Open research Africa最新文献

{"title":"Addressing supply side constraints for digital work creation: A Concurrent Embedded Mixed Method Study in Kenya.","authors":"Kellen Kiambati, Ehud Gachugu, Anne Kariuki","doi":"10.12688/openresafrica.16307.2","DOIUrl":"10.12688/openresafrica.16307.2","url":null,"abstract":"<p><strong>Background: </strong>This paper addresses a pathway for addressing high unemployment among educated and skilled youth. The supply-side constraints limiting participation in dignified digital work remain underexplored. The aim was to examine how access to infrastructure, training and mentorship, and awareness creation influence engagement in digital work, and how demographic factors moderate these relationships.</p><p><strong>Methods: </strong>A mixed-methods concurrent design was used, combining quantitative data from a cross-sectional survey with qualitative insights gathered through focus group discussions (FGDs) and key informant interviews (KIIs).</p><p><strong>Results: </strong>Findings indicate variations in awareness of digital work, training and mentorship access, infrastructure access, and engagement across all demographic categories. Gender showed a negative correlation with infrastructure access and awareness but did not significantly relate to training and mentorship or engagement. Region, setting, age, education, and occupation all significantly correlated with digital work engagement and access levels. Moderation analysis revealed that demographic factors except gender and occupation strengthened the relationship between infrastructure access and engagement in digital work. Only regional diversity enhanced the relationship between training/mentorship and engagement, indicating generally equitable access across other demographic groups. Awareness levels and engagement were strengthened by region, setting, age, occupation, and education, but not by gender, demonstrating balanced gender influence. Overall, training and mentorship programs exhibited the most balanced implementation across demographics, while gender mainstreaming efforts appear to be yielding positive outcomes.</p><p><strong>Conclusions: </strong>The study found that work initiatives must integrate demographic considerations into the design of infrastructure, training, mentorship, and awareness programs. It make contribution by providing new evidence to guide policymakers in developing targeted interventions that expand dignified digital work opportunities as a strategy for reducing unemployment.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"9 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Perceptions and Acceptability of Genetically Modified Mosquitoes for Malaria Control in Mali, 2025.","authors":"Samba Diarra, Abou Sogodogo, Sarah Hartley, Seydou Doumbia","doi":"10.12688/openresafrica.16627.1","DOIUrl":"10.12688/openresafrica.16627.1","url":null,"abstract":"<p><strong>Introduction: </strong>Malaria remains a major public health issue in sub-Saharan Africa, especially in Mali. Despite the promising prospects of genetically modified mosquitoes (GMMs), their use raises several concerns. Community engagement is essential to the success of this tool. We assessed the Malian population's knowledge and perception of the risks associated with this technology.</p><p><strong>Methods: </strong>The study was conducted in rural areas in the Koulikoro region and Bamako (urban). The survey included 874 heads of household. The statistical analysis was done on R 4.3.0. Univariable and multivariable logistic regression were performed to identify key factors associated with the risk perceptions of GMMs. The study was approved by the ethics committee of the University of Sciences, Techniques, and Technologies of Bamako. Written informed consent was obtained from each participant.</p><p><strong>Results: </strong>The median age was 42 years (IQR: 33, 54), and 20.0% had no formal education. Only 18.2% (159/874) had previously heard information about GMMs, mainly by health workers (61.6%) and radio broadcasts (20.8%). The overall rate of risk perception regarding GMMs was 47.7% (417/874), with the most cited concern being the transmission of unknown diseases (95.9%). A high level of education was positively associated with higher risk perception. As well as being unaware of GMMs, doubts about the efficacy and safety of GMMs. The acceptability rate of GMMs was 77%, conditional on assurances that technology would not cause harmful effects and would first be tested in a controlled, restricted environment before being deployed on a large scale.</p><p><strong>Conclusion: </strong>Robust community engagement is essential for both research and real-world implementation of GMMs. A Thorough understanding of the conditions related to acceptance of this technology offers a strategic pathway for researchers and policymakers to design GMM that is socially responsive and contextually appropriate.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"9 ","pages":"30"},"PeriodicalIF":0.0,"publicationDate":"2026-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13310356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond VAR2CSA: redefining the antigenic landscape of placental malaria vaccines.","authors":"Lucy Mwai, Purity Gacheri Limbua, Jesse Gitaka, Bernard N Kanoi","doi":"10.12688/openresafrica.16523.1","DOIUrl":"10.12688/openresafrica.16523.1","url":null,"abstract":"<p><strong>Background: </strong>Placental malaria (PM) remains a leading driver of maternal and neonatal mortality, largely attributed to the sequestration of <i>Plasmodium falciparum</i>-infected red blood cells in the placenta. For decades, PM vaccine development has singularly focused on VAR2CSA, the immunodominant variant surface antigen. However, extreme polymorphism, limited cross-strain protection, and the structural complexity of VAR2CSA have hindered the development of a highly efficacious PM vaccine, necessitating a paradigm shift.</p><p><strong>Methods: </strong>This review examines existing literature to map potential vaccine antigens implicated in placental malaria ,and outlines a comprehensive vaccine development pipeline. It synthesizes emerging data on antigen expression profiles, immunogenicity, and mechanistic roles in placental pathogenesis. In addition, it highlights both key placental and blood-stage antigens expressed during pregnancy and reviews identification and testing strategies to guide rational PM vaccine design.</p><p><strong>Results: </strong>This Review maps the expanding antigenic landscape of PM beyond VAR2CSA, identifying non-canonical surface and exported proteins, including SURFINs, PHISTs, PfRON3, and <i>Pf</i>CSA-L, as critical targets that may circumvent current bottlenecks. The findings highlight the relevance of these antigens in placental malaria pathogenesis and their potential as alternative or complementary vaccine candidates.</p><p><strong>Conclusions: </strong>Furthermore, we propose an integrated framework for rational vaccine design that couples high-throughput antigen discovery and structural immunogen engineering with multivalent formulation strategies. By bridging the gap between molecular parasitology and translational immunology, this roadmap offers a strategic path toward a broadly protective placental malaria (PM) vaccine.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"9 ","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Youth Employment Preferences in Rwanda and Sierra Leone: A Constrained Comparative Secondary Analysis.","authors":"Sixbert Sangwa, Enjamin Kagiraneza, Benilde Tieche Muberarugo, Kamuskay Kamara, Rebecca Sarah Jawara","doi":"10.12688/openresafrica.16530.1","DOIUrl":"https://doi.org/10.12688/openresafrica.16530.1","url":null,"abstract":"<p><strong>Background: </strong>Youth labour markets across Sub-Saharan Africa combine high aspirations for secure wage work with entrenched informality and underemployment.</p><p><strong>Aim: </strong>This article clarifies how structural constraints shape stated employment preferences and entrepreneurial orientation among youth in Rwanda and Sierra Leone.</p><p><strong>Design: </strong>A constrained comparative secondary analysis drew on Afrobarometer Round 9 microdata for Sierra Leone and triangulated these findings with nationally reported labour-market and policy indicators for Rwanda. Public microdata for Rwanda were unavailable, so a bounded-evidence strategy transparently distinguishes verifiable survey statistics from document-based context.</p><p><strong>Findings: </strong>Sierra Leonean youth express a cautious economic outlook-fewer than half expect improvement within a year-yet most endorse redistributive growth and demand stronger gender equity in job access. Preference for self-employment appears necessity-driven where institutional trust and public-goods provision remain moderate, rather than an indicator of opportunity entrepreneurship. Rwanda's reported labour-absorption pressure and pervasive informality reinforce this reading, suggesting that education-fuelled aspiration gaps widen when formal job creation lags.</p><p><strong>Contribution: </strong>The study advances an \"institutionally conditioned planned-behaviour\" framework that integrates the Theory of Planned Behaviour with opportunity-structure theory and human-capital expectations. Methodologically, it demonstrates how rigorous comparative inference can be maintained through explicit verification protocols when evidence access is asymmetric, and it outlines a reproducible pathway for symmetric modelling once Rwandan microdata become publicly available.</p><p><strong>Practical implications: </strong>Policies that promote youth entrepreneurship without parallel investment in inclusive growth, reliable public goods, and transparent digital governance risk shifting systemic labour-market failure onto young people rather than resolving it.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"9 ","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13191316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Lineage Property to Individual Property: Dynamics of Land Management in the Villages of Nasso and Dindéresso, Hauts-Bassins, Burkina Faso.","authors":"Abdoulaye Sawadogo","doi":"10.12688/openresafrica.16420.1","DOIUrl":"10.12688/openresafrica.16420.1","url":null,"abstract":"<p><strong>Background: </strong>This article analyses the dynamics of relations between communities and land resources in a context of scarcity resulting from land speculation. Faced with this reality, the changes brought about by social dynamics in the land sector have ultimately led to the introduction of new forms of land ownership in the villages of Nasso and Dindéresso in Burkina Faso. This issue is a corollary of spatial expansion following urban sprawl due to population growth and speculation around peri-urban land. With increased interest in peri-urban land, traditional management norms are eroding, giving way to more modern management norms that offer more power to individuals.</p><p><strong>Methods: </strong>This research is based on a qualitative approach using data from documentary reviews, semi-structured interviews with community and administrative actors, and direct observation. This approach has made it possible to analyse land management through the prism of public policies and internal community dynamics. Property rights theory has been used to examine this issue.The combination of methodological and theoretical approaches has yielded illustrative results.</p><p><strong>Results: </strong>These results reveal the nature and challenges of the fragmentation of land ownership rights within communities. To this end, it appears that land dynamics have had a significant impact on forms of intra-community land ownership, leading to the individualisation of land rights following the advent of land commodification.</p><p><strong>Conclusions: </strong>In conclusion, it appears that land is a cross-cutting issue that impacts all spheres of society. Hence the multiple and multifaceted challenges in terms of land governance and the consolidation of social cohesion.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"9 ","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13032100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy Use and Economic Performance Nexus in Sub-Saharan Africa: A Multivariate Analysis.","authors":"Mfonobong Effiong, Manoj Panicker","doi":"10.12688/openresafrica.15788.2","DOIUrl":"10.12688/openresafrica.15788.2","url":null,"abstract":"<p><p>Background Sub-Saharan Africa's energy landscape is complex, with various factors influencing economic growth and development. Understanding the interplay between energy use, economic performance, and natural resources is crucial for sustainable development. This study investigates the relationships between energy use, GDP, low-carbon energy output, natural resources, and economic performance in Sub-Saharan Africa. Methods This study employed advanced econometric techniques, including generalized linear models, generalized method of moments, and vector error correction models. Data from the Global Economy Database spanning 1990-2024 were analyzed to uncover relationships between energy use, GDP, low-carbon energy output, and natural resources. Results The analysis showed significant variations in low-carbon energy output (mean = 68.86 units), natural gas profit margin (mean = $0.10), and oil operating surplus (mean = $3.50). The GLM and GMM estimates revealed significant relationships between energy use and GDP (7.419%), low-carbon energy output (6.079%), natural gas profit margin (67.377%), and oil operating surplus (4.575%). The analysis revealed significant variability in low-carbon energy production, natural gas profitability, and oil operating surpluses. Statistical models showed strong correlations between energy consumption and GDP growth, as well as low-carbon energy output and natural resource utilization. Conclusions The study finds complex dynamics between the variables, with both short-term and long-term effects. The research contributes to existing knowledge by providing empirical evidence of the relationships between energy use, GDP, low-carbon energy output, natural resources, and economic performance, offering valuable insights for policymakers and stakeholders seeking to promote sustainable energy use and economic development in Sub-Saharan Africa. This research provides novel insights into the intricate relationships governing Sub-Saharan Africa's energy sector and economic development. The findings offer valuable guidance for policymakers and stakeholders seeking to promote sustainable energy use, economic growth, and environmental stewardship in the region.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"8 ","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13032103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potentiation of the antimycobacterial activity of bedaquiline, clofazimine, and doxycycline against <i>Mycobacterium smegmatis</i> by several natural product-based compounds is putatively via efflux inhibition.","authors":"Robi Chacha, Caroline Maina, Edwin Murungi, Eric Guantai, Mathew P Ngugi, Ephantus Ndirangu, James Mugo, Sospeter Ngoci Njeru, Elizabeth Kigondu","doi":"10.12688/openresafrica.16071.2","DOIUrl":"10.12688/openresafrica.16071.2","url":null,"abstract":"<p><p>Background <i>Mycobacterium tuberculosis</i> ( <i>Mtb</i>), the causative agent of tuberculosis (TB), is the leading cause of death due to a single infectious pathogen globally. The increasing prevalence of drug-resistant <i>Mtb</i> strains underscores the pressing need for the development of new antimycobacterial drugs with novel mechanisms of action. Targeting pathogen drug efflux, a key antimycobacterial drug resistance mechanism, is an attractive, viable strategy for the development of new TB therapeutics. Methods In this study, we utilised <i>Mycobacterium smegmatis</i> ( <i>Msm</i>), a non-pathogenic <i>Mtb</i> surrogate, to delineate the ability of natural-product based compounds to augment the efficacy of bedaquiline (BDQ), clofazimine (CFZ) and doxycycline (DOX), probably via efflux inhibition (EI). Literature reporting the plant sources of the known efflux inhibitors (EIs) reserpine (RES), berberine (BER) and piperine (PIP) was scoped and additional compounds, (+)-lyoniresinol-3-Alpha-O-Beta-D-glucopyranoside (LYO-3) and lyoniresinol (LYO), isolated from the same plant species were chosen for testing. <i>In vitro</i> screening of the selected compounds was performed using the two-dimensional (2-D) checkerboard assay in which each likely efflux disruptor was tested in combination with BDQ, CFZ and DOX against <i>Msm</i> and the effect of the combinations ascertained. Thereafter, compounds that exhibited probable EI activity were docked onto potential targets namely MSMEG_5187, a <i>Msm</i> homologue of <i>Mtb</i> Rv1258c efflux pump (EP) and MmpL5. Results Molecular docking revealed that the EIs avidly bound to the EPs with docking scores of <-7 kcal/mol while the checkerboard combination assays demonstrated strong synergistic interactions for BDQ plus BER, LYO-3 and LYO. Conclusion These results point to a probable disruption of the <i>Msm</i> efflux system by <i>Berberis species</i> derivatives.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"8 ","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2026-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional composition of <i>Zea mays L</i>: A comprehensive Review of Macronutrients, Micronutrients, and Bioactive Compounds.","authors":"Sandra Etumah Ifie, Reuben Samson Dangana, Dominic Swase, Michael Ben Okon, Wusa Makena, Mary Olaoluwa Agunloye, Chinyere Nneoma Ugwu, Josiah Eseoghene Ifie, Saidi Odoma, Abubaka Ibrahim Babangida, Patrick Maduabuchi Aja","doi":"10.12688/openresafrica.16056.2","DOIUrl":"10.12688/openresafrica.16056.2","url":null,"abstract":"<p><strong>Background: </strong>Maize ( <i>Zea mays L.</i>) is a significant cereal crop, which, due to its nutritious content, especially in terms of dietary energy and nutrients, is globally important. Its nutritive status does not just end with macronutrients, but it also encompasses nutrient status that promotes health-giving micronutrients and phytochemicals.</p><p><strong>Objective: </strong>This review aims to consolidate recent advancements in maize nutrient profiling and highlight current challenges in optimizing its nutritional potential across global food systems.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in PubMed, Scopus, and Google Scholar for peer-reviewed articles published between 2010 and 2024 in English. Search terms included \"Zea mays nutrition,\" \"maize macronutrients,\" \"maize micronutrient biofortification,\" and \"phytochemicals in maize\". Studies included both empirical and review papers reporting on maize nutritional quality, bioavailability, and impacts on human health.</p><p><strong>Results: </strong>Maize is composed primarily of carbohydrates, with starch as the dominant fraction, alongside moderate protein and low lipid content concentrated in the germ. Biofortified varieties, including Quality Protein Maize (QPM), provide enhanced levels of lysine, tryptophan, and provitamin A. Maize also supplies essential B vitamins and minerals such as iron, zinc, and magnesium; however, their bioavailability is reduced by antinutrients like phytates. In addition, maize is shown to be rich in phytochemicals, including ferulic acid, flavonoids, and carotenoids, which exhibit antioxidant and therapeutic properties.</p><p><strong>Conclusion: </strong>Maize is more than a staple food crop; it is an indispensable crop for global food and nutrition security. However, challenges such as low bioavailability due to antinutritional factors limit its full nutritional potential. Therefore, strengthening genetic and agronomic interventions to improve its nutritional quality is essential to address hidden hunger and enhance population health worldwide.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"8 ","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizational Structure, Performance Monitoring, and Academic Staff Performance in Selected Private Chartered Universities: A Qualitative Study.","authors":"Turyamureeba Silaji, Zulaihatu Lawal Bagiwa, Tukur Muhammad","doi":"10.12688/openresafrica.15891.4","DOIUrl":"10.12688/openresafrica.15891.4","url":null,"abstract":"<p><p>This qualitative study investigates how organizational structure and performance monitoring influence academic staff performance in selected private chartered universities in Western Uganda. Using a phenomenological design, the study explored the lived experiences and perceptions of 10 academic leaders, including deans and senior lecturers, across various faculties. Participants were purposively selected for their strategic roles in academic administration, with qualifications ranging from Master's degrees to PhDs in fields such as Education Management, Science Education, and Clinical Medicine. Data were collected through in-depth interviews and thematically analyzed. Findings revealed that highly centralized structures, lack of autonomy, and inconsistent monitoring mechanisms contribute to diminished staff morale and reduced teaching effectiveness. However, faculties led by deans with advanced academic qualifications and more inclusive leadership approaches demonstrated stronger performance cultures, improved staff engagement, and better alignment with institutional goals. The study highlights the critical role of academic leadership, structural clarity, and transparent performance monitoring in enhancing academic productivity. It recommends rethinking internal governance frameworks to foster participatory management and accountability within Uganda's private university sector.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"8 ","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12854204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Stimulation Therapy for older people with Dementia in Africa: A Scoping Review.","authors":"Stephen Ojiambo Wandera, Edward Duncan, Monica Maria Diaz, David Otundo Ayuku","doi":"10.12688/openresafrica.14092.4","DOIUrl":"10.12688/openresafrica.14092.4","url":null,"abstract":"<p><strong>Background: </strong>Cognitive Stimulation Therapy (CST) is a non-pharmacological intervention developed for dementia that is useful in Africa but has not been studied widely. We reviewed the existing evidence regarding CST among older people living with dementia in Africa.</p><p><strong>Methods: </strong>A systematic literature search on CST among older people with dementia in Africa from 2003-2021 was done in MEDLINE (PubMed), CINAHL (EBSCOhost), and PsycINFO. A narrative approach was taken to chart, synthesize and interpret the data using Microsoft Excel.</p><p><strong>Results: </strong>After removing duplicates using Endnote, a total of 122 studies were retained and screened first by title, then abstract, and finally by full text. Six articles matched the inclusion/exclusion criteria. CST has been adapted and piloted in two African countries (Nigeria and Tanzania). CST studies in Africa indicate improvements in clinical outcomes including cognition and quality of life. Although there are some barriers to overcome, CST may be applicable to an African context.</p><p><strong>Conclusions: </strong>CST is feasible, adaptable, and acceptable in the African countries it has been implemented in. Some cultural barriers, such as religious affiliation and respect for older people, should be overcome. Further research is needed to further evaluate the efficacy of CST in various African contexts.</p>","PeriodicalId":74358,"journal":{"name":"Open research Africa","volume":"6 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12859423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}