Maternal health, neonatology and perinatology最新文献

{"title":"Correction: Development and validation of a nomogram for predicting neonatal acute kidney injury in very low birth weight infants.","authors":"Erika Hidawa, Ryuichiro Araki, Tetsuya Kunikata, Yuko Akioka","doi":"10.1186/s40748-025-00247-2","DOIUrl":"10.1186/s40748-025-00247-2","url":null,"abstract":"","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"48"},"PeriodicalIF":0.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12723916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145812371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory distress in neonates with gestational age ≥ 35 weeks and associations between risk factors & respiratory distress.","authors":"Sarfrazul Abedin, Khalil Mohd Khalil Salameh, Anvar Paraparambil Vellamgot, Hakem S A Nazdaf, Fawzia Mohamed Abdelmoaty Soliman Elgharbawy, Adnan Muhammad Al Saeed, Rajesh Pattu Valappil, Hosame Ahmad Sharaf Eddin, Naser Abulgasim Mohamed, Abedalkhalk Ahmad Khedr, Lina Hussain M Habboub","doi":"10.1186/s40748-025-00243-6","DOIUrl":"10.1186/s40748-025-00243-6","url":null,"abstract":"<p><p>BACKGROUND: This study aimed to determine the incidence of respiratory distress among neonates ≥ 35 weeks gestational age requiring respiratory support and identify associated risk factors. METHODS: A retrospective study at Al Wakra Hospital, Qatar, from January to December 2022, included neonates born at 35 weeks or later admitted to the NICU with respiratory distress requiring support. RESULTS: During the study period, a total of 1194 out of 5637 (21.2%) neonates were admitted to the NICU for various reasons, of which 1062 (18.8%) were born at ≥ 35 weeks of gestational age. Among them, 485/5637 (8.6%) neonates were admitted to the NICU for respiratory distress and received respiratory support, with 442/5637 (7.84%) neonates included in the final analysis after applying the inclusion and exclusion criteria. The incidence of respiratory distress was highest in 35 weeks, with a progressive decline up to 39 weeks, followed by an increase. On adjusted analysis, significant predictors for respiratory distress included gestational age, cesarean delivery, instrument use, sex, fetal distress, meconium-stained liquor, 5-minute Apgar score, and resuscitation. CONCLUSIONS: Respiratory distress is a common cause of NICU admission among neonates with a gestational age of ≥ 35 weeks (8.6%). The incidence of respiratory distress was highest at 35 weeks, with a progressive decline up to 39 weeks, followed by an increase. Therefore, if possible, delaying delivery up to 39 weeks could be a good strategy to reduce respiratory distress in neonates with a gestational age of ≥ 35 weeks. </p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"47"},"PeriodicalIF":0.0,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12687543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of oral sesame oil gelatin capsules on episiotomy pain in primiparous women: a triple-blind randomized controlled trial.","authors":"Mahdis Mehrabi Bardar, Maryam Omidi, Golnaz Sadat Ahmadinezhad, Somayeh Arasteh, Roshanak Salari, Fatemeh Zahra Karimi","doi":"10.1186/s40748-025-00242-7","DOIUrl":"10.1186/s40748-025-00242-7","url":null,"abstract":"<p><p>BACKGROUND: Non-steroidal anti-inflammatory drugs are common treatments to reduce episiotomy pain intensity. Due to the side effects of these drugs, the use of medicinal plants has gained attention. In addition to pain reduction, the fatty acids in sesame oil can increase the pain perception threshold and effectively reduce episiotomy pain intensity. This study aimed to investigate the effect of sesame oil on episiotomy pain intensity in primiparous women. METHODS: This three-blind randomized controlled clinical trial was conducted on 88 primiparous women at Bent Al-Hadi Hospital in Bojnord, Iran. Participants were recruited from December 2022 to February 2024. Women meeting inclusion criteria, 2 h after vaginal delivery, received a sesame oil gelatin capsule or placebo every 6 h for 24 h. Episiotomy pain intensity was assessed before the first intervention and one hour after each dose using a visual pain scale. Data analysis was conducted using SPSS software (version 25) with independent t-tests, Mann-Whitney, and chi-square tests. A p-value of less than 0.05 was considered significant. RESULTS: Before the first intervention, the average episiotomy pain intensity score was 5.88 ± 1.13 in the sesame oil group and 5.80 ± 1.12 in the placebo group (P = 0.74).The average pain intensity score one hour after the first dose (P = 0.92) and the second dose (P = 0.64) showed no statistical significance. However, the average pain intensity score one hour after the third dose (P = 0.038) and fourth dose (P = 0.029) in the sesame oil group was significantly lower than the placebo group. CONCLUSION: Although at the start of the study and after the initial two doses, there was no significant difference between the group that received sesame oil and the group that received the placebo. However, with continued use and after the third and fourth doses, the reduction in pain within the group that took the sesame oil capsules was noticeably greater than in the placebo group. This finding y indicates that the analgesic effect of sesame oil may require time to accumulate in the body and become evident with prolonged use. </p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"46"},"PeriodicalIF":0.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12683881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145703062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and determinants of macrosomia in low- and middle-income countries: a multilevel analysis of population survey data from 44 nations.","authors":"Oumer Abdulkadir Ebrahim, Kusse Urmale Mare, Kebede Gemeda Sabo, Abdulkerim Hassen Moloro, Begetayinoral Kussia Lahole, Setognal Birara Aychiluhm, Habtamu Solomon Demeke, Beriso Furo Wengoro","doi":"10.1186/s40748-025-00241-8","DOIUrl":"10.1186/s40748-025-00241-8","url":null,"abstract":"<p><p>BACKGROUND: Although excessive birth weight is associated with short-term and long-term effects for both neonates and mothers, there is a gap in our understanding of its prevalence and contributing factors in low- and middle-income countries. Moreover, previous studies primarily focused on low birth weight and were limited to a specific geographic area. Therefore, this study aimed to estimate the prevalence of macrosomia and identify its determinants using data from 44 countries. METHODS: Data were obtained from demographic and health surveys conducted between 2015 and 2022 across 44 LMICs and a weighted total of 343,898 birth records was included in the analysis. Mixed-effect logistic regression models were fitted to identify determinants of excessive birth weight and the models were compared based on log-likelihood and deviance values. A p-value less than 0.05 and an adjusted odds ratio with the corresponding 95% confidence interval were used to identify determinants of macrosomia. RESULTS: The overall prevalence of excessive birth weight among neonates in LMCs was 7.1% [95% CI: 6.1%-8.1%], varying from 1.3% in India to 27% in Chad. The odds of excessive birth weight were higher in neonates born to mothers from households without health insurance [AOR (95% CI): 1.50 (1.36–1.65)], mothers with primary education [AOR (95% CI): 1.19 (1.09–1.31)], those born to multipara [AOR (95% CI): 1.13 (1.04–1.24), grand multipara [AOR (95% CI): 1.36 (1.20–1.54)], and overweight or obese mother [AOR (95% CI): 1.54 (1.44–1.66)]. Moreover, maternal age, number of antenatal care visits, sex of neonate, place of residence, and region were the other determinants of macrosomia. CONCLUSION: About 7% of neonates in low- and middle-income countries had excessive weight at birth, with a significant variation across the countries. Therefore, strengthening programs aimed at improving maternal literacy and promoting healthy weight management before and during pregnancy is crucial. Moreover, improving access to antenatal care and health insurance and developing programs that address the specific needs of at-risk populations, such as older, multiparous, and rural women could help reduce the incidence of macrosomia. </p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"45"},"PeriodicalIF":0.0,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior abdominal wall agenesis associated with cardiac exstrophy and macrocephaly in a gold mining area of the Democratic Republic of the Congo: management and prognosis in a resource-limited area.","authors":"Etienne Kajibwami Birindwa, Rodrigue Noko Magene, Paterne Safari Mudekereza, Jules Mongane Irenge, Cyril Nyakadere Iragi, Christophe Kyembwa Munyumbi, Blandine Bulambo Asoka, Fabrice Gulimwentuga Cikomola, Patrick de Marie Katoto Cimusa, Benoit Nemery, Théophile Kabesha Amani B, Tony Shindano Akilimali, Gloire Mubake Wabulakombe, Guy Mulinganya Mulumeoderhwa, Dieudonné Sengeyi Mushengezi Amani","doi":"10.1186/s40748-025-00237-4","DOIUrl":"10.1186/s40748-025-00237-4","url":null,"abstract":"<p><p>BACKGROUND: Congenital malformations, which are responsible for thousands of neonatal deaths every year, are prevalent in low-resource countries. Severe birth defects are mainly multifactorial but their occurrence may be exacerbated by low socioeconomic conditions and environmental factors, especially in mining areas. CASE PRESENTATION: A male neonate delivered, at term, by caesarean section from a 23-year-old woman presented multiple malformations (cardiac exstrophy, abdominal agenesis) and died 12 h after birth. The (non-consanguineous) father was an artisanal gold miner. No genetic or further morphological testing was done due to lack of resources. DISCUSSION AND CONCLUSION: The present case of severe congenital malformation in a gold mining area of the Democratic Republic of Congo, illustrates the challenges associated with the lack of specialized antenatal and neonatal care in a resource-poor country. </p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"44"},"PeriodicalIF":0.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12676812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotic ice cream influences gut and vaginal microbiota in women at high risk of preterm birth: a randomized controlled study.","authors":"Leonora S Borum, Theda U P Bartolomaeus, Ronald F Lamont, Julie R Bagge, Lajos Markó, Christina A Vinter, Ulrike Löber, Ralf Dechend, Sofia K Forslund-Startceva, Jan S Joergensen","doi":"10.1186/s40748-025-00238-3","DOIUrl":"10.1186/s40748-025-00238-3","url":null,"abstract":"<p><strong>Background: </strong>Research into probiotic use in pregnancy typically focuses on general probiotic strains. We instead investigated the relation between intake of ice cream with vaginal commensal probiotics (L. crispatus, L. gasseri, L. jensenii, L. rhamnosus GR-1; these may govern a stable microbiota and may carry beneficial functions in the vagina), throughout pregnancy, and the impact on gut and vaginal microbiomes, in women at high risk of preterm birth.</p><p><strong>Methods: </strong>This was a randomised controlled feasibility trial where the impact on gut and vaginal microbiomes was assessed by using 16 S rRNA gene sequencing and qPCR. In total 43 pregnant women were randomized, with 29 assigned to the intervention group and 14 to the control group. Both groups provided vaginal and rectal swabs by self-sampling at gestational time points. Pregnancy outcomes were registered through hospital records, and ice cream adherence and study experience was recorded.</p><p><strong>Results: </strong>We observed statistically significant gut and vaginal Lactobacillus increase during first half of pregnancy in all women with a continued increase in the second half in women compliant with the intervention. L. crispatus was found more often in the intervention group, and L. gasseri, L. jensenii and L. rhamnosus GR-1 in the ice cream could be recovered in both rectal and vaginal samples. Finally, vaginal Prevotella spp, as well as gut Gardnerella and Atopobium spp, significantly decreased upon intervention. Adherence to the intervention varied but gradually decreased throughout the study with 30.4% displaying excellent adherence in the first time period.</p><p><strong>Conclusions: </strong>We conclude that vaginal commensal probiotics administered in ice cream can be an effective method of optimizing the vaginal and intestinal health in pregnant women at high risk of preterm birth when administered regularly. We give recommendations for future studies.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov registration number 18/27209. Date of registration 03/25/2019. Date of first enrolment 04/08/2019.</p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"43"},"PeriodicalIF":0.0,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of perinatal asphyxia among newborns in Ethiopia: a systematic review and meta-analysis of incidence and risk factors.","authors":"Birhanu Jikamo, Zewditu Denu Abdissa, Belayneh Hamdela Jena, Alemu Earsido Addila, Samson Mideksa Legesse, Tesfahun Hailemariam","doi":"10.1186/s40748-025-00240-9","DOIUrl":"10.1186/s40748-025-00240-9","url":null,"abstract":"<p><strong>Background: </strong>Perinatal asphyxia remains a leading cause of neonatal morbidity and mortality in Ethiopia, yet comprehensive and up-to-date evidence on its incidence and associated risk factors is limited. Thus, this study was conducted to identify the epidemiology of perinatal asphyxia among newborns in Ethiopia: a systematic review and meta-analysis of incidence and risk factors.</p><p><strong>Methods: </strong>This systematic review and meta-analysis was carried out based on a pre-written and registered protocol on International Prospective Register of Systematic Reviews (PROSPERO) registration number (CRD42024589974). A comprehensive search of databases was conducted from PubMed/Medline, Scopus, Web of Science, Science Direct, African Journal Online, Google Scholar, and the Wiley Online Library, Cochrane Library. Population, Intervention, Comparator, Outcome, Context, and Other factors (PICOCO) and Population, Intervention, Comparator, Outcome (PICO) framework was applied. Studies were screened, and their quality was assessed using the Newcastle-Ottawa Scale. Data were extracted into Excel and then exported to STATA version 17 for analysis. Subgroup analyses were performed to identify potential sources of heterogeneity, and meta-regression was conducted to examine the influence of study-level covariates on effect sizes. Publication bias was assessed visually using funnel plots for asymmetry and statistically using Egger's test.</p><p><strong>Results: </strong>After removing 2,815 duplicates from the initial 4,740 collected studies, the pooled incidence of prenatal asphyxia in Ethiopia was 15% (95% Confidence Interval [CI]: 12-18%, p < 0.001). The most commonly identified pooled risk factors included lack of antenatal care visits (Adjusted Odds Ratio [AOR] = 1.60; 95% CI: 1.12-2.29), rural residence (AOR = 1.56; 95% CI: 1.18-2.07), low birth weight (AOR = 2.33; 95% CI: 1.53-3.54), antepartum hemorrhage (AOR = 2.09; 95% CI: 1.12-3.90), preterm birth (AOR = 2.21; 95% CI: 1.65-2.96), and neonatal Intensive Care Unit (ICU) admission (AOR = 1.88; 95% CI: 1.09-3.25).</p><p><strong>Conclusion and recommendation: </strong>This systematic review and meta-analysis identified a high incidence of perinatal asphyxia in Ethiopia, with regional variations. Several key risk factors were found to be significantly associated with the condition. Addressing these factors is crucial for preventing birth asphyxia and improving neonatal outcomes.</p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"42"},"PeriodicalIF":0.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12670775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of non-communicable diseases on maternal and perinatal outcomes in a low resource setting.","authors":"Leevan Tibaijuka, Adeline A Boatin, Yarine Fajardo Tornes, Asiphas Owaraganise, Musa Kayondo, Hamson Kanyesigye, Esther C Atukunda, Lisa M Bebell, Francis Bajunirwe, Jean-Pierre Van Geertruyden, Yves Jacquemyn, Joseph Ngonzi","doi":"10.1186/s40748-025-00239-2","DOIUrl":"10.1186/s40748-025-00239-2","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Non-communicable diseases (NCDs) are increasingly prevalent among women of reproductive age and may pose significant risks to maternal and perinatal health. Despite their growing burden, data on their impact in low-resource settings remains limited. This study aimed to investigate the impact of pre-pregnancy NCDs on severe maternal and adverse perinatal outcomes among pregnant women admitted at Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We prospectively enrolled pregnant women admitted to the maternity ward of MRRH from July 2022 to October 2023. We consecutively included all women with one or more NCDs and next two admissions without NCDs. Baseline sociodemographic and clinical documentation of pre-pregnancy NCDs including chronic hypertension, pre-gestational diabetes, cardiac disease, chronic kidney disease, sickle cell disease, asthma, and epilepsy. Participants were followed from admission through delivery, puerperium, and post-discharge with phone calls at 2, 4, and 6 weeks, and severe maternal and adverse perinatal outcomes were documented. We compared outcomes between women with and without NCDs and performed multivariable logistic regression analyses to determine the association between NCDs and these outcomes, adjusting for potential confounders, including maternal age, gravidity, employment status, HIV serostatus and delivery mode.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We enrolled a cohort of 300 pregnant women (100 with NCDs and 200 without NCDs) with a mean age of 27.8 ± 5.9 years. Severe maternal outcomes occurred in 80/300 participants (26.7%), with a significantly higher incidence among those with NCDs (36.0%, n = 36/100) compared to those without (22.0%, n = 44/200), including maternal death (4.0%, n = 4 vs. 0.5%, n = 1), acute heart failure (7.0%, n = 7 vs. 0%), ICU admission (9.0%, n = 9 vs. 2.0%, n = 4), pulmonary embolism (4.0%, n = 4 vs. 0%) and sepsis (7.0%, n = 7 vs. 1.0%, n = 2). At least one adverse perinatal outcome occurred in most participants (52.7%, n = 158/300). Women with NCDs also experienced significantly higher rates of adverse perinatal outcomes (69.0%, n = 69/100) than those without NCDs (44.5%, n = 89/200), including miscarriage (11.0%, n = 11 vs. 1.0%, n = 2), neonatal death (11.5%, n = 9 vs. 4.5%, n = 8), and NICU admission (48.7%, n = 38 vs. 20.3%, n = 36). In multivariable analysis, having one or more pre-pregnancy NCD (adjusted odds ratio [aOR]: 2.02, 95% CI [1.10, 3.68]) and attending fewer than four antenatal care (ANC) visits (aOR: 2.25, 95% CI [1.26, 4.04]) were significantly associated with increased risk of both severe maternal and adverse perinatal outcomes (NCDs: aOR: 2.39, 95% CI [1.34, 4.26]; &lt;4 ANC visits: aOR: 1.95, 95% CI [1.12, 3.38]).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Pre-pregnancy NCDs and inadequate antenatal care are linked to severe maternal and adverse perinatal outcomes. Strengthening early identifica","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12667103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145650393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-smoker and smoker identity related to mother-identity among (pre)pregnant women before and after participating in a smoking cessation intervention.","authors":"Leonieke J Breunis, Eline Meijer, Lieke C de Jong-Potjer, Jasper V Been, Eric A P Steegers, Winifred A Gebhardt, Marlou L A de Kroon","doi":"10.1186/s40748-025-00235-6","DOIUrl":"10.1186/s40748-025-00235-6","url":null,"abstract":"<p><strong>Background: </strong>Smoking cessation during pregnancy is very important but few women succeed. Supporting change in identity (i.e. perceptions of \"who I am\") towards nonsmoking seems a promising route to smoking cessation. This study aimed to assess identity of participants of the Smoke and Alcohol Free with EHealth and Rewards (SAFER) pregnancy study and evaluate the group session on identity.</p><p><strong>Methods: </strong>This prospective, uncontrolled, before-after study was conducted in The Netherlands in 2019-2021. In the SAFER pregnancy study, prepregnant and pregnant women participated in a maximum of six group sessions, one of them focused on identity, and received access to an online platform to support smoking cessation. Biochemically validated smoking cessation was rewarded with incentives with a total value up to 185 euros.</p><p><strong>Results: </strong>Thirty-nine women participated in the intervention of whom twenty-one women in the identity session. Women who identified more strongly with other mothers ('mother group-identity') also identified more strongly with the group of non-smokers ('non-smoker group-identity'; r = 0.52, P < 0.001), and those who perceived themselves more strongly as smokers ('smoker self-identity') also identified more strongly with the group of smokers (r = 0.51, P < 0.001). Non-significant changes in identity were observed. Images about the ideal, non-smoking, future self were often related to 'relaxation and freedom', 'strength and pride' and 'motherhood'. The identity session was appreciated by participants and was felt to provide grounds for open and honest discussions about smoking in the context of being a mother.</p><p><strong>Conclusions: </strong>Addressing non-smoker, smoker and mother identity may be a promising new route to improving interventions for smoking cessation around pregnancy. Effective interventions are needed to support identity in smoking cessation interventions, in order to help women quit smoking before and during pregnancy and to prevent postpartum relapse.</p><p><strong>Trial registration: </strong>Netherlands Trial Register: NL7493. Date registered: 4 February 2019.</p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"40"},"PeriodicalIF":0.0,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145491047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and neonatal outcomes in singleton pregnancies conceived using donor oocytes: a retrospective cohort study.","authors":"Robyn A Frankel, Alexandra Peyser, Moti Gulersen, Amanda Ferraro, Xueying Li, David Krantz, Burton Rochelson, Eran Bornstein, Randi Goldman, Christine Mullin","doi":"10.1186/s40748-025-00212-z","DOIUrl":"10.1186/s40748-025-00212-z","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to determine whether donor oocyte versus autologous oocyte use is associated with adverse maternal or neonatal outcomes in singleton live births conceived using assisted reproductive technology.</p><p><strong>Methods: </strong>This was a retrospective cohort study of singleton live births conceived using assisted reproductive technology and delivered within a tertiary-care university health system between January 2014 and August 2019. Multiple gestations and cases with missing data were excluded. Adverse maternal and neonatal outcomes were compared between live births conceived using donor versus autologous oocytes utilizing multivariate backwards-stepwise logistic regression to adjust for potential confounders. Data are presented as adjusted odds ratios (OR) with 95% confidence intervals (CI) with p <.05 considered statistically significant.</p><p><strong>Results: </strong>Among 1,015 singleton gestations, 97 (9.6%) were conceived using donor and 918 (90.4%) using autologous oocytes. Women using donor oocytes were older (42.5y vs. 35.4y, p <.001), more likely to have pre-gestational diabetes (5.2% vs. 0.7%, p =.001), more likely to utilize fresh embryo transfers, (29.9% vs. 18.9%, p =.01) and less likely to utilize PGT-A (25.8% vs. 51.3%, p <.001). A greater odds of a 5-minute APGAR score < 7 was noted among the donor oocyte group (4.1% vs. 0.9%, OR 4.64 [95% CI 1.30-14.45]). There were no other significant differences in maternal or neonatal outcomes between the two groups.</p><p><strong>Conclusions: </strong>In singleton gestations conceived using assisted reproductive technology, donor oocyte use does not appear to be associated with an increased risk of adverse maternal or neonatal outcomes. This may be reassuring for patients hoping to achieve a live birth through use of donor oocytes.</p>","PeriodicalId":74120,"journal":{"name":"Maternal health, neonatology and perinatology","volume":"11 1","pages":"39"},"PeriodicalIF":0.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}