{"title":"Pulsed dye laser (PDL) versus photodynamic therapy (PDT) for the treatment of port wine stain (PWS): a systematic review and meta-analysis","authors":"Yi-Di Liu, Ying Wang, Jing Zeng, Hui Li, Hai-Xia Qiu, Ying Gu","doi":"10.1097/jd9.0000000000000352","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000352","url":null,"abstract":"Objective: Vascular lesions, such as port wine stain (PWS), lead to facial and psychological problems that require careful and timely treatments. This review aims to compare two mainstream methods pulsed dye laser (PDL) therapy and photodynamic therapy (PDT) for PWS. Methods: The Cochrane Library, PubMed, Embase, CNKI Full-Text Chinese Database and VIP Chinese Scientific Journals Database were searched for literatures comparing PDL versus PDT in treating PWS with no dates set. Studies were eligible for inclusion if they were randomised, placebo-controlled or head-to-head trials published in either English or Chinese. The primary outcome was overall response rate judged by physician/investigator-reported outcome scoring system. Adverse effects were also recorded. Review Manager (RevMan) was used to perform data synthesis. Cochrane risk of bias tool was used for methodological quality assessment. Retrospective studies were assessed based on Newcastle-Ottawa Scale. Results: Twelve studies met the inclusion criteria, among which eight studies had the data necessary for the meta-analysis. Among the eight studies, four were retrospective studies with 1,075 patients. The other four were RCT studies with 532 randomised participants. Regarding the overall response rate of RCT studies, PDT demonstrated no significantly higher efficacy than PDL with RR 0.76 (95% credible interval [CI] 0.48–1.20). Regarding purple types, the overall response rate of PDT was statistically significantly superior to that of PDL with RR of 0.47 (95% CI: 0.29–0.79). In terms of red types, PDT also manifested no significantly higher efficacy compared with PDL with RR of 0.85 (95% CI : 0.27–2.71). Conclusion: PDT is an effective and safe treatment for different types of PWS and was more effective than PDL in treating purple type of PWS.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136181955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wen-Jia Nie, Xin-Yue Zhang, Yu-Ting Xia, Bi-ling Jiang, Zhen Cai, Yan Liu, Ayan Hasen, Juan Tao, Yan Li
{"title":"Murine Models of Infantile Hemangioma: A Comprehensive Review","authors":"Wen-Jia Nie, Xin-Yue Zhang, Yu-Ting Xia, Bi-ling Jiang, Zhen Cai, Yan Liu, Ayan Hasen, Juan Tao, Yan Li","doi":"10.1097/jd9.0000000000000351","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000351","url":null,"abstract":"Infantile hemangioma is the most common benign vascular tumor of infancy and is characterized by a unique life cycle. Animal models that reflect the histological and biological characteristics of infantile hemangioma are critical tools for preclinical studies. Various infantile hemangioma animal models have been developed and improved during the past few decades. However, very few reports have provided practical suggestions for selecting a suitable animal model based on the study purpose. This comprehensive review summarizes the construction methods and application scenarios of different models. The advantages and disadvantages of each model are fully discussed, providing a reference for choosing the most applicable animal model for infantile hemangioma-associated research.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"68 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136182867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrated skin microbiome and metabolome analyses reveal altered bacterial community composition and metabolites in psoriasis","authors":"Rong Tao, Zhe Wan, Ruo-Yu Li, Ruo-Jun Wang","doi":"10.1097/jd9.0000000000000350","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000350","url":null,"abstract":"Objective: Current theories highlight the role of the microbiome in the pathogenesis of psoriasis. Additionally, abnormal metabolism can alter disease processes in terms of occurrence, progression, and prognosis. Therefore, an integrative microbiome and metabolome analysis of the skin may aid in understanding the disease pathogenesis and identify therapeutic targets for psoriasis. Methods: We recruited 22 patients with psoriasis and 22 age- and sex-matched healthy controls. Skin swabs were collected from the participants’ scalps. All samples underwent amplicon sequencing of the ITS1 and V3V4 16S rRNA regions and metabolome analysis. Results: The psoriatic lesions were characterized by higher bacterial diversity, significantly higher abundances of Corynebacterium and Staphylococcus , and a lower abundance of Cutibacterium compared with healthy controls. However, no significant alterations in the fungal diversity or fungal taxonomies were detected. Metabolome analysis revealed that prostaglandin-related metabolites, nucleotides, and cysteine- and methionine-related metabolites were significantly enriched in patients with psoriasis, and these metabolites were positively correlated with the disease-associated bacteria Staphylococcus and Corynebacterium . Conclusions: We demonstrated significant alterations in the skin microbiome and metabolome in patients with psoriasis compared with healthy controls.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136182868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and validation of diagnostic criteria for elderly atopic dermatitis","authors":"Shang-Shang Wang, Zheng Li, Chao-Ying Gu, Hui-Bin Yin, Yue-Meng Wu, Xu Yao, Wei Li","doi":"10.1097/jd9.0000000000000349","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000349","url":null,"abstract":"Objective: Elderly atopic dermatitis (AD) is a newly identified subtype of AD. Whether specific diagnostic criteria are needed for elderly AD has been debated. This study aimed to propose diagnostic criteria for elderly AD and evaluate the sensitivity. Methods: A hospital-based study was conducted. We screened the clinical features of 1312 patients with AD of different ages in one cohort and proposed a set of diagnostic criteria for elderly AD. The criteria were then validated in another cohort of 223 patients clinically diagnosed with elderly AD by dermatologists specialized in AD to examine the diagnostic sensitivity compared with other criteria by chi-square test. Results: Based on the patients’ clinical features, a set of diagnostic criteria for elderly AD were proposed. The new diagnostic criteria showed significantly higher sensitivity than the classical diagnostic criteria (P<0.001), especially for mild and moderate AD (P<0.001). Of all 223 patients with elderly AD, 93.3% fulfilled our criteria, while only 43.5%, 65.5%, and 52.0% fulfilled the Hanifin and Rajka criteria, the Japanese Dermatology Academy criteria, and the United Kingdom Working Party criteria, respectively. Conclusion: The newly proposed criteria for elderly AD yielded high diagnostic sensitivity, particularly for mild and moderate AD.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136182703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shivali Devjani, Ogechi Ezemma, Kristen J. Kelley, Maryanne Makredes Senna
{"title":"Platelet-Rich Plasma for Androgenetic Alopecia: What the Dermatologist Needs to Know","authors":"Shivali Devjani, Ogechi Ezemma, Kristen J. Kelley, Maryanne Makredes Senna","doi":"10.1097/jd9.0000000000000348","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000348","url":null,"abstract":"Devjani, Shivali1; Ezemma, Ogechi1; Kelley, Kristen J.1; Senna, Maryanne Makredes1,2 Author Information","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136058030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah-Jane Dempsey, Louise K. Andersen, Sarah J. Coates, Mark D.P. Davis
{"title":"Impact of Climatic Factors on Varicella-Zoster Viral Infection","authors":"Sarah-Jane Dempsey, Louise K. Andersen, Sarah J. Coates, Mark D.P. Davis","doi":"10.1097/jd9.0000000000000347","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000347","url":null,"abstract":"Dempsey, Sarah-Jane; Andersen, Louise K. MD; Coates, Sarah J. MD; Davis, Mark D.P. MD Author Information","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An extensive review of vitiligo-associated conditions","authors":"Madhavi Premkumar, Iyshwarya Bhaskar Kalarani, Vajagathali Mohammed, Ramakrishnan Veerabathiran","doi":"10.1097/jd9.0000000000000346","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000346","url":null,"abstract":"Vitiligo is an autoimmune disorder caused by the destruction of melanocytes in various body regions. Numerous diseases may accompany vitiligo. The prevalence of vitiligo varies among geographical regions and shows no relation to sex or age. However, vitiligo most commonly affects people aged 10 to 30 years. The clinical symptoms of vitiligo include irregular patches on the skin and various diseases associated with this disorder. The present review focuses on the clinical effects and risk factors of vitiligo-associated conditions and the current therapeutics for treating vitiligo. This systematic review was performed based on the PRISMA guidelines and articles published from 2000 to 2023 in several electronic databases (Web of Science, PubMed, PsycINFO, and others). The most clinically significant diseases associated with vitiligo are alopecia areata, autoimmune thyroid disease, Addison's disease, and type 1 diabetes mellitus. No targeted population is specifically prone to vitiligo; it does not affect any particular race or sex. Hence, awareness of the diseases associated with vitiligo is necessary to control them through various medical and surgical treatments with the proper facilities.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135152885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexa J Cohen, Laura K Gleason, Safiyyah A Bhatti, Neda Nikbakht
{"title":"Neutrophilic panniculitis associated with myelodysplastic syndrome/myeloproliferative neoplasm: a case report and literature review.","authors":"Alexa J Cohen, Laura K Gleason, Safiyyah A Bhatti, Neda Nikbakht","doi":"10.1097/jd9.0000000000000286","DOIUrl":"10.1097/jd9.0000000000000286","url":null,"abstract":"<p><strong>Introduction: </strong>Neutrophilic panniculitis (NP) is a rare subtype of neutrophilic dermatosis, a group of neutrophil-rich inflammatory skin disorders that can present in association with myeloid neoplasms. NP is defined by the presence of a neutrophilic infiltrate in the fat lobules of the subcutis in the absence of either infection or vasculitis. We herein describe a 65-year-old woman with a recent diagnosis of myelodysplastic syndrome/myeloproliferative neoplasm overlap syndrome (MDS/MPN) who abruptly developed painful, pruritic nodules consistent with NP.</p><p><strong>Case presentation: </strong>A 65-year-old woman with MDS/MPN presented for evaluation of painful and pruritic nodules on her upper and lower extremities. A biopsy revealed a lobular neutrophilic infiltrate in the subcutis without evidence of microorganisms or vasculitis. The patient was diagnosed with NP and treated with oral prednisone. Within 1 month of treatment, she reported complete resolution of the nodules.</p><p><strong>Discussion: </strong>Similar to other neutrophilic dermatoses, NP may arise in association with hematologic malignancies of myeloid origin, such as MDS/MPN. A literature review revealed that most cases of NP associated with MDS occur after the onset of MDS and respond to systemic corticosteroids, not antibiotics. Infection should be ruled out before initiating treatment with systemic steroids.</p><p><strong>Conclusion: </strong>Although the mechanism is still unknown, it is important for clinicians to be aware that NP is associated with MDS; thus, hematological malignancies should be investigated upon diagnosis of NP. Once diagnosed, NP is easily treated and has an excellent response to systemic corticosteroids.</p>","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"6 3","pages":"168-171"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41161656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of Whole Blood Zinc Levels, CD4 Cell Count, Disease Stage, and Dermatologic Manifestations Among HIV Patients: A Single Center Experience in Philippines: Erratum","authors":"","doi":"10.1097/jd9.0000000000000322","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000322","url":null,"abstract":"","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135434197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiology of leprosy in China, 2021: an update","authors":"Ying Shi, Pei-Wen Sun, Le Wang, Hong-Sheng Wang, Mei-Wen Yu, Heng Gu","doi":"10.1097/jd9.0000000000000344","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000344","url":null,"abstract":"Objective: To describe the epidemiological characteristics of leprosy in China in 2021 and provide essential information for future national leprosy control and prevention strategies. Methods: We collected epidemiological data of leprosy from 31 provinces, autonomous regions, and municipalities of China (except for Hong Kong, Macao, and Taiwan) provided by the Leprosy Management Information System. We performed a comparative analysis of the epidemiological features of patients with leprosy including age, sex, geographical distribution, and grade of disability. Results: In total, 374 newly detected leprosy cases were reported nationwide in China in 2021, giving an incidence rate of 0.27 per million population, which represented a decrease of 7.9% compared with 2020. Among the population with leprosy in 2021 that comprised 238 males (63.6%) and 136 females (36.4%), 1.9% (7/374) were children younger than 15 years, 92.8% (347/374) had multibacillary leprosy, and 18.2% (68/374) had grade 2 disability. More than half of the new leprosy cases (54.8%, 205/374) were distributed in southwest China. There were 33 relapsed leprosy cases reported in 2021. By the end of 2021, there were 1,897 registered leprosy cases reported nationwide, giving a prevalence rate of 1.35 per million population. Conclusion: The leprosy epidemic in China shows a downward trend in terms of the prevalence and incidence rates. However, the high prevalence of leprosy in southwest China is still a matter of concern.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135990885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}