Advances in wound care最新文献

{"title":"Prophylactic Negative Pressure Wound Therapy in Reducing Surgical Site Infections in Closed Abdominal Incision: A Randomized Controlled Trial.","authors":"Maharjan Manik, Amaranathan Anandhi, Sathasivam Sureshkumar, Andi Rajendharan Keerthi, Mahalingam Sudharshan, Vikram Kate","doi":"10.1089/wound.2023.0052","DOIUrl":"10.1089/wound.2023.0052","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to evaluate the efficacy of prophylactic negative pressure wound therapy (PNPWT) in reducing the incidence of surgical site infection (SSI) and other wound complications in closed abdominal incisions. <b>Approach:</b> This was a prospective, single-center, open-label parallel arm superiority randomized controlled trial conducted over 2 years. Participants were randomly assigned to PNPWT and standard surgical dressing (SSD) group. The occurrence of postoperative SSI within 30 days, other wound-related complications, length of hospital (LOH) stay, and readmission within 1 month among both the study group were studied. <b>Results:</b> A total of 140 participants were included, with 70 each randomized to the PNPWT and SSD groups. In this study, 28.5% and 5.8% developed SSI in the SSD and PNPWT groups, respectively (relative risk = 0.26; 95% confidence interval = 0.08-0.80; <i>p</i> = 0.001). Similarly, the incidence of seroma (7.2% vs. 18.5%, <i>p</i> = 0.016), wound dehiscence (0% vs. 4.2%, <i>p</i> = 0.244), superficial and deep SSI (5.7% vs. 24.3%, <i>p</i> = 0.001) and (0% vs. 4.2%, <i>p</i> = 0.244), and LOH stay (days) (9 vs. 10.5, <i>p</i> = 0.07) were less in PNPWT compared to SSD group. <b>Innovation:</b> Despite the advances in surgical care, SSI rates continue to be high. The present findings might facilitate the use of PNPWT as a novel preventive strategy to reduce SSI in closed abdominal incision. <b>Conclusion:</b> The PNPWT in closed incisions following elective laparotomy can reduce the incidence of SSI when compared to SSD. The use of PNPWT was associated with a lower incidence of superficial SSI and seroma but without significant reduction in hospital stay. <b>Clinical Trial Registry India:</b> CTRI/2020/11/028795.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"123-130"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrolyzed Collagen Powder Dressing Improves Wound Inflammation, Perfusion, and Breaking Strength of Repaired Tissue.","authors":"Manishekhar Kumar, Pradipta Banerjee, Amitava Das, Kanhaiya Singh, Tanner Guith, Sedat Kacar, Karthik Gourishetti, Chandan K Sen, Sashwati Roy, Savita Khanna","doi":"10.1089/wound.2023.0065","DOIUrl":"10.1089/wound.2023.0065","url":null,"abstract":"<p><p><b>Objective:</b> Hydrolyzed collagen-based matrices are widely used as wound care dressings. Information on the mechanism of action of such dressings is scanty. The objective of this study was to test the effect of a specific hydrolyzed collagen powder (HCP), which is extensively used for wound care management in the United States. <b>Approach:</b> The effects of HCP on resolution of wound inflammation, perfusion, closure, and breaking strength of the repaired skin were studied in an experimental murine model. <b>Results:</b> In early (day 7) inflammatory phase of wound macrophages, HCP treatment boosted phagocytosis and efferocytosis of wound-site macrophages. In these cells, inducible reactive oxygen species were also higher on day (d) 7. HCP treatment potentiated the expression of anti-inflammatory interleukin (IL)-10 cytokine and proangiogenic vascular endothelial growth factor (VEGF) production. Excisional wounds dressed with HCP showed complete closure on day 21, while the control wounds remained open. HCP treatment also demonstrated improved quality of wound healing as marked by the improved breaking strength of the closed wound tissue/repaired skin. <b>Innovation:</b> These data represent first evidence on the mechanism of action of clinically used HCP. <b>Conclusion:</b> HCP dressing favorably influenced both wound inflammation and vascularization. Improved breaking strength of HCP-treated repaired skin lays the rationale for future studies testing the hypothesis that HCP-treated closed wounds would show fewer recurrences.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"70-82"},"PeriodicalIF":5.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10218032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review of Fish-Based Biomaterial on Wound Healing and Anti-Inflammatory Processes.","authors":"M Gomathy, A John Paul, V Krishnakumar","doi":"10.1089/wound.2022.0142","DOIUrl":"10.1089/wound.2022.0142","url":null,"abstract":"<p><p><b>Objective:</b> To conduct a systematic literature review to study the effects of fish-based biomaterials on wound healing in both <i>in vivo</i> and <i>in vitro</i> animal models. <b>Approach:</b> This review covers the study reported in different articles between 2016 and August 2022 concentrating mainly on the cytotoxicity evaluation of different fish-based biomaterials on inflammation, reepithelialization and wound healing. <b>Significance:</b> This review shows considerable amount of research work carried out with fish-based biomaterials and collagen for treating burn wounds. Surprisingly there are only a few commercial products developed so far in this particular regard for surgical purpose and therefore, there is a way out and need for developing medical support product from fish-based biomaterials to treat and cure wounds. <b>Recent Advances:</b> Three-dimensional skin bioprinting technique is a large-scale solution for severe burn wounds that requires collagen as a raw material for printing, wherein fish collagen can be used in place of bovine and porcine, as it is biocompatible, promotes cell proliferation, adhesion, and migration, and degrades enzymatically. In the recent times, there are a few fish-based surgical products that have been formulated by Kerecis in United States. <b>Critical Issues:</b> The different fish-based biomaterial products are all mere supplements taken in orally as food or supplements till date and there is no proper proven medications that has been formulated so far in the field of wound healing and inflammation based on fish biomaterials except the surgical products that can be finger counted. <b>Future Directions:</b> Fish-based biomaterials are known for the medicinal properties that are used throughout the world and further investigations should be carried out to understand the actual physiochemical properties of its derivatives for the discovery of novel products and drugs.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"83-96"},"PeriodicalIF":4.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10073256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting Anaerobic Respiration in <i>Pseudomonas aeruginosa</i> with Chlorate Improves Healing of Chronic Wounds.","authors":"Jane H Kim, Melanie Spero, Elyson Gavin Lebig, Zachery R Lonergan, Inês B Trindade, Dianne K Newman, Manuela Martins-Green","doi":"10.1089/wound.2023.0036","DOIUrl":"10.1089/wound.2023.0036","url":null,"abstract":"<p><p><b>Objective:</b> <i>Pseudomonas aeruginosa</i> is an opportunistic pathogen that can establish chronic infections and form biofilm in wounds. Because the wound environment is largely devoid of oxygen, <i>P. aeruginosa</i> may rely on anaerobic metabolism, such as nitrate respiration, to survive in wounds. While nitrate reductase (Nar) typically reduces nitrate to nitrite, it can also reduce chlorate to chlorite, which is a toxic oxidizing agent. Therefore, chlorate can act as a prodrug to specifically eradicate hypoxic/anoxic, nitrate-respiring <i>P. aeruginosa</i> populations, which are often tolerant to conventional antibiotic treatments. <b>Approach:</b> Using a diabetic mouse model for chronic wounds, we tested the role that anaerobic nitrate respiration plays in supporting chronic <i>P. aeruginosa</i> infections. <b>Results:</b> <i>P. aeruginosa</i> forms biofilm deep within the wound where the environment is anoxic. Daily treatment of <i>P. aeruginosa</i>-infected wounds with chlorate supported wound healing. Chlorate treatment was as effective as a treatment with ciprofloxacin (a conventional antibiotic that targets both oxic and hypoxic/anoxic <i>P. aeruginosa</i> populations). Chlorate-treated wounds showed markers of good-quality wound healing, including well-formed granulation tissue, reepithelialization and microvessel development. Loss- and gain-of-function experiments showed that <i>P. aeruginosa</i> requires nitrate respiration to establish a chronic wound infection and form biofilms. <b>Innovation:</b> We show that the small molecule chlorate, kills the opportunistic pathogen, <i>P. aeruginosa</i>, by targeting a form of anaerobic metabolism called nitrate respiration. <b>Conclusion:</b> Chlorate holds promise as a treatment to combat diverse bacterial infections where oxygen is limiting and/or where pathogens grow as biofilms because many other pathogens possess Nar and survive using anaerobic metabolism.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"53-69"},"PeriodicalIF":4.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Biomaterials and Topical Medications for Treating Diabetic Foot Ulcers: A Systematic Review and Network Meta-Analysis.","authors":"Angela Chien-Yu Chen, Yi Lu, Chi-Ying Hsieh, Yo-Shen Chen, Ke-Chung Chang, Dun-Hao Chang","doi":"10.1089/wound.2023.0024","DOIUrl":"10.1089/wound.2023.0024","url":null,"abstract":"<p><p><b>Significance:</b> With the increasing diabetic population worldwide, diabetic foot ulcers (DFUs) are a significant concern. This study aimed to compare the efficacy of skin substitutes, biomaterials, and topical agents with standard care. <b>Recent Advances:</b> A meta-analysis was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, EMBASE, and Web of Science were searched using the following keywords: diabetes mellitus AND skin graft OR tissue replacement OR dressing OR drug. Two independent reviewers performed data collection and quality assessment of the eligible studies. The primary outcome was the 12- to 16-week healing rates and the secondary outcome was recurrence rates. <b>Critical Issues:</b> Thirty-eight randomized controlled trials, including 3,862 patients, were analyzed. The studies exhibited low heterogeneity (τ² = 0.10) without significant asymmetry (Egger's test, <i>p</i> = 0.8852). After pooling direct and indirect estimates, placenta-based tissue products exhibited the best wound healing probability (<i>p</i>-score = 0.90), followed by skin substitutes with living cells (<i>p</i>-score = 0.70), acellular skin substitutes (<i>p</i>-score = 0.56), and advanced topical dressings (<i>p</i>-score = 0.34) compared with standard of care. The recurrence analysis showed significant improvement in the intervention group compared with the control group (11.21% vs. 15.15%). <b>Future Directions:</b> This network meta-analysis provides the relative effectiveness and rank of biomaterials and topical dressings in DFU healing. The results could help clinical decision making.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"97-113"},"PeriodicalIF":4.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10008136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Tissue Oxygenation Flow-Based Index Toward Discerning the Healing Status in Diabetic Foot Ulcers.","authors":"Kevin Leiva, Alexander Trinidad, Isabella Gonzalez, Aliette Espinosa, Thomas Zwick, Jason Edward Levine, Magaly Adelaida Rodriguez, Hadar Lev-Tov, Wensong Wu, Robert S Kirsner, Anuradha Godavarty","doi":"10.1089/wound.2022.0170","DOIUrl":"10.1089/wound.2022.0170","url":null,"abstract":"<p><p><b>Objective:</b> The objective of this study is to characterize breath-hold (BH)-induced oxygenation changes in diabetic foot ulcers (DFUs) and develop an oxygenation flow index (OFI) to discern nonhealing from healing DFUs. <b>Approach:</b> The imaging approach utilizes an innovative BH stimulus that induces vasoconstriction and measures for altering oxygenation flow in and around the tissues of DFUs and controls. The modified Beer-Lambert law was utilized to calculate hemoglobin-based spatiotemporal oxygenation maps in terms of oxygen saturation. <b>Results:</b> We found controls had synchronous BH-induced oxygenation changes across the dorsal (OFI: 29.0%) and plantar (OFI: 57.6%) aspects of the foot. Nonhealing DFUs, however, had less synchronous BH-induced oxygenation changes (OFI <28%). In addition, two complicated healing DFU cases, or cases with underlying issues or poor long-term healing outcomes, were observed to have OFIs <28%. <b>Innovation:</b> An OFI was developed to differentiate nonhealing DFUs from healing DFUs using a single, noncontact, near-infrared optical scanner for spatiotemporal oxygenation monitoring. The OFI has potential to provide immediate feedback on the microcirculation in DFUs, through hemoglobin-based oxygenation parameters. <b>Conclusion:</b> A preliminary threshold (OFI <28%) could differentiate nonhealing and complicated DFUs from healing DFUs. The overall oxygenation flow pattern was less synchronous (or the OFI value reduced) in the nonwound areas of the feet that were nonhealing. In other words, the reduced OFI value (<28%) in the entire foot, excluding the wound region is a possible indicator that the wound may not heal.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"22-33"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9503485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound Biofilm Infection.","authors":"Rodney K Chan, Kristo Nuutila, Shomita S Mathew-Steiner, Victoria Diaz, Kristin Anselmo, Maria Batchinsky, Anders Carlsson, Nandini Ghosh, Chandan K Sen, Sashwati Roy","doi":"10.1089/wound.2023.0007","DOIUrl":"10.1089/wound.2023.0007","url":null,"abstract":"<p><p><b>Objective:</b> Despite advances in the use of topical and parenteral antimicrobial therapy and the practice of early tangential burn wound excision to manage bacterial load, 60% of the mortality from burns is attributed to bacterial biofilm infection. A low electric field (∼1 V) generated by the novel FDA-cleared wireless electroceutical dressing (WED) was previously shown to significantly prevent and disrupt burn biofilm infection in preclinical studies. Based on this observation, the purpose of this clinical trial was to evaluate the efficacy of the WED dressing powered by a silver-zinc electrocouple in the prevention and disruption of biofilm infection. <b>Approach</b>: A prospective, randomized, controlled, single-center clinical trial was performed to evaluate the efficacy of the WED compared with standard-of-care (SoC) dressing to treat biofilms. Burn wounds were randomized to receive either SoC or WED. Biopsies were collected on days 0 and 7 for histology, scanning electron microscopy (SEM) examination of biofilm, and for quantitative bacteriological analyses. <b>Results:</b> In total, 38 subjects were enrolled in the study. In 52% of the WED-treated wounds, little to no biofilm could be detected by SEM. WED significantly lowered or prevented increase of biofilm in all wounds compared with the pair-matched SoC-treated wounds. <b>Innovation:</b> WED is a simple, easy, and rapid method to protect the wound while also inhibiting infection. It is activated by a moist environment and the electrical field induces transient and micromolar amounts of superoxide anion radicals that will prevent bacterial growth. <b>Conclusion:</b> WED decreased biofilm infection better compared with SoC. The study was registered in clinicaltrials.gov as NCT04079998.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"1-13"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9322003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs.","authors":"Amit Gefen, Paulo Alves, Dimitri Beeckman, Breda Cullen, José Luis Lázaro-Martínez, Hadar Lev-Tov, Bijan Najafi, Nick Santamaria, Andrew Sharpe, Terry Swanson, Kevin Woo","doi":"10.1089/wound.2021.0173","DOIUrl":"10.1089/wound.2021.0173","url":null,"abstract":"<p><p><b>Significance:</b> Wounds of all types remain one of the most important, expensive, and common medical problems, for example, up to approximately two-thirds of the work time of community nurses is spent on wound management. Many wounds are treated by means of dressings. The materials used in a dressing, their microarchitecture, and how they are composed and constructed form the basis for the laboratory and clinical performances of any advanced dressing. <b>Recent Advances:</b> The established structure/function principle in material science is reviewed and analyzed in this article in the context of wound dressings. This principle states that the microstructure determines the physical, mechanical, and fluid transport and handling properties, all of which are critically important for, and relevant to the, adequate performances of wound dressings. <b>Critical Issues:</b> According to the above principle, once the clinical requirements for wound care and management are defined for a given wound type and etiology, it should be theoretically possible to translate clinically relevant characteristics of dressings into physical test designs resulting specific metrics of materials, mechanical, and fluid transport and handling properties, all of which should be determined to meet the clinical objectives and be measurable through standardized bench testing. <b>Future Directions:</b> This multidisciplinary review article, written by an International Wound Dressing Technology Expert Panel, discusses the translation of clinical wound care and management into effective, basic engineering standard testing requirements from wound dressings with respect to material types, microarchitecture, and properties, to achieve the desirable performance in supporting healing and improving the quality of life of patients.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"34-52"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41094795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of an AI-Powered Application Across Different Mobile Devices for Assessment of Chronic Wounds.","authors":"Mark Swerdlow, Jessica Lo, David G Armstrong","doi":"10.1089/wound.2022.0095","DOIUrl":"10.1089/wound.2022.0095","url":null,"abstract":"<p><p><b>Objective:</b> Evaluate the inter- and intrarater reliability of a wound assessment tool in iPhone 12 and 13 mini modalities against a validated iPad mini/Structure Sensor configuration. <b>Approach:</b> We assessed a wound measurement application (eKare inSight^®) for result consistency in patients presenting with wounds. Assessments were analyzed using a two-way analysis of variance. Intraclass correlation coefficient (ICC) was computed for intrarater (ICC_1,1) and inter-rater (ICC_2,1) analysis using a two-way random effects model. Paired <i>t</i>-test assessed the statistical difference between measurement methods. <b>Results:</b> Forty-two lesions were analyzed with surface areas ranging from 0.2 to 23 cm² (average 4.33 ± 5.44 cm²). A high level of reliability was observed for repeat wound area measurements by the same examiner (ICC_1,1 = 0.997) and between examiners with iPhone 13 mini (ICC_2,1 = 0.998). There was no significant difference between iPhone 12 and iPad mini/Structure Sensor (<i>p</i> = 0.78) or between iPhone 13 mini and iPhone 12 (<i>p</i> = 0.22). Minimal difference existed between iPhone 13 mini and iPad mini/Structure Sensor (<i>p</i> = 0.049, Cohen's <i>d</i> = 0.01). <b>Innovation:</b> Increased pervasiveness of smartphones in clinical care, coupled with advances in smartphone imaging and machine learning, allows for a potential solution to the problem of fast and accurate wound measurements. The application investigated produces wound measurement results quickly and with demonstrated accuracy. It does not require a calibration sticker or reference marker and allows for automatic wound boundary delineation. <b>Conclusion:</b> The results of this study suggest that a digital planimetry mobile application may offer high levels of reliability across devices and users.</p>","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" ","pages":"14-21"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11071090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9207705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgment of Reviewers 2023","authors":"","doi":"10.1089/wound.2023.29004.ack","DOIUrl":"https://doi.org/10.1089/wound.2023.29004.ack","url":null,"abstract":"","PeriodicalId":7413,"journal":{"name":"Advances in wound care","volume":" 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139392394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}