Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience最新文献

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Poppy Seed Consumption and Oral Fluid Opioids Detection: A Classroom Demonstration of Psychopharmacological Concepts. 罂粟籽食用与口服液阿片类药物检测:精神药理学概念的课堂演示。
Shlomit Flaisher-Grinberg
{"title":"Poppy Seed Consumption and Oral Fluid Opioids Detection: A Classroom Demonstration of Psychopharmacological Concepts.","authors":"Shlomit Flaisher-Grinberg","doi":"10.59390/JWNQ5957","DOIUrl":"10.59390/JWNQ5957","url":null,"abstract":"<p><p>Psychopharmacological concepts such as pharmacokinetics, pharmacodynamics and drug interactions can be difficult to illustrate within the college classroom. In this demonstration, students consume poppy seed-containing food items, assess opioid content in their oral fluid using commercial drug test kits, and relate the findings to learned materials, its real-life applications, and relevant societal implications. This demonstration can clarify processes such as drug absorption, distribution, metabolism, and excretion (ADME), broaden the review of information relevant to opioids mechanisms of action, and facilitate the discussion of topics such as drug abuse, dependence, and addiction, as well as drug development, testing, policy, and enforcement. Instructors can employ different experimental designs, create dose-dependent/timeline detection plots, or allow students to construct their own experiments, assessing possible mediators of opioid detection. The demonstration can also be utilized to discuss scientific myths, truths, data misinterpretation and misrepresentation. Several optional protocols are provided, required materials are indicated, and discussion points are suggested.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A37-A44"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PopScience: Teaching students to Communicate Scientific Findings to the General Public. PopScience:教学生向公众传播科学发现。
Margaret J Gill
{"title":"PopScience: Teaching students to Communicate Scientific Findings to the General Public.","authors":"Margaret J Gill","doi":"10.59390/KCBV9244","DOIUrl":"10.59390/KCBV9244","url":null,"abstract":"<p><p>Scientific communication has become more important than ever before, yet most scientists are not trained in how to communicate their research findings to the general public. The PopScience assignment is a semester-long writing and oral communication project that focuses on how to communicate primary scientific literature to the general public. The overall goals of the PopScience project are to teach students how to: 1) critically evaluate neuroscience primary literature, and 2) translate and convey primary literature findings to a lay audience. Students completed a pre- and post- assignment perceptive assessment to evaluate the skills they obtained (e.g., reading comprehension and critical thinking), and the effectiveness of the assignment in improving these skills. Students reported that overall, the assignment improved their ability to read primary literature articles and explain them to a lay audience. Self-evaluation and professor assessments suggest the PopScience assignment also improved student's ability to integrate and summarize results from multiple sources, as well as identify and explain neuroscience terminology that often leads to confusion for lay audiences. In conclusion, this assignment teaches students how to communicate basic neuroscience to the general public, a skill that continues to be critical in successful scientific careers.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A14-A21"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Drosophila Two-Choice Assay to Study Optogenetics in Hands-On Neurobiology Laboratory Activities. 在动手神经生物学实验室活动中使用果蝇双选法研究光遗传学。
Zhuo Fu, Ainul Huda, Ian F Kimbrough, Lina Ni
{"title":"Using <i>Drosophila</i> Two-Choice Assay to Study Optogenetics in Hands-On Neurobiology Laboratory Activities.","authors":"Zhuo Fu, Ainul Huda, Ian F Kimbrough, Lina Ni","doi":"10.59390/SDWH9124","DOIUrl":"10.59390/SDWH9124","url":null,"abstract":"<p><p>Optogenetics has made a significant impact on neuroscience, allowing activation and inhibition of neural activity with exquisite spatiotemporal precision in response to light. In this lab session, we use fruit flies to help students understand the fundamentals of optogenetics through hands-on activities. The CsChrimson channelrhodopsin, a light-activated cation channel, is expressed in sweet and bitter sensory neurons. Sweet sensory neurons guide animals to identify nutrient-rich food and drive appetitive behaviors, while bitter sensory neurons direct animals to avoid potentially toxic substances and guide aversive behavior. Students use two-choice assays to explore the causality between the stimulation activation of these neurons and the appetitive and avoidance behaviors of the fruit flies. To quantify their observations, students calculate preference indices and use the Student's t-test to analyze their data. After this lab session, students are expected to have a basic understanding of optogenetics, fly genetics, sensory perception, and how these relate to sensory-guided behaviors. They will also learn to conduct, quantify, and analyze two-choice behavioral assays.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A45-A50"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unlocking Hidden Awareness: Repurposing fMRI to Detect Levels of Consciousness. 解开隐藏的意识:重新利用 fMRI 检测意识水平。
Alessia Caccamo, Gwyn Nolde, Halle Bakir, Lauren Ho, Marta C Alonso-Moreno, Sadali Wanniarachchi
{"title":"Unlocking Hidden Awareness: Repurposing fMRI to Detect Levels of Consciousness.","authors":"Alessia Caccamo, Gwyn Nolde, Halle Bakir, Lauren Ho, Marta C Alonso-Moreno, Sadali Wanniarachchi","doi":"10.59390/ZWBM2077","DOIUrl":"10.59390/ZWBM2077","url":null,"abstract":"<p><p>Determining the state of consciousness in patients with disorders of consciousness is a challenging task because for someone to be deemed conscious, both wakefulness and awareness are required. Awareness has traditionally been assessed by examining physical responsiveness but in 2010, Monti et al. explored how using fMRI to measure brain activity in humans could help reclassify the state of consciousness in these patients. The findings, published in <i>The New England Journal of Medicine</i>, show that some brain regions are active when patients respond to an imagery or communication task. This is a seminal study because it demonstrates that patients who behaviourally appear to be in a vegetative or minimally conscious state may still have residual brain functions that would not be apparent from a clinical examination alone. Notably, it exemplified how fMRI can be repurposed as a communication tool for this subset of aware, but 'locked in', patients who appear unresponsive. From an educator's perspective, this paper is valuable because it is relevant to a broad audience, both introductory and advanced level undergraduate students. It introduces key concepts in cognitive and clinical neuroscience and encourages students to consider the connections between social issues and technology development in neuroscience. Finally, educators may use this paper to discuss and debate the nature of consciousness and the ethical implications that the use of fMRI for determining consciousness may have on medical ethics.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"R6-R8"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Teaching Synaptic Transmission Using Primary Literature: A Skills-Focused Pedagogical Approach. 利用原始文献教授突触传递:以技能为重点的教学方法。
Andrew J Payne, Kyle B Bills, Scott C Steffensen
{"title":"Teaching Synaptic Transmission Using Primary Literature: A Skills-Focused Pedagogical Approach.","authors":"Andrew J Payne, Kyle B Bills, Scott C Steffensen","doi":"10.59390/NYOR9047","DOIUrl":"10.59390/NYOR9047","url":null,"abstract":"<p><p>Neuroscience is a burgeoning and intensive undergraduate major at many institutions of higher education and several areas in neuroscience education need further development. One such needed development is an increased focus on the procurement of career-relevant skills in addition to the traditional acquisition of subject knowledge. Skill development is particularly challenging in neuroscience education as the subject's interdisciplinary nature provides an atypically broad range of potential careers for graduates. Skills common to many careers in neuroscience include the ability to understand and analyze quantitative data and to draw conclusions based on those analyses. Here is presented an active learning pedagogical approach involving the analysis of seminal articles in the primary scientific literature to provide practice in analyzing data and drawing conclusions from those data while at the same time learning the fundamental tenets of synaptic transmission. Articles were selected that highlight principles such as the role of Ca<sup>2+</sup> in synaptic release, exocytosis, quantal release, and synaptic delay. Figures from these articles that can readily be used to teach these principles were selected, and questions that can help to guide students' analysis of the data are also suggested. Activities like this are needed in greater numbers to facilitate the process of helping students gain skills relevant to a productive career in neuroscience.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"R1-R5"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early-Career Pedagogical Practice: The Value of Training Undergraduates to Teach. 早期教育实践:培训本科生从事教学工作的价值。
Chandler E G Carr, Kira Bailey
{"title":"Early-Career Pedagogical Practice: The Value of Training Undergraduates to Teach.","authors":"Chandler E G Carr, Kira Bailey","doi":"10.59390/XYFR3420","DOIUrl":"10.59390/XYFR3420","url":null,"abstract":"<p><p>Pedagogical experiences prior to a career in higher education are limited, particularly for interested undergraduates. We detail here the experience of an undergraduate mentored in pedagogical techniques such as topic and reading selection, assessment creation and grading, and classroom management. Their pedagogical training included co-instructing a course with their mentor. The mentee found the experience to be rewarding, learning the areas in which they excelled and struggled. For the mentor, this was a valuable opportunity to reflect on their own pedagogical choices and techniques. The process provided a new perspective for each of us as we viewed the course through the lens of the other person. More opportunities for undergraduates to undertake similar roles may strengthen teaching in higher education and grant early career experiences to interested individuals. Though rewarding, course construction and implementation is time-consuming and difficult. Balancing time and effort beyond the class is a required skill, and frequent communication between the mentee and mentor is necessary.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A22-A26"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Insomnia Cause Revenge Seeking Behavior? Using a Puzzle-Based Sleep Lab Educational Escape Room to Teach Circadian Rhythms in a Large Introductory Neuroscience Course. 失眠会导致报复行为吗?在大型神经科学入门课程中使用基于益智的睡眠实验室教育逃生室教授昼夜节律。
Boris Nakashyan, Erin B D Clabough
{"title":"Does Insomnia Cause Revenge Seeking Behavior? Using a Puzzle-Based Sleep Lab Educational Escape Room to Teach Circadian Rhythms in a Large Introductory Neuroscience Course.","authors":"Boris Nakashyan, Erin B D Clabough","doi":"10.59390/ZGTH8157","DOIUrl":"10.59390/ZGTH8157","url":null,"abstract":"<p><p>Traditional large lecture classes can be passive experiences for students. Instead, imagine that several of those learners work at a sleep laboratory and admit four new patients. Within hours, the entire facility is on lockdown, and a mysterious voice on the intercom proclaims that all researchers will lose their ability to sleep within the next hour. This story is the plot of an interactive educational escape room (EER) where students work together and apply concepts related to the history of sleep research, circadian rhythms, and neurological concepts of sleep to solve puzzles. Conventionally, escape rooms are an entertainment experience that requires participants to escape a room in a limited timeframe. We have created a neuroscience EER designed to educate students about the neural basis of sleep, while providing small groups of students with an immersive and interactive experience. Students follow a specially designed digital escape room framework to review sleep pathways, researchers, and brain regions involved with sleep. Unlike conventional escape rooms that can accommodate a limited number of participants, this sleep lab EER is scalable to hundreds of students without the need for a specialized room. Puzzles are enhanced by digital technology that allows instructors to track the progress of every team and note how the entire classroom is doing. Students and teaching assistants had very positive experiences with this EER activity, reporting that the EER solidified course concepts while using creativity, collaboration, and critical thinking skills. We find that EERs are an easy, useful tool to increase engagement and boost inclusivity within large classroom settings, with potential to also be used as an assessment tool.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A27-A36"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reducing Brain Injury Misconceptions and Willingness to Risk Concussion with a Three-Week Introductory-level Neuroscience Course. 通过为期三周的神经科学入门课程,减少脑损伤误解,降低脑震荡风险意愿。
Rupa Gupta Gordon
{"title":"Reducing Brain Injury Misconceptions and Willingness to Risk Concussion with a Three-Week Introductory-level Neuroscience Course.","authors":"Rupa Gupta Gordon","doi":"10.59390/LEAF8930","DOIUrl":"10.59390/LEAF8930","url":null,"abstract":"<p><p>Misconceptions of brain injury are common and persistent in the general public (Ralph and Derbyshire, 2013). Moreover, undergraduate students are in an age range where they are at high risk of concussion and traumatic brain injury, but often lack knowledge of the symptoms, severity, recovery, and varied impacts of brain injury on cognition. Introductory-level undergraduate neuroscience courses have the potential to reach a broad audience and improve students' knowledge of the brain. It is also important to know, however, if neuroscience courses can combat common misconceptions and impact real-world behaviors like willingness to risk concussion and prevention of brain injury. An introductory-level immersive three-week course during January term was developed, targeted at first-year students and non-majors. The focus of the course was to help students understand the role of different brain regions in behavior by presenting neurological cases that demonstrate the human experience of brain injury. Following the course, all students displayed greater knowledge about brain injury and reduced willingness to risk brain injury or concussion. Although students with a history of concussion were more willing to risk future concussion overall, they did show a similar reduction in risk as those without a history of concussion but were also less likely to endorse safety practices like helmet use. Beyond improving basic knowledge of neuroscience, introductory-level courses also have an opportunity to impact students' understanding of brain injury in their personal and professional lives.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"22 1","pages":"A51-A57"},"PeriodicalIF":0.0,"publicationDate":"2023-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139699041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Undergraduate Laboratory Series Using C. elegans That Prepares Students for Independent Inquiry. 使用秀丽隐杆线虫的本科生系列实验,为学生独立探究做好准备。
Virginia Quinan, Kelly Hsu, Molly Mann, Kia Barclay, Deborah Bauer
{"title":"An Undergraduate Laboratory Series Using <i>C. elegans</i> That Prepares Students for Independent Inquiry.","authors":"Virginia Quinan, Kelly Hsu, Molly Mann, Kia Barclay, Deborah Bauer","doi":"10.59390/XPYK3682","DOIUrl":"10.59390/XPYK3682","url":null,"abstract":"<p><p>Undergraduate neuroscience laboratories provide valuable opportunities for students to learn about neurobiological systems through active learning. <i>Caenorhabditis elegans</i> (<i>C. elegans</i>) is a valuable model for teaching students how to use a reductionist approach to neuroscientific inquiry. This series of lab modules trains students to utilize foundational laboratory techniques such as worm handling and maintenance, fluorescence imaging, behavioral assays, and Western blot. Upon completing this series of laboratory exercises, students are well prepared to engage in independent research projects using these research techniques. As supported by student survey results, this series of <i>C. elegans</i> laboratory exercises leads to the development of essential research skills, which students may be able to apply to a wide range of future scientific endeavors.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"21 2","pages":"A133-A141"},"PeriodicalIF":0.0,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426820/pdf/june-21-133.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10126514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Student Performance in Emergency Remote and Face-to-Face Collaborative Learning Courses. 比较学生在应急远程和面对面协作学习课程中的表现。
Yasmin Azizi, John Hession, Thomas M Newpher
{"title":"Comparing Student Performance in Emergency Remote and Face-to-Face Collaborative Learning Courses.","authors":"Yasmin Azizi, John Hession, Thomas M Newpher","doi":"10.59390/AXNC2524","DOIUrl":"10.59390/AXNC2524","url":null,"abstract":"<p><p>The start of the COVID-19 pandemic forced an unprecedented shift from face-to-face (F2F) instruction to emergency remote teaching (ERT) for over one billion learners worldwide. Studies from K-12 and higher education have begun to address the impact of ERT on student learning and well-being. The lessons learned from ERT will likely shape the response to future public health emergencies and inform the design and implementation of remote courses. As such, it will be important to identify teaching practices in ERT that promoted student engagement and learning. Here, we address whether undergraduate collaborative learning courses were able to support student content knowledge outcomes at similar levels in ERT as compared to F2F classroom environments. Specifically, we tracked student performance in three different team-based undergraduate neuroscience courses. These courses were all taught by the same instructor during the academic years 2020-2021 and 2021-2022. Importantly, we found that student scores on individual and team assessments as well as measures of course satisfaction were similar between ERT and F2F. Taken together, our data suggest that the virtual collaborative learning environment in these courses was not associated with a decrease in student or team performance when compared to a traditional F2F classroom.</p>","PeriodicalId":74004,"journal":{"name":"Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience","volume":"21 2","pages":"A126-A125"},"PeriodicalIF":0.0,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426814/pdf/june-21-117.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10135575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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