International journal of oral implantology (Berlin, Germany)最新文献

{"title":"Echo-guided soft tissue harvesting: A novel approach identifying tissue thickness, density, vascularisation and a safe harvesting zone in the palatal region.","authors":"Leonardo Mancini, Lorenzo Tavelli, Shayan Barootchi, Ronald E Jung, Daniel S Thoma","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To utilise high-frequency ultrasound echo intensity as a method for identifying a safe harvesting zone and assessing tissue thickness, density and vascularisation in the palatal region for soft tissue harvesting.</p><p><strong>Materials and methods: </strong>Four consecutive patients requiring soft tissue augmentation were recruited. Optical scans were taken and imported into design software, where customised guides were developed based on the patient's palatal anatomy and the harvesting zone. The guides were tailored to fit the shape of the ultrasound probe. They were 3D printed and allowed for a standardised examination of the palate, the identification of a safe harvesting zone and the evaluation of tissue thickness, quality and vascularisation using high-frequency ultrasound. Following these steps and using an echo-harvesting guide, a de-epithelialised free gingival graft was obtained, ensuring preservation of the main vascular flow while avoiding fatty or glandular tissues.</p><p><strong>Results: </strong>In all four cases, high-frequency ultrasound scans were successfully obtained and the mean measured soft tissue thickness increased from 3.2 mm (anterior) to 6.0 mm (posterior), with a mean transversal increase from 0.9 to 6.0 mm. Ultrasound imaging revealed a layer of hypoechogenic fatty/glandular tissue located 3 to 4 mm beneath the epithelial layer. Using colour Doppler analysis, the vascular flow was identified and mapped to help design a safe harvesting zone. The tissue density, evaluated using a grayscale analysis, showed hypoechogenicity corresponding to fatty/glandular tissues and areas with blood vessels, whereas dense connective tissue appeared isoechoic. This differentiation allowed for precise localisation of the safe harvesting zone, an optimal zone for connective tissue harvesting, while ensuring that regions with higher fat/glandular content and/or large vascular structures were avoided.</p><p><strong>Conclusion: </strong>The echo-guided harvesting approach is a promising technique for soft tissue palatal harvesting, enabling clinicians to identify a standardised safe zone away from major blood vessels when assessing tissue quality and quantity. This approach enhances surgical precision and control, and facilitates preoperative planning for alternative treatments when graft size or tissue quality or quantity are inadequate due to proximity to the greater palatine artery. It is crucial to note that a learning curve is required to interpret the obtained images accurately and integrate this tool into daily clinical practice.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 2","pages":"169-179"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indications, techniques and complications associated with full-arch rehabilitation using trans-sinus implants: A systematic review and prevalence meta-analysis.","authors":"Francesco Gianfreda, Donato Antonacci, Filiberto Mastrangelo, Carlo Raffone, Leonardo Mancini, Maria Scarpati Cioffari di Castiglione, Vito Carlo Alberto Caponio, Patrizio Bollero","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the failure rate of trans-sinus implants for full-arch rehabilitation in atrophic maxillae, comparing their outcomes to those achieved with axial and tilted implants.</p><p><strong>Materials and methods: </strong>The review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, including studies where patients underwent rehabilitation with trans-sinus implants alone or in combination with axial or zygomatic implants. The review was registered on the International Prospective Register of Systematic Reviews (ID: CRD42024537320). A meta-analysis using Haldane and hybrid corrections compared failure rates between implant types.</p><p><strong>Results: </strong>Out of 2,359 articles, 10 studies employing trans-sinus implants were selected. In the meta-analysis, the trans-sinus group was composed of 232 implants, 5 of which failed, compared to 5 of the 675 implants in the axial/tilted group. There were no statistically significant differences in failure rate between the groups (RRHaldane = 2.80, 95% confidence interval 0.89 to 8.77, P = 0.076; RRHybrid = 2.74, 95% confidence interval 0.91 to 8.17, P = 0.070). The pooled analysis indicated a comparable success rate.</p><p><strong>Conclusions: </strong>Trans-sinus implants represent a viable alternative, in terms of survival rate, to axial/tilted implants for rehabilitation of the atrophic maxilla, minimising the need for invasive procedures such as extensive bone grafting; however, further controlled clinical trials with longer follow-up periods are needed to confirm these results.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 2","pages":"105-116"},"PeriodicalIF":2.5,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Peri-implant tissue stability: The PROS concept.","authors":"Jonathan Misch, Abdusalam E Alrmali, Pablo Galindo-Fernandez, Muhammad H A Saleh, Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The following amendments are made to the published article: Int J Oral Implantol 2025;18(1):73-84; First published 17 March 2025.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 2","pages":"181-183"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time to get back in the game.","authors":"Craig M Misch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 2","pages":"95-96"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recombinant human platelet-derived growth factor-BB-mediated reconstructive therapy of advanced peri-implantitis bone defects: A case series.","authors":"Alberto Monje, Ramón Pons, Shayan Barootchi, Muhammad H A Saleh, Paul S Rosen, Anton Sculean","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The treatment of advanced peri-implantitis-related bone defects is often associated with ineffective efforts to halt disease progression. The objective of this case series was to evaluate the performance of reconstructive therapy for the management of advanced peri-implantitis using recombinant human platelet-derived growth factor-BB as an adjunctive biological agent.</p><p><strong>Materials and methods: </strong>A prospective case series study on advanced intrabony peri-implantitis bone defects (≥ 50% bone loss) was performed. Clinical and radiographic variables were collected at baseline (after non-surgical therapy) and 12 months after surgical treatment. Implant surface decontamination of the intrabony component was carried out using titanium brushes and the electrolytic method. Before grafting, recombinant human platelet-derived growth factor-BB was applied on the implant surface. A mixture of mineralised allograft and xenograft hydrated with recombinant human platelet-derived growth factor-BB and covered by a collagen barrier membrane was used for reconstructive therapy. Disease resolution was defined as an absence of bleeding on probing, pocket depth 6 mm and no radiographic evidence of progressive bone loss. Descriptive statistics were performed to assess the effect of treatment on the clinical and radiographic variables.</p><p><strong>Results: </strong>A total of 10 patients exhibiting 13 advanced peri-implantitis-related bone defects were included. Implant survival at the 1-year follow-up was 100%. No major complications occurred during the early healing phase. All the clinical parameters, with the exception of keratinised mucosa, and radiographic parameters yielded statistical significance. In particular, mean pocket depth decreased by 4.5 mm and the mean Sulcus Bleeding Index was reduced by 1.8. Radiographic intrabony defects displayed a significantly narrower, shallower and less angled configuration at the 1-year follow-up. The disease resolution rate at implant level was 61.5%.</p><p><strong>Conclusion: </strong>The surgical reconstructive strategy involving the use of recombinant human platelet-derived growth factor-BB proved to be safe and effective for treating advanced peri-implantitis-related bone defects.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"47-57"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-implant tissue stability: The PROS concept.","authors":"Jonathan Misch, Abdusalam E Alrmali, Pablo Galindo-Fernandez, Muhammad H A Saleh, Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This manuscript introduces a concept that aims to optimise peri-implant health and ensure stability of peri-implant tissues in dental implant therapy. It encompasses the principles of platform switching, restorative abutment design, optimal (internal conical) connection and subcrestal implant placement, and is thus referred to as the PROS concept. Platform switching involves strategic repositioning of the implant-abutment junction to contain inflammatory infiltrate, whereas restorative abutment design emphasises the importance of abutment height and contour in peri-implant tissue stability. Optimal (internal conical) connection focuses on minimising micromovements to reduce microgaps and enhancing stability, and subcrestal placement explores the benefits of implant placement depth on peri-implant tissue health. By integrating these principles, clinicians can enhance the predictability of peri-implant bone stability, leading to successful outcomes in dental implant therapy. This clinical guideline has been developed in accordance with the Appraisal of Guidelines for Research and Evaluation, ensuring methodological rigour and transparency, and enhancing its credibility and usability in clinical practice.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"73-84"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saving teeth versus dental implant replacement: A concerning trend.","authors":"Craig M Misch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of peri-implant keratinised mucosa on implant health: An umbrella systematic review with evidence mapping and quantitative meta-meta-analysis.","authors":"Hamoun Sabri, Lorenzo Tavelli, Asfandyar Tariq Sheikh, Khushboo Kalani, Khoa Huang, Jacob Martin Zimmer, Hom-Lay Wang, Shayan Barootchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To conduct a comprehensive umbrella review to synthesise existing evidence and critically evaluate the significance of keratinised mucosa width in peri-implant health and assess the consistency and heterogeneity among previous systematic reviews on this topic.</p><p><strong>Materials and methods: </strong>A comprehensive search strategy was implemented across multiple databases. Eligible studies were screened and data were extracted. Methodological quality was assessed using A MeaSurement Tool to Assess systematic Reviews version 2, and strength of evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation criteria. A meta-meta-analysis using Hedges' g as the effect size measure was performed to investigate the outcomes of implant therapy in patients with (control) and without adequate keratinised mucosa width (case).</p><p><strong>Results: </strong>Ten systematic reviews, published between 2012 and 2023, were included. Significant effect sizes were found for mucosal recession, Gingival Index/modified Gingival Index, modified Plaque Index and marginal bone loss. Specifically, narrow keratinised mucosa width ( 2 mm) was associated with increased mucosal recession (equivalent odds ratio 4.05, P = 0.03), higher Gingival Index/modified Gingival Index scores (equivalent odds ratio 3.131, P = 0.001), elevated modified Plaque Index scores (equivalent odds ratio 5.34, P = 0.005) and greater marginal bone loss (equivalent odds ratio 1.852, P = 0.0007). No significant associations were observed for bleeding on probing, pocket depth changes or pocket depth values. Follow-up time did not have a significant effect on these outcomes.</p><p><strong>Conclusions: </strong>Inadequate keratinised mucosa width ( 2 mm) correlated with increased mucosal recession, higher Gingival Index/modified Gingival Index, Plaque Index/modified Plaque Index scores and greater marginal bone loss. However, there is still a lack of sufficient evidence indicating the impact on bleeding on probing, pocket depth, implant survival and disease prevalence (no significant association or insufficient evidence).</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"13-30"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implant dislocation into the maxillary sinus after 30 years of loading due to peri-implantitis: A case report.","authors":"Tristan Hampe, Fouad Khoury","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>Dislocation of implants into the maxillary sinus typically occurs during surgery or in the early postoperative period. This case study presents an instance of implant dislocation that occurred after 30 years under functional loading due to peri-implantitis.</p><p><strong>Materials and methods: </strong>An 87-year-old woman presented with a loosened fixed partial denture, revealing a missing implant in the maxillary left second molar site upon clinical examination. The patient showed no symptoms of sinusitis. Imaging confirmed the dislocation of the implant, along with a pathological radiodensity filling the sinus. Maxillary sinus revision was performed via a bone lid under conscious sedation. The implant was removed along with a polypous mass, and the latter was sent for pathological examination. Following debridement, disinfection (3% hydrogen peroxide, photodynamic decontamination) was performed. The oroantral fistula was closed through double-layer closure with a pedicled connective tissue flap and a mucoperiosteal flap. Two months after surgery, sinus floor elevation using the layering technique and implant placement were performed. After 3 months, the implants were exposed, and the restoration was placed 6 weeks later.</p><p><strong>Results: </strong>Histopathological examination confirmed chronic sinusitis with the presence of polyps. A 2-month follow-up CBCT scan revealed a healthy sinus with an open ostium. Subsequent procedures went uneventfully.</p><p><strong>Conclusions: </strong>Progressive peri-implantitis in the posterior maxilla can lead to the dislocation of dental implants into the sinus and subsequent chronic sinusitis. Removing the implant through a bone lid from the lateral sinus wall with simultaneous sinus revision is an effective way to treat this condition and allows for later bone grafting and implant placement.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"59-68"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary stability of immediate implants placed in fresh sockets in comparison with healed sites: A systematic review and meta-analysis.","authors":"Isabella Harb Bizzi, Taciane Menezes da Silveira, Fernando Valentim Bitencourt, Francisco Wilker Mustafa Gomes Muniz, Juliano Cavagni, Tiago Fiorini","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aimed to compare the primary stability of immediate implants placed in fresh sockets to implants placed in healed sites.</p><p><strong>Materials and methods: </strong>A systematic search was conducted of the PubMed, Scopus, Web of Science, Embase, Clinicaltrials.gov and Cochrane databases, and the grey literature. The risk of bias was assessed using the Risk of Bias 2 and Risk of Bias In Non-randomized Studies of Interventions tools (both Cochrane Collaboration, London, UK). Primary stability was assessed through resonance frequency analysis (implant stability quotient) and insertion torque. Subgroup analyses were performed to investigate factors that impact the outcome. Meta-analyses of mean difference were conducted using random-effects models. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach. The study was registered in the International Prospective Register of Systematic Reviews (no. CRD42022304379).</p><p><strong>Results: </strong>Out of 2,317 studies published up to and including January 2024, 4 randomised and 5 non-randomised studies were included, representing 438 individuals with a total of 515 implants (265 in healed sites and 250 placed immediately). Seven studies were included in the meta-analysis of implant stability quotient and showed an overall mean difference of 5.66 (95% confidence interval 1.52 to 9.79), favouring the healed sites group. Implant torque meta-analysis did not present statistical differences (mean difference 4.22; 95% confidence interval -1.04 to 9.51). Concerning the subgroup analyses, higher stability was seen in the immediate implant placement group for wider implants. In conventional implants, the difference in implant stability quotient was 8.09 (95% confidence interval 3.43 to 12.75). The certainty of evidence was very low for both analyses.</p><p><strong>Conclusion: </strong>Higher primary stability was achieved in the healed sites group, with statistical significance but unclear clinical relevance; however, wider implants appeared to counter the lower stability of implants placed immediately. Due to the very low certainty of evidence, the results should be interpreted with caution.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"18 1","pages":"33-44"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}