ISRN obstetrics and gynecology最新文献

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Ritodrine Should Be Carefully Administered during Antenatal Glucocorticoid Therapy Even in Nondiabetic Pregnancies. 在产前糖皮质激素治疗期间,即使是非糖尿病妊娠也应谨慎使用利托卡因。
ISRN obstetrics and gynecology Pub Date : 2013-01-01 Epub Date: 2013-02-28 DOI: 10.1155/2013/120735
Masaki Ogawa, Yoshio Matsuda, Aiko Kobayashi, Etsuko Shimada, Yoshika Akizawa, Minoru Mitani, Yasuo Makino, Hideo Matsui
{"title":"Ritodrine Should Be Carefully Administered during Antenatal Glucocorticoid Therapy Even in Nondiabetic Pregnancies.","authors":"Masaki Ogawa,&nbsp;Yoshio Matsuda,&nbsp;Aiko Kobayashi,&nbsp;Etsuko Shimada,&nbsp;Yoshika Akizawa,&nbsp;Minoru Mitani,&nbsp;Yasuo Makino,&nbsp;Hideo Matsui","doi":"10.1155/2013/120735","DOIUrl":"https://doi.org/10.1155/2013/120735","url":null,"abstract":"<p><p>Aim. Antenatal glucocorticoid therapy (AGT) has been commonly used recently. However, this therapy has severe harmful effects such as maternal hyperglycemia. In Japan, ritodrine hydrochloride has been used as a tocolytic agent. In this study, we performed retrospective casecontrol study to clarify whether concomitant use of ritodrine and glucocorticoid was safe to pregnant women without diabetes mellitus. Methods. We reviewed the computerized records of pregnant women with pregestational diabetes (n = 9) and nondiabetes (n = 45) who gave birth at our hospital between 2002 and 2011. Cases and controls received AGT. Blood glucose after the therapy was analyzed, and additional volume of insulin was compared to that before the therapy. Results. From this study, 30 units of insulin were necessary when performing AGT in diabetic pregnant women. And also, an increase in blood glucose of 40 mg/dL was seen after the therapy even in nondiabetic pregnant women. Blood glucose increased significantly in the group that also received ritodrine, and it was shown that the number of pregnant women who might develop ketoacidosis might increase 11-fold. Conclusions. Ritodrine should be carefully administered during antenatal glucocorticoid therapy. It may be necessary to adequately monitor blood glucose, when performing the therapy, even in nondiabetic pregnant women.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":" ","pages":"120735"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/120735","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40227418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Enhancement of ovarian malignancy on clinical contrast enhanced MRI studies. 卵巢恶性肿瘤的临床增强MRI检查。
ISRN obstetrics and gynecology Pub Date : 2013-01-01 Epub Date: 2013-02-13 DOI: 10.1155/2013/979345
Harpreet K Pannu, Weining Ma, Emily Craig Zabor, Chaya S Moskowitz, Richard R Barakat, Hedvig Hricak
{"title":"Enhancement of ovarian malignancy on clinical contrast enhanced MRI studies.","authors":"Harpreet K Pannu,&nbsp;Weining Ma,&nbsp;Emily Craig Zabor,&nbsp;Chaya S Moskowitz,&nbsp;Richard R Barakat,&nbsp;Hedvig Hricak","doi":"10.1155/2013/979345","DOIUrl":"https://doi.org/10.1155/2013/979345","url":null,"abstract":"<p><p>Purpose. To assess if there is a significant difference in enhancement of high grade serous carcinoma of the ovary compared with other ovarian malignancies on clinically performed contrast enhanced MRI studies. Methods. In this institutional-review-board-approved study, two radiologists reviewed contrast enhanced MRI scans in 37 patients with ovarian cancer. Readers measured the signal intensity (SI) of ovarian mass and gluteal fat pre- and postcontrast administration. Percentage enhancement (PE) was calculated as [(post-pre)/precontrast SI] × 100. Results. Pathology revealed 19 patients with unilateral and 18 patients with bilateral malignancies for a total of 55 malignant ovaries-high grade serous carcinoma in 25/55 ovaries (45%), other epithelial carcinomas in 12 ovaries (22%), nonepithelial cancers in 8 ovaries (14%), and borderline tumors in 10 ovaries (18%). Enhancement of high grade serous carcinoma was not significantly different from other invasive ovarian malignancies (Reader 1 P = 0.865; Reader 2 P = 0.353). Enhancement of invasive ovarian malignancies was more than borderline tumors but did not reach statistical significance (Reader 1P = 0.102; Reader 2 P = 0.072). Conclusion. On clinically performed contrast enhanced MRI studies, enhancement of high grade serous ovarian carcinoma is not significantly different from other ovarian malignancies.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"979345"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/979345","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31293886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Erratum to "robot-assisted radical hysterectomy for cervical cancer: review of surgical and oncological outcomes". 对“机器人辅助宫颈癌根治性子宫切除术:手术和肿瘤结果回顾”的勘误。
ISRN obstetrics and gynecology Pub Date : 2013-01-01 Epub Date: 2013-01-10 DOI: 10.1155/2013/305175
Renato Seracchioli, Mohamed Mabrouk, Serena Solfrini, Giulia Montanari, Giulia Ferrini, Giulia Giovanardi, Diego Raimondo, Riccardo Schiavina
{"title":"Erratum to \"robot-assisted radical hysterectomy for cervical cancer: review of surgical and oncological outcomes\".","authors":"Renato Seracchioli,&nbsp;Mohamed Mabrouk,&nbsp;Serena Solfrini,&nbsp;Giulia Montanari,&nbsp;Giulia Ferrini,&nbsp;Giulia Giovanardi,&nbsp;Diego Raimondo,&nbsp;Riccardo Schiavina","doi":"10.1155/2013/305175","DOIUrl":"https://doi.org/10.1155/2013/305175","url":null,"abstract":"Copyright © 2013 Renato Seracchioli et al. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In the paper titled \" Robot-Assisted Radical Hysterectomy for Cervical Cancer: Review of Surgical and Oncological Outcomes \" , all the authors' names and surnames are in reverse order. e authors list should be corrected as follows:","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"305175"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/305175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31324086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mayer-rokitansky-kuster-hauser syndrome: embryology, genetics and clinical and surgical treatment. meyer -rokitansky-kuster-hauser综合征:胚胎学、遗传学、临床和外科治疗。
ISRN obstetrics and gynecology Pub Date : 2013-01-01 Epub Date: 2013-02-04 DOI: 10.1155/2013/628717
Alfonsa Pizzo, Antonio Simone Laganà, Emanuele Sturlese, Giovanni Retto, Annalisa Retto, Rosanna De Dominici, Domenico Puzzolo
{"title":"Mayer-rokitansky-kuster-hauser syndrome: embryology, genetics and clinical and surgical treatment.","authors":"Alfonsa Pizzo,&nbsp;Antonio Simone Laganà,&nbsp;Emanuele Sturlese,&nbsp;Giovanni Retto,&nbsp;Annalisa Retto,&nbsp;Rosanna De Dominici,&nbsp;Domenico Puzzolo","doi":"10.1155/2013/628717","DOIUrl":"https://doi.org/10.1155/2013/628717","url":null,"abstract":"<p><p>Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a pathological condition characterized by primary amenorrhea and infertility and by congenital aplasia of the uterus and of the upper vagina. The development of secondary sexual characters is normal as well as that the karyotype (46,XX). Etiologically, this syndrome may be caused by the lack of development of the Müllerian ducts between the fifth and the sixth weeks of gestation. To explain this condition, it has been suggested that in patients with MRKH syndrome, there is a very strong hyperincretion of Müllerian-inhibiting factor (MIF), which would provoke the lack of development of the Müllerian ducts from primitive structures (as what normally occurs in male phenotype). These alterations are commonly associated with renal agenesis or ectopia. Specific mutations of several genes such as WT1, PAX2, HOXA7-HOXA13, PBX1, and WNT4 involved in the earliest stages of embryonic development could play a key role in the etiopathogenesis of this syndrome. Besides, it seems that the other two genes, TCF2 (HNF1B) and LHX1, are involved in the determinism of this pathology. Currently, the most widely nonsurgical used techniques include the \"Frank's dilators method,\" while the surgical ones most commonly used are those developed by McIndoe, Williams, Vecchietti, Davydov, and Baldwin.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"628717"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/628717","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31257129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 76
Air pollution metric analysis while determining susceptible periods of pregnancy for low birth weight. 空气污染指标分析,同时确定易受影响的孕期低出生体重。
ISRN obstetrics and gynecology Pub Date : 2013-01-01 Epub Date: 2013-01-30 DOI: 10.1155/2013/387452
Joshua L Warren, Montserrat Fuentes, Amy H Herring, Peter H Langlois
{"title":"Air pollution metric analysis while determining susceptible periods of pregnancy for low birth weight.","authors":"Joshua L Warren,&nbsp;Montserrat Fuentes,&nbsp;Amy H Herring,&nbsp;Peter H Langlois","doi":"10.1155/2013/387452","DOIUrl":"https://doi.org/10.1155/2013/387452","url":null,"abstract":"<p><p>Multiple metrics to characterize air pollution are available for use in environmental health analyses in addition to the standard Air Quality System (AQS) pollution monitoring data. These metrics have complete spatial-temporal coverage across a domain and are therefore crucial in calculating pollution exposures in geographic areas where AQS monitors are not present. We investigate the impact that two of these metrics, output from a deterministic chemistry model (CMAQ) and from a spatial-temporal downscaler statistical model which combines information from AQS and CMAQ (DS), have on risk assessment. Using each metric, we analyze ambient ozone's effect on low birth weight utilizing a Bayesian temporal probit regression model. Weekly windows of susceptibility are identified and analyzed jointly for all births in a subdomain of Texas, 2001-2004, and results from the different pollution metrics are compared. Increased exposures during weeks 20-23 of the pregnancy are identified as being associated with low birth weight by the DS metric. Use of the CMAQ output alone results in increased variability of the final risk assessment estimates, while calibrating the CMAQ through use of the DS metric provides results more closely resembling those of the AQS. The AQS data are still preferred when available.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"387452"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/387452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31257128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Genesis of preeclampsia: an epidemiological approach. 子痫前期的起源:流行病学方法。
ISRN obstetrics and gynecology Pub Date : 2012-01-01 Epub Date: 2012-02-08 DOI: 10.5402/2012/916914
Jaime Salvador-Moysén, Yolanda Martínez-López, José M Ramírez-Aranda, Marisela Aguilar-Durán, Alberto Terrones-González
{"title":"Genesis of preeclampsia: an epidemiological approach.","authors":"Jaime Salvador-Moysén, Yolanda Martínez-López, José M Ramírez-Aranda, Marisela Aguilar-Durán, Alberto Terrones-González","doi":"10.5402/2012/916914","DOIUrl":"10.5402/2012/916914","url":null,"abstract":"<p><p>THERE ARE ANALYZED SOME OF THE MAIN ASPECTS RELATED TO THE CAUSALITY OF PREECLAMPSIA, PRIVILEGING TWO TYPES OF MODELS: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2012 ","pages":"916914"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30540441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of First Trimester Ultrasonography before 11 Weeks of Gestation: A Retrospective Study. 妊娠11周前妊娠早期超声检查的应用:一项回顾性研究。
ISRN obstetrics and gynecology Pub Date : 2012-01-01 Epub Date: 2012-10-14 DOI: 10.5402/2012/308759
Sevki Celen, Necmiye Dover, Berna Seckin, Ufuk Goker, Okan Yenicesu, Nuri Danisman
{"title":"Utility of First Trimester Ultrasonography before 11 Weeks of Gestation: A Retrospective Study.","authors":"Sevki Celen,&nbsp;Necmiye Dover,&nbsp;Berna Seckin,&nbsp;Ufuk Goker,&nbsp;Okan Yenicesu,&nbsp;Nuri Danisman","doi":"10.5402/2012/308759","DOIUrl":"https://doi.org/10.5402/2012/308759","url":null,"abstract":"<p><p>We showed the utility of first trimester ultrasonography before 11 weeks of gestation for antenatal followup. We retrospectively analyzed 1295 records of patients who underwent first trimester ultrasonography (transvaginal/abdominal) in our antenatal clinic in Ankara, Turkey. Maternal age, parity, gestational age, and maternal gestational history were compared with ultrasonographic findings. Patients were divided into 12 groups based on ultrasonographic diagnoses in the first ultrasonographic scan, and called for a control examination within 10 days if the diagnostic findings were abnormal. The data were statistically analyzed using Kruskal-Wallis and chi-square tests. We noted 81.3% patients to have single, viable, intrauterine pregnancies, while 18.7% had abnormal or complicated pregnancies with uterine anomalies, ovarian cysts, fibroids, or subchorionic hematomas. Normal and anembryonic pregnancies had significantly lower median diagnostic period in the control ultrasonography than in the first examination. First trimester ultrasonography before 11 weeks of gestation is valuable in determining pregnancy outcomes.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2012 ","pages":"308759"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/308759","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31003717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Evaluation of Cytokines in Endocervical Secretion and Vaginal pH from Women with Bacterial Vaginosis or Human Papillomavirus. 细菌性阴道病或人乳头瘤病毒患者宫颈内膜分泌物和阴道pH值中细胞因子的评价
ISRN obstetrics and gynecology Pub Date : 2012-01-01 Epub Date: 2012-03-22 DOI: 10.5402/2012/342075
Ana Claudia Camargo Campos, Eddie Fernando Candido Murta, Márcia Antoniazi Michelin, Cleomenes Reis
{"title":"Evaluation of Cytokines in Endocervical Secretion and Vaginal pH from Women with Bacterial Vaginosis or Human Papillomavirus.","authors":"Ana Claudia Camargo Campos,&nbsp;Eddie Fernando Candido Murta,&nbsp;Márcia Antoniazi Michelin,&nbsp;Cleomenes Reis","doi":"10.5402/2012/342075","DOIUrl":"10.5402/2012/342075","url":null,"abstract":"<p><p>Objective. To verify the relationship between vaginal pH and human papillomavirus (HPV) infection and to measure cytokine levels in endocervical secretions of women with bacterial vaginosis (BV) or HPV. Methods. 173 women (16-48 years old) were enrolled and divided into groups: BV, HPV, and controls. Microbiological culture and vaginal pH were measured. HPV detect by PCR, and cytokines by ELISA (IL-2, IL-6, IL-10, IL-12, TNF-α, and IFN-γ cytokines). Results. Of 173 women, 60 were control group (34.7%) and 113 were distributed in HPV (n=36, 20.8%), BV (n=36, 20.8%), vaginitis (n=30, 17.3%) and, BV and HPV-associated groups (n=11, 6.4%). Vaginal pH > 4.5 was related with HPV infection. IL-2 and IL-12 were increased in BV and HPV groups, and IL-6 (only BV group), compared to control group. IL-12 and IFN-γ were higher in HPV than BV group. Conclusion. The increase of vaginal pH was associated with HPV infection; BV and HPV groups had a Th1 cytokines immune response.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2012 ","pages":"342075"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/342075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30586549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Early detection of maternal risk for preeclampsia. 早期发现孕妇子痫前期风险。
ISRN obstetrics and gynecology Pub Date : 2012-01-01 Epub Date: 2012-07-17 DOI: 10.5402/2012/172808
B Mikat, A Gellhaus, N Wagner, C Birdir, R Kimmig, A Köninger
{"title":"Early detection of maternal risk for preeclampsia.","authors":"B Mikat,&nbsp;A Gellhaus,&nbsp;N Wagner,&nbsp;C Birdir,&nbsp;R Kimmig,&nbsp;A Köninger","doi":"10.5402/2012/172808","DOIUrl":"https://doi.org/10.5402/2012/172808","url":null,"abstract":"<p><p>Preeclampsia is one of the leading causes of maternal and fetal morbidity and mortality. New molecular insights offer new possibilities of early diagnosis of elevated maternal risk. Maternal risk factors, biophysical parameters like Doppler examination of the uterine arteries and biochemical parameters allow early risk calculation. Preventive and effective therapeutic agents like acetylsalicylacid can be started in the early second trimester. This article reviews the diagnostic possibilities of early risk calculation to detect women having high risk for preeclampsia and the potential benefits for them, the offspring and health care systems. We provide risk calculation for preeclampsia as an important and sensible part of first trimester screening.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2012 ","pages":"172808"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/172808","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30804737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Symptoms and risk factors of ovarian cancer: a survey in primary care. 卵巢癌的症状和危险因素:一项初级保健调查。
ISRN obstetrics and gynecology Pub Date : 2012-01-01 Epub Date: 2012-08-23 DOI: 10.5402/2012/754197
Ketan Gajjar, Gemma Ogden, M I Mujahid, Khalil Razvi
{"title":"Symptoms and risk factors of ovarian cancer: a survey in primary care.","authors":"Ketan Gajjar,&nbsp;Gemma Ogden,&nbsp;M I Mujahid,&nbsp;Khalil Razvi","doi":"10.5402/2012/754197","DOIUrl":"https://doi.org/10.5402/2012/754197","url":null,"abstract":"<p><p>In spite of the increased awareness of ovarian cancer symptoms, the predictive value of symptoms remains very low. The aim of this paper is to obtain the views of general practitioners (GPs) in relation to symptom-based detection of ovarian cancer and to assess their knowledge for family history of breast and/or ovarian cancer as a predisposing factor for ovarian cancer. In this questionnaire survey, postal questionnaires were sent to 402 GPs in 132 primary care clinics, out of which we obtained 110 replies (27.4%). Approximately 26% of respondent GPs thought that the symptoms were more likely to be frequent, sudden, and persistent, and one-fifth were unsure of the importance of family history of breast cancer in relation to ovarian cancer. The participant GPs scored a set of symptoms for their relevance to ovarian cancer from 0 (not relevant) to 10 (most relevant). The highest scored symptoms were abdominal swelling (mean ± SD, 8.19 ± 2.33), abdominal bloating (7.01 ± 3.01), and pelvic pain (7.46 ± 2.26). There was a relative lack of awareness for repetitive symptoms as well as gastrointestinal symptoms as an important feature in a symptom-based detection of ovarian cancer.</p>","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2012 ","pages":"754197"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/754197","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30887996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
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