{"title":"A Window into Evergreen 2021 from the Next Generation of Phage Researchers.","authors":"Yuval Mulla, Kyle Enriquez, Jarin Taslem Mourosi, Katharine Muscat, Michael Shamash","doi":"10.1089/phage.2021.29019.eve","DOIUrl":"10.1089/phage.2021.29019.eve","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 3","pages":"100-103"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041497/pdf/phage.2021.29019.eve.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33486075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Being Swamped with Teaching to China and Back….","authors":"Martha R J Clokie","doi":"10.1089/phage.2021.29018.edi","DOIUrl":"https://doi.org/10.1089/phage.2021.29018.edi","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"67-68"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041495/pdf/phage.2021.29018.edi.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacteriophage to the Future: Insight from the Third Bacteriophage Therapy Summit.","authors":"Jonathan D Grinstein","doi":"10.1089/phage.2021.29014.jdg","DOIUrl":"https://doi.org/10.1089/phage.2021.29014.jdg","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"75-76"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041491/pdf/phage.2021.29014.jdg.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaonan Zhao, Qing Zhang, Thomas Sicheritz-Pontén, Yuqing Liu, Martha R J Clokie
{"title":"inPhocus: Perspectives of the Application of Bacteriophages in Poultry and Aquaculture Industries Based on Varms in China.","authors":"Xiaonan Zhao, Qing Zhang, Thomas Sicheritz-Pontén, Yuqing Liu, Martha R J Clokie","doi":"10.1089/phage.2021.29016.xzh","DOIUrl":"https://doi.org/10.1089/phage.2021.29016.xzh","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041493/pdf/phage.2021.29016.xzh.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Interview with Adam Ostrowski, PhD, of Cellexus.","authors":"Adam Ostrowski","doi":"10.1089/phage.2021.29017.aos","DOIUrl":"https://doi.org/10.1089/phage.2021.29017.aos","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041494/pdf/phage.2021.29017.aos.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Call for Special Issue Papers:</i> Phage Informatics and AI: Deadline for Manuscript Submission: September 30, 2021.","authors":"Martha R J Clokie","doi":"10.1089/phage.2021.29011.cfp2","DOIUrl":"https://doi.org/10.1089/phage.2021.29011.cfp2","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041488/pdf/phage.2021.29011.cfp2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen Fong, Catherine W Y Wong, Siyun Wang, Pascal Delaquis
{"title":"How Broad Is Enough: The Host Range of Bacteriophages and Its Impact on the Agri-Food Sector.","authors":"Karen Fong, Catherine W Y Wong, Siyun Wang, Pascal Delaquis","doi":"10.1089/phage.2020.0036","DOIUrl":"10.1089/phage.2020.0036","url":null,"abstract":"<p><p>Novel bacteriophages (phages) possessing a broad host range are consistently and routinely reported, yet there is presently no consensus on the definition of \"broad host range.\" As phages are increasingly being used in the development of methods for the detection and biocontrol of human pathogens, it is important to address the limitations associated with the host range. For instance, unanticipated host range breadth may result in the detection of nonpathogenic targets, thereby increasing the false-positive rate. Moreover, a broad host range is generally favored in biocontrol applications despite the risk of undesirable ancillary effects against nontarget species. Here, we discuss the research progress, applications, and implications of broad host range phages with a focus on tailed broad host range phages infecting human pathogens of concern in the Agri-Food sector.</p>","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 2","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/eb/phage.2020.0036.PMC9041489.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33477222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bailey M Pehde, Devon Niewohner, Faithe E Keomanivong, Michael D Carruthers
{"title":"Genome Sequence and Characterization of <i>Acinetobacter</i> Phage DMU1.","authors":"Bailey M Pehde, Devon Niewohner, Faithe E Keomanivong, Michael D Carruthers","doi":"10.1089/phage.2020.0043","DOIUrl":"https://doi.org/10.1089/phage.2020.0043","url":null,"abstract":"<p><p><b><i>Background:</i></b> There has been a recent resurgence of research on the characterization of <i>Acinetobacter</i> phage for therapeutic use due to the morbidity and mortality associated with treatment failures in cases of multidrug-resistant <i>Acinetobacter baumannii</i> infections. <b><i>Materials and Methods:</i></b> A bacteriophage isolated from activated sludge that targets <i>A. baumannii</i> ATCC19606 was characterized by electron microscopy, genome sequencing, comparative genomics, and a host range analysis. <b><i>Results:</i></b> The morphology of <i>Acinetobacter</i> phage DMU1 resembles phages in <i>Siphoviridae</i>. Comparative genomic and phylogenetic analyses reveal that DMU1 is a siphophage and is most closely related to <i>Acinetobacter</i> phage SH-Ab 15497. Out of the strains tested, DMU1 was found to only infect <i>A. baumannii</i> strains ATCC19606 and ATCC17978. <b><i>Conclusion:</i></b> <i>Acinetobacter</i> phage DMU1 belongs to the <i>Siphoviridae</i> family and is most closely related to <i>Acinetobacter</i> phage SH-Ab 15497. Small-scale host-range analysis of DMU1 indicates a host range that is likely limited to specific <i>A. baumannii</i> strains.</p>","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 1","pages":"50-56"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041440/pdf/phage.2020.0043.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33478037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Call for Special Issue Papers:</i> Phage Informatics and AI: Deadline for Manuscript Submission: August 31, 2021.","authors":"Martha R J Clokie","doi":"10.1089/phage.2021.29011.cfp","DOIUrl":"https://doi.org/10.1089/phage.2021.29011.cfp","url":null,"abstract":"","PeriodicalId":74428,"journal":{"name":"PHAGE (New Rochelle, N.Y.)","volume":"2 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041482/pdf/phage.2021.29011.cfp.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33478039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}