Journal of the International Society for Respiratory Protection最新文献_第4页

Fit Assessment of N95 Filtering-Facepiece Respirators in the U.S. Centers for Disease Control and Prevention Strategic National Stockpile. 美国疾病控制和预防中心国家战略储备中N95过滤面罩的适用性评估。

Journal of the International Society for Respiratory Protection Pub Date : 2015-01-01

Michael Bergman, Ziqing Zhuang, Elizabeth Brochu, Andrew Palmiero

{"title":"Fit Assessment of N95 Filtering-Facepiece Respirators in the U.S. Centers for Disease Control and Prevention Strategic National Stockpile.","authors":"Michael Bergman, Ziqing Zhuang, Elizabeth Brochu, Andrew Palmiero","doi":"","DOIUrl":"","url":null,"abstract":"National Institute for Occupational Safety and Health (NIOSH)-approved N95 filtering-facepiece respirators (FFR) are currently stockpiled by the U.S. Centers for Disease Control and Prevention (CDC) for emergency deployment to healthcare facilities in the event of a widespread emergency such as an influenza pandemic. This study assessed the fit of N95 FFRs purchased for the CDC Strategic National Stockpile. The study addresses the question of whether the fit achieved by specific respirator sizes relates to facial size categories as defined by two NIOSH fit test panels. Fit test data were analyzed from 229 test subjects who performed a nine-donning fit test on seven N95 FFR models using a quantitative fit test protocol. An initial respirator model selection process was used to determine if the subject could achieve an adequate fit on a particular model; subjects then tested the adequately fitting model for the nine-donning fit test. Only data for models which provided an adequate initial fit (through the model selection process) for a subject were analyzed for this study. For the nine-donning fit test, six of the seven respirator models accommodated the fit of subjects (as indicated by geometric mean fit factor > 100) for not only the intended NIOSH bivariate and PCA panel sizes corresponding to the respirator size, but also for other panel sizes which were tested for each model. The model which showed poor performance may not be accurately represented because only two subjects passed the initial selection criteria to use this model. Findings are supportive of the current selection of facial dimensions for the new NIOSH panels. The various FFR models selected for the CDC Strategic National Stockpile provide a range of sizing options to fit a variety of facial sizes.","PeriodicalId":73984,"journal":{"name":"Journal of the International Society for Respiratory Protection","volume":"32 2","pages":"50-64"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72212195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MS2 Coliphage as a Surrogate for 2009 Pandemic Influenza A (H1N1) Virus (pH1N1) in Surface Survival Studies on N95 Filtering Facepiece Respirators. 在 N95 过滤面罩呼吸器表面存活率研究中将 MS2 Coliphage 作为 2009 年甲型 (H1N1) 流感大流行病毒 (pH1N1) 的替代物。

Journal of the International Society for Respiratory Protection Pub Date : 2014-01-01

A D Coulliette, K A Perry, E M Fisher, J R Edwards, R E Shaffer, J Noble-Wang

{"title":"MS2 Coliphage as a Surrogate for 2009 Pandemic Influenza A (H1N1) Virus (pH1N1) in Surface Survival Studies on N95 Filtering Facepiece Respirators.","authors":"A D Coulliette, K A Perry, E M Fisher, J R Edwards, R E Shaffer, J Noble-Wang","doi":"","DOIUrl":"","url":null,"abstract":"Research on influenza viruses regarding transmission and survival has surged in the recent years due to infectious emerging strains and outbreaks such as the 2009 Influenza A (H1N1) pandemic. MS2 coliphage has been applied as a surrogate for pathogenic respiratory viruses, such as influenza, as it's safe for personnel to handle and requires less time and labor to measure virus infectivity. However, direct comparisons to determine the effectiveness of coliphage as a surrogate for influenza virus regarding droplet persistence on personal protective equipment such as N95 filtering facepiece respirators (FFRs) are lacking. Persistence of viral droplets deposited on FFRs in healthcare settings is important to discern due to the potential risk of infection via indirect fomite transmission. The objective of this study was to determine if MS2 coliphage could be applied as a surrogate for influenza A viruses for studying persistence when applied to the FFRs as a droplet. The persistence of MS2 coliphage and 2009 Pandemic Influenza A (H1N1) Virus on FFR coupons in different matrices (viral media, 2% fetal bovine serum, and 5 mg ml-1 mucin) were compared over time (4, 12, 24, 48, 72, and 144 hours) in typical absolute humidity conditions (4.1 × 105 mPa [18°C/20% relative humidity (RH)]). Data revealed significant differences in viral infectivity over the 6-day period (H1N1- P <0.0001; MS2 - P <0.005), although a significant correlation of viral log10 reduction in 2% FBS (P <0.01) was illustrated. Overall, MS2 coliphage was not determined to be a sufficient surrogate for influenza A virus with respect to droplet persistence when applied to the N95 FFR as a droplet.","PeriodicalId":73984,"journal":{"name":"Journal of the International Society for Respiratory Protection","volume":"21 1","pages":"14-22"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615560/pdf/nihms726712.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34286026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Filtration Performance of FDA-Cleared Surgical Masks. fda批准的医用口罩的过滤性能。

Journal of the International Society for Respiratory Protection Pub Date : 2009-02-01

Samy Rengasamy, Adam Miller, Benjamin C Eimer, Ronald E Shaffer

{"title":"Filtration Performance of FDA-Cleared Surgical Masks.","authors":"Samy Rengasamy, Adam Miller, Benjamin C Eimer, Ronald E Shaffer","doi":"","DOIUrl":"","url":null,"abstract":"Ashortage of NIOSH-approved respirators is predicted during an influenza pandemic and other infectious disease outbreaks. Healthcare workers may use surgical masks instead of respirators due to non-availability and for economical reasons. This study investigated the filtration performance of surgical masks for a wide size range of submicron particles including the sizes of many viruses. Five models of FDA-cleared surgical masks were tested for room air particle penetrations at constant and cyclic flow conditions. Penetrations of polydisperse NaCl aerosols (75±20 nm, count median diameter), monodisperse NaCl aerosols (20-400 nm range) and particles in the 20-1000 nm range were measured at 30 and 85 liters/min. Filtration performance of surgical masks varied widely for room air particles at constant flow and correlated with the penetration levels measured under cyclic flow conditions. Room air particle penetration levels were comparable to polydisperse and monodisperse aerosol penetrations at 30 and 85 liters/minute. Filtration performance of FDA-cleared surgical masks varied widely for room air particles, and monodisperse and polydisperse aerosols. The results suggest that not all FDA-cleared surgical masks will provide similar levels of protection to wearers against infectious aerosols in the size range of many viruses.","PeriodicalId":73984,"journal":{"name":"Journal of the International Society for Respiratory Protection","volume":"26 3","pages":"54-70"},"PeriodicalIF":0.0,"publicationDate":"2009-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357397/pdf/nihms-1604065.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38149508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticle Filtration Performance of Commercially Available Dust Masks. 市售防尘口罩的纳米颗粒过滤性能。

Journal of the International Society for Respiratory Protection Pub Date : 2008-02-01

Samy Rengasamy, Benjamin C Eimer, Ronald E Shaffer

{"title":"Nanoparticle Filtration Performance of Commercially Available Dust Masks.","authors":"Samy Rengasamy, Benjamin C Eimer, Ronald E Shaffer","doi":"","DOIUrl":"","url":null,"abstract":"Dust masks are often confused with filtering facepiece respirators (FFR) but are not approved by NIOSH for respiratory protection against particulate exposure. This study reports the filtration performance of commercially available dust masks against submicron particles and discusses the relevance of these findings toward the filtration of nanoparticles. Seven different models of dust masks from local home improvement/hardware stores were challenged with submicron NaCl particles, and initial percentage penetration and resistance levels were measured using two test procedures. A polydisperse aerosol test (PAT) method, similar to the \"worst case\" conditions used in the NIOSH particulate respirator certification test protocol was used. A monodisperse aerosol test (MAT) method, which utilizes eleven different particle sizes in the range of 20-400 nm, were also used for particle penetration measurements at 30 and 85 L/min flow rates using the TSI 3160. Dust masks were designated as category low-, medium- and high-penetration dust masks based on penetration levels of <5%, 5-25% and >25%, respectively. Data collected using the PAT and the MAT methods showed <5% initial penetration levels for low-penetration dust masks, which is similar to the NIOSH-approved class-95 filtering facepiece respirators. Average penetration levels for medium- and high-penetration dust masks were between 8.9-24.2% and 74.5-96.9%, respectively. Penetration levels of MPPS particles from the MAT correlated with penetration levels from the PAT. Monodisperse MPPS penetration levels from MAT and penetration levels from PAT showed poor correlation with resistance values and no correlation with cost. The results of this study show that dust masks frequently do not provide filtration performance equivalent to that of NIOSH certified devices. Users of dust masks should be cautioned against using them for protection against particulates in the nano- or ultrafine size ranges.","PeriodicalId":73984,"journal":{"name":"Journal of the International Society for Respiratory Protection","volume":"25 3","pages":"27-41"},"PeriodicalIF":0.0,"publicationDate":"2008-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357396/pdf/nihms-1604064.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38149507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0