American Journal of Kidney Diseases最新文献_第3页

Peritoneal Dialysis in the United States: Growing Pains or Making Gains? 腹膜透析在美国：成长的烦恼还是收获？

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-09-02 DOI: 10.1053/j.ajkd.2025.08.002

Lawrence B. Slapcoff , Jeffrey Perl

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Operationalizing Environmental Sustainability in Kidney Care at System and Provider Levels: Knowledge Is the First Step 在系统和提供者层面实施肾脏护理的环境可持续性：知识是第一步。

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-09-02 DOI: 10.1053/j.ajkd.2025.08.001

Isabelle Ethier , Caroline Stigant

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From What to Why: Mechanistic Understandings Behind Sex Differences in Peritoneal Dialysis Discontinuation 从什么到为什么：腹膜透析中止的性别差异背后的机制理解。

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-09-01 DOI: 10.1053/j.ajkd.2025.08.003

Sandipan Shringi, Edward Medeiros, Ankur D. Shah

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Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2025 常染色体显性多囊肾病：核心课程2025

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-22 DOI: 10.1053/j.ajkd.2025.05.010

Craig E. Gordon , Pranav S. Garimella , Ronald D. Perrone , Dana C. Miskulin

{"title":"Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2025","authors":"Craig E. Gordon , Pranav S. Garimella , Ronald D. Perrone , Dana C. Miskulin","doi":"10.1053/j.ajkd.2025.05.010","DOIUrl":"10.1053/j.ajkd.2025.05.010","url":null,"abstract":"<div><div>Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of kidney failure. Scientific advances have improved the approach to diagnosis, prognosis, and management of renal and extrarenal manifestations. The combination of total kidney volume, kidney function, and the genetic mutation (if known), predicts risk for progression to kidney failure, thereby identifying patients in whom disease modifying therapy is recommended. Currently there is one therapy approved by the US Food and Drug Administration (FDA) for slowing ADPKD progression, the V2 receptor antagonist, tolvaptan. Other therapies are under active investigation for ADPKD. This Core Curriculum discusses diagnosis and management of the renal and extrarenal manifestations seen in ADPKD including acute and chronic pain and cyst infection and polycystic liver disease and intracranial aneurysm. Management of hypertension and women’s health and pregnancy management in ADPKD are covered. This review was aligned with the findings of the recently published Kidney Disease Improving Global Outcomes (KDIGO) clinical practice guideline for the Evaluation, Management, and Treatment of ADPKD.</div></div>","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"86 4","pages":"Pages 525-542"},"PeriodicalIF":8.2,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Transition of Care of Kidney Recipients from Transplant Centers to Referring Nephrologists: Report from the American Society of Transplantation Controversies Conference 肾受者的护理从移植中心转移到转诊肾科医生：来自美国移植争议会议的报告

IF 13.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-20 DOI: 10.1053/j.ajkd.2025.06.016

Prince Mohan Anand MD, Neeraj Singh MD, Gaurav Gupta MD, Mona Doshi MD, Bekir Tanriover MD, Deborah Adey MD, Krista L. Lentine MD PhD, Silke Niederhaus MD, Ronald F. Parsons MD, Alexander Wiseman MD, Matthew Cooper MD, Gary Singer MD, Darshana Dadhania MD, Roy D. Bloom MD

{"title":"Transition of Care of Kidney Recipients from Transplant Centers to Referring Nephrologists: Report from the American Society of Transplantation Controversies Conference","authors":"Prince Mohan Anand MD, Neeraj Singh MD, Gaurav Gupta MD, Mona Doshi MD, Bekir Tanriover MD, Deborah Adey MD, Krista L. Lentine MD PhD, Silke Niederhaus MD, Ronald F. Parsons MD, Alexander Wiseman MD, Matthew Cooper MD, Gary Singer MD, Darshana Dadhania MD, Roy D. Bloom MD","doi":"10.1053/j.ajkd.2025.06.016","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.06.016","url":null,"abstract":"The expanding number of surviving kidney transplant patients, driven in part by federal initiatives to increase transplant access for patients with advanced CKD, has strained the capacity of the existing transplant nephrology workforce to manage longer-term post-transplant recipients. As patients are living longer with working allografts, the need for effective long-term management has become very important. This can only be achieved by closer collaboration between transplant centers and referring nephrologists. There is, therefore, a great need for closer involvement of referring nephrologists in providing care for this medically complex patient population, necessitating ongoing bidirectional communication with transplant centers. The American Society of Transplantation Kidney Pancreas Community of Practice organized a Controversies Conference in October 2022 to identify major challenges and propose guidance for collaborative, safe and standardized care transition and longitudinal management of this population. This article summarizes the key themes, strategies, and recommendations that emerged from the conference, offering a roadmap for enhancing collaborative care models and supporting a sustainable system to manage the evolving needs of this medically complex patient population.","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"50 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum regarding “Continuous Kidney Replacement Therapies: Core Curriculum 2025” (Am J Kidney Dis. 2025;85(6):767-786) 关于“持续肾脏替代疗法：核心课程2025”的勘误（Am J Kidney Dis. 2025;85(6):767-786）

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-20 DOI: 10.1053/j.ajkd.2025.06.004

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A Patient With HIV and Nephrotic Range Proteinuria: A Quiz 1例HIV合并肾病性蛋白尿患者的测试

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-20 DOI: 10.1053/j.ajkd.2025.05.006

Ali Shah , Meghan Gwinn , Sayna Norouzi , Zainab Obaidi

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Missed Opportunities: Rethinking Primary Care Engagement in Dialysis-Dependent Populations 错失的机会：重新思考透析依赖人群的初级保健参与。

IF 8.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-19 DOI: 10.1053/j.ajkd.2025.07.001

Brittany N. Watson, Clarissa J. Diamantidis

引用次数: 0

Autosomal Dominant Tubulointerstitial Kidney Disease: A Review 常染色体显性小管间质肾病：综述

IF 13.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-18 DOI: 10.1053/j.ajkd.2025.05.015

Anthony J. Bleyer MD MS, Kendrah O. Kidd PhD, Martina Živná PhD, Stanislav Kmoch PhD

{"title":"Autosomal Dominant Tubulointerstitial Kidney Disease: A Review","authors":"Anthony J. Bleyer MD MS, Kendrah O. Kidd PhD, Martina Živná PhD, Stanislav Kmoch PhD","doi":"10.1053/j.ajkd.2025.05.015","DOIUrl":"https://doi.org/10.1053/j.ajkd.2025.05.015","url":null,"abstract":"Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an increasingly recognized rare condition with three primary characteristics: autosomal dominant inheritance, bland urinary sediment (absence of hematuria and proteinuria) and chronic kidney disease (CKD) leading to kidney failure (need for renal replacement therapy or kidney transplantation) between 20 and 80 years of age, with a mean age of kidney failure of approximately 45 years. Pathogenic variants in <ce:italic>UMOD</ce:italic>, <ce:italic>MUC1</ce:italic>, <ce:italic>REN</ce:italic>, and <ce:italic>APOA4</ce:italic> have been identified as causative in ADTKD families. Prior to 2000, ADTKD was only diagnosed clinically, and described in less than 50 families. However, with the advent of genetic testing and a better understanding of this condition, ADTKD is being increasingly recognized and is the third most common monogenic cause of kidney failure. The purpose of this review is to provide an understanding of the clinical characteristics of ADTKD, its subtypes and a practical approach to diagnosis and management for clinical nephrologists.","PeriodicalId":7419,"journal":{"name":"American Journal of Kidney Diseases","volume":"85 2 1","pages":""},"PeriodicalIF":13.2,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Metabolic Bariatric Surgery in Kidney Transplant Candidates 肾移植候选人的代谢减肥手术

IF 13.2 1区医学

American Journal of Kidney Diseases Pub Date : 2025-08-18 DOI: 10.1053/j.ajkd.2025.06.015

Aleksandra Kukla MD, Ricardo V. Cohen MD, Allon N. Friedman MD

引用次数: 0