American Journal of Kidney Diseases最新文献

{"title":"Variability in Estimated GFR: When the Signal Is the Noise","authors":"Ann M. O’Hare , Ziyad Al-Aly","doi":"10.1053/j.ajkd.2025.03.014","DOIUrl":"10.1053/j.ajkd.2025.03.014","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 6","pages":"Pages 676-678"},"PeriodicalIF":9.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Topiramate and Zonisamide Cause Kidney Stones?","authors":"Harshil A. Fichadiya , John C. Lieske","doi":"10.1053/j.ajkd.2025.04.001","DOIUrl":"10.1053/j.ajkd.2025.04.001","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 6","pages":"Pages 674-675"},"PeriodicalIF":9.4,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Income Dynamics and Risk of End-Stage Kidney Disease in Type 2 Diabetes: A South Korean Population-Based Cohort Study.","authors":"Min Woo Kang,Jae-Ik Oh,Jinsun Lee,Minsang Kim,Jung Hun Koh,Jeong Min Cho,Seong Geun Kim,Semin Cho,Soojin Lee,Yaerim Kim,Dong Ki Kim,Kyungdo Han,Sehoon Park","doi":"10.1053/j.ajkd.2025.02.609","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.02.609","url":null,"abstract":"RATIONALE & OBJECTIVEThe prevalence of end-stage kidney disease (ESKD) continues to rise, with socioeconomic status (SES), particularly income, having associations with ESKD risk among individuals with type 2 diabetes (T2D). This study examined the longitudinal association of income changes with ESKD risk among non-elderly adults with T2D in South Korea.STUDY DESIGNPopulation-based retrospective cohort study.SETTING & PARTICIPANTS1,481,371 adults aged 30 to 64 years with T2D represented in the South Korean National Health Insurance Service (NHIS) database in 2015 and 2016, followed to 2020.EXPOSURESustained income levels, income variability, and income changes over five years prior to entry into the study cohort.OUTCOMESPrimary outcome was progression to ESKD, defined as initiation of dialysis or kidney transplantation.ANALYTICAL APPROACHCox proportional hazards models were used to assess the risk of ESKD, adjusting for demographic, behavioral, and clinical variables.RESULTSCompared with those who never reached the lowest income quartile, individuals who spent any time (1-5 years) in the lowest quartile had a higher risk of ESKD (P for trend < 0.001). Conversely, spending 2-5 years in the highest quartile was significantly associated with a lower ESKD risk (P for trend < 0.001), whereas spending only 1 year in the highest quartile was not associated with ESKD risk. Income that dropped from a higher quartile to the lowest quartile was associated with higher risk, and even those moving from the lowest to the highest quartile had a higher ESKD risk than those who remained consistently in the highest quartile. Individuals with the highest income variability exhibited an increased risk of ESKD (hazard ratio 1.14, 95% confidence interval 1.01-1.29, P for trend = 0.02).LIMITATIONSResidual confounding, lack of data on medication adherence, and missing laboratory results.CONCLUSIONSDynamic changes in income were associated with ESKD risk among adults with T2D, findings that may inform healthcare policies that address the economic factors potentially contributing to kidney disease progression in South Korean adults with diabetes.","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"29 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Change in Small Solute Clearance Measurement in Patients Receiving Peritoneal Dialysis.","authors":"Jack Kit-Chung Ng,Winston Wing-Shing Fung,Gordon Chun-Kau Chan,Phyllis Mei-Shan Cheng,Wing-Fai Pang,Kai-Ming Chow,Cheuk-Chun Szeto","doi":"10.1053/j.ajkd.2025.02.608","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.02.608","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"17 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Multifocal Leukoencephalopathy in Kidney Transplant Recipients: A Retrospective Multicenter Nationwide Case Series.","authors":"Adélaïde Sanson,Yannis Lombardi,Rebecca Sberro-Soussan,François Provôt,Léonard Golbin,Samir Boudjeltia,Romain Pszczolinski,Christophe Masset,Anne-Sophie Vasseur,Jean-François Augusto,Hannah Kaminski,Eric Daugas,Sophie Caillard,Jean-Michel Rebibou,Valérie Moal,Moglie Le Quintrec,Renaud Snanoudj,Marie Matignon,Giovanna Melica,Julien Zuber,Laurent Mesnard,Nacera Ouali,Yosu Luque,Camille Petit-Hoang,Arnaud Del Bello,Nassim Kamar,Hélène François","doi":"10.1053/j.ajkd.2025.02.606","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.02.606","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"258 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LB-02 Re-Defining Carboplatin Dosage Using EGFR-Creatinine-Cystatin C Compared to Cockcroft Gault and Impact on Platinum-Associated Adverse Events","authors":"","doi":"10.1053/j.ajkd.2025.03.006","DOIUrl":"10.1053/j.ajkd.2025.03.006","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 5","pages":"Page 668"},"PeriodicalIF":9.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LB-07 Patients (PTS) in Duplex Achieved Partial or Complete Remission of Proteinuria Earlier and more Often with Sparsentan (SPAR) vs Irbesartan (IRB): Implications for Slowing Progression to Kidney Failure (KF) in Focal Segmental Glomerulosclerosis (FSGS)","authors":"","doi":"10.1053/j.ajkd.2025.03.011","DOIUrl":"10.1053/j.ajkd.2025.03.011","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 5","pages":"Page 670"},"PeriodicalIF":9.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malpighi's Forgotten Drawings of Renal Glomeruli.","authors":"Roberto F Nicosia,Paolo Cassoli","doi":"10.1053/j.ajkd.2025.01.026","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.01.026","url":null,"abstract":"Marcello Malpighi (1628-1694) is universally recognized for his pioneering work in microscopic anatomy. His groundbreaking studies of human, animal, and plant anatomy laid the foundation for modern histology, embryology, comparative anatomy, entomology, botany, and biology. Among his many contributions is the discovery of renal glomeruli, which he described as minimae glandulae (very small glands), attributing to them the production of urine. His treatise De renibus contained a detailed description of glomeruli but no images. A drawing of glomeruli by Malpighi appeared many years later on an illustrated manuscript sheet containing a plate with different types of glands, including the kidney's minimae glandulae. While examining Malpighi's handwritten scientific diary, kept at the Biblioteca Universitaria di Bologna, we found unpublished drawings of his kidney observations, including one that may represent his earliest extant depiction of glomeruli. This paper reviews Malpighi's groundbreaking discovery of glomeruli, focusing on his kidney drawings and their historical significance.","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"17 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LB-04 Association Between Baseline Serum Creatinine/Cystatin C (SCR/CYS) Ratio and Adverse Events in Patients Receiving Cisplatin or Carboplatin: A Prospective Cohort Study","authors":"","doi":"10.1053/j.ajkd.2025.03.008","DOIUrl":"10.1053/j.ajkd.2025.03.008","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 5","pages":"Page 669"},"PeriodicalIF":9.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Kidney Dysfunction With Weight Loss: A Quiz","authors":"Niveditha Girimaji,&nbsp;Emmanuel A. Adomako,&nbsp;Kerri McGreal,&nbsp;Duncan B. Johnstone","doi":"10.1053/j.ajkd.2024.10.011","DOIUrl":"10.1053/j.ajkd.2024.10.011","url":null,"abstract":"","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 5","pages":"Pages A14-A16"},"PeriodicalIF":9.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}