Natural sciences (Weinheim, Germany)最新文献

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Diverse roles for axon guidance pathways in adult tissue architecture and function. 轴突引导通路在成人组织结构和功能中的不同作用。
Natural sciences (Weinheim, Germany) Pub Date : 2022-10-01 Epub Date: 2022-10-02 DOI: 10.1002/ntls.20220021
Kaitlin M Laws, Greg J Bashaw
{"title":"Diverse roles for axon guidance pathways in adult tissue architecture and function.","authors":"Kaitlin M Laws,&nbsp;Greg J Bashaw","doi":"10.1002/ntls.20220021","DOIUrl":"10.1002/ntls.20220021","url":null,"abstract":"<p><p>Classical axon guidance ligands and their neuronal receptors were first identified due to their fundamental roles in regulating connectivity in the developing nervous system. Since their initial discovery, it has become clear that these signaling molecules play important roles in the development of a broad array of tissue and organ systems across phylogeny. In addition to these diverse developmental roles, there is a growing appreciation that guidance signaling pathways have important functions in adult organisms, including the regulation of tissue integrity and homeostasis. These roles in adult organisms include both tissue-intrinsic activities of guidance molecules, as well as systemic effects on tissue maintenance and function mediated by the nervous and vascular systems. While many of these adult functions depend on mechanisms that mirror developmental activities, such as regulating adhesion and cell motility, there are also examples of adult roles that may reflect signaling activities that are distinct from known developmental mechanisms, including the contributions of guidance signaling pathways to lineage commitment in the intestinal epithelium and bone remodeling in vertebrates. In this review, we highlight studies of guidance receptors and their ligands in adult tissues outside of the nervous system, focusing on <i>in vivo</i> experimental contexts. Together, these studies lay the groundwork for future investigation into the conserved and tissue-specific mechanisms of guidance receptor signaling in adult tissues.</p>","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346896/pdf/nihms-1830702.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9821498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Scents from the past: Lineage history and terminal identity in the olfactory system. 来自过去的气味:嗅觉系统的血统历史和终端身份。
Natural sciences (Weinheim, Germany) Pub Date : 2022-10-01 DOI: 10.1002/ntls.20220037
Sriivatsan G Rajan, Ankur Saxena
{"title":"Scents from the past: Lineage history and terminal identity in the olfactory system.","authors":"Sriivatsan G Rajan,&nbsp;Ankur Saxena","doi":"10.1002/ntls.20220037","DOIUrl":"https://doi.org/10.1002/ntls.20220037","url":null,"abstract":"The development of the vertebrate nose depends upon the interaction and intermingling of multiple progenitor subtypes, giving rise to olfactory epithelia that detect sensory information and transmit it to the brain.1,2 The olfactory epithelium is a dense and complex structure that houses numerous specialized cell types, including olfactory sensory neurons (OSNs) and, additionally, is thought to be the origin of migratory gonadotropin-releasing hormone (GnRH) neurons.2–4","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10363087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Singlet‐exciton optics and phonon‐mediated dynamics in oligoacene semiconductor crystals 寡聚丙烯酸半导体晶体中的单线态激子光学和声子介导动力学
Natural sciences (Weinheim, Germany) Pub Date : 2022-09-12 DOI: 10.1002/ntls.20220040
J. Thompson, D. Muth, Sebastian Anhäuser, D. Bischof, M. Gerhard, G. Witte, E. Malic
{"title":"Singlet‐exciton optics and phonon‐mediated dynamics in oligoacene semiconductor crystals","authors":"J. Thompson, D. Muth, Sebastian Anhäuser, D. Bischof, M. Gerhard, G. Witte, E. Malic","doi":"10.1002/ntls.20220040","DOIUrl":"https://doi.org/10.1002/ntls.20220040","url":null,"abstract":"Organic semiconductor crystals stand out as an efficient, cheap and diverse platform for realising optoelectronic applications. The optical response of these crystals is governed by a rich tapestry of exciton physics. So far, little is known on the phonon-driven singlet exciton dynamics in this class of materials. In this joint theory-experiment work, we combine the fabrication of a high-quality oligoacene semiconductor crystal and characterization via photoluminescence measurements with a sophisticated approach to the microscopic modeling in these crystals. This allows us to investigate singlet exciton optics and dynamics. We predict phonon-bottleneck effects in pentacene crystals, where we find dark excitons acting as crucial phonon-mediated relaxation scattering channels. While the efficient singlet fission in pentacene crystals hampers the experimental observation of this bottleneck effect, we reveal both in theory and experiment a distinct polarisation- and temperature-dependence in absorption and photoluminescence spectra of tetracene crystals, including microscopic origin of exciton linewidths, the activation of the higher Davydov states at large temperatures, and polarisation-dependent quenching of specific exciton resonances. Our joint theory-experiment study represents a significant advance in microscopic understanding of singlet exciton optics and dynamics in oligoacene crystals.","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89850738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The impact of optical excitation on the binding in complexes of the cationic gold dimer: Au2+N2${rm{Au}_{2}^{+}} {rm{N}_{2}} $ and Au2+N2O${rm{Au}_{2}^{+}} {rm{N}_{2}{rm{O}}} $ 光激发对阳离子金二聚体配合物结合的影响:Au2+N2${rm{Au}_{2}}^{+}} {rm{N}_{2}}和Au2+N2O${rm{Au}_{2}}} {rm{O}}} $
Natural sciences (Weinheim, Germany) Pub Date : 2022-08-19 DOI: 10.1002/ntls.20220023
M. Förstel, Nima‐Noah Nahvi, Kai Pollow, T. Studemund, Alice E. Green, A. Fielicke, S. Mackenzie, O. Dopfer
{"title":"The impact of optical excitation on the binding in complexes of the cationic gold dimer: Au2+N2${rm{Au}_{2}^{+}} {rm{N}_{2}} $ and Au2+N2O${rm{Au}_{2}^{+}} {rm{N}_{2}{rm{O}}} $","authors":"M. Förstel, Nima‐Noah Nahvi, Kai Pollow, T. Studemund, Alice E. Green, A. Fielicke, S. Mackenzie, O. Dopfer","doi":"10.1002/ntls.20220023","DOIUrl":"https://doi.org/10.1002/ntls.20220023","url":null,"abstract":"","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75596075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Convolutional neural network prediction of molecular properties for aerosol chemistry and health effects 卷积神经网络预测气溶胶化学和健康影响的分子特性
Natural sciences (Weinheim, Germany) Pub Date : 2022-08-18 DOI: 10.1002/ntls.20220016
Matteo Krüger, Jake Wilson, M. Wietzoreck, B. A. Bandowe, G. Lammel, B. Schmidt, U. Pöschl, T. Berkemeier
{"title":"Convolutional neural network prediction of molecular properties for aerosol chemistry and health effects","authors":"Matteo Krüger, Jake Wilson, M. Wietzoreck, B. A. Bandowe, G. Lammel, B. Schmidt, U. Pöschl, T. Berkemeier","doi":"10.1002/ntls.20220016","DOIUrl":"https://doi.org/10.1002/ntls.20220016","url":null,"abstract":"","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86698787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
2D/0D hierarchical heterostructures prepared via facet‐selective epitaxial growth of triangular Rh nanoplates on 2H‐Pd nanoparticles 三角形Rh纳米片在2H - Pd纳米颗粒表面选择性外延生长制备2D/0D分层异质结构
Natural sciences (Weinheim, Germany) Pub Date : 2022-08-11 DOI: 10.1002/ntls.20220026
Xixi Wang, Yiyao Ge, Qinghua Zhang, Ting Lin, Bo Chen, Lujiang Li, Zhiqi Huang, Qinbai Yun, Xichen Zhou, Zhenyu Shi, Guanghua Liu, Jiawei Liu, G. Wang, Long Zheng, B. Huang, Lingwen Liao, Yao Yao, Liying Zhai, Shiyao Lu, Qinxin Luo, Yenying W. Chen, Lin Gu, Hua Zhang
{"title":"2D/0D hierarchical heterostructures prepared via facet‐selective epitaxial growth of triangular Rh nanoplates on 2H‐Pd nanoparticles","authors":"Xixi Wang, Yiyao Ge, Qinghua Zhang, Ting Lin, Bo Chen, Lujiang Li, Zhiqi Huang, Qinbai Yun, Xichen Zhou, Zhenyu Shi, Guanghua Liu, Jiawei Liu, G. Wang, Long Zheng, B. Huang, Lingwen Liao, Yao Yao, Liying Zhai, Shiyao Lu, Qinxin Luo, Yenying W. Chen, Lin Gu, Hua Zhang","doi":"10.1002/ntls.20220026","DOIUrl":"https://doi.org/10.1002/ntls.20220026","url":null,"abstract":"","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91354387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The road toward imaging a black hole: A personal perspective 黑洞成像之路:个人视角
Natural sciences (Weinheim, Germany) Pub Date : 2022-08-01 DOI: 10.1002/ntls.20220031
H. Falcke
{"title":"The road toward imaging a black hole: A personal perspective","authors":"H. Falcke","doi":"10.1002/ntls.20220031","DOIUrl":"https://doi.org/10.1002/ntls.20220031","url":null,"abstract":"The images of the supermassive black holes Sgr A* and M87* by the Event Horizon Telescope (EHT) collaboration mark a special milestone in the history of the subject. For the first time we are able to see the shadow of black holes, testing basic predictions of the theory of general relativity. We are also now learning more about the fundamental astrophysical processes close to the event horizon that help to shape entire galaxies and even parts of our cosmos. The ultimate result was only possible due to a large collaborative effort of scientists and institutions around the world. The road towards these images was the result of a long sociological and scientific process. It started with early pathfinder experiments and a few simple ideas that were remarkably successful in predicting the basic observational signatures to look for. This was based on the premise that black holes are inherently simple objects. Here I describe this journey and some lessons learned from a personal perspective.","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90428995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multimodal imaging reveals a small subpopulation of Deinococcus radiodurans exhibiting correlated low superoxide radical levels with extraordinary silver ion metabolism 多模态成像显示耐辐射球菌小亚群表现出与异常银离子代谢相关的低超氧自由基水平
Natural sciences (Weinheim, Germany) Pub Date : 2022-07-28 DOI: 10.1002/ntls.20210507
Wei Zhu, Xinyu He, Haoran Li, Bo Jiang, Ruochen Xie, Wei Wang
{"title":"Multimodal imaging reveals a small subpopulation of\u0000 Deinococcus radiodurans\u0000 exhibiting correlated low superoxide radical levels with extraordinary silver ion metabolism","authors":"Wei Zhu, Xinyu He, Haoran Li, Bo Jiang, Ruochen Xie, Wei Wang","doi":"10.1002/ntls.20210507","DOIUrl":"https://doi.org/10.1002/ntls.20210507","url":null,"abstract":"","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81364860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Restructuring and integrity of molecular catalysts in electrochemical CO 2 reduction 电化学还原co2分子催化剂的结构调整与完整性研究
Natural sciences (Weinheim, Germany) Pub Date : 2022-07-15 DOI: 10.1002/ntls.20210628
Conor L. Rooney, Yueshen Wu, David J. Gallagher, Hailiang Wang
{"title":"Restructuring and integrity of molecular catalysts in electrochemical CO\u0000 2\u0000 reduction","authors":"Conor L. Rooney, Yueshen Wu, David J. Gallagher, Hailiang Wang","doi":"10.1002/ntls.20210628","DOIUrl":"https://doi.org/10.1002/ntls.20210628","url":null,"abstract":"","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"142 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78638045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Topological monopole's gauge field‐induced anomalous Hall effect in artificial honeycomb lattice 人工蜂窝晶格中拓扑单极子规范场诱导的反常霍尔效应
Natural sciences (Weinheim, Germany) Pub Date : 2022-07-12 DOI: 10.1002/ntls.20210083
Jiasen Guo, V. Dugaev, A. Ernst, G. Yumnam, Pousali Ghosh, D. Singh
{"title":"Topological monopole's gauge field‐induced anomalous Hall effect in artificial honeycomb lattice","authors":"Jiasen Guo, V. Dugaev, A. Ernst, G. Yumnam, Pousali Ghosh, D. Singh","doi":"10.1002/ntls.20210083","DOIUrl":"https://doi.org/10.1002/ntls.20210083","url":null,"abstract":"Vortex magnetic structure in artificial honeycomb lattice provides a unique platform to explore emergent properties due to the additional Berry phase curvature imparted by chiral magnetization to circulating electrons via direct interaction. We argue that while the perpendicularly-aligned magnetic component leads to the quantized flux of monopole at the center of the Berry sphere, the in-plane vortex circulation of magnetization gives rise to unexpected non-trivial topological Berry phase due to the gauge field transformation. The unprecedented effect signifies the importance of vector potential in multiply-connected geometrical systems. Experimental confirmations to proposed hypotheses are obtained from Hall resistance measurements on permalloy honeycomb lattice. Investigation of the topological gauge transformation due to the in-plane chirality reveals anomalous quasi-oscillatory behavior in Hall resistance $R_{xy}$ as function of perpendicular field. The oscillatory nature of $R_{xy}$ is owed to the fluctuation in equilibrium current as a function of Fermi wave-vector $k_F$, envisaged under the proposed new formulation in this article. Our synergistic approach suggests that artificially tunable nanostructured material provides new vista to the exploration of topological phenomena of strong fundamental importance.","PeriodicalId":74244,"journal":{"name":"Natural sciences (Weinheim, Germany)","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80539682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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