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Molecular biology (Los Angeles, Calif.)最新文献

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Abnormal mTOR Signaling Pathway Activity in Autism Spectrum Disorders: Prospects of Mechanism-Based Therapy 自闭症谱系障碍mTOR信号通路活性异常：基于机制的治疗前景
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020206
E. Trifonova, A. Kotliarova, A. Kochetov
{"title":"Abnormal mTOR Signaling Pathway Activity in Autism Spectrum Disorders: Prospects of Mechanism-Based Therapy","authors":"E. Trifonova, A. Kotliarova, A. Kochetov","doi":"10.1134/S0026893323020206","DOIUrl":"https://doi.org/10.1134/S0026893323020206","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"235-244"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41864036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of the Poly(ADP-Ribose) Polymerase 1 Level on the Status of Base Excision Repair in Human Cells 聚ADP核糖聚合酶1水平对人细胞碱基切除修复状态的影响
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020097
E. Ilina, A. S. Kochetkova, E. Belousova, M. Kutuzov, O. Lavrik, S. Khodyreva
{"title":"Influence of the Poly(ADP-Ribose) Polymerase 1 Level on the Status of Base Excision Repair in Human Cells","authors":"E. Ilina, A. S. Kochetkova, E. Belousova, M. Kutuzov, O. Lavrik, S. Khodyreva","doi":"10.1134/S0026893323020097","DOIUrl":"https://doi.org/10.1134/S0026893323020097","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"272-283"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41853438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanisms of the Specificity of the CRISPR/Cas9 System in Genome Editing CRISPR/Cas9系统在基因组编辑中的特异性机制
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020139
L. Kulishova, I. Vokhtantsev, D. V. Kim, D. O. Zharkov
{"title":"Mechanisms of the Specificity of the CRISPR/Cas9 System in Genome Editing","authors":"L. Kulishova, I. Vokhtantsev, D. V. Kim, D. O. Zharkov","doi":"10.1134/S0026893323020139","DOIUrl":"https://doi.org/10.1134/S0026893323020139","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"258-271"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47391880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alterations in the Level of mRNA of TPH1, TPH2 Genes, Tryptophan Hydroxylase Activity and Serotonin Metabolism in Mouse Brain Five Days after Lipopolysaccharide Administration 脂多糖给药5天后小鼠脑内TPH1、TPH2基因mRNA水平、色氨酸羟化酶活性和血清素代谢的变化
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020188
D. V. Sherbakov, A. B. Arefieva, P. D. Komleva, A. E. Iz'urov, N. Khotskin, D. Bazovkina, A. V. Kulikov
{"title":"Alterations in the Level of mRNA of TPH1, TPH2 Genes, Tryptophan Hydroxylase Activity and Serotonin Metabolism in Mouse Brain Five Days after Lipopolysaccharide Administration","authors":"D. V. Sherbakov, A. B. Arefieva, P. D. Komleva, A. E. Iz'urov, N. Khotskin, D. Bazovkina, A. V. Kulikov","doi":"10.1134/S0026893323020188","DOIUrl":"https://doi.org/10.1134/S0026893323020188","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"284-290"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46502458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geometric Approach to Phylogeographic Analysis Molecular Genetic Sequences: Principal Components and Dendrograms 系统发育地理分析的几何方法分子遗传序列：主成分和树状图
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S002689332302005X
V. Efimov, K. V. Efimov, V. Kovaleva
{"title":"Geometric Approach to Phylogeographic Analysis Molecular Genetic Sequences: Principal Components and Dendrograms","authors":"V. Efimov, K. V. Efimov, V. Kovaleva","doi":"10.1134/S002689332302005X","DOIUrl":"https://doi.org/10.1134/S002689332302005X","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"176-181"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47769502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Affecting the Stability of the Trimer of 2'-Deoxyuridine 5'-Triphosphate Nucleotide Hydrolase from Escherichia coli 影响大肠杆菌2'-脱氧尿苷5'-三磷酸核苷酸水解酶三聚体稳定性的因素
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S002689332302022X
A. Yudkina, E. Kovalenko, A. Endutkin, E. P. Panferova, A. Kirilenko, A. Kokhanenko, D. O. Zharkov
{"title":"Factors Affecting the Stability of the Trimer of 2'-Deoxyuridine 5'-Triphosphate Nucleotide Hydrolase from Escherichia coli","authors":"A. Yudkina, E. Kovalenko, A. Endutkin, E. P. Panferova, A. Kirilenko, A. Kokhanenko, D. O. Zharkov","doi":"10.1134/S002689332302022X","DOIUrl":"https://doi.org/10.1134/S002689332302022X","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"312-319"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46557039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Genes Associated with Increased Stress Sensitivity in Hypertensive ISIAH Rats 高血压ISIAH大鼠应激敏感性增高相关基因
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020073
L. A. Fedoseeva, S. E. Smolenskaya, A. Markel, O. Redina
{"title":"Genes Associated with Increased Stress Sensitivity in Hypertensive ISIAH Rats","authors":"L. A. Fedoseeva, S. E. Smolenskaya, A. Markel, O. Redina","doi":"10.1134/S0026893323020073","DOIUrl":"https://doi.org/10.1134/S0026893323020073","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"346-355"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44745401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo Usnic酸衍生酪氨酸- dna磷酸二酯酶1抑制剂单独或联合奥拉帕尼治疗体内移植肿瘤的效果
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020127
T. E. Kornienko, A. Zakharenko, E. Ilina, A. Chepanova, O. Zakharova, N. Dyrkheeva, N. Popova, V. Nikolin, A. Filimonov, O. Luzina, N. Salakhutdinov, O. Lavrik
{"title":"Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo","authors":"T. E. Kornienko, A. Zakharenko, E. Ilina, A. Chepanova, O. Zakharova, N. Dyrkheeva, N. Popova, V. Nikolin, A. Filimonov, O. Luzina, N. Salakhutdinov, O. Lavrik","doi":"10.1134/S0026893323020127","DOIUrl":"https://doi.org/10.1134/S0026893323020127","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"214-224"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48052397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Zwitter-Ionic Oligonucleotides: Preparation and Complementary Binding 新型两性离子寡核苷酸的制备及其互补结合
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-04-01 DOI: 10.1134/S0026893323020164
D. E. Patrushev, E. A. Burakova, S. N. Bizyaev, A. Fokina, D. Stetsenko
{"title":"New Zwitter-Ionic Oligonucleotides: Preparation and Complementary Binding","authors":"D. E. Patrushev, E. A. Burakova, S. N. Bizyaev, A. Fokina, D. Stetsenko","doi":"10.1134/S0026893323020164","DOIUrl":"https://doi.org/10.1134/S0026893323020164","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"15 1","pages":"320-328"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64064617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EBF1 Promotes the Sensitivity of Cervical Cancer Cells to Cisplatin via Activating FBN1 Transcription EBF1通过激活FBN1转录促进宫颈癌细胞对顺铂的敏感性
Molecular biology (Los Angeles, Calif.) Pub Date : 2023-03-03 DOI: 10.1134/S0026893323030093
N. Shen, J. H. Lin, P. Liu
{"title":"EBF1 Promotes the Sensitivity of Cervical Cancer Cells to Cisplatin via Activating FBN1 Transcription","authors":"N. Shen, J. H. Lin, P. Liu","doi":"10.1134/S0026893323030093","DOIUrl":"https://doi.org/10.1134/S0026893323030093","url":null,"abstract":"","PeriodicalId":74216,"journal":{"name":"Molecular biology (Los Angeles, Calif.)","volume":"57 1","pages":"491 - 501"},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42645416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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