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Journal of biotechnology and its applications最新文献

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Pathophysiologic Functions of Carbohydrate-Lipid Interactions: Ascertainment in Obesity, Diabetes and SARS-CoV-2/COVID-19 碳水化合物-脂质相互作用的病理生理功能：确定肥胖、糖尿病和SARS-CoV-2/neneneba COVID-19
Journal of biotechnology and its applications Pub Date : 2022-06-30 DOI: 10.33425/2771-9014.1005
Chrysanthus Chukwuma
{"title":"Pathophysiologic Functions of Carbohydrate-Lipid Interactions: Ascertainment in Obesity, Diabetes and SARS-CoV-2/COVID-19","authors":"Chrysanthus Chukwuma","doi":"10.33425/2771-9014.1005","DOIUrl":"https://doi.org/10.33425/2771-9014.1005","url":null,"abstract":"The extant COVID-19 pandemic has resulted in an expansive mortality due to the SARS-CoV-2. The SARS-CoV-2 is encompassed by a lipid bilayer that enhances fusion of the viral membrane to the host cell, replication, endocytosis, exocytosis and role of lipid metabolism in viral infectivity. In the absence of appropriate drugs and vaccines, there are never-ending opportunities for antiviral treatments. Consumption of diets suffused with carbohydrates and saturated fats contribute to obesity and diabetes prevalence, oxidative stress and comorbidities development as risk factors for COVID-19 pandemic as an emergency public health enigma. COVID-19 outbreak has invariably constituted a severe challenge to global public health system with resultant deficient approaches to stem the disorder but carbohydrates may provide accelerated diagnostics, appropriate, effective and efficient vaccines and therapeutic regimen. This paper provides a set of themes and modalities for analysing carbohydrate-lipid interactions as extrapolated to the issues and challenges of SARS-CoV-2, the causative agent of the COVID-19 pandemic.","PeriodicalId":73624,"journal":{"name":"Journal of biotechnology and its applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46244933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Perspective on Needs Identification for Successful Cardiovascular Device Innovation 成功心血管器械创新的需求识别视角
Journal of biotechnology and its applications Pub Date : 2022-06-30 DOI: 10.33425/2771-9014.1001
E. Goldenberg, Wesley Pedersen
{"title":"A Perspective on Needs Identification for Successful Cardiovascular Device Innovation","authors":"E. Goldenberg, Wesley Pedersen","doi":"10.33425/2771-9014.1001","DOIUrl":"https://doi.org/10.33425/2771-9014.1001","url":null,"abstract":"A compelling “need” identification is essential prior to initiating the lengthy, demanding and often frustrating pathway necessary for cardiovascular device innovation and development. Over the past few decades both iterative and transformational treatments have been especially profound in cardiovascular interventional and surgical approaches which have necessitated innovation in devices to bring these novel approaches to fruition. Stakeholders in the development of such devices have included amongst others, clinicians, patients and institutions. Given the numerous hurdles for medical device development including the need for multidisciplinary teams, establishing intellectual property portfolios, conducting market in tandem with academic research, funding, identifying regulatory and reimbursement strategies, a rigorous process for needs verification is mandatory. This vital first step needs to be methodical and is the topic of brief discussion in this perspective manuscript.","PeriodicalId":73624,"journal":{"name":"Journal of biotechnology and its applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46819959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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