Journal of neonatal biology最新文献

{"title":"Head to Shoulder Interval in 92 Cases Normal Birth with Good Baby Condition by Two Step Shoulder Delivery Method","authors":"Hong-yu Zhang, Y. Ling","doi":"10.4172/2167-0897.1000203","DOIUrl":"https://doi.org/10.4172/2167-0897.1000203","url":null,"abstract":"Purpose of investigation: Observation of natural process of head to shoulder interval by waiting for at least one contraction (two-step method) after head delivered in normal birth. \u0000Method: From 1st to the end of mar. In 2015 at Haikou maternal and child hospital in China, women in vaginal delivery meet the criteria were recorded by video from head crown to shoulder and to body delivered. 92 cases normal vaginal birth with normal baby condition were recorded, video tapes were transfer to computer then replayed and observed. Interval of head crown to head delivery and head to shoulder delivery, babies' activities during birth were recorded from video at same time. \u0000Result: 1. The mean time of head to shoulder interval by waiting for a contraction is (71.043 ± 61.015) sec, mean+2Std. =193.073sec, 95% CI (15.65-229.15) sec. 2. 55.43 % (51/92) percent interval of head to shoulder were less than 60 sec, 39.1% (36/92) were over 60sec and less than 190 sec. 5.4 %( 5/92) over 190 sec. 3. 71.734% (66/92) shoulders were emerged from perineum, 15.217% (14/92) transversely, 13.04% (12/92) emerged from under pubic. 4. 22 % percent babies breathed before shoulder delivery, some after, some did not cry at all, but had normal heartbeat and breath Patten. \u0000Conclusion: 1. Head to shoulder delivery interval is longer than 60 sec by two step method of shoulder delivery. The majority shoulders emerged from perineum rather from under pubic. 96.73% (89/92) cases shoulders were delivered at the first contraction after head delivered, only 3.27% (3/92) cases had delivered by twice contractions. 2. Babies activities during delivery of shoulder included breath, making faces, sucking, bubble from noses and mouth, and the color of the face, all those signs indicated the normal live birth.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2015-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70812063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing Enterocolitis (NEC): A Devastating Disease of Prematurity.","authors":"Parvesh M Garg, Padma P Garg, C. Lal","doi":"10.4172/2167-0897.1000202","DOIUrl":"https://doi.org/10.4172/2167-0897.1000202","url":null,"abstract":"Necrotizing Enterocolitis (NEC) is a common and devastating gastrointestinal emergency that primarily affects premature infants. The incidence of necrotizing enterocolitis is 6-10% among infants with birth weight less than 1500 grams. The mortality due to NEC has not improved significantly despite advances in neonatal care and better understanding of clinical and basic sciences. The pathogenesis of NEC is not well understood and several factors such as prematurity, abnormal colonization with pathogenic bacteria, feeding practices, blood transfusion and altered intestinal barrier function may be involved. The clinical presentation of NEC could be sudden and the treatment plan could vary with the stage and type of presentation. Further research is needed to better understand the pathophysiology of NEC and, biomarkers for prediction, prevention and treatment need to be developed. Further clinical trials are needed to determine prevention and treatment modalities for this devastating disease.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-Onset Neonatal Sepsis: Group B Streptococcal Compared to E. coli Disease","authors":"Renoldner B, Hofer N, Resch B","doi":"10.4172/2167-0897.1000201","DOIUrl":"https://doi.org/10.4172/2167-0897.1000201","url":null,"abstract":"Background: Early onset sepsis (EOS) of the newborn is a severe disease and associated with high morbidity and mortality. Aim of the study was to compare perinatal, short-term outcome and laboratory data of neonates with early-onset sepsis (EOS) either due to Group B Streptococci (GBS) or Escherichia coli (E. coli) infection. \u0000Methods: Retrospective cohort analysis of all neonates with culture proven GBS and E. coli EOS born between 1993 and 2011 and hospitalized at the NICU of the Medical University of Graz, Austria. Data were analyzed regarding perinatal, laboratory and short-term outcome data. \u0000Results: During the study period 100 neonates with EOS due to GBS and 11 neonates with E. coli infection were hospitalized at our NICU. Perinatal and short-term outcome data differed between GBS and E. coli infection regarding gestational age (median 38 vs. 32 weeks, p=.005), birth weight (median 3095 vs. 1836 grams, p=.031), presence of hypothermia (0 vs. 18%, p=.009), duration of mechanical ventilation (4 vs. 8 days, p=.019), duration of therapy with supplemental oxygen (9 vs. 2 days, p=.031), length of hospitalization (15 vs. 22 days, p=.039), presence of chorioamnionitis (17 vs. 46%, p=.041) and maternal fever (2 vs. 18%, p=.049). Mortality rates did not differ significantly (6 vs. 18%, p=.180). Laboratory data regarding white blood cell count, IT-ratio, and CRP value were not different between groups within the first 72 hours of life. There was a significant decrease of GBS sepsis during the study period (p=0,014). Conclusion: Main differences between GBS and E. coli infections were due to higher rates of preterm birth in the E. coli group, clinical and laboratory characteristics only differed marginally.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2015-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Preoperative Diagnostic Challenge of a Long Overlapping Upper Pouch with Distal Tracheoesophageal Fistula","authors":"Takafumi Kondō, Shohei Honda, Masashi Minato, Sorahiko Fujisawa, H. Miyagi, Kazutoshi Cho, H. Minakami, A. Taketomi","doi":"10.4172/2167-0897.1000200","DOIUrl":"https://doi.org/10.4172/2167-0897.1000200","url":null,"abstract":"A wide spectrum of variations can occur in esophageal atresia because of the complexity of tracheoesophageal development. We herein described a 0-day-old boy with type IIIb6 esophageal atresia. Esophagography revealed a long overlapping upper pouch that was similar to esophageal stenosis. Gastrostomy is useful for the therapeutic diagnosis of such a case.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endocrine and Immunological Alterations under Early Nasal Obstruction in Rats Wistar","authors":"Asma Dorbani, Abdelmadjid Bairi, M. Ouakid, A. Tahraoui","doi":"10.4172/2167-0897.1000199","DOIUrl":"https://doi.org/10.4172/2167-0897.1000199","url":null,"abstract":"For most animals smell is the primal sense. One they rely on to identify food, predators and mates. Indeed, for many organisms, odours arc their most efficient means of communicating with others and interpreting their surroundings. Innate behaviour in response to smell is essential to these organisms' survival and most likely result s from nonconscious perception of odours. This article is part of a research program dealing with the consequences of bilateral nasal obstruction (NO) during the postnatal development of mammals. Its aim was to test if the absence of nasal respiration and the related transition to chronic oral breathing could perturb the development of the individual. Therefore, a NO was induced in 8-day old rats (D8) and its effects were investigated 24 h after the treatment (D9), at the end of the obstruction period (D15) and six days after the reopening of the nostrils (D21). The results showed that NO affect some hormonal functions, these modifications were pronounced at D9, D15 and D21. Lastly, NO was associated with an atrophy of the brain at D15, it was maintained until D21. In rats, nasal obstruction can thus be considered like a multifactorial stressful situation. Its effects lasted until adulthood.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"04 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70812236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of Therapeutic Hypothermia Therapy on Six Cases with Persistent: Pulmonary Hypertension and Moderate to Severe Hypoxic Ischemic Encephalopathy using Inhaled Nitric Oxide Therapy","authors":"Keisuke Kobata, M. Nabetani, Nanae Yutaka, Hiroyuki, Sanno","doi":"10.4172/2167-0897.1000198","DOIUrl":"https://doi.org/10.4172/2167-0897.1000198","url":null,"abstract":"We experienced six cases who could undergo therapeutic hypothermia (TH) therapy combined with inhaled nitric oxide (iNO) therapy and one persistent pulmonary hypertension (PPHN) case who could undergo and stop TH during 2002-2014. We experienced no complication in these six cases. We have compared perinatal factors, MRI findings around one-year-old, Gross Motor Function Classification System (GMFCS) and developmental quotient around one and a half year old between 6 cases who underwent TH therapy completely combined with iNO therapy (TH+iNO group) and 38 cases who underwent only TH therapy (TH group). There are no significant differences of perinatal factors, MRI findings, GMFCS, and developmental quotient between (TH+iNO group) and (TH group). These results showed TH could be performed safely for HIE cases with PPHN combined with iNO therapy maintaining the stable condition of respiration and circulation. We need to investigate more PPHN cases with iNO therapy to clarify criteria which cases could be performed TH therapy safely.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70812169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hair Collar Sign and Viral Infection in Pregnancy: Two Clinical Cases","authors":"Tripaldi Clelia, Baldoni Irene, P. Lucio","doi":"10.4172/2167-0897.1000197","DOIUrl":"https://doi.org/10.4172/2167-0897.1000197","url":null,"abstract":"Hair collar sign is a rare malformation of the scalp, often associated with impairment of the central nervous system such as encephaloceles, meningoceles, and heterotopic brain tissue. We describe the cases of two male neonates, with maternal history positive for viral infections in pregnancy and no associated malformations of the nervous system, but coexistence of cutaneous plan nevi.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"14 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70812257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Remission in Congenital Leukemia AML-M1 with Pericardial Effusion","authors":"A. Bülbül, M. Dursun, Yıldız Yıldırmak, B. Akyol, Umut ZübarioÄlu, E. Ünal, Lida Bülbül, Selcen YaroÄlu KazancÄ, S. Uslu","doi":"10.4172/2167-0897.1000196","DOIUrl":"https://doi.org/10.4172/2167-0897.1000196","url":null,"abstract":"Congenital leukemia is a very rare malignancy of childhood with a poor prognosis. The incidence is nearly 1 in 5 million live births. The majority of cases are acute myeloblastic leukemia with trisomy. Clinical manifestations are usually leukocytosis, petechia, ecchymosis, cutaneous nodules, hepatosplenomegaly and central nervous system symptoms. 23-days old girl was presented with complaints of maculopapular dermatitis and hepatosplenomegaly diagnosed as AML M1. During the follow-up period massive pericardial effusion was detected. This case is presented due to emphasize the rare association of pericardial effusion with congenital leukemia without trisomy and spontaneous remission of leukemia that was occasionally appear in the literature.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000196","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Markers of Neonatal Outcomes in Full Term Neonates Suffering from Perinatal Asphyxia","authors":"N. Vargas, M. E. Ceccon, Mario CiceroFalcao, W. B. Carvalho","doi":"10.4172/2167-0897.1000193","DOIUrl":"https://doi.org/10.4172/2167-0897.1000193","url":null,"abstract":"Abstract \u0000Objective The aim of this study were, using only the score clinic of Sarnat and Sarnat, the blood markers of asphyxia that are routinely used in all hospitals of our country (Brazil) and the ultrasonography imaging method performed with 24 and 72 hours and 28 days of life, verify if these are sufficient to detect the neurological evolution of the patient. \u0000Methods \u0000The study was conducted with a prospective cohort of term newborns that suffering perinatal asphyxia by Buonocore criteria (2002). These criteria identify the level of the pH in cord blood that was collected of all newborns and also the blood markers: glutamic oxaloacetic transaminase, glutamic pyruvate transaminase, lactate dehydrogenase and creatine kinase (CKMB).These testes were collected at birth, with 24, 48 and 72 hours of life. The score clinical of Sarnat and Sarnat was performed with 24 hours, 48 hours and 72 hours of life and the ultrasound skull with 24, 48, 72 hours of life and in the end of neonatal period with 28 days of life. The period of study was one year. \u0000Results \u0000In the study´s period 2989 babies were born. The Buonocore criteria were found in 28 newborn showing a frequency of 1% of perinatal asphyxia. The marker of asphyxia were between the normal value of reference and only de iso-enzyme CKMB was a good marker, com value more than 5,10 ng/mL. The brain ultrasonography was altered with 72 hours of life, but one newborn presented alterations only with 28 days of life. The clinical examination using the clinical score of Sarnat and Sarnat demonstrated that 21,42% presented hypoxic-ischemic encephalopathy. In the ROC curve we observed sensitivity of 85,7%, specificity of 85,7% and accuracy of 85,7% correlated the value of CKMB and the brain ultrasonography of 72 hours of life. Conclusions \u0000Perinatal asphyxia may be diagnosed in any hospital if the neonatologist or the neurologist apply the easy score clinical of Sarnat and Sarnat, the iso-enzime CKMB and the serial ultrasonography. In this study the worse alteration was with 72 hours of life, however we must be careful because in one neonate the alteration was present only with 28 days of life.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2015-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Case of Congenital Syngnathia","authors":"M. S. Raban, S. J. Muller, M. Harrison","doi":"10.4172/2167-0897.1000192","DOIUrl":"https://doi.org/10.4172/2167-0897.1000192","url":null,"abstract":"Congenital syngnathia is a rare anomaly characterised by the presence of soft tissue (synechia) or bony adhesions (synostosis) between the maxilla and mandible. A wide spectrum and range of severity have been documented in case reports. Primarily it manifests in the inability to open the mouth; impacting on mandibular growth, nutrition, speech and management of the airway. The bony adhesions can be classified as partial or complete, as well as syndromic and non-syndromic. The aetiology of congenital syngnathia remains unknown. We describe a growth restricted, premature infant diagnosed postnatal with multiple congenital anomalies including syngnathia, craniosynostosis, ventriculomegaly, microcephaly, bilateral cataracts, facial dysmorphism, small kidneys, hypoplastic prepuce of the genitalia and bilateral syndactyly of toes 2, 3 and 4. The rare finding of syngnathia with the associated findings in a premature male infant weighing 1065 g at 31 weeks of corrected gestational age is the first to be reported.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}