2015 outbreak of Ebola was by far the largest to date, affecting Guinea, Liberia, Sierra Leone, and secondarily, Nigeria, Senegal and the United States. Such an event raises questions about the circulation of health information across social networks. This article presents an analysis of tweets concerning a specific theme: the sexual transmission of the virus by survivors, at a time when there was a great uncertainty about the duration and even the possibility of such transmission.</p><p><strong>Methods: </strong>This article combines quantitative and qualitative analysis. From a sample of 50,000 tweets containing the words \"Ebola\" in French and English, posted between March 15 and November 8, 2014, we created a graphic representation of the number of tweets over time, and identified two peaks: the first between July 27 and August 16, 2014 (633 tweets) and the second between September 28 and November 8, 2014 (2,577 tweets). This sample was divided into two parts, and every accessible publication was analyzed and coded according to the authors' objectives, feelings expressed and/or publication type.</p><p><strong>Results: </strong>While the results confirm the significant role played by mainstream media in disseminating information, media did not create the debate around the sexual transmission of Ebola and Twitter does not fully reflect mainstream media contents. Social media rather work like a \"filter\": in the case of Ebola, Twitter preceded and amplified the debate with focusing more than the mainstream media on the sexual transmission, as expressed in jokes, questions and criticism.</p><p><strong>Discussion: </strong>Online debates can of course feed on journalistic or official information, but they also show great autonomy, tinged with emotions or criticisms. Although numerous studies have shown how this can lead to rumors and disinformation, our research suggests that this relative autonomy makes it possible for Twitter users to bring into the public sphere some types of information that have not been widely addressed. Our results encourage further research to understand how this \"filter\" works during health crises, with the potential to help public health authorities to adjust official communications accordingly. Without a doubt, the health authorities would be well advised to put in place a special watch on the comments circulating on social media (in addition to that used by the health monitoring agencies).</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36525029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploratory Profiling of Urine MicroRNAs in the dy2J/dy2J Mouse Model of LAMA2-CMD: Relation to Disease Progression. LAMA2-CMD小鼠dy2J/dy2J模型中尿液微rna的探索性分析:与疾病进展的关系
PLoS currents Pub Date : 2018-08-27 DOI: 10.1371/currents.md.d0c203c018bc024f2f4c9791ecb05f88
Bernardo Moreira Soares Oliveira, Kinga I Gawlik, Madeleine Durbeej, Johan Holmberg
{"title":"Exploratory Profiling of Urine MicroRNAs in the <i>dy<sup>2J</sup>/dy<sup>2J</sup></i> Mouse Model of LAMA2-CMD: Relation to Disease Progression.","authors":"Bernardo Moreira Soares Oliveira,&nbsp;Kinga I Gawlik,&nbsp;Madeleine Durbeej,&nbsp;Johan Holmberg","doi":"10.1371/currents.md.d0c203c018bc024f2f4c9791ecb05f88","DOIUrl":"https://doi.org/10.1371/currents.md.d0c203c018bc024f2f4c9791ecb05f88","url":null,"abstract":"<p><p>Circulating microRNAs (miRNAs) are being considered as non-invasive biomarkers for disease progression and clinical trials. Congenital muscular dystrophy with deficiency of laminin α2 chain (LAMA2-CMD) is a very severe form of muscular dystrophy, for which no treatment is available. In order to identify LAMA2-CMD biomarkers we have profiled miRNAs in urine from the <i>dy<sup>2J</sup></i> /<i>dy<sup>2J</sup></i> mouse model of LAMA2-CMD at three distinct time points (representing asymptomatic, initial and established disease). We demonstrate that unique groups of miRNAs are differentially expressed at each time point. We suggest that urine miRNAs can be sensitive biomarkers for different stages of LAMA2-CMD.</p>","PeriodicalId":74464,"journal":{"name":"PLoS currents","volume":"10 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36666428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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