{"title":"[The microbiome and the first 1,000 days of life].","authors":"E Zaura","doi":"10.5177/ntvt.2025.03.24064","DOIUrl":"10.5177/ntvt.2025.03.24064","url":null,"abstract":"<p><p>A healthy human being lives in symbiosis with his microbes or microbiome. The first 1,000 days of life are crucial for developing a healthy and diverse microbiome. The development of a healthy microbiome begins as early as in the womb, where the training of the fetal immune cells begins. Next, the child s microbiome is influenced by the method of delivery during the birthing process. The largest and most important phase is the postnatal period. In this last phase, the child s environment, the behaviour and lifestyle of its caregivers, and the child itself are the main determinants of developing and maintaining a healthy microbiome.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 3","pages":"112-117"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A child s first 1,000 days: its relevance to the oral care practice].","authors":"T J Roseboom","doi":"10.5177/ntvt.2025.03.24122","DOIUrl":"10.5177/ntvt.2025.03.24122","url":null,"abstract":"<p><p>Every human life begins as a single, fertilized egg-cell. During the first 1,000 days of life, this cell develops into a 2-year-old toddler. More milestones are reached in this period of life than in any other. All organs are formed, the metabolism is set up, the microbiome is formed, the child learns to eat and drink, develops eating habits, food preferences, and learns to walk and talk. The environment in which these developments take place is crucial to health in later life. The established structures and systems will last for life and will thus have a life-long influence on the individual s general health. Due to the regular check-ups they carry out and their expertise in the field of preventive medicine, oral care providers can make an important contribution during this unique window of opportunity. This article summarizes why the first 1,000 days are important, and describes how oral care providers can contribute. Together with parents (to be) and children, they can build healthy habits, help prevent caries, obesity, diabetes, cardiovascular disease and other chronic disorders, and be part of building the health of present and future generations.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 3","pages":"118-123"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The first 1,000 days in molar-incisor hypomineralization and hypomineralized second primary molars].","authors":"M Elfrink","doi":"10.5177/ntvt.2025.03.24121","DOIUrl":"10.5177/ntvt.2025.03.24121","url":null,"abstract":"<p><p>In the first 1,000 days a large part of the enamel formation of the second primary molars, first permanent molars and permanent incisors takes place. If anything goes wrong during this period, this may have permanent implications for the enamel. If this occurs during the mineralization phase, it can be seen as hypomineralization of second primary molars (HSPM) and/or molar-incisor hypomineralization (MIH). The enamel of hypomineralized second primary molars and hypomineralized molar-incisors is less hard, less elastic and less beautiful. Due to a different composition of the enamel (more protein, fewer minerals) the attachment of restoration materials to hypomineralized enamel is more difficult. The aetiology of hypomineralized second primary molars and molar-incisor hypomineralization is multifactorial. Many potential aetiological factors have been investigated, but more insight still has to be gained into how different factors interact and what influence each factor has. Further longitudinal research into the possible aetiology of hypomineralized second primary molars and molar-incisor hypomineralization will be necessary to better understand how and why hypomineralization of the enamel occurs.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 3","pages":"124-129"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The first visit to the dental care practice].","authors":"C C Bonif Cio, D Hesse","doi":"10.5177/ntvt.2025.03.24129","DOIUrl":"10.5177/ntvt.2025.03.24129","url":null,"abstract":"<p><p>During a child s first 1,000 days, many important events take place, such as the eruption of its first tooth, taking its first bite, learning to brush its teeth and the first visits to a dental care practice. This article discusses the factors influencing a child s oral health during this crucial period. It offers oral care providers guidelines for young children s first visits. It is essential for oral care providers to be able to recognize disorders among this patient group and to treat these, when necessary. In addition, during a first visit, parents questions are answered and subjects like non-nutritive sucking, eating habits, oral hygiene and other risk factors for early childhood caries (ECC) are raised. By supporting the parents and making them aware of the importance of oral health from birth, oral care providers can play an essential role in establishing a solid foundation for a healthy future.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 3","pages":"130-136"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Breastfeeding and the development of caries in children].","authors":"L Kragt","doi":"10.5177/ntvt.2025.03.24119","DOIUrl":"10.5177/ntvt.2025.03.24119","url":null,"abstract":"<p><p>The correlation between breastfeeding and the development of caries in children remains unclear. Previous studies have found a correlation between prolonged breastfeeding and the risk of caries. However, the associations observed were primarily based on non-European populations, and important confounding factors, such as socio-economic position and diet, were not taken into account. The Generation R study re-examined the relationship between breastfeeding and oral health. The results of this Dutch cohort study confirmed the previously observed associations between prolonged breastfeeding and the increased risk of dental caries, even after adjustments had been made for indicators of socio-economic position, ethnic background and sugar intake. Future studies are encouraged to further explore possible explanations for the observed correlations. Healthcare professionals should be more aware of this and advise patients about the potential risk of prolonged breastfeeding on the development of caries by applying current recommendations regarding breastfeeding, oral hygiene and frequency of feeding.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 3","pages":"138-143"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A J M Ligtenberg, F J Bikker, M L Laine, M R J Faruque
{"title":"[A PhD Completed. Restoring saliva production and quality by means of olfactory stimulation and synthetic peptides].","authors":"A J M Ligtenberg, F J Bikker, M L Laine, M R J Faruque","doi":"10.5177/ntvt.2025.02.24091","DOIUrl":"10.5177/ntvt.2025.02.24091","url":null,"abstract":"<p><p>Saliva is essential for oral health. Factors such as medication, chemotherapy and radiotherapy, and systemic diseases can reduce saliva production, which can lead to chronic dry mouth. This study focused on restoring both the quantity and quality of saliva. In a clinical study, healthy participants were exposed to volatiles from mastic resin and ?-pinene, while those with chronic dry mouth were exposed only to mastic resin, significantly increasing saliva secretion in both groups. In patients with dry mouth, saliva quality increased after exposure to mastic resin volatiles as could be deduced from increased spinnbarkeit, pH, sodium and MUC5B concentrations. Additionally, synthetic peptides were developed to specifically bind MUC5B using the phage display technique. The presence of peptide MBP12 stabilized the spinnbarkeit of saliva in vitro. Experiments in epitope characterization revealed that MBP12 bound to the galactose residue of MUC5B. These findings suggest that olfactory stimuli of mastic resin and MUC5B-binding peptides are promising, non-invasive methods for treating chronic dry mouth.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 2","pages":"70-73"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Silent sinus syndrome, a rare outcome of an orbital floor fracture].","authors":"L Dubois, R Noorlag, R Schreurs","doi":"10.5177/ntvt.2025.02.24080","DOIUrl":"10.5177/ntvt.2025.02.24080","url":null,"abstract":"<p><p>A 28-year-old man was referred to an oral and maxillofacial surgeon, complaining of fatigue, a tugging sensation in his right eye and difficulty focusing. Closer investigation revealed a progressive shifting of the position of the right eyeball as a result of silent sinus syndrome, as a delayed consequence of an orbital floor fracture. Although clinical symptoms usually occur soon after an orbital fracture, there are dormant sequelae that only develop later, such as the silent sinus syndrome. Displacement of the orbital floor can cause the infundibulum of the maxillary sinus to the nose to become obstructed. This can create a vacuum in the maxillary sinus which pulls the walls inwards. Since the roof of the sinus is also the floor of the orbit, a slow yet progressive change in the position of the eyeball can occur. In addition to a traumatic cause (orbital floor fracture), chronic sinusitis, possibly of odontogenic origin, can also be the cause of silent sinus syndrome. Early referral to an oral and maxillofacial surgeon prevents worsening of this syndrome.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 2","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Important medical-dental interactions. Medication and older people with frailty in the oral healthcare practice].","authors":"A Visser, A Vissink, F Benmhammed, M Mulder","doi":"10.5177/ntvt.2025.02.24115","DOIUrl":"10.5177/ntvt.2025.02.24115","url":null,"abstract":"<p><p>With ageing, chances of illness and physical problems increase; these are often accompanied by the need to use medication. With today s ageing of the population, oral healthcare providers will see increasing numbers of older people with multimorbidity and polypharmacy (using 5 or more different medicines) in their practice. Due to likely complications and possible interactions as a result of oral healthcare interventions, knowledge about health issues and medication used is of great importance. This article aims to inform the reader about issues concerning the use of medication by older people with frailty in the oral healthcare practice. Medicines most often used by older people, problems encountered by oral healthcare providers when acquiring proper insight into the medical situation of an older person with frailty (not merely physical but cognitive and social, too) and medical-dental interactions of medication used by older people are discussed.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 2","pages":"78-88"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Oral features of and treatment options for patients with ectodermal dysplasia 2].","authors":"D Termeer, J H F Liebregts, Y T W van der Zander","doi":"10.5177/ntvt.2025.02.24089","DOIUrl":"10.5177/ntvt.2025.02.24089","url":null,"abstract":"<p><p>Ectodermal dysplasia can present in various ways. A reduced number of constructed teeth, deformed teeth and an underdeveloped alveolar process are common oral features in ectodermal dysplasia. Although the dental treatment goal is always to restore function, there is no standard treatment protocol for this condition. The dental treatment plan must be individually tailored based on the oral situation, (technical) possibilities, age and wishes of the patient. This requires a multidisciplinary approach among different healthcare providers: a maxillofacial prosthodontist, an oral and maxillofacial surgeon, implantologist, orthodontist, a dental technician, speech therapist, dietician and a psychologist. In this second part of this two-part article, 2 cases of ectodermal dysplasia are presented.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 2","pages":"54-61"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Fifty years of all-ceramic restorations in dentistry 1].","authors":"J M van der Zel","doi":"10.5177/ntvt.2025.02.24052","DOIUrl":"10.5177/ntvt.2025.02.24052","url":null,"abstract":"<p><p>An overview of all-ceramic dental restorations during the past 50 years poses a challenge. This is mainly due to the great variety of manufacturing processes, which were just as essential to the quality and functioning of the restorations as the composition of the different ceramics. Developments and innovations in the field of all-ceramic restorations have greatly contributed to much better biocompatibility and aesthetics. Without CAD/CAM software and (intraoral) scanners, developments from the first all-ceramic restorations with feldspar porcelain in 1973 to today's milled lithium silicate or zirconium dioxide restorations would not have been possible. In this first of a two-part article, developments up to the advent of zirconium dioxide are presented.</p>","PeriodicalId":74255,"journal":{"name":"Nederlands tijdschrift voor tandheelkunde","volume":"132 2","pages":"90-94"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}