JMM case reports最新文献

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A case report of brain abscess caused by Nocardia cyriacigeorgica in a diabetic patient. 糖尿病患者脑脓肿1例报告由cyriacigorgica诺卡菌引起。
JMM case reports Pub Date : 2018-01-10 eCollection Date: 2018-09-01 DOI: 10.1099/jmmcr.0.005133
Mehdi Khorshidi, Sepehr Navid, Davood Azadi, Darioush Shokri, Hasan Shojaei
{"title":"A case report of brain abscess caused by <i>Nocardia cyriacigeorgica</i> in a diabetic patient.","authors":"Mehdi Khorshidi,&nbsp;Sepehr Navid,&nbsp;Davood Azadi,&nbsp;Darioush Shokri,&nbsp;Hasan Shojaei","doi":"10.1099/jmmcr.0.005133","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005133","url":null,"abstract":"<p><strong>Introduction: </strong><i>Nocardia</i> are Gram-positive partially acid-fast bacilli capable of inducing a wide range of infections in patients with immunodeficiency, AIDS, cancer, lupus erythematous and diabetes. <i>Nocardia cyriacigeorgica</i> was first isolated in 2001 from a patient with chronic bronchitis. Since then, there have been reports on the clinical significance of this organism in patients with bronchitis, brain abscess and lung diseases. We, herein, report a case of brain abscess in an elderly diabetic patient from Iran.</p><p><strong>Case presentation: </strong>The patient was a 73 year-old woman admitted to hospital due to severe headache and shortness of breath. The patient had lived with diabetes for 20 years and suffered from chronic foot ulcer. She was admitted to hospital with fever, weakness, drowsiness and vomiting. Clinical examination and the head CT scan of the left frontal lobe of the brain revealed a metastatic carcinoma involving skull bone in the tumor that resulted in two surgical operations in the following two years. The brain abscess biopsy revealed an infection with <i>Nocardia cyriacigeorgica</i> confirmed by phenotypic and molecular tests including a PCR-based amplification of a target genetic marker, a 596 bp fragment of 16S rRNA gene, followed by almost full 16S rRNA sequencing.</p><p><strong>Conclusion: </strong>The rare infections, such as brain abscess with <i>Nocardia,</i> are easily neglected or misdiagnosed due to the fastidious nature of the organism and inadequate microbiological experience of laboratories in the hospitals of developing countries. This case shows that hospitals should consider a better laboratory protocol to deal with the clinical cases in which fastidious organisms, and in particular <i>Nocardia</i>, are involved.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 9","pages":"e005133"},"PeriodicalIF":0.0,"publicationDate":"2018-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36722110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
A case of oropharyngeal Ureaplasma urealyticum infection in a human immunodeficiency virus positive bisexual male co-infected with human papilloma virus and Treponema pallidum. 人类免疫缺陷病毒阳性双性恋男性口咽解脲原体感染一例人乳头状瘤病毒和梅毒螺旋体合并感染。
JMM case reports Pub Date : 2018-01-10 eCollection Date: 2018-03-01 DOI: 10.1099/jmmcr.0.005132
Nazneen Arif Suri, Sujeesh Sebastian, Deepika Yadav, Neena Khanna, Benu Dhawan
{"title":"A case of oropharyngeal <i>Ureaplasma urealyticum</i> infection in a human immunodeficiency virus positive bisexual male co-infected with human papilloma virus and <i>Treponema pallidum</i>.","authors":"Nazneen Arif Suri,&nbsp;Sujeesh Sebastian,&nbsp;Deepika Yadav,&nbsp;Neena Khanna,&nbsp;Benu Dhawan","doi":"10.1099/jmmcr.0.005132","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005132","url":null,"abstract":"<p><strong>Introduction: </strong>Management strategies for sexually transmitted infections (STIs) in their extragenital forms address <i>Neisseria gonorrhoeae</i> and <i>Chlamydia trachomatis</i> alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites.</p><p><strong>Case presentation: </strong>A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts. He was reactive for the venereal disease research laboratory (VDRL) test. He tested positive for <i>Ureaplasma</i> spp. both by culture and PCR at urethral and oropharyngeal sites, but was negative at the rectal site. The patient was successfully treated with doxycycline and penicillin, and was followed up with a test of cure at 6 weeks.</p><p><strong>Conclusion: </strong>In view of the disseminating infections that can be caused by <i>Ureaplasma</i> spp., it makes it important to screen for these infections even at non-genital sites, especially in the immunocompromised. STIs may be asymptomatic and can serve as a reservoir of infection in a population. This report should promote all efforts to formulate guidelines for extragenital screening of all STI pathogens.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 3","pages":"e005132"},"PeriodicalIF":0.0,"publicationDate":"2018-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35981195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
First report of Lyme disease in Nepal. 尼泊尔首例莱姆病报告。
JMM case reports Pub Date : 2018-01-10 eCollection Date: 2018-03-01 DOI: 10.1099/jmmcr.0.005128
Sher Bahadur Pun, Sumit Agrawal, Santoshananda Jha, Lila Nath Bhandari, Bimal Sharma Chalise, Abadhesh Mishra, Rajesh Shah
{"title":"First report of Lyme disease in Nepal.","authors":"Sher Bahadur Pun,&nbsp;Sumit Agrawal,&nbsp;Santoshananda Jha,&nbsp;Lila Nath Bhandari,&nbsp;Bimal Sharma Chalise,&nbsp;Abadhesh Mishra,&nbsp;Rajesh Shah","doi":"10.1099/jmmcr.0.005128","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005128","url":null,"abstract":"<p><strong>Introduction: </strong>Lyme disease is a tick-borne illness caused by the spirochete <i>Borrelia burgdorferi</i> and is widely reported in the USA, Central Europe, South East Asia and Latin America. Until recently, no scientific report regarding Lyme disease in Nepal had been published.</p><p><strong>Case presentation: </strong>A 32-year-old, previously healthy female visited the hospital with a history of joint pains, fatigue, neck stiffness, tingling sensation and headache. She was initially treated for typhoid fever, brucellosis and malaria, but did not show significant improvement. Doxycycline was prescribed empirically for 3 weeks for the treatment of suspected tick-borne illness. A two-tiered immunoglobulin laboratory testing confirmed <i>Borrelia burgdorferi</i>. She developed post-treatment Lyme disease syndrome after completion of antibiotic therapy.</p><p><strong>Conclusion: </strong>To the best of our knowledge, this is the first report of Lyme disease in Nepal and probably the first documented case of post-treatment Lyme disease syndrome in Asia. Lyme disease might have been overlooked in Nepal and, therefore, patients having clinical signs and symptoms similar to Lyme disease should not be disregarded in differential diagnosis.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 3","pages":"e005128"},"PeriodicalIF":0.0,"publicationDate":"2018-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35981194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
First confirmed case of nasal pythiosis in a horse in Thailand. 泰国首例马鼻皮癣确诊病例。
JMM case reports Pub Date : 2018-01-09 eCollection Date: 2018-01-01 DOI: 10.1099/jmmcr.0.005136
Walaiporn Tonpitak, Watcharapol Pathomsakulwong, Chulabha Sornklien, Theerapong Krajaejun, Suppathat Wutthiwithayaphong
{"title":"First confirmed case of nasal pythiosis in a horse in Thailand.","authors":"Walaiporn Tonpitak,&nbsp;Watcharapol Pathomsakulwong,&nbsp;Chulabha Sornklien,&nbsp;Theerapong Krajaejun,&nbsp;Suppathat Wutthiwithayaphong","doi":"10.1099/jmmcr.0.005136","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005136","url":null,"abstract":"<p><strong>Introduction: </strong>Pythiosis is caused by <i>Pythium insidiosum</i>, a fungus-like organism in the class <i>Oomycetes</i>. It can infect humans and a variety of animal species in tropical, subtropical and some temperate regions. Cases of animal pythiosis have occurred predominantly in horses in the skin and subcutaneous tissue at the limbs and in the ventral portion of thoracoabdominal wall - lesions in the nasal region are rarely reported. Moreover, although many human pythiosis cases have been reported in Thailand, no cases of animal pythiosis in Thailand have been reported.</p><p><strong>Case presentation: </strong>We report a case of pythiosis in a horse infected at the nasal cavity. Diagnosis was performed by zoospore formation by bait technique, immunohistochemical stain, immunochromatography and sequence analysis.</p><p><strong>Conclusion: </strong>The sequences of rDNA were 99 % and 96 to 99 % identical to GenBank isolates of <i>Pythium insidiosum</i> from two Thai human patients and horses from various countries, respectively. This represents the first confirmed report of nasal equine pythiosis in Thailand.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 1","pages":"e005136"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35938771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Mycobacterium kansasii osteomyelitis - a masquerading disease. 堪萨斯分枝杆菌骨髓炎-一种伪装性疾病。
JMM case reports Pub Date : 2018-01-02 eCollection Date: 2018-01-01 DOI: 10.1099/jmmcr.0.005114
Kiranmai Bhatt, Krishna Banavathi
{"title":"<i>Mycobacterium kansasii</i> osteomyelitis - a masquerading disease.","authors":"Kiranmai Bhatt,&nbsp;Krishna Banavathi","doi":"10.1099/jmmcr.0.005114","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005114","url":null,"abstract":"<p><strong>Introduction: </strong>Non-tuberculous mycobacteria (NTM) are environmental bacteria capable of causing an opportunistic myriad of infections. <i>Mycobacterium kansasii</i>, one such NTM, is responsible for causing pulmonary disease in immunocompromised patients. Rare extrapulmonary manifestations such as lymphadenitis, osteoarticular manifestations, and skin and soft tissue infections are also observed.</p><p><strong>Case presentation: </strong>Here, we report an unusual case of sternoclavicular joint and elbow joint infection with <i>M. kansasii</i> in a relatively immunocompetent patient. Histopathology did not show classic granulomas and mycobacterial infection was not initially considered as a possibility. However repeat biopsies were sent for mycobacterial cultures which then grew <i>M. kansasii</i>.</p><p><strong>Conclusion: </strong>Diagnosis of <i>M. kansasii</i> in such cases can be difficult and culture-positive results may not necessarily imply positive diagnosis as they can be environmental contaminants. Furthermore, <i>M. kansasii</i> can cause infections without the characteristic granuloma formation, which can further complicate tissue diagnosis. This underlines the importance of ensuring that tissue samples obtained are cultured for mycobacteria.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 1","pages":"e005114"},"PeriodicalIF":0.0,"publicationDate":"2018-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35938769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A case of Wohlfahrtiimonas chitiniclastica bacteremia in continental United States. 美国大陆发生几丁质粒胞虫菌血症1例。
JMM case reports Pub Date : 2017-12-21 eCollection Date: 2017-12-01 DOI: 10.1099/jmmcr.0.005134
Jesus A Chavez, Andrew J Alexander, Joan M Balada-Llasat, Preeti Pancholi
{"title":"A case of <i>Wohlfahrtiimonas chitiniclastica</i> bacteremia in continental United States.","authors":"Jesus A Chavez,&nbsp;Andrew J Alexander,&nbsp;Joan M Balada-Llasat,&nbsp;Preeti Pancholi","doi":"10.1099/jmmcr.0.005134","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005134","url":null,"abstract":"<p><strong>Introduction: </strong><i>Wohlfahrtiimonas chitiniclastica</i> has been associated with open wound infections, cellulitis, osteomyelitis, and bacteremia.</p><p><strong>Case presentation: </strong>We report the case of a 41 year old woman with history of congenital myelomeningocele, paraplegia and extensive decubitus ulcers that developed <i>W. chitiniclastica</i> bacteremia secondary to an infected ulcer.</p><p><strong>Conclusion: </strong><i>W. chitiniclastica</i> is an emerging human pathogen that can be readily identified by MALDI-TOF or sequencing.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 12","pages":"e005134"},"PeriodicalIF":0.0,"publicationDate":"2017-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35938768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Shewanella spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review. 西班牙大加那利岛的谢瓦纳菌属感染:31 例病例的回顾性分析和文献综述。
JMM case reports Pub Date : 2017-12-07 eCollection Date: 2017-12-01 DOI: 10.1099/jmmcr.0.005131
Alberto J Martín-Rodríguez, Oriol Martín-Pujol, Fernando Artiles-Campelo, Margarita Bolaños-Rivero, Ute Römling
{"title":"<i>Shewanella</i> spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review.","authors":"Alberto J Martín-Rodríguez, Oriol Martín-Pujol, Fernando Artiles-Campelo, Margarita Bolaños-Rivero, Ute Römling","doi":"10.1099/jmmcr.0.005131","DOIUrl":"10.1099/jmmcr.0.005131","url":null,"abstract":"<p><strong>Introduction: </strong><i>Shewanella</i> spp. can cause severe skin and soft-tissue infections, gastrointestinal infections, otitis and bacteraemia, generally upon contact with seawater or consumption of raw seafood. Recently, a new condition termed 'patera foot' characterized by acute skin and soft-tissue infection has been described in irregular immigrants arriving to the Canary Islands, Spain, in rudimentary boats. Most infections are caused by a single species, <i>Shewanella algae</i>. The improvement of the diagnostic capabilities in clinical microbiology laboratories has resulted in a growing number of cases being reported worldwide, most of them coming from warm regions.</p><p><strong>Case presentation: </strong>In this work, we reviewed the medical records of all the patients with <i>Shewanella</i> infections in the two university hospitals of Gran Canaria (the Canary Islands, Spain) during the period 2000-2016, resulting in the identification of 31 cases. We also conducted a literature review of <i>Shewanella</i> infections reported worldwide in recent years.</p><p><strong>Conclusion: </strong>This case series suggests that <i>Shewanella</i> infections are nosocomially acquired more frequently than previously thought. In addition, the unexpectedly high proportion of multidrug-resistant isolates raises concerns.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 12","pages":"e005131"},"PeriodicalIF":0.0,"publicationDate":"2017-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35980707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertical transmission of Salmonella enterica serotype Paratyphi A leading to abortion. 甲型副伤寒沙门氏菌垂直传播导致流产。
JMM case reports Pub Date : 2017-11-15 eCollection Date: 2017-11-01 DOI: 10.1099/jmmcr.0.005127
Shveta Sethi, Vikas Gautam, Kirti Gupta, Vanita Suri, Archana Angrup
{"title":"Vertical transmission of <i>Salmonella enterica</i> serotype Paratyphi A leading to abortion.","authors":"Shveta Sethi,&nbsp;Vikas Gautam,&nbsp;Kirti Gupta,&nbsp;Vanita Suri,&nbsp;Archana Angrup","doi":"10.1099/jmmcr.0.005127","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005127","url":null,"abstract":"<p><p><b>Introduction.</b> Enteric fever, caused by <i>Salmonella enterica</i> serotype Typhi (typhoid fever) or <i>S. enterica</i> serotype Paratyphi A, B or C (paratyphoid fever), is a major health problem in developing countries. Vertical transmission of <i>Salmonella</i> can cause miscarriage, still birth, preterm labour and neonatal sepsis. In the literature, many cases of vertical transmission of <i>S. enterica</i> Typhi from mother to foetus have been reported, but there are very limited studies showing vertical transmission of <i>S. enterica</i> Paratyphi. <b>Case presentation.</b> Here, we report a rare case of <i>S. enterica</i> serotype Paratyphi A infection in a pregnant woman resulting in a spontaneous miscarriage. <i>S. enterica</i> serotype Paratyphi A was isolated from placental membrane in culture. <b>Conclusion.</b> A high index of suspicion, along with timely cultures of relevant samples, like blood and stool, and timely initiation of antibiotic therapy in pregnancy could possibly save the lives of such foetuses.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 11","pages":"e005127"},"PeriodicalIF":0.0,"publicationDate":"2017-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35669642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Aeromonas wound infection in a healthy boy. 健康男孩气单胞菌伤口感染
JMM case reports Pub Date : 2017-11-14 eCollection Date: 2017-11-01 DOI: 10.1099/jmmcr.0.005129
Bart Rutteman
{"title":"<i>Aeromonas</i> wound infection in a healthy boy.","authors":"Bart Rutteman","doi":"10.1099/jmmcr.0.005129","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005129","url":null,"abstract":"The day afterwards (day 1), the boy returned to the emergency ward with a fever (38.5 C). Physical examination showed no signs of sepsis, a normal ear-nose-throat inspection, and the stitched wound had a normal aspect. Laboratory investigations showed a slight leucocytosis (12.600 cells μl ) with neutrophilia (85%), but a normal C-reactive protein level (6.6mg l ) and sedimentation rate (2mm h ). He was hospitalized andamoxicillin/clavulanic acid was continued (dosed 1000/10 mg kg 1 in 4 doses).","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 11","pages":"e005129"},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35669643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Helicobacter canis bacteraemia and cellulitis in a patient with end-stage renal disease. 终末期肾病患者的犬幽门螺杆菌菌血症和蜂窝织炎
JMM case reports Pub Date : 2017-11-08 eCollection Date: 2017-11-01 DOI: 10.1099/jmmcr.0.005126
Salika M Shakir, Margaret V Powers-Fletcher, E Susan Slechta, Mark A Fisher
{"title":"<i>Helicobacter canis</i> bacteraemia and cellulitis in a patient with end-stage renal disease.","authors":"Salika M Shakir,&nbsp;Margaret V Powers-Fletcher,&nbsp;E Susan Slechta,&nbsp;Mark A Fisher","doi":"10.1099/jmmcr.0.005126","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005126","url":null,"abstract":"<p><p><b>Introduction.</b> Invasive infections by <i>Helicobacter canis</i> are uncommon and occur primarily in immunocompromised patients. Here, we describe a case of <i>H. canis</i> bacteraemia and cellulitis in a patient with end-stage renal disease (ESRD). <b>Case presentation.</b> A 49-year-old male with ESRD on haemodialysis presented to an emergency department with cellulitis overlying his left upper extremity arteriovenous fistula for 3 days without constitutional symptoms. Mild leucocytosis and thrombocytopenia was noted on initial laboratory work up. The patient received a dose of vancomycin initially, and then transitioned to oral doxycycline prior to discharge 3 days later. Blood cultures drawn on admission were positive with curved Gram-negative rods at day 5. Routine sub-cultures initially failed to isolate the organism; however, small, tan colonies were observed on sheep blood agar incubated under microaerobic conditions. <i>H. canis</i> was identified by 16S rRNA sequencing. Antimicrobial-susceptibility testing was not performed due to poor growth and lack of interpretive guidelines. The patient was ultimately treated successfully with amoxicillin/clavulanic acid. <b>Conclusion.</b> This case illustrates the importance of recognizing <i>H. canis</i> infections in immunocompromised patients, especially in those with recent pet exposure. In addition, this case highlights the need for improved laboratory diagnostics for <i>H. canis</i> as isolation and identification of this fastidious organism is challenging.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 11","pages":"e005126"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35669641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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