Italian journal of neurological sciences最新文献_第3页

Stenting of the extracranial internal carotid artery for dissecting aneurysm. 颅外颈内动脉支架置入术治疗夹层动脉瘤。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050040

L Castellan, A Casasco, V Toso, L Bernardi

引用次数: 9

Usefulness of proton magnetic resonance spectroscopy in differentiating parkinsonian syndromes. 质子磁共振波谱在帕金森综合征鉴别中的应用。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050035

F Federico, I L Simone, V Lucivero, D M Mezzapesa, M de Mari, P Lamberti, M Petruzzellis, E Ferrari

{"title":"Usefulness of proton magnetic resonance spectroscopy in differentiating parkinsonian syndromes.","authors":"F Federico, I L Simone, V Lucivero, D M Mezzapesa, M de Mari, P Lamberti, M Petruzzellis, E Ferrari","doi":"10.1007/s100720050035","DOIUrl":"https://doi.org/10.1007/s100720050035","url":null,"abstract":"Proton magnetic resonance spectroscopy ((1)H-MRS) was performed in patients with a clinical diagnosis of idiopathic Parkinson's disease (IPD), multiple system atrophy (MSA) or progressive supranuclear palsy (PSP) in order to assess metabolic differences between the three groups of patients. Single-volume (1)H-MRS, localized to the lentiform nucleus, was carried out in 19 IPD patients, 14 MSA patients, 11 PSP patients and 12 age-matched healthy subjects. The signals of N-acetylaspartate (NAA), choline-containing compounds (Cho) and creatine-phosphocreatine (Cr) were evaluated as peak area ratios. The NAA/Cho peak ratio was significantly reduced in MSA and in PSP patients compared to IPD patients and to controls. The NAA/Cr peak ratio was significantly reduced in MSA, in PSP and in IPD patients compared to controls, but only in MSA compared to IPD patients. The NAA reduction in the basal ganglia of MSA and PSP patients may reflect a neuronal loss or damage. Single-volume (1)H-MRS may be a useful tool in differentiating MSA and PSP from IPD patients.","PeriodicalId":73522,"journal":{"name":"Italian journal of neurological sciences","volume":"20 4","pages":"223-9"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s100720050035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21412250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

Superficial siderosis of the central nervous system and anticoagulant therapy: a case report. 中枢神经系统浅表性铁沉着及抗凝治疗1例。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050039

M Manfredi, E Magni, M Gandolfini, A Beltramello, A Orlandini, E Donati

引用次数: 10

Cytomegalovirus encephalitis: diagnosis with clinical approach, EEG and PCR techniques. 巨细胞病毒性脑炎的临床诊断、脑电图和PCR技术。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050041

M Maschio, F Giudiceandrea, P Contadini, B Jandolo

引用次数: 6

A new case of representational neglect. 代表性忽视的新案例。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050038

A Peru, P Zapparoli

引用次数: 11

Cryptogenic temporal lobe epilepsy. semi-quantitative interictal 99mTc HMPAO SPECT: statistical correlation with clinical data and EEG. 隐源性颞叶癫痫。半定量间期99mTc HMPAO SPECT:与临床资料及脑电图有统计学相关性。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050037

F Paladin, A Bonazza, R Mameli, F Mainardi

{"title":"Cryptogenic temporal lobe epilepsy. semi-quantitative interictal 99mTc HMPAO SPECT: statistical correlation with clinical data and EEG.","authors":"F Paladin, A Bonazza, R Mameli, F Mainardi","doi":"10.1007/s100720050037","DOIUrl":"https://doi.org/10.1007/s100720050037","url":null,"abstract":"The aim of our work was to identify clinical and electroencephalographic factors that are statistically correlated to 99mTc HMPAO hypofixation in cryptogenic temporal lobe epilepsy. We selected a homogeneous group of patients (28 males and 17 females) affected by temporal lobe epilepsy and having normal results on computed tomography and magnetic resonance imaging. Patients were classified according to semeiological characteristics of the seizures, presence or absence of spikes on electroencephalography (EEG), age at onset, illness duration, and drug resistance. The presence of focal interictal spikes on EEG was statistically correlated to 99mTc HMPAO temporal hypofixation (p = 0.04). The other electroclinical factors considered in this series did not play an important role in modifying radiopharmaceutical fixation in focal epilepsy in interictal phase. We speculate that a possible explanation for focal radiopharmaceutical hypofixation, in addition to hypoperfusion, is an increased permeability of the blood-brain barrier (due to perivascular inflammation or other causes) which can be responsible for 99mTc HMPAO escape with a resultant hypofixation.","PeriodicalId":73522,"journal":{"name":"Italian journal of neurological sciences","volume":"20 4","pages":"237-42"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s100720050037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21412705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Guidelines for the diagnosis of Charcot-Marie-Tooth disease and related neuropathies. Ad hoc Working Group of the Peripheral Nervous System Study Group, Italian Neurological Society. 腓骨肌萎缩症及相关神经病的诊断指南。意大利神经学会外周神经系统研究组特设工作组。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050033

D Pareyson

引用次数: 13

Identification of SCA2 mutation in cases of spinocerebellar ataxia with no family history in mid-eastern Sicily. 西西里岛中东部无家族史脊髓小脑性共济失调患者SCA2突变的鉴定

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050034

S Giuffrida, R Saponara, A Trovato Salinaro, D A Restivo, E Domina, M Papotto, F Le Pira, A Nicoletti, A Trovato, D F Condorelli

{"title":"Identification of SCA2 mutation in cases of spinocerebellar ataxia with no family history in mid-eastern Sicily.","authors":"S Giuffrida, R Saponara, A Trovato Salinaro, D A Restivo, E Domina, M Papotto, F Le Pira, A Nicoletti, A Trovato, D F Condorelli","doi":"10.1007/s100720050034","DOIUrl":"https://doi.org/10.1007/s100720050034","url":null,"abstract":"Differential diagnosis between autosomal dominant cerebellar ataxia type I (ADCA I) and idiopathic cerebellar ataxia type P (IDCA-P) is very difficult given only clinical and neuroradiological data. The only certain distinctive characteristic is the presence or absence of family history. We observed 7 patients with late-onset cerebellar ataxia associated with other non-cerebellar signs and without a family history of the disease in which clinical signs were comparable to symptoms found in SCA2. The neuroradiological study showed olivopontocerebellar atrophy in all patients and the presence of hyperintensity of the transverse pontine fibers in 6 patients (85. 6%); molecular analysis showed SCA2 mutations in 2 patients. We also report the case of a patient who was initially considered as IDCA-P but who was later correctly identified as SCA2 with an atypical family history (false IDCA-P), after a genetic mutation was found and following an interview with the mother. Our data suggest that spinocerebellar ataxia syndrome should be defined as idiopathic not only after having excluded the possible symptomatic causes but also in the absence of family history, after having excluded the presence of genetic mutation. We believe that family history, in late-onset spinocerebellar ataxia, cannot be considered as the differential criterion among hereditary (ADCA-I) and non-hereditary (IDCA-P) forms; molecular analysis is required for a correct diagnosis.","PeriodicalId":73522,"journal":{"name":"Italian journal of neurological sciences","volume":"20 4","pages":"217-21"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s100720050034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21412249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Low-oestrogen oral contraceptives as a major risk factor for cerebral venous and sinus thrombosis: evidence from a clinical series. 低雌激素口服避孕药是脑静脉和窦血栓形成的主要危险因素:来自临床系列的证据。

Italian journal of neurological sciences Pub Date : 1999-08-01 DOI: 10.1007/s100720050036

G Buccino, U Scoditti, M Pini, A R Tagliaferri, C Manotti, D Mancia

{"title":"Low-oestrogen oral contraceptives as a major risk factor for cerebral venous and sinus thrombosis: evidence from a clinical series.","authors":"G Buccino, U Scoditti, M Pini, A R Tagliaferri, C Manotti, D Mancia","doi":"10.1007/s100720050036","DOIUrl":"https://doi.org/10.1007/s100720050036","url":null,"abstract":"Cerebral venous and sinus thrombosis (CVST) is still considered a severe clinical problem that is difficult to diagnose and manage and is linked to a poor prognosis. Nonetheless, conventional cerebral angiography and magnetic resonance imaging (MRI), or more recently, MR angiography allow a more rapid and precise diagnosis, and prognosis has improved with the use of anticoagulant treatment. We report 23 cases of CVST consecutively admitted to the Institute of Neurology of the University of Parma during the period 1990-1997. In all cases diagnosis was confirmed by means of MRI or conventional angiography of brain vessels. Among the patients, 22 were female and 1 was male. In all patients, plasma levels of protein C, protein S, antithrombin III (ATIII) and antiphospholipid antibodies (APA) were evaluated. In 15 of 23 patients, the presence of factor V Leiden mutation was also determined, and found positive in 3 patients (20%). Of the 22 female patients, 15 (68%) were on low-oestrogen (containing less than 50 microg oestrogen) oral contraceptive (OC) treatment. This percentage of OC use by patients with CVST is much higher than that of the rest of the female Italian population. OC use was associated with the presence of factor V Leiden mutation in two cases, with a deficiency of protein C in 1 case and a deficiency of protein S in another.Whether low-oestrogen Ocs may induce cerebral thromboembolic events is an open matter. According to our data, it may be argued that Ocs, even if at low oestrogen content, represent a major risk factor for CVST. The use of Ocs, as is the case for systemic venous thromboembolic events, may further increase the risk of CVST in women carrying the factor V Leiden mutation or other inherited hyperthrombotic conditions.","PeriodicalId":73522,"journal":{"name":"Italian journal of neurological sciences","volume":"20 4","pages":"231-5"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s100720050036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21412251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Transcranial Doppler detection of microembolic signals: a review. 经颅多普勒检测微栓塞信号的研究进展。

Italian journal of neurological sciences Pub Date : 1999-06-01 DOI: 10.1007/s100720050025

M Del Sette, S Angeli, C Gandolfo

引用次数: 1