American journal of cardiovascular disease最新文献

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Impact of risk factors on intervened and non-intervened coronary lesions. 风险因素对介入和非介入冠状动脉病变的影响。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/XTBG3549
Xincheng Sheng, Gan Yang, Qing Zhang, Yong Zhou, Jun Pu
{"title":"Impact of risk factors on intervened and non-intervened coronary lesions.","authors":"Xincheng Sheng, Gan Yang, Qing Zhang, Yong Zhou, Jun Pu","doi":"10.62347/XTBG3549","DOIUrl":"10.62347/XTBG3549","url":null,"abstract":"<p><strong>Introduction: </strong>In-stent restenosis (ISR) and aggravated non-intervened coronary lesions (ANL) are two pivotal aspects of disease progression in patients with coronary artery disease (CAD). Established risk factors for both include hyperlipidemia, hypertension, diabetes, chronic kidney disease, and smoking. However, there is limited research on the comparative risk factors for the progression of these two aspects of progression. The aim of this study was to analyze and compare the different impacts of identical risk factors on ISR and ANL.</p><p><strong>Methods: </strong>This study enrolled a total of 510 patients with multiple coronary artery lesions who underwent repeated coronary angiography (CAG). All patients had previously undergone percutaneous coronary intervention (PCI) and presented non-intervened coronary lesions in addition to the previously intervened vessels.</p><p><strong>Results: </strong>After data analysis, it was determined that HbA1c (OR 1.229, 95% CI 1.022-1.477, P=0.028) and UA (OR 1.003, 95% CI 1.000-1.005, P=0.024) were identified as independent risk factors for ISR. Furthermore, HbA1c (OR 1.215, 95% CI 1.010-1.460, P=0.039), Scr (OR 1.007, 95% CI 1.003-1.017, P=0.009), and ApoB (OR 1.017, 95% CI 1.006-1.029, P=0.004) were identified as independent risk factors for ANL. The distribution of multiple blood lipid levels differed between the ANL only group and the ISR only group. Non-HDL-C (2.17 mmol/L vs. 2.44 mmol/L, P=0.007) and ApoB (63.5 mg/dL vs. 71.0 mg/dL, P=0.011) exhibited significantly higher values in the ANL only group compared to the ISR only group.</p><p><strong>Conclusions: </strong>Blood glucose levels and chronic kidney disease were identified as independent risk factors for both ISR and ANL, while elevated lipid levels were only significantly associated with ANL. In patients with non-intervened coronary lesions following PCI, it is crucial to assess the concentration of non-HDL-C and ApoB as they serve as significant risk factors.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptomatic idiopathic pulmonary artery aneurysm: a case report and a mini-review of the literature. 症状性特发性肺动脉瘤:病例报告和文献综述。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/DBOS5122
Caitlin Merrin, Nyein Chan Swe, George Degheim
{"title":"Symptomatic idiopathic pulmonary artery aneurysm: a case report and a mini-review of the literature.","authors":"Caitlin Merrin, Nyein Chan Swe, George Degheim","doi":"10.62347/DBOS5122","DOIUrl":"10.62347/DBOS5122","url":null,"abstract":"<p><p>Pulmonary artery aneurysms (PAAs) are rare, more prevalent in younger population with equal sex incidence. Congenital, idiopathic, autoimmune, infectious, inflammatory, and malignant etiologies have been linked to PAAs. Commonly, patients with PAA are asymptomatic, even those with large PAAs. Presenting symptoms, if any, are non-specific. The management should target the underlying conditions and serial imaging follow-up. Signs and symptoms of disease progression should prompt a change in treatment strategy. Though there is no consensus, those who are symptomatic with a PAA diameter > 5 cm generally should undergo surgical repair. More recently, endovascular interventions are available for certain PAAs. We present a 78-year-old female who was referred to the cardiology clinic for cough and dyspnea. Using computed tomography (CTA) of the chest, she was diagnosed with aneurysm of the main pulmonary artery (PA), without involvement of distal pulmonary arteries or thoracic aorta. She underwent repair of the pulmonary artery using a 34-mm tubular graft with a complete resolution of her symptoms.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-world data on the effectiveness of TYRX and TauroPace for preventing CIED infections. 关于 TYRX 和 TauroPace 预防 CIED 感染有效性的真实世界数据。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/DSHG1684
Andrea Messori, Maria Rita Romeo, Melania Rivano, Sabrina Trippoli
{"title":"Real-world data on the effectiveness of TYRX and TauroPace for preventing CIED infections.","authors":"Andrea Messori, Maria Rita Romeo, Melania Rivano, Sabrina Trippoli","doi":"10.62347/DSHG1684","DOIUrl":"10.62347/DSHG1684","url":null,"abstract":"<p><strong>Background: </strong>The implantation of cardiac implantable electronic devices (CIEDs) carries a known risk of infection. Two devices (TYRX and TauroPace) have been proposed to reduce this risk.</p><p><strong>Methods: </strong>The aim of our study was to compare the effectiveness of TauroPace and TYRX. Real-world comparative studies were included. Data analysis was based on reconstruction of individual patient data from Kaplan-Meier curves using an artificial intelligence algorithm. The endpoint was CIED infection or systemic infection. Statistical tests included heterogeneity assessment, superiority testing, and non-inferiority testing. The primary outcome measure was the hazard ratio (HR) with confidence interval (CI).</p><p><strong>Results: </strong>Our literature search identified two real-world studies suitable for our analysis. Follow-up was 12 months for TauroPace (654 patients) and 60 months for TYRX (872 patients), with a total of 2,083 controls. There was no heterogeneity among controls. Compared to the pooled control group, patients treated with TYRX or TauroPace had fewer CIED infections (HR, 0.3892; 95% CI, 0.2042-0.7419; P=0.00414; HR, 0.3313; 95% CI, 0.1005-1.0925; P=0.06958, respectively). When testing for non-inferiority of TauroPace vs. TYRX, the comparison yielded a HR of 0.8494 (in favor of TYRX) with a 90% CI of 0.27-2.63; this CI of TauroPace did not meet the non-inferiority criterion set at HR>0.75 (i.e., relative difference ≤25%).</p><p><strong>Conclusions: </strong>Both treatments had some important drawbacks. Regarding TYRX, more selective use in higher-risk patients should be advocated to improve its cost-effectiveness, but robust evidence is still lacking. Regarding TauroPace, our analysis testing for a non-inferiority margin of ≤25% did not meet this demonstration.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the impact of metabolites function on heart failure and coronary heart disease: insights from a Mendelian randomization (MR) study. 探索代谢物功能对心力衰竭和冠心病的影响:孟德尔随机化(MR)研究的启示。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/OQXZ7740
Vicheth Virak, Pengkhun Nov, Deshu Chen, Xuwei Zhang, Junjie Guan, Dongdong Que, Jing Yan, Vanna Hen, Senglim Choeng, Chongbin Zhong, Pingzhen Yang
{"title":"Exploring the impact of metabolites function on heart failure and coronary heart disease: insights from a Mendelian randomization (MR) study.","authors":"Vicheth Virak, Pengkhun Nov, Deshu Chen, Xuwei Zhang, Junjie Guan, Dongdong Que, Jing Yan, Vanna Hen, Senglim Choeng, Chongbin Zhong, Pingzhen Yang","doi":"10.62347/OQXZ7740","DOIUrl":"10.62347/OQXZ7740","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF) and coronary heart disease (CHD) are major causes of morbidity and mortality worldwide. While traditional risk factors such as hypertension, diabetes, and smoking have been extensively studied, the role of metabolite functions in the development of these cardiovascular conditions has been less explored. This study employed a Mendelian randomization (MR) approach to investigate the impact of metabolite functions on HF and CHD.</p><p><strong>Methods: </strong>To assess the causal impacts of specific metabolite risk factors on HF and CHD, this study utilized genetic variants associated with these factors as instrumental variables. Comprehensive genetic and phenotypic data from diverse cohorts, including genome-wide association studies (GWAS) and cardiovascular disease registries, were incorporated into the research.</p><p><strong>Results: </strong>Our results encompass 61 metabolic cell phenotypes, with ten providing strong evidence of the influence of metabolite functions on the occurrence of HF and CHD. We found that elevated levels of erucate (22:1n9), lower levels of α-tocopherol, an imbalanced citrulline-to-ornithine ratio, elevated γ-glutamyl glycine levels, and elevated 7-methylguanine levels independently increased the risk of these cardiovascular conditions. These findings were consistent across different populations and robust to sensitivity analyses.</p><p><strong>Conclusion: </strong>This MR study provides valuable insights into the influence of metabolite functions on HF and CHD. However, further investigation is needed to fully understand the precise mechanisms by which these metabolite factors contribute to the onset of these conditions. Such research could pave the way for the development of targeted therapeutic strategies.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the effect of cancer medication in the development of Takotsubo cardiomyopathy. 研究癌症药物在塔克次博心肌病发病过程中的影响。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/STFL9135
On Chen, Azad Mojahedi
{"title":"Investigating the effect of cancer medication in the development of Takotsubo cardiomyopathy.","authors":"On Chen, Azad Mojahedi","doi":"10.62347/STFL9135","DOIUrl":"10.62347/STFL9135","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy (TCM) is a cardiac condition that is usually characterized by sudden heart failure (HF) or chest pain that resembles acute coronary syndrome (ACS). It is identified by severe systolic dysfunction of the left ventricle (LV) and can be caused by physical, medical, or emotional stress. The pathophysiological mechanisms leading to TCM have not yet been clearly determined. TCM is a complex condition to diagnose and may go undetected during cancer treatment due to the wide variety of cardiotoxic effects associated with antineoplastic therapies. Consequently, timely identification and effective treatment are critical to enhancing the prognosis. Nevertheless, TCM is a more prevalent condition in oncology than was previously believed; therefore, clinicians who treat cancer patients should consider it in their differential diagnosis. The purpose of this manuscript is to provide physicians with a summary of the available evidence regarding the ramifications of the association between TCM and cancer to aid in improving patient management.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A diagnostic prediction model for the early detection of heart failure following primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction. ST段抬高型心肌梗死患者经皮冠状动脉介入治疗后早期发现心力衰竭的诊断预测模型。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/SHPZ1673
Lingling Zhang, Zhican Liu, Yunlong Zhu, Jianping Zeng, Haobo Huang, Wenbin Yang, Ke Peng, Mingxin Wu
{"title":"A diagnostic prediction model for the early detection of heart failure following primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction.","authors":"Lingling Zhang, Zhican Liu, Yunlong Zhu, Jianping Zeng, Haobo Huang, Wenbin Yang, Ke Peng, Mingxin Wu","doi":"10.62347/SHPZ1673","DOIUrl":"10.62347/SHPZ1673","url":null,"abstract":"<p><strong>Background: </strong>In this study, we aimed to construct a robust diagnostic model that can predict the early onset of heart failure in patients with ST-elevation myocardial infarction (STEMI) following a primary percutaneous coronary intervention (PCI). This diagnostic model can facilitate the early stratification of high-risk patients, thereby optimizing therapeutic management.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 664 patients with STEMI who underwent their inaugural PCI. We performed logistic regression along with optimal subset regression and identified important risk factors associated with the early onset of heart failure during the time of admission. Based on these determinants, we constructed a predictive model and confirmed its diagnostic precision using a receiver operating characteristic (ROC) curve.</p><p><strong>Results: </strong>The logistic and optimal subset regression analyses revealed the following three salient risk factors crucial for the early onset of heart failure: the Killip classification, the presence of renal insufficiency, and increased troponin T levels. The constructed prognostic model exhibited excellent discriminative ability, which was indicated by an area under the curve value of 0.847. The model's 95% confidence interval following 200 Bootstrap iterations was found to be between 0.767 and 0.925. The Hosmer-Lemeshow test revealed a chi-square value of 3.553 and a <i>p</i>-value of 0.938. Notably, the calibration of the model remained stable even after 500 Bootstrap evaluations. Furthermore, decision curve analysis revealed a substantial net benefit of the model.</p><p><strong>Conclusion: </strong>We have successfully constructed a diagnostic prediction model to predict the incipient stages of heart failure in patients with STEMI following primary PCI. This diagnostic model can revolutionize patient care, allowing clinicians to quickly identify and create individualized interventions for patients at a higher risk.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A normal and particularly small (<35 mm) left atrial size measured during echocardiography suggests low likelihood of moderate or severe left ventricular systolic dysfunction. 超声心动图测量到的左心房大小正常且特别小(<35 毫米),表明中度或重度左心室收缩功能障碍的可能性较低。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-08-25 eCollection Date: 2024-01-01 DOI: 10.62347/YJTK3145
Mohammad Reza Movahed, Arman Soltani Moghadam
{"title":"A normal and particularly small (<35 mm) left atrial size measured during echocardiography suggests low likelihood of moderate or severe left ventricular systolic dysfunction.","authors":"Mohammad Reza Movahed, Arman Soltani Moghadam","doi":"10.62347/YJTK3145","DOIUrl":"10.62347/YJTK3145","url":null,"abstract":"<p><strong>Introduction: </strong>The left atrium (LA) size can change due to cardiac pathologies like heart failure and aging. While the link between LA enlargement and left ventricular (LV) dysfunction is acknowledged, this study aims to assess the negative predictive value of normal LA size concerning the severity of LV systolic function in a large cohort undergoing diagnostic echocardiography.</p><p><strong>Methods: </strong>This retrospective cohort study, conducted at the University of California, Irvine Medical Center from 1984 to 1998, aimed to elucidate the negative predictive value of normal LA size measured by M-mode and two-dimensional echocardiography in a large cohort undergoing diagnostic assessment.</p><p><strong>Results: </strong>In the analysis of 22,390 echocardiograms, 55.1% exhibited normal LA size (<40 mm), while 44.9% showed abnormal LA size (≥40 mm). Within the normal LA size group, only 2.4% demonstrated abnormal LV systolic function, with 1.1% mildly depressed, 0.7% moderately depressed, and 0.6% severely depressed LV function. The negative predictive value of normal LA size for abnormal LV systolic function was calculated at 97.5%, rising to 99.3% and 99.4% for moderate or severely decreased LV systolic function, respectively. In patients with small LA size (<35 mm), moderate to severely depressed LV systolic function was observed in only 0.8%, with severe LV systolic dysfunction in 0.3%, yielding an overall prevalence of 1.5% for all systolic dysfunction in the small LA size group.</p><p><strong>Conclusion: </strong>Our findings underscore the clinical significance of normal LA size as a reliable indicator of preserved LV function.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating antiarrhythmic drugs for managing infants with supraventricular tachycardia; a review. 评估用于治疗室上性心动过速婴儿的抗心律失常药物;综述。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-06-15 eCollection Date: 2024-01-01 DOI: 10.62347/ZTXC5809
Azad Mojahedi, Afsaneh Mirshekari
{"title":"Evaluating antiarrhythmic drugs for managing infants with supraventricular tachycardia; a review.","authors":"Azad Mojahedi, Afsaneh Mirshekari","doi":"10.62347/ZTXC5809","DOIUrl":"10.62347/ZTXC5809","url":null,"abstract":"<p><p>Supraventricular tachycardia (SVT) is the most prevalent arrhythmia observed in infants, impacting individuals with or without congenital cardiac dysfunction. Infantile-onset SVT typically manifests within the initial one to two months of life. A variety of anti-arrhythmic medications are employed to treat SVT in infants during their first year of life. Nevertheless, a consensus has yet to be reached on the most efficacious drug, and treatment approaches continue to vary considerably As SVT remains a frequent problem around the world, with different management approaches and no obvious optimal option, we conducted a systematic review of the new update of antiarrhythmic drugs for managing SVT in infants under one year old.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disparities by sex, race, and region in acute myocardial infarction-related outcomes during the early COVID-19 pandemic: the national inpatient sample analysis. 早期 COVID-19 大流行期间急性心肌梗死相关结果的性别、种族和地区差异:全国住院病人样本分析。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-06-15 eCollection Date: 2024-01-01 DOI: 10.62347/WKBJ1501
Harshith Thyagaturu, Amro Taha, Shafaqat Ali, Nicholas Roma, Sanchit Duhan, Neel Patel, Yasar Sattar, Karthik Gonuguntla, Harigopal Sandhyavenu, Irisha Badu, Erin D Michos, Sudarshan Balla
{"title":"Disparities by sex, race, and region in acute myocardial infarction-related outcomes during the early COVID-19 pandemic: the national inpatient sample analysis.","authors":"Harshith Thyagaturu, Amro Taha, Shafaqat Ali, Nicholas Roma, Sanchit Duhan, Neel Patel, Yasar Sattar, Karthik Gonuguntla, Harigopal Sandhyavenu, Irisha Badu, Erin D Michos, Sudarshan Balla","doi":"10.62347/WKBJ1501","DOIUrl":"10.62347/WKBJ1501","url":null,"abstract":"<p><strong>Background: </strong>Disparities in acute myocardial infarction (AMI)-related outcomes have been reported before the COVID-19 pandemic. We studied in-hospital outcomes of AMI across demographic groups in the United States during the early COVID-19 pandemic.</p><p><strong>Methods: </strong>The National Inpatient Sample (NIS) database was queried for 2020 to identify AMI-related hospitalizations based on appropriate ICD-10-CM codes categorized by sex, race, and hospital region categories. The primary outcome was in-hospital mortality in females, racial and ethnic minority groups, and Northeast hospital region compared with males, White patients, and Midwest hospital region, respectively. Multivariable regression analysis was used to calculate the adjusted odds ratio and mean difference.</p><p><strong>Results: </strong>A total of 820,893 AMI-related hospitalizations were identified during the study period. On adjusted analysis, during the early COVID-19 pandemic, females had lower odds of in-hospital mortality [aOR 0.89 (0.85-0.92); P < 0.01] and revascularization [aOR 0.68 (0.66-0.69); P < 0.01] than males. Racial and ethnic based analysis showed that Asian/Pacific Islander patients had higher odds of in-hospital mortality [aOR 1.13 (1.03-1.25); P < 0.01] than White patients. During the early COVID-19 pandemic, Northeast and Western region hospitals had higher odds of in-hospital mortality, lower odds of revascularization, longer length of stay, and higher total hospitalization costs than Midwest region hospitals.</p><p><strong>Conclusions: </strong>Our study disclosed disparities in AMI-related mortality and revascularization by sex, race and ethnic, and region during the early COVID-19 pandemic. Special attention should be given to at-risk populations. Whether these disparities continue in the post-vaccination era warrants further study.</p>","PeriodicalId":7427,"journal":{"name":"American journal of cardiovascular disease","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous coronary intervention involving coronary bifurcation is associated with higher mortality and complications. 涉及冠状动脉分叉的经皮冠状动脉介入治疗与较高的死亡率和并发症有关。
IF 1.3
American journal of cardiovascular disease Pub Date : 2024-06-15 eCollection Date: 2024-01-01 DOI: 10.62347/XDDB4510
Allistair Nathan, Mehrtash Hashemzadeh, Mohammad Reza Movahed
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