NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2022-9_4
N. Daudet, Magdalena Żak, T. Støle, Stephen Terry
{"title":"Genetic Manipulation of the Embryonic Chicken Inner Ear","authors":"N. Daudet, Magdalena Żak, T. Støle, Stephen Terry","doi":"10.1007/978-1-0716-2022-9_4","DOIUrl":"https://doi.org/10.1007/978-1-0716-2022-9_4","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51711420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2026-7_1
Max J. van Essen, S. Nayler, Elizabeth J. Apsley, John Jacob, Esther B. E. Becker
{"title":"Cerebellar Modelling Using Human Induced Pluripotent Stem","authors":"Max J. van Essen, S. Nayler, Elizabeth J. Apsley, John Jacob, Esther B. E. Becker","doi":"10.1007/978-1-0716-2026-7_1","DOIUrl":"https://doi.org/10.1007/978-1-0716-2026-7_1","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51711698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2083-0_15
Hyewon Kim, Yong-Ku Kim, H. Jeon
{"title":"Translational Neuropsychopharmacology for Major Depression: Targeting Neurotransmitter Systems","authors":"Hyewon Kim, Yong-Ku Kim, H. Jeon","doi":"10.1007/978-1-0716-2083-0_15","DOIUrl":"https://doi.org/10.1007/978-1-0716-2083-0_15","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51713148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2022-9_14
Eric Verschooten, P. Joris
{"title":"Measurement of Human Cochlear and Auditory Nerve Potentials","authors":"Eric Verschooten, P. Joris","doi":"10.1007/978-1-0716-2022-9_14","DOIUrl":"https://doi.org/10.1007/978-1-0716-2022-9_14","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51711293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2026-7_10
T. Tarpin, Victor Llobet, G. Dugué, Z. Piwkowska, A. P. Varani, A. Khilkevich, D. DiGregorio, D. Popa, C. Léna
{"title":"Multi-site Extracellular Electrode Neuronal in the Rodent Cerebellar and Nuclei","authors":"T. Tarpin, Victor Llobet, G. Dugué, Z. Piwkowska, A. P. Varani, A. Khilkevich, D. DiGregorio, D. Popa, C. Léna","doi":"10.1007/978-1-0716-2026-7_10","DOIUrl":"https://doi.org/10.1007/978-1-0716-2026-7_10","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51711717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2083-0_11
M. Tiger, J. Lundberg
{"title":"Molecular Imaging of Major Depressive Disorder with Positron Emission Tomography: Translational Implications for Neurobiology and Treatment","authors":"M. Tiger, J. Lundberg","doi":"10.1007/978-1-0716-2083-0_11","DOIUrl":"https://doi.org/10.1007/978-1-0716-2083-0_11","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51712994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2083-0_3
M. Amidfar, Yong-Ku Kim
{"title":"Neural Circuits Underlying the Pathophysiology of Major Depression","authors":"M. Amidfar, Yong-Ku Kim","doi":"10.1007/978-1-0716-2083-0_3","DOIUrl":"https://doi.org/10.1007/978-1-0716-2083-0_3","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51713508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2083-0_4
M. Bourin
{"title":"Translational Research Approach to Neurobiology and Treatment of Major Depression: From Animal Models to Clinical Treatment","authors":"M. Bourin","doi":"10.1007/978-1-0716-2083-0_4","DOIUrl":"https://doi.org/10.1007/978-1-0716-2083-0_4","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51713601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01DOI: 10.1007/978-1-0716-2083-0_9
M. Amidfar, Yong-Ku Kim
{"title":"The Effects of Antidepressants on Neurotransmission: Translational Insights from In Vivo Electrophysiological Studies","authors":"M. Amidfar, Yong-Ku Kim","doi":"10.1007/978-1-0716-2083-0_9","DOIUrl":"https://doi.org/10.1007/978-1-0716-2083-0_9","url":null,"abstract":"","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51714146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuromethodsPub Date : 2022-01-01Epub Date: 2022-05-27DOI: 10.1007/978-1-0716-2039-7_21
Ishmail Abdus-Saboor, Wenqin Luo
{"title":"Measuring Mouse Somatosensory Reflexive Behaviors with High-speed Videography, Statistical Modeling, and Machine Learning.","authors":"Ishmail Abdus-Saboor, Wenqin Luo","doi":"10.1007/978-1-0716-2039-7_21","DOIUrl":"10.1007/978-1-0716-2039-7_21","url":null,"abstract":"<p><p>Objectively measuring and interpreting an animal's sensory experience remains a challenging task. This is particularly true when using preclinical rodent models to study pain mechanisms and screen for potential new pain treatment reagents. How to determine their pain states in a precise and unbiased manner is a hurdle that the field will need to overcome. Here, we describe our efforts to measure mouse somatosensory reflexive behaviors with greatly improved precision by high-speed video imaging. We describe how coupling sub-second ethograms of reflexive behaviors with a statistical reduction method and supervised machine learning can be used to create a more objective quantitative mouse \"pain scale.\" Our goal is to provide the readers with a protocol of how to integrate some of the new tools described here with currently used mechanical somatosensory assays, while discussing the advantages and limitations of this new approach.</p>","PeriodicalId":74285,"journal":{"name":"Neuromethods","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249079/pdf/nihms-1702641.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}