Obstetrics and gynecology research最新文献

{"title":"Knowledge and Practice of Gestational Diabetes Mellitus Management Guideline among the Nurses of Tertiary Hospitals in Capital Bangladesh","authors":"H. Khanom, B. Banu, Mir Rabiul Islam, K. Khanom, Sujana Haque Chowdhury, S. Hossain","doi":"10.26502/ogr080","DOIUrl":"https://doi.org/10.26502/ogr080","url":null,"abstract":"Background: Gestational Diabetes Mellitus (GDM) accounts for the majority of cases of diabetes compli-cating pregnancy. This study aimed to delineate the levels of knowledge and practice about GDM management among the nurses of Dhaka, Bangladesh. Method: This cross-sectional study was conducted among 427 nurses of three healthcare centers of Dhaka city. Data were collected by semi-structured questionnaire through face-to-face interview. All data were analyzed through descriptive and inferential statistical techniques. Knowledge and practice scores were categorized as poor (<Mean–1SD), average (Mean±1SD) and good (>Mean+1SD) by predefined scores. Result: In this present study, mean age of the respon-Obstet dents was found 27.8 ± 5.5, and level of knowledge (both basic and technical knowledge) was found to be average where basic knowledge was 66.3% and technical knowledge was 67%. Female nurses had better basic knowledge and practice regar-ding GDM, compared to their counterparts (p=0.002). There was a significant association with the respon-dent’s gender, level of education and workplace with the basic knowledge regarding GDM management. There was a significant association with the level of education and marital status of respondents with technical knowledge and regarding proper GDM management practice only monthly family income of respondent’s shows significant association. Conclusion: The results revealed that there is a gap of knowledge and practice about the management of GDM among nurses’ capital of Bangladesh. Capacity building training should conduct regularly for young graduate nurses so that they can apply knowledge properly in the practice area.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FLUSHING OF THE FOLLICLES IN OVUM PICK-UP PROCEDURES GIVES A BETTER CHANCE FOR PREGNANCY IN LOW OVARIAN RESERVE PATIENTS","authors":"S. Oral, A. Sismanoglu","doi":"10.26502/ogr0101","DOIUrl":"https://doi.org/10.26502/ogr0101","url":null,"abstract":"Background: This study aims compare the pregnancy and live birth rates between the oocytes retrieved without follicular flushing FF(-) in the oocyte pick-up (OPU) procedure performed in women with diminished ovarian reserve (DOR) and those retrieved by follicular flushing FF(+). Results: The study was conducted among patients diagnosed with DOR according to Bologna criteria and applied to the clinic for IVF between 2017-2020. A total of 358 infertile women with follicles three and below on the hCG day, between the ages of 21 and 42, without severe male factor, without uterine anomaly, without uterine surgery, and who did not undergo PGD were included in the study. Each follicle was aspirated once in the OPU procedure, and if a follicle was retrieved, it was moved to the other follicle. If the follicle could not be retrieved, the oocyte was tried to be retrieved by flushing a maximum of 3 times. The number of oocytes retrieved, clinical pregnancy rate, and live birth rate were compared. Since all the oocytes retrieved in 143 patients were retrieved directly without the need for FF, it was named FF(-) group. Since at least one oocyte of the remaining 215 patients was retrieved by performing FF, it was named FF(+) group. Since some of the oocytes retrieved from 112 patients in the FF(+) group were retrieved with FF and some without FF, they were excluded from the study, and the remaining 103 cases formed the FF(+) group a total of 246 patients were compared. The mean number of MII oocytes ,the pregnancy rates , rates of live births and the abortion rates between two groups did not show any statistical difference. Conclusion: FF applied during oocyte retrieval in DOR did not positively affect the number of retrieved oocytes, clinical pregnancy, and live birth rates even doing this may decrease the pregnancy rate because of the probable low quality egg but we should not forget that if we did not do flushing after once we aspirated the follicle we would not be able to obtain any pregnancy at all in this patients.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69351850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status of Vitamin D in Women with Uterine Fibroid and Impact of Vitamin D Supplementation","authors":"Shiuly Chowdhury, S. Selim, M. Islam, Shuva Shrestha","doi":"10.26502/ogr0105","DOIUrl":"https://doi.org/10.26502/ogr0105","url":null,"abstract":"Background: Uterine fibroids, also known as leiomyomas, are benign smooth muscle tumors of the uterus. The exact cause of uterine fibroids is indistinct. However, fibroids appear to be partly determined by hormone levels. There is a high prevalence of Vitamin D deficiency for uterine fibroids. Vitamin D from food or from skin synthesis by sunshine becomes biologically inactive. It is activated by two protein enzyme hydroxylation steps. The first in the liver and the second in the kidney. As Vitamin D can be synthesized, it is considered a prohormone. Vitamin D is taken to the liver where it is transformed into 25[OH] D. Objective: The objective of this study was to determine the impact of Vitamin D supplementation in women with fibroids uterus. Methods: This interventional study was conducted in the department of obstetrics & gynecology, BSMMU, Dhaka, Bangladesh. A purposive sampling method was done. A total of 95 patients diagnosed as uterine fibroids with Vitamin D deficiency were included in the study. BMI was measured and the size of the fibroid was determined by ultrasonography and serum Vitamin D level was estimated. Vitamin D was supplemented to the participants. Then repeat ultrasonography and serum Vitamin D level were done after 3 months, to the assessment of vitamin impact. Regression of the size of the fibroid was done. Results: The mean age was 37.31±7.10 years. The majority of the participants were housewives 67.4%. Mean Vitamin D was 21.71±7.32, BMI 27.96±4.72. At the initial stage, among total study population in 11.6% (n=11), 47.4% (n=45) and 41.0% (n=39) patients we found <2.5cm(Small), 2.5-4.9cm (Medium) and (≥5cm (Large) sized fibroids respectively. The mean size of fibroids in a total of 95 patients was 4.99 ± 2.59 and after Vitamin D supplementation it had been reduced to 4.77±3.04. Conclusion: Supplementation with Vitamin D in women with fibroid uterus regress the fibroid size and it is more effective in smaller fibroid sizes. In this study, the size of uterine fibroid was reduced after supplementation of Vitamin D among the patients. It was significant (p<0.05) of fibroid uterus size changed after the Vitamin D supplement.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69351905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Models for Emergency Department Triage using Machine Learning: A Review","authors":"Fei Gao, B. Boukebous, Pozzar Mario, Alaoui Enora, Sano Batourou, Sahar Bayat-Makoei","doi":"10.26502/ogr082","DOIUrl":"https://doi.org/10.26502/ogr082","url":null,"abstract":"Predictive Models for Emergency Department Triage using Machine Learning: A Review. Obstetrics Abstract Background: Recently, many research groups have tried to develop emergency department triage decision support systems based on big volumes of historical clinical data to differentiate and prioritize patients. Machine learning models might improve the predictive capacity of emergency department triage systems. The aim of this review was to assess the performance of recently described machine learning models for patient triage in emergency departments, and to identify future challenges. Methods: Four databases (ScienceDirect, PubMed, Google Scholar and Springer) were searched using key words identified in the research questions. To focus on the latest studies on the subject, the most cited papers between 2018 and October 2021 were selected. Only works with hospital admission and critical illness as outcomes were included in the analysis. Results: (hospital admission and critical illness) and developed 55 predictive models. Random Forest and Logistic Regression were the most commonly used prediction algorithms, and the receiver operating characteristic-area under the curve (ROC-AUC) the most frequently used metric to assess the algorithm prediction performance. Random Forest and Logistic Regression were the most discriminant models according to the selected studies. Conclusions: Machine learning-based triage systems could improve decision-making in emergency departments, thus leading to better patients’ outcomes. However, there is still scope for improvement concerning the prediction performance and explicability of ML models.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Effects of Amniotomy and Spontaneous Rupture of Membrane on Duration of Labor in Primigravida at Term Pregnancy","authors":"Tanveer Shafqat, Laila Zeb, Sumaira Yasmin","doi":"10.26502/ogr090","DOIUrl":"https://doi.org/10.26502/ogr090","url":null,"abstract":"Purpose: Early amniotomy is one of the most important procedures for improving labor progress and preventing dystocia in pregnant women. The study compared the effects of amniotomy and spontaneous rupture of membrane (in early labor in primigravida at term) on the duration of labor. Methodology: Randomized Controlled Trial was conducted at the Department of Obstetrics and Gynecology MTI, Lady Reading Hospital, Peshawar, Pakistan. A total of 80 pregnant women with a single cephalic fetus in early labor were included in the study. Group A included 40 women in whom amniotomy was performed; while group B had 40 women who had spontaneous rupture of membranes. Duration of labor was noted in both groups. Results: The average age of Group A females in labor was 27.17 years and 26.2 years in group B. Gestational age and weight of mothers averaged 38 weeks and 67 kg in both groups respectively. The duration of labor was 5.7 hours in Group A and was prolonged at 7.1 hours in Group B. The mean duration of labor was 5.7 hours in Group A and 7.15 hours in Group B (P-value = 0.01). Regardless of the age of the mothers in either group, the mean duration of labour was 5.7 hours (18- 30 years) and 5.5 hours (above 30 years) in Group A, compared to Group B, 7.1 hours (18-30 years) and 7.0 hours above 30 years). Significant differences (P- value: 0.01) existed between each age group, gestational age, and weights in groups A (amniotomy) and B (spontaneous rupture of membranes) concerning the duration of labor. Conclusion: Artificially rupturing the membranes during active labor in primigravida reduces the length of labor considerably.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NSS-Bridge Device for Post-Cesarean Delivery Analgesia: A Randomized Controlled Trial.","authors":"Grace Lim, Emma Nowakowski, Kelsea R LaSorda, Valeria Altamirano, Madison Morgan, Mutasim Makeen, Stacy Beck, Elizabeth Krans, Jacques E Chelly","doi":"10.26502/ogr094","DOIUrl":"10.26502/ogr094","url":null,"abstract":"<p><strong>Introduction: </strong>Percutaneous auricular nerve stimulation has been used for the treatment of symptoms associated with opioid withdrawal, including abdominal pain, nausea, and general discomfort. However, its potential utility for pain management and opioid minimization after surgery has not been investigated. The purpose of this study was to test the feasibility and acceptability of a trial protocol designed to assess the effectiveness of the NSS2-Bridge device as a non-pharmacologic alternative to opioids after cesarean delivery.</p><p><strong>Methods: </strong>In a randomized control design, healthy women receiving cesarean delivery were randomized to receive the active device, placebo device, or no device. Devices were placed on the ear following cesarean delivery and left in place for 5 days. Feasibility and acceptability of the device was assessed by patient reports of device tolerability (rated on a 100mm visual analog scale where 0 is not tolerable at all and 100 is the most tolerable) as well as qualitative reporting. Additional outcomes assessed included proportion of patients not using opioids in hospital, as well as pain at rest, pain with movement, and total opioid consumption in the hospital and for the first 5 days after surgery.</p><p><strong>Results: </strong>There were 60 patients included in the final analysis. Device tolerability was rated highly, with an average daily score of >75 mm on the visual analog scale. The trial retention rate was 89.7% with most exclusions (42.9%) occurring due to unanticipated development of care complexity (e.g., hemorrhage and additional surgical procedures), with only 1 exclusion (14.3%) due to device discomfort. The active device group achieved the highest proportion of opioid-free hospitalizations (40%) compared to placebo (20%) and no device groups (30%). Pain at rest and with movement was similar between treatment groups.</p><p><strong>Conclusions: </strong>This trial protocol designed to test the efficacy of NSS2-Bridge device for post-cesarean pain management is feasible and acceptable. Larger proportions of patients not using opioids in the active device group justifies additional investigation on device effectiveness in pregnant and postpartum people at highest risk for pain.</p>","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"5 3","pages":"210-218"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581440/pdf/nihms-1839922.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40664781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Incidence of Placenta Previa among Women with Subsequent Pregnancy after Previous Cesarean Sections","authors":"R. -, Robina Zahoor, Hina Ameer Chughtai, Hania Zafar, Sadia Ilyas, Sohaib Mujahid, Muhammad Abu Bakar","doi":"10.26502/ogr086","DOIUrl":"https://doi.org/10.26502/ogr086","url":null,"abstract":"Background: Placenta previa is one of the leading causes of vaginal bleeding in second and third trimester of pregnancy. The risk of placenta previa is also higher among women with previous cesarean section. The purpose of our study was to determine the frequency of placenta previa among patients undergoing repeat cesarean section. Materials and Methods: This Cross-sectional study was conducted at the Department of Gynecology, Lahore General Hospital, Lahore. The calculated sample size was 240 cases recruited through non probability purposive sampling. All the patients underwent an obstetrical scan for the presence of placenta previa. The women who were detected with placenta previa were further enquired for the numbers of previous cesarean section. The data was collected on specifically designed proforma (attached). All the collected data was entered into SPSS version 10 and analyzed. The qualitative data like presence of placenta previa (yes or no) was presented as frequency and percentage. Results: There were 240 females included in the study with the mean age of 30.41 ± 5.47 years. The mean gestational age was 34.50±2.97 weeks. There were 233 (97.08%) females who did not develop placenta previa while 7 (2.92%) females had placenta previa. There was insignificant difference observed for frequency of placenta previa with age of females, parity and cesarean section (P>0.05). Conclusion: The incidence of placenta previa is found to be low in local population who had multiple cesarean section.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Anti Mullerian Hormone and Antral Follicular Count in Ovarian Reserve Testing","authors":"A. K, Partha Majumder S, S. R","doi":"10.26502/ogr088","DOIUrl":"https://doi.org/10.26502/ogr088","url":null,"abstract":"Background: Ovarian reserve defines a woman’s reproductive ability and the number and quality of oocytes she possesses. It is a complex clinical state dependent on age, genetics, and environmental issues. It can reflect women’s endocrine function and fertility which may gradually decrease with increasing age. Methods: This study was a cross-sectional study conducted at the out-patient department of Obstetrics and Gynae, in Enam Medical College Hospital, Savar and a local private hospital at Savar. The study was conducted during the period of July 2019-December 2019. The sample size for this study was 120. Result: The most respondent 44 (36.7%) were in between 35-40 years. The mean ± SD of BMI was 26.61 ± 1.96 and followed by duration of infertility (years) was 3.75 ± 1.64, total ovarian volume (ml) was 7.66 ± 1.32. Tubal factor was found in 27 (21.7%) cases and followed by male factor was in 24 (20%), PCOS was in 20 (16.7%), endometriosis was in 6 (5%), unexplained infertility was in 22 (18.3%). In low group AFC (mean ± SD) was 07.15 ± 4.82 where AMH (mean ± SD) was 6.66 ± 5.34 and followed by normal was 09.38 ± 3.59 and 9.48 ± 3.91and high was 15.45 ± 5.46 and 16.08 ± 5.23. There was no significance correlation found in these two predictors. Conclusion: AMH is considered as most reliable investigation for ovarian reserve testing. Serum AMH level has strong correlation with comparatively low cost Antral follicular count. Antral follicular count can be done in poor patients for ovarian reserve test.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and Facilitators for Physical Activity in Pregnancy and Post- Partum? Findings from a Qualitative Study to Inform the Design of an Intervention for Active Women","authors":"Murali K P Subramanian, P. V. der Graaf, L. Hayes, Rose I Dawson, Kunj Sachdeva, L. Azevedo","doi":"10.26502/ogr0102","DOIUrl":"https://doi.org/10.26502/ogr0102","url":null,"abstract":"Objectives: The benefits of physical activity during and after pregnancy are well established. However, activity levels decline substantially in both inactive and active women. There is limited information on the barriers and facilitators for physical activity participation in active women, which is vital for the development of tailored interventions. The primary aim of this study is to identify the barriers and facilitators for physical activity (PA) in already active women during pregnancy and postpartum. We also explore their views on, and requirements for, the development of an intervention to support maintenance of or increase in physical activity. Methods: Five focus groups, with a total of 19 participants, were conducted using a topic guide structured around the study objectives. Transcripts were analysed using a thematic analysis approach. Results: Twenty-two codes were generated and grouped into 8 themes: (1) cognizant of PA benefits, (2) sources of advice, (3) reasons to be active during pregnancy, (4) reasons for reducing PA levels during pregnancy, (5) barriers to PA during and after pregnancy, (6) facilitators of PA during and after pregnancy, (7) ideal PA intervention, and (8) evaluation support. Conclusion: Already active women show enthusiasm for continuing PA during and after pregnancy. However, factors such as pregnancy- related body changes, childcare and lack of targeted activities deter participation in PA. A new PA programme with social and group elements, including both familiar and new activities, and providing „satisfaction and fun‟ should be developed for previously active pregnant and postpartum women to help increase or maintain PA levels","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69351855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinicopathological Study: Expression of ER, PR and HER/2neu in Endometrial Carcinoma Published On: 20","authors":"Jasmeen Kaur, A. Suri, M. Kaur","doi":"10.26502/ogr077","DOIUrl":"https://doi.org/10.26502/ogr077","url":null,"abstract":"Endometrial carcinoma is a common invasive malignancy of the female genital tract. Investigation of endometrial immunomarkers involved in carcinogenesis may influence early detection and treatment, with direct impact on prognosis by increasing life expectancy. It can often be difficult to distinguish higher grade endometrioid carcinomas from serous carcinomas. Use of immunohistochemistry as an adjunct has been the subject of a number of recent studies. Aims and Objectives: To study the association of endometrial carcinoma with relation to age, parity and other presenting feature. To determine the association between the expression of ER, PR, and Her-2/neu and clinicopathological features of endometrial carcinoma patients. To correlate the endometrial histopathology with immunohistochemistry. Material and methods: The present study comprised of analysis of 50 cases of endometrial carcinoma received in the Department of Pathology, Government Medical College, Patiala from January 2018 to May 2020. Routine Haematoxylin and Eosin and on confirmed cases of endometrial carcinoma , IHC for ER, PR and HER-2/neu was performed. Results: Endometrioid carcinomas showed maximum incidence around the age of 65 with G1 tumours 56%, G2 12%, G3 18 % and non Endometrioid were mostly serous and clear representing Obstet Gynecol Res 2022; 5 (1): 041-053 DOI: 10.26502/ogr077 Obstetrics and Gynecology Research Vol. 5 No. 1– March 2022. 42 14% cases. The predominance of grade-I endometrial carcinoma was found in 56% followed by grade-II in 12% and grade-III in 18% cases. Statistical analysis showed that the degree of differentiation significantly correlated (very highly significant) significant) with histology (p value .000). Out of 50 cases of EMC, 32(64%) cases showed ER positivity. PR positivity was seen in 30(60%) cases and HER-2/neu immunehistochemical expression was positive in 11(22%) cases. Conclusion: A decrease of the hormonal receptors expression, ER and PR was observed in parallel with the decreased histological degree of differentiation, the lowest values occurring in the case of Endometrioid G3 carcinomas and were absent in NonEndometrioid carcinomas. This finding may be of a particular clinical importance because almost half of poorly differentiated endometrial carcinomas contain estrogen/progesterone receptors and they might benefit from a progesterone therapy. PR immuneexpression showed statistically significant association with parity, presenting symptom, type, and grade of EMC. Here by, making it an independent prognostic factor.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}