Journal of metabolic and bariatric surgery最新文献

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An evaluation of micronutrient status in severe obesity and follow-up assessment after bariatric surgery: A retrospective single-center study 重度肥胖患者微量营养素状况评估及减肥手术后随访评估:一项回顾性单中心研究
Journal of metabolic and bariatric surgery Pub Date : 2022-09-01 DOI: 10.4103/jbs.jbs_11_22
Saba Khan, Astha Sachan, P. Arumugaswamy, Archna Singh, S. Aggarwal, Rakhee Yadav
{"title":"An evaluation of micronutrient status in severe obesity and follow-up assessment after bariatric surgery: A retrospective single-center study","authors":"Saba Khan, Astha Sachan, P. Arumugaswamy, Archna Singh, S. Aggarwal, Rakhee Yadav","doi":"10.4103/jbs.jbs_11_22","DOIUrl":"https://doi.org/10.4103/jbs.jbs_11_22","url":null,"abstract":"Background: Micronutrient deficiency is common in obesity despite surplus weight and high caloric intake. Further exacerbation is often seen after bariatric surgery due to the resultant dietary restrictions, and physiological and anatomical alterations. Owing to the rising prevalence of obesity in India with a simultaneous surge in bariatric surgeries, an account of micronutrient status is required. This will help in identifying susceptible individuals and setting up priorities for prevention and intervention. Subjects and Methods: A retrospective study was designed to analyze the data collected before and until 1 year (3, 6, and 12 months) after bariatric surgery in individuals with severe obesity (body mass index ≥35 kg/m2, n = 150). We included the assessment of nutritional parameters, namely, serum iron, ferritin, total iron-binding capacity, Vitamin B12, folic acid, homocysteine, calcium, phosphorus, Vitamin D, and parathormone along with anthropometric and routine biochemical investigations. Results: Deficiency of Vitamin D was most prevalent (52%) at baseline, followed by anemia (21%). Ferritin deficiency was 9.3%, followed by iron (8.0%), Vitamin B12(7.3%), and folate deficiency (4.7%) at baseline. There was a remarkable improvement in Vitamin D deficiency (26%), whereas the percent prevalence of other micronutrients has shown deterioration in 12 months after bariatric surgery. No significant difference existed in the prevalence of micronutrient deficiency between laparoscopic sleeve gastrectomy (n = 75) and laparoscopic Roux-en-Y gastric bypass surgery (n = 75) over the 12-month follow-up period. Conclusion: Micronutrient deficiencies persisted after bariatric surgery underlining the need for fine adjustment of supplementations and monitoring compliance to ensure the best patient outcomes.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84853649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
microRNA profiling and the effect on metabolic biomarkers and weight loss after laparoscopic sleeve gastrectomy: A prospective cohort study microRNA分析及其对腹腔镜袖式胃切除术后代谢生物标志物和体重减轻的影响:一项前瞻性队列研究
Journal of metabolic and bariatric surgery Pub Date : 2022-09-01 DOI: 10.4103/jbs.jbs_8_22
M. Hany, Hala M Demerdash, Asmaa. H. Ahmed, A. Agayby, Mohamed Ghaballa, Mohamed Ibrahim, P. Maged, B. Torensma
{"title":"microRNA profiling and the effect on metabolic biomarkers and weight loss after laparoscopic sleeve gastrectomy: A prospective cohort study","authors":"M. Hany, Hala M Demerdash, Asmaa. H. Ahmed, A. Agayby, Mohamed Ghaballa, Mohamed Ibrahim, P. Maged, B. Torensma","doi":"10.4103/jbs.jbs_8_22","DOIUrl":"https://doi.org/10.4103/jbs.jbs_8_22","url":null,"abstract":"Background: Epigenetic changes after bariatric surgery are of increasing interest; we evaluated the levels of two circulating microRNAs (miRNA-222 and miRNA-146a) before and after the laparoscopic sleeve gastrectomy (LSG) and the effect of weight loss on the levels of metabolic biomarkers. Materials and Methods: We prospectively evaluated patients pre- and 12 months post-LSG for percent excess weight loss (%EWL), miRNAs levels, metabolic biomarkers (leptin, ghrelin, peptide YY, and glucagon peptide-1 [GLP-1]) levels from August 2019 to September 2021. Results: Significant differences were observed in the miRNA146a-3p (median: 0.64 (0.012-2.68) vs. 1.07 (0.1-3.6); P = 0.019) and miRNA222-5p (median 1.80 (0.1–3.61) vs. 1.19 (0.1-3.68); P = 0.003) levels before and after (12 months) LSG; fasting leptin, ghrelin, insulin, total cholesterol, high- and low-density lipoproteins, fasting blood sugar (FBS), and triglyceride levels also showed significant differences. Significant changes were observed in postprandial values of glucagon-like peptide l (GLP-1) (P = 0.0001) and peptide YY (P = 0.0006) 12 months after LSG. Homeostatic model assessment of insulin resistance (IR) was significantly correlated with %EWL, miRNA146a, and miRNA222-5p (P = 0.002). Postoperatively measured miR146a-39 and miRNA222-5p showed significant coefficient of determination R2 of 0.184 (P = 0.008) and 0.259, P = 0.0007 toward %EWL, respectively. Furthermore, significant correlations of miRNA146a were observed with FBS and IR. Conclusions: LSG-mediated weight loss affected the plasma levels of miR146a and miR222-5p. Due to the simultaneous decrease of ghrelin and increase of postprandial hormones (peptide YY and GLP-1), medical problems in patients with obesity were reduced. This study identified miRNAs as the new markers in the treatment, diagnosis, and therapeutic direction of patients with obesity.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74979681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and Management of Postoperative Complications After Sleeve Gastrectomy. 袖式胃切除术术后并发症的诊断与处理。
Journal of metabolic and bariatric surgery Pub Date : 2022-06-01 DOI: 10.17476/jmbs.2022.11.1.1
Ji Yeon Park
{"title":"Diagnosis and Management of Postoperative Complications After Sleeve Gastrectomy.","authors":"Ji Yeon Park","doi":"10.17476/jmbs.2022.11.1.1","DOIUrl":"https://doi.org/10.17476/jmbs.2022.11.1.1","url":null,"abstract":"<p><p>Sleeve gastrectomy (SG) has demonstrated excellent outcomes in terms of weight loss and resolution of obesity-related comorbidities as a single procedure. It has gained rapidly increasing popularity among bariatric surgeons and patients over the last two decades. This is due to its relative ease of use and less frequent morbidities related to the procedure. Even though the overall complication rate after SG is reported to be lower than conventional Roux-en-Y gastric bypass or biliopancreatic diversion, it still affects 1-10% of the patients undergoing SG, which is not negligible. Early postoperative complications that can occur within 30 days after SG include hemorrhage, leakage, sleeve stenosis, and reflux. Thromboembolic events are rare but can occur after surgery. Here, we review the incidence, diagnosis, and management of these early postoperative complications.</p>","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/85/3b/jmbs-11-1.PMC9848960.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9132378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Outcomes of 75 consecutive cases of laparoscopic one-anastomosis gastric bypass: A prospective study 连续75例腹腔镜单吻合术胃旁路术的前瞻性研究
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_13_21
Dhananjay Pandey, L. Yadav, Kona Lakshmi, R. Trivikraman
{"title":"Outcomes of 75 consecutive cases of laparoscopic one-anastomosis gastric bypass: A prospective study","authors":"Dhananjay Pandey, L. Yadav, Kona Lakshmi, R. Trivikraman","doi":"10.4103/jbs.jbs_13_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_13_21","url":null,"abstract":"Background: Obesity is increasing at an alarming rate in India along with rest of the world. In the National Family and Health survey - IV conducted in 2015-16; 31.3% women and 26.6% men in urban area were obese or over weight. Bariatric surgery has long been introduced for weight control and is well established measure and superior to other weight control measures. Procedures like laparoscopic Roux en Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are more commonly performed than Laparoscopic One Anastomosis Gastric Bypass (LOAGB). Although sufficient data has accumulated in literature regarding the safety and efficacy of LOAGB, some of standard textbooks still mention it as an experimental procedure and not the mainstream procedure. Aims and Objective: The present study was conducted with objective to find out changes in pre-operative and post-operative status of diabetes mellitus, hypertension, dyslipidemia, obstructive sleep apnoea, osteoarthritis, GERD and quality of life after laparoscopic one anastomosis gastric bypass along with its safety and efficacy in Indian population. Material and Methods: The study was conducted at a tertiary care bariatric surgical centre and included 75 consecutive individual operated between January 2016 to December 2017 who underwent Laparoscopic One Anastomosis Gastric Bypass and followed prospectively for minimum 1 year (mean 18 months) and statistical analysis was done using SPSS 21 software. Result: One Anastomosis Gastric Bypass was completed laparoscopically in all the patients without need for conversion to an open procedure. The overall complication with Laparoscopic One Anastomosis Gastric Bypass was 1.3% without any mortality. Mean percentage of excess weight loss (% EWL) achieved was 72.73. 93.9 % patients with diabetes, 67.43% patients with hypertension, 87.1% patient with hyperlipidemia, all the patient with obstructive sleep apnoea and osteoarthritis of knee showed improvement in their disease status. None of the patient showed worsening of gastroesophageal reflux or development of new symptoms of gastro esophageal reflux. All patients had improvement in their quality of life as seen in the improvement of their SF 36 scores. Conclusion: Laparoscopic One Anastomosis Gastric Bypass is a safe and effective bariatric procedure. The post procedure improvement in diabetes, hypertension, hyperlipidemia, obstructive sleep apnoea, osteoarthritis of knee and quality of life is significant in Indian context.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88134394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revision of Roux-en-Y-Gastric bypass – Our experience in Indian patients roux -en- y胃旁路术的改良-我们在印度患者中的经验
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_11_21
N. Verma, R. Wadhawan, L. Sehgal, D. Veetil, Muneendra Gupta
{"title":"Revision of Roux-en-Y-Gastric bypass – Our experience in Indian patients","authors":"N. Verma, R. Wadhawan, L. Sehgal, D. Veetil, Muneendra Gupta","doi":"10.4103/jbs.jbs_11_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_11_21","url":null,"abstract":"Background: The indications for revision bariatric surgery include inadequate weight loss, weight regain, failure to resolve comorbidities, and complications associated with primary surgery. Objectives: The objective is to evaluate the outcome of revision of Roux-en-Y gastric bypass (RYGB) and compare the efficacy of different revision procedures for weight regain, resolution of comorbidities, and complications, if any. Methods: Revision cases performed between May 2017 and April 2021 were included. The analysis of collected data was carried out for weight loss, resolution of comorbidities, and adverse outcomes. Results: Twenty three revision procedures were performed. Two patients were lost to follow-up. The overall complication and reoperation rates were 14.29% and 4.76%, respectively. The follow-up duration was at 6, 12, and 36 months. Twenty-one (91.3%) patients completed 6-month, 18 (78.3%) 12-month, and nine (39.1%) completed 36-month follow-up. The mean postoperative body-mass index at 6, 12, 36 months were 33.07+/−4.15, 33.11+/−4.05, 34.5 ± 8.81, respectively. The mean %excess weight loss (EWL) at 6, 12, 36 months were 39.47+/−13.76, 43.70+/−13.70, 41.14+/−8.48%, respectively. The patients were divided into three groups. Group A - lengthening of biliopancreatic limb (BPL) by 100 cm (n = 6); Group B - placement of ring with a diameter of 7.5 cm in addition to BPL lengthening (n = 12); and Group C - pouch trimming with BPL lengthening by 100 cm (n = 3). %EWL at 6 months was 31.86, 47.69, and 53.49, in Groups A, B, and C, respectively. Similar trends in %EWL were observed in three groups at 12 and 36 months. Conclusion: Revision bariatric surgeries are complex procedures. In our study, banded RYGB with BPL lengthening had better outcomes, though a statistical significance could not be established due to the small sample size and retrospective nature of the study.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75321314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leaks after sleeve gastrectomy – A narrative review 袖式胃切除术后的渗漏-一个叙述性的回顾
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_2_21
N. Jain, R. Bhojwani, K. Mahawar
{"title":"Leaks after sleeve gastrectomy – A narrative review","authors":"N. Jain, R. Bhojwani, K. Mahawar","doi":"10.4103/jbs.jbs_2_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_2_21","url":null,"abstract":"Background: Laparoscopic sleeve gastrectomy has become a standalone procedure for the treatment of severe obesity with excellent short- and mid-term outcome. Staple-line leak is one of the most dreaded complications of this procedure. Following a standardized sequence of critical steps can help decrease the incidence of leaks. In this review, we examine the etiopathogenesis of leaks after laparoscopic sleeve gastrectomy and important implicated technical considerations. Materials and Methods: A comprehensive literature search of various databases was performed with relevant keywords. The published scientific literature was critically appraised. Results: Patient-, surgery-, and surgeon-related risk factors should be recognized and modifiable risk factors should be addressed. There are anatomical, physiological, and technical considerations that contribute to the pathogenesis of leaks, based on which a multitude of precautions need to be taken to prevent staple-line leak. Conclusion: The correct bougie size, distance from the pylorus, stapler size, orientation of staple line, and distance from angle of His and an intraoperative leak test are some of the crucial aspects for a successful outcome after sleeve gastrectomy. Staple size less than that of 1.5 mm should not be used on the stomach, stapling should be initiated at least 5 cm from pylorus and calibrated on a bougie that should not be <32 Fr size. Reinforcing the staple line reduces the incidence of hemorrhage, and current evidence indicates the incidence of leak. Performing a leak test, though offers less sensitivity to predict a leak, does help in detecting the immediate mechanical failure of staple line.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83159094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Management of gastrojejunostomy anastomotic leak post one anastomosis gastric bypass with a covered stent alone 胃空肠吻合术吻合口漏的处理
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_6_21
P. Bhatia, H. Sheth, S. Bhatia, S. Baig
{"title":"Management of gastrojejunostomy anastomotic leak post one anastomosis gastric bypass with a covered stent alone","authors":"P. Bhatia, H. Sheth, S. Bhatia, S. Baig","doi":"10.4103/jbs.jbs_6_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_6_21","url":null,"abstract":"Leaks after one anastomosis gastric bypass are managed based on the timing of presentation and the presence or absence of peritonitis. Reoperation is strongly advocated because of the potential severity of biliary peritonitis. Recently, nonoperative treatment is being increasingly employed, especially for staple line disruptions or unspecified leaks. We report successful usage of a covered esophageal stent in a gastrojejunostomy anastomosis leak with a favorable outcome.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84194804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thirty-day morbidity and mortality of bariatric and metabolic surgery in patients with type 2 diabetes mellitus: A subset analysis of the GENEVA cohort study 2型糖尿病患者减肥和代谢手术的30天发病率和死亡率:日内瓦队列研究的一个亚组分析
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_1_21
R. Singhal, V. Cardoso, C. Ludwig, J. Super, Yashasvi Rajeev, G. Rudge, G. Gkoutos, K. Mahawar, GENEVA collaborators, Ashraf M Shoma
{"title":"Thirty-day morbidity and mortality of bariatric and metabolic surgery in patients with type 2 diabetes mellitus: A subset analysis of the GENEVA cohort study","authors":"R. Singhal, V. Cardoso, C. Ludwig, J. Super, Yashasvi Rajeev, G. Rudge, G. Gkoutos, K. Mahawar, GENEVA collaborators, Ashraf M Shoma","doi":"10.4103/jbs.jbs_1_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_1_21","url":null,"abstract":"Introduction: There is a paucity of data in the scientific literature on the morbidity and mortality of bariatric and metabolic surgery (BMS) in individuals suffering from Type 2 diabetes mellitus (T2D). The current study is a secondary analysis of the GENEVA dataset to understand this. Materials and Methods: Logistic regressions were performed to investigate the influence of diabetes on complication rates and procedure selection. Ethical approval was not required. Results: One thousand four hundred and seventy-five of these patients were suffering from T2D at the time of the surgery (416 diet-treated type 2 diabetes), 806 oral agent-treated type 2 diabetes, and 253 insulin-treated type 2 diabetes [ITD]). Six hundred and fifty (44.1%) of these patients underwent laparoscopic sleeve gastrectomy (LSG); 487 (33%) underwent Roux-en-Y gastric bypass; 230 (15.6%) underwent a one anastomosis gastric bypass (OAGB); and 108 (7.3%) underwent some other procedures. The 30-day mortality of BMS in those without T2D was 0.07% (4/5609) as compared to 0.4% (6/1475) and 0.8% (2/253) in those with T2D and ITD, respectively. 7.9% of those with T2D developed a 30-day complication compared to 6.5% without T2D (P = 0.0475). There was an increased risk of complications in patients with ITD on univariate and multivariate analysis. Patients with T2D were significantly less likely to undergo an LSG and significantly more likely to undergo an OAGB. Conclusions: ITD patients undergoing BMS experienced significantly higher 30-day morbidity and mortality. Although LSG was the most common procedure in patients with T2D, these patients were less likely to undergo LSG than patients without T2D.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73224757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medium-Term outcomes after Roux-en-Y-Gastric Bypass: Experience from a Tertiary Healthcare Center from India roux -en- y胃旁路手术的中期结果:来自印度三级医疗中心的经验
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_2_22
P. Arumugaswamy, Vitish Singla, S. Aggarwal
{"title":"Medium-Term outcomes after Roux-en-Y-Gastric Bypass: Experience from a Tertiary Healthcare Center from India","authors":"P. Arumugaswamy, Vitish Singla, S. Aggarwal","doi":"10.4103/jbs.jbs_2_22","DOIUrl":"https://doi.org/10.4103/jbs.jbs_2_22","url":null,"abstract":"Background: Roux en Y gastric bypass (RYGB) has been highly effective in weight loss and it has been the procedure of choice for patients suffering from diabetes. There is a high attrition rate in long-term follow-up. Hence, limited long-term data are available. Methodology: We collected retrospectively data from a prospectively maintained institutional database. To increase the long-term follow-up rate, a telephonic interview was conducted with patients who had not come for long-term follow-up. Standard definitions were used for weight loss, weight regain, comorbidities, comorbidity resolution, and nutritional parameters. Results: Of 142 patients who underwent laparoscopic RYGB between 2008 and 2018, 125 patients (M: 33, F: 92; Age: 42.4 ± 5.2 years) were included in the study. The mean % weight loss at 1, 3, 5, and 7 years was 28.9, 31.8, 31.3, and 31.7, respectively. Mean % excess body mass index loss (% EBMIL) at 1, 3, 5, and 7 years was 67.6 ± 18, 73.7 ± 17.9, 71.7 ± 20.7, and 69.5 ± 24.6, respectively. Median weight regain at 3, 5, and 7 years was 8.4%, 12.7%, and 24% of weight lost. Significant weight regain was seen in 1 patient at 3 years and 3 patients at 5 and 7 years of follow-up. Among patients suffering from diabetes, 50.9% had remission and 45.3% had improvement at 1 year. At 5 years, this was 56% and 40%, respectively. Among patients suffering from hypertension, at 5 years, remission was seen in 11 (64.7%) out of 17. Significant improvements were seen in hypothyroidism, OSA, gastroesophageal reflux disease, and lipid profile. There was a statistically significant decrease in mean levels of fasting blood sugar, glycated hemoglobin (HbA1c), hemoglobin, serum calcium, insulin, c-peptide, serum albumin, and total protein and there was an increase in mean Vitamin D levels at 1 year follow-up. There was a decrease in mean levels of folate, total iron-binding capacity, parathyroid hormone, and alkaline phosphatase and an increase in mean Vitamin B12, iron, and ferritin postsurgery. However, this was statistically not significant. Nutritional deficiencies were noted. Seven complications were noted out of 142 procedures and no surgery-related mortality. Three patients had significant weight regain beyond 5 years. Conclusion: RYGB is a safe and effective bariatric procedure with well-sustained results in long run. Nutritional supplementation is required to correct deficiencies.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74639503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early weight loss: A determinant of total weight loss after bariatric surgery 早期体重减轻:减肥手术后总体重减轻的决定因素
Journal of metabolic and bariatric surgery Pub Date : 2022-05-01 DOI: 10.4103/jbs.jbs_3_21
Sigin Satheesh, A. Shetty, A. Nasta, Madhu Goel, Ramen Goel
{"title":"Early weight loss: A determinant of total weight loss after bariatric surgery","authors":"Sigin Satheesh, A. Shetty, A. Nasta, Madhu Goel, Ramen Goel","doi":"10.4103/jbs.jbs_3_21","DOIUrl":"https://doi.org/10.4103/jbs.jbs_3_21","url":null,"abstract":"Background: Bariatric surgery is the most effective weight loss intervention for patients with severe obesity. Several studies have shown wide variability in weight loss response between patients. The aim of the study is to identify comparative poor responders based on weight loss in the early postoperative period. Methods: A retrospective analysis of 125 patients who underwent primary bariatric surgery by a single surgeon and completed 1 year of follow-up was performed. Patients were divided into two groups based on % Total Weight loss (%TWL) at 1 month after surgery: Group 1-who lost <10% TWL and Group 2-who lost >10% TWL. The comparison of factors in both groups at different time points was executed using paired t-tests or analysis of variance. The relationships between Group 1 and Group 2 after 1 year follow-up period were assessed through linear regression analyses. Results: Seventy (56%) patients lost <10% TWL and 55 (44%) patients lost more than 10% TWL in 1 month after surgery. Mean weight loss at 1 month and 1 year after surgery was 9 ± 5.5 kg and 37 ± 13.3 kg in Group 1 compared to 16 ± 5.2 and 46 ± 16.4 kg in Group 2, respectively. Patients with >10%TWL at 1 month had significantly greater %TWL at 1 year (P = 0.001). Linear regression analysis showed a positive correlation between patients who lost >10%TWL 1 month after surgery and weight loss at 1 year. Conclusion: Postoperative percentage TWL of <10% at 1 month can be used as an early determinant of comparatively poor weight loss at 1 year. Early initiation of aggressive and multimodal treatment strategies is likely to improve overall weight loss outcomes after surgery.","PeriodicalId":73828,"journal":{"name":"Journal of metabolic and bariatric surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84668918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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