Journal of orthopaedics and sports medicine最新文献_第2页

Outcomes of Rotator Cuff Repair: Open vs. Arthroscopic Approaches in Patients with Diabetes or Hyperlipidemia. 肩袖修复的结果：糖尿病或高脂血症患者的开放与关节镜入路

Journal of orthopaedics and sports medicine Pub Date : 2025-01-01 Epub Date: 2025-05-15 DOI: 10.26502/josm.511500201

Kevin Babakhan Vartanian, Kevin Ghookas, Tony Eskandar, Niayesh Najafi, Devendra K Agrawal

{"title":"Outcomes of Rotator Cuff Repair: Open vs. Arthroscopic Approaches in Patients with Diabetes or Hyperlipidemia.","authors":"Kevin Babakhan Vartanian, Kevin Ghookas, Tony Eskandar, Niayesh Najafi, Devendra K Agrawal","doi":"10.26502/josm.511500201","DOIUrl":"10.26502/josm.511500201","url":null,"abstract":"Rotator cuff injuries are a common cause of shoulder dysfunction, with diabetes mellitus and hyperlipidemia contributing to increased tendon vulnerability and impaired healing. In this article, a critical evaluation is presented on the comparative outcomes of open versus arthroscopic rotator cuff repair (RCR) in patients with these metabolic conditions. Findings suggest that arthroscopic RCR compared to open RCR offers advantages such as reduced tissue disruption, shorter recovery times, and lower infection rates, making it a preferred choice for metabolically compromised patients. However, open RCR provides superior visualization and structural support, as well as better function, benefiting patients with extensive tendon damage. In diabetics there was higher retear and infection rates than non-diabetics, particularly with open RCR, while those with hyperlipidemia exhibited impaired tendon healing and increased postoperative complications, with mixed effects from statin therapy. Despite these findings, existing research lacks large-scale, controlled studies directly comparing surgical outcomes in these high-risk populations. Given the chronic inflammatory and metabolic impairments associated with diabetes mellitus and hyperlipidemia, surgical decisions should be tailored to patient-specific factors, including lipid and glycemic control, tendon integrity, and tear severity. Arthroscopy appears to be the preferable option due to minimizing surgical trauma, lower retear rates and faster return-to-work times; meanwhile, open repair remains valuable in cases requiring extensive intervention.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"7 2","pages":"240-249"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Artificial Intelligence and its Subsets in Various Stages of Knee Arthroplasty from Pre-op to Post-op: An Overview. 人工智能及其子集在膝关节置换术从术前到术后各阶段的应用：概述。

Journal of orthopaedics and sports medicine Pub Date : 2025-01-01 Epub Date: 2025-03-11 DOI: 10.26502/josm.511500185

Jacqueline B Anderson Enni, Devendra K Agrawal

引用次数: 0

Energizing Healing with Electromagnetic Field Therapy in Musculoskeletal Disorders. 用电磁场疗法治疗肌肉骨骼疾病。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-05-17 DOI: 10.26502/josm.511500147

Resmi Rajalekshmi, Devendra K Agrawal

{"title":"Energizing Healing with Electromagnetic Field Therapy in Musculoskeletal Disorders.","authors":"Resmi Rajalekshmi, Devendra K Agrawal","doi":"10.26502/josm.511500147","DOIUrl":"10.26502/josm.511500147","url":null,"abstract":"There is mounting evidence to suggest that exogenous electromagnetic fields (EMF) may play a significant role in various biological processes that are crucial to therapeutic interventions. EMFs have been identified as a non-invasive, safe, and effective therapy that appears to have no apparent side effects. Numerous studies have demonstrated that pulsed EMFs (PEMFs) have the potential to become a stand-alone or adjunctive treatment modality for managing musculoskeletal disorders. However, several questions remain unresolved. Before their widespread clinical application, further research from well-designed, high-quality studies is required to standardize treatment parameters and determine the optimal protocol for healthcare decision-making. This article provides a comprehensive overview of the impact of musculoskeletal diseases on overall well-being, the limitations of conventional treatments, and the need to explore alternative therapeutic modalities such as electromagnetic field (EMF) therapy. EMF therapy uses low-frequency electromagnetic waves to stimulate tissue repair, reduce inflammation, and modulate pain signals, making it a safe and convenient alternative to conventional treatments. The article also discusses the historical perspective of EMF therapy in medicine. The article highlights the potential of EMF therapy as a personalized and comprehensive care option for musculoskeletal diseases, either alone or in conjunction with other therapies. It emphasizes the imperative for further research in this field and presents a compelling case for the use of EMF therapy in managing musculoskeletal diseases. Overall, the available findings on the underlying cellular and molecular biology support the use of EMF therapy as a viable option for the management of musculoskeletal disorders and stresses the need for continued research in this area.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 2","pages":"89-106"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammation and Fatty Infiltration Correlates with Rotator Cuff Muscle Atrophy in Hypercholesterolemic Yucatan Microswine. 炎症和脂肪浸润与高胆固醇血症尤卡坦微型猪的肩袖肌萎缩相关。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-09-16 DOI: 10.26502/josm.511500161

Hoangvi Le, Vikrant Rai, Devendra K Agrawal

{"title":"Inflammation and Fatty Infiltration Correlates with Rotator Cuff Muscle Atrophy in Hypercholesterolemic Yucatan Microswine.","authors":"Hoangvi Le, Vikrant Rai, Devendra K Agrawal","doi":"10.26502/josm.511500161","DOIUrl":"10.26502/josm.511500161","url":null,"abstract":"Rotator cuff injuries are the most common injuries among active and training astronauts. According to the CDC, 1 in 4 adults in the U.S. experience rotator cuff injuries, particularly affecting the supraspinatus muscle. Hypercholesterolemia, a condition characterized by high levels of LDL cholesterol, is prevalent in approximately 2 in 5 adults in the US and is a risk factor for worsened outcomes in shoulder inflammation and rotator cuff injury repairs. Chronic inflammation, a prolonged low-grade inflammatory state, can arise from conditions like hypercholesterolemia and contribute to muscle atrophy. Skeletal muscle atrophy can be caused by factors such as disuse, aging, malnutrition, and microgravity, and currently lacks approved drug therapies. Thus, gaining a comprehensive understanding of the associations between hypercholesterolemia, chronic inflammation, and skeletal muscle atrophy is imperative for developing effective strategies to manage this condition. We conducted an animal study in Yucatan miniswine to investigate the impact of a high-cholesterol diet on rotator cuff muscle. The results suggested the presence of chronic inflammation in rotator cuff muscle hypercholesterolemic swine, associated with elevated pro-inflammatory cytokines and intramuscular adipocytes, and skeletal muscle atrophy. The results also revealed upregulation of the FOXO3/TRIM63/Titin axis in a hyperlipidemic state. These findings open new perspectives for developing better treatment strategies by targeting the FOXO3/TRIM63/Titin axis to manage rotator cuff muscle atrophy in the context of hypercholesterolemia.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 3","pages":"198-213"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthopedic Dermatopathies: Skin Manifestations in Orthopedic Conditions. 骨科皮肤病：骨科疾病的皮肤表现。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-08-30 DOI: 10.26502/josm.511500157

Tony Eskandar, Fihr Chaudhary, Devendra K Agrawal

{"title":"Orthopedic Dermatopathies: Skin Manifestations in Orthopedic Conditions.","authors":"Tony Eskandar, Fihr Chaudhary, Devendra K Agrawal","doi":"10.26502/josm.511500157","DOIUrl":"https://doi.org/10.26502/josm.511500157","url":null,"abstract":"Orthopedic diseases often present with dermatological symptoms that require prompt identification for appropriate treatment. Understanding these dermatologic presentations is crucial for accurate diagnosis and effective management. This article critically reviewed the dermatological manifestations observed in general and regional pathologies, followed by treatment-related manifestations. An extensive literature search was performed and limited to manifestations in orthopedic disease, excluding those pertaining to infection or syndromes. Case reports and case series documenting unusual and rare dermatologic presentations of orthopedic conditions were examined, providing novel perspectives on both prevalent and uncommon illnesses. The identified pathologies are discussed in detail, including their clinical features and diagnosis, while treatment approach varies depending on the severity of the condition, ranging from self-care to surgical intervention. The findings emphasize the need for interdisciplinary collaboration and highlight the importance of careful diagnosis and appropriate management to eliminate unnecessary approaches and ensure optimal outcomes for patients with orthopedic diseases and dermatologic symptoms.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 3","pages":"171-183"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Critical Analysis of the Factors Contributing to Anterior Cruciate Ligament Injuries in Female Athletes. 对导致女性运动员前十字韧带损伤因素的批判性分析。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-10-04 DOI: 10.26502/josm.511500163

Bahram Saber, Daniel Bridger, Devendra K Agrawal

{"title":"A Critical Analysis of the Factors Contributing to Anterior Cruciate Ligament Injuries in Female Athletes.","authors":"Bahram Saber, Daniel Bridger, Devendra K Agrawal","doi":"10.26502/josm.511500163","DOIUrl":"10.26502/josm.511500163","url":null,"abstract":"Anterior Cruciate Ligament (ACL) injuries are a prevalent concern in athletic population, particularly among female athletes who are disproportionately affected. The increased incidence of ACL injuries in females is attributed to a combination of anatomical, physiological, and biomechanical factors that influence knee stability. This review comprehensively explores these contributing factors, highlighting gender-specific anatomical differences such as wider pelvis, increased quadriceps (Q) angle, and steeper tibial slopes, all of which predispose females to greater knee valgus during dynamic activities. Furthermore, hormonal influences and greater ligament laxity are discussed as physiological contributors to increased ACL injury risk. Biomechanical factors such as reduced knee flexion, increased knee valgus, and altered muscle activation patterns further amplify the risk of ACL tears in female athletes. Despite extensive research, gaps remain in the understanding of how these factors interact and influence injury susceptibility. This article is focussed on the critical points in the current literature, analyzing key risk factors, and identifying future research directions that can inform more effective prevention strategies. A better understanding of these factors will ultimately contribute to reducing the incidence of ACL injuries among female athletes and improving long-term strength and stability of knee joint.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 4","pages":"203-209"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rotator Cuff Injury: Pathogenesis, Biomechanics, and Repair. 肩袖损伤：发病机制、生物力学和修复。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-10-22 DOI: 10.26502/josm.511500167

Pallavi Sripathi, Devendra K Agrawal

{"title":"Rotator Cuff Injury: Pathogenesis, Biomechanics, and Repair.","authors":"Pallavi Sripathi, Devendra K Agrawal","doi":"10.26502/josm.511500167","DOIUrl":"10.26502/josm.511500167","url":null,"abstract":"Anterior Rotator cuff tears are one of the most common surgically addressed disorders, as the tears in the tendon can affect anyone regardless of risk factors or activity level. The rotator cuff is responsible for most of the shoulder motion, hence the tendon-bone interface experiences immense stress making it incredibly prone to failure. Rotator cuff tendon tears can either occur due to trauma or natural degeneration of the rotator cuff. To help mitigate effects of high stress on the rotator cuff tendon-bone interface, the rotator cuff is intrinsically designed to redistribute stress through protective mechanisms, such as the rotator crescent or coronal-transverse force. But when the tear goes through the intrinsic protective mechanisms, the glenohumeral joint is left unstable and thus is no longer capable of its normal range of motion. Location, size, and type of rotator cuff tendon tears are the strongest indicators for interventional therapy. Surgical therapies demonstrate low success rates, as seen by the significantly high recurrence rate of rotator cuff reinjury following initial repair. This is due to extrinsically healing of rotator cuff tendons, instead of the more intrinsic healing, which causes rotator cuff tendons to not undergo the necessary biomechanical remodeling to prevent reinjury leading to a mechanically and functionally inferior healed tendon. In this article, we thoroughly discussed the underlying pathophysiology of rotator cuff tears from onset to repair to healing, demonstrating that rotator cuff tendon healing is an intrinsically flawed process, irrespective of the risk factors, occurrence of rotator cuff tears, or surgical treatment. Rotator cuff healing can only be successful if rotator cuff tendon repair surgery is augmented with biologics to promote a successful intrinsic healing environment.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 4","pages":"231-248"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Adaptation of Achilles Tendon Tissues upon Injury to Rotator Cuff Tendon in Hyperlipidemic Swine. 高脂血症猪跟腱组织在肩袖肌腱损伤后的慢性适应。

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-05-10 DOI: 10.26502/josm.511500146

Merlin Rajesh Lal, Devendra K Agrawal

{"title":"Chronic Adaptation of Achilles Tendon Tissues upon Injury to Rotator Cuff Tendon in Hyperlipidemic Swine.","authors":"Merlin Rajesh Lal, Devendra K Agrawal","doi":"10.26502/josm.511500146","DOIUrl":"https://doi.org/10.26502/josm.511500146","url":null,"abstract":"The biomechanical properties of the tendon are affected due to the changes in composition of the tendon extracellular matrix (ECM). Age, overuse, trauma and metabolic disorders are a few associated conditions that contribute to tendon abnormalities. Hyperlipidemia is one of the leading factors that contribute to the compromised biomechanical. Injury was made on infraspinatus tendon of hyperlipidemic swines. After 8 weeks (i) infraspinatus tendon from the injury site, (ii) infraspinatus tendon from the contralateral side and (iii) Achilles tendon, were collected and analyzed for ECM components that form the major part in biomechanical properties. Immunostaining of infraspinatus tendon on the injury site had higher staining collagen type-1 (COL1A1), biglycan, prolyl 4-hydroxylase and mohawk but lower staining for decorin than the control group. The Achilles tendon of the swines that had injury on infraspinatus tendon showed a chronic adaptation towards load which was evident from a more organized ECM with increased decorin, mohawk and decreased biglycan, scleraxis. The mechanism behind the collagen turnover and chronic adaptation to load need to be studied in detail with the biomechanical properties.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"6 2","pages":"80-88"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11210446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperlipidemia Induced Pathological Changes with no Effect in Biomechanical Properties in the Achilles Tendon of Young Swine. 高脂血症诱发病理变化，但对幼猪跟腱的生物力学特性没有影响

Journal of orthopaedics and sports medicine Pub Date : 2024-01-01 Epub Date: 2024-04-22 DOI: 10.26502/josm.511500144

Merlin Rajesh Lal L P, Devendra K Agrawal

引用次数: 0

Whole Body Cryotherapy in Sport and Physical Activity: A Narrative Review 运动和身体活动中的全身冷冻疗法:述评

Journal of orthopaedics and sports medicine Pub Date : 2023-01-01 DOI: 10.26502/josm.511500102

Paolo Mario Sarais, G. Alvarez Rey, G. Boni, D. Dıraçoğlu, J. Laíns, Raimondo Leone, F. Migliore, A. Perrotta, A. Migliore

{"title":"Whole Body Cryotherapy in Sport and Physical Activity: A Narrative Review","authors":"Paolo Mario Sarais, G. Alvarez Rey, G. Boni, D. Dıraçoğlu, J. Laíns, Raimondo Leone, F. Migliore, A. Perrotta, A. Migliore","doi":"10.26502/josm.511500102","DOIUrl":"https://doi.org/10.26502/josm.511500102","url":null,"abstract":"Cold therapy application is commonly used to relieve pain symptoms, to reduce inflammation in chronic diseases and damage in injuries at the musculoskeletal level. Two types of technologies, Partial Body Cryotherapy (PBC) or Whole Body Cryotherapy (WBC), are available in the market. This narrative review reports data from trials exploring WBC in Sport and in physical activity with the aim to show limitations and effectiveness in healthy subjects performing sport activity. The systematic search was conducted on the past ten years. The search keywords were \"Whole Body Cryotherapy\" OR \"Cryogenic chamber therapy\" OR \"Cryostimulation\" AND \"Sport\" OR \"Exercise\" OR \"Athlete\" OR \"Physical Activity.\" The sample size, subject’s age and gender, year of publication, duration and temperature of exposition, physical activity and outcomes were extracted. 15 articles met the inclusion criteria. Data on 265 subjects aged between 20 to 56 years were reported. The WBC protocols covered temperatures from -20 to -120 degrees Celsius. Exposure times ranged from 1 minute to 3 minutes. The cryostimulation sessions were coupled to normal daily recreational activities or, in the case of athletes, competitive activities during the competition season. WBC is a safe procedure and no major adverse events neither alteration of vital parameters were reported. The benefits have been found especially in post-exercise DOMS. Since many aspects need to be clarified a research agenda has been produced to answer crucial questions. In conclusion WBC seems to be a useful tool in Sport Medicine. However, further studies are necessary to establish standardized protocols.","PeriodicalId":73881,"journal":{"name":"Journal of orthopaedics and sports medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69349457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0