International journal of dermatology and venereology最新文献

{"title":"2-Deoxy-D-glucose as an HK2 inhibitor for chronic eczema: From bioinformatics discovery to animal validation","authors":"Li-Lan Luo, Jianjun Gong, Kun Cao, Wanlu Zhao, Teng-Jian Wang, Yue Wu, Zhe-Yuan Lin, Qingshan Ma, Tian Li, Luping Qin, Quanlong Zhang","doi":"10.1097/jd9.0000000000000440","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000440","url":null,"abstract":"Objective: Chronic eczema (CE) features dry, itchy skin, while its pathogenesisis unclear. This study was aimed to identify key genes and potential prospective drugs for CE pathogenesis. Methods: Clinical microarray dataset - GSE63741 from Gene Expression Omnibus database was chosen to identify differentially expressed genes (DEGs) in CE. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes and Gene set enrichment analysis analyses were conducted to explore the relationships of the DEGs, and a protein-protein interactions network was built using STRING database. Connectivity Map (CMap) analyses were carried out to identify candidate compounds. CE model mice were induced by dinitrochlorobenzene for therapeutic evaluation. The tissue levels of interleukin (IL) -4 and tumor necrosis factor (TNF) -α in mice ears and the serum levels of TNF-α, IL-4, IL-6, and IFN-γ were assessed by immunohistochemistry, respectively. Western blotting was employed to assay the Enolase 2 (ENO2) and Hexokinase Ⅱ (HK2) expression. One-way ANOVA revealed significant differences among groups, followed by Tukey’s post hoc test for pairwise comparisons. Results: A total of 94 DEGs were identified, comprising 48 upregulated genes and 46 downregulated genes. The Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed that the DEGs were primarily influenced by the IL-17, Staphylococcus aureus infection, and estrogen signaling pathway. The protein-protein interactions network consisted of 30 hub genes, 586 edges, and 79 nodes. In the Gene set enrichment analysis analyses, the DEGs were predominantly involved in signaling pathways related to IL-2, IL-6, interferon (IFN)-γ, and IFN-α. The connectivity Map analysis identified 2-deoxy-D-glucose (2-DG) as a potential therapeutic agent for CE. In the therapeutic evaluation, the 2-DG-treated mice exhibited significantly reduced epidermal thickness, inflammatory cell infiltration, and right ear weight compared with the model mice, with dose-dependence. Moreover, 2-DG exerted anti-inflammatory effects by inhibiting the expression of pro-inflammatory cytokines TNF-α, IL-6, IFN-γ (Model vs. 4% 2-DG, TNF-α, 1,208 ± 39.92 ng/L vs. 1,040.44 ± 36.92 ng/L; IL-6, 179.81 pg/mL ± 7.13 vs . 153.44 ± 5.95 pg/mL; IFN-γ, 1,225.58 ± 52.72 ng/L vs. 1,028.29 ± 55.23 ng/L, all P < 0.001,) and increasing the expression levels of IL-4 in both the ear tissue and serum (Model vs. 4% 2-DG, 135.45 ± 12.21 pg/mL vs. 227.42 ± 8.44 pg/mL, P <0.001). 2-DG also reduced the protein expressions of ENO2 (Model vs. 4% 2-DG, 0.99 ± 0.16 vs. 1.55 ± 0.02, P < 0.001) and HK2 (Model vs. 4% 2-DG, 1.97 ± 0.22 vs. 2.37 ± 0.06, P = 0.024) in the ear tissue. Conclusions: This study revealed the key gene networks and core pathways of CE through bioinformatics analysis, and verified that the glycolytic inhibitor 2-DG significantly alleviated CE symptoms by regulating the expression of inflammatory factors and metabolic enzymes in mice models, providing a basi","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Serum Interleukin-15 in Patients With Psoriasis: A Prospective Case-Control Study","authors":"Nagat Sobhy, Hanaa Donia, Aya Farouk, Ahmed Abdel-Bary","doi":"10.1097/jd9.0000000000000420","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000420","url":null,"abstract":"Objective: Interleukin (IL)-15, a pro-inflammatory cytokine, has been shown to be upregulated in various autoimmune and inflammatory disorders. Although its relationship with pathogenesis of psoriasis is unclear, this research aimed to assess the possible role of IL-15 in the pathogenesis of psoriasis and its correlation with the disease severity. Methods: Fifty patients with chronic plaque psoriasis were selected for this case–control study at Alexandria Main University Hospital from December 2022 to January 2024. Clinical evaluation of the patients was achieved through the calculation of the Psoriasis Area and Severity Index score. Serum IL-15 levels were measured by enzyme linked immunosorbent assay. The Mann–Whitney test was employed for abnormally distributed quantitative variables. The Spearman coefficient test was applied for comparisons of two abnormally distributed quantitative variables. Results: The mean serum IL-15 Level in the patient group (482.90 ng/mL [Q1 = 440.63, Q3 = 525.16]) was significantly higher than that in the control group (410.25 ng/mL [Q1 = 310.23, Q3 = 430.35]) ( P < 0.001). Furthermore, the serum IL-15 level had a significant positive correlation with the Psoriasis Area and Severity Index score ( P = 0.049). Conclusion: The level of IL-15 may indicate the severity of disease in the patients with psoriasis, and IL-15 has the potential to be a clinical biomarker and therapeutic target of psoriasis, which needs more in-depth studies to further clarify.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"8 2","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147901387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metformin Alleviates DNCB-Induced Contact Dermatitis in vivo and in vitro by Inhibiting Necroptosis of Keratinocytes","authors":"Si-Han Chen, Zi-Zhen Zhou, Ni Lian, Yujie Chen, Fangyuan Long, Min Li, Heng Gu, Xu Chen","doi":"10.1097/jd9.0000000000000416","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000416","url":null,"abstract":"Objective: Metformin is a well-known anti-diabetic drug that has also been reported to alleviate various inflammatory diseases. However, whether metformin can mitigate contact dermatitis and the underlying mechanisms remain unknown. Therefore, we conducted these in vitro and in vivo experiments to investigate the therapeutic effects of metformin on 2,4-dinitrochlorobenzene (DNCB)–induced contact dermatitis. Methods: The animal model used in the experiment was DNCB-induced contact dermatitis model, and HaCaT cells were used for in vitro experiments. Animal experiments were conducted in randomized groups. Patch tests were conducted to evaluate the irritation caused by different concentrations of metformin on mouse skin, and determined the optimal metformin concentration for following experiments. Propidium iodide staining was used to label dead cells, and western blotting was performed to assess changes in protein levels following metformin treatment. Immunofluorescence experiments were used to compare phosphorylated mixed lineage kinase domain-like protein levels before and after topical metformin administration in a DNCB-induced contact hypersensitivity mouse model. Data from the 2 groups were analyzed using the t test, and for comparisons involving 3 or more groups, a one-way analysis of variance was used. Results: In a DNCB-induced contact hypersensitivity mouse model, topical application of 4.0% metformin significantly alleviated skin inflammation (the dermatitis score reduced from 9.83 ± 0.29 to 5.17 ± 0.76, P < 0.05), and reduced the proportion of dead cells from 46.83% ± 9.25% to 9.77% ± 9.54% ( P < 0.05), and reduced phosphorylation levels of mixed lineage kinase domain-like protein in keratinocytes. In vitro experiments further demonstrated that metformin inhibited necroptosis in HaCaT cells under a contact dermatitis–like environment simulated by tumor necrosis factor-α and interferon-γ. Conclusions: These findings suggest that metformin inhibits keratinocyte necroptosis, thereby alleviating inflammation in contact dermatitis. The topical application of metformin may represent a potential therapeutic approach for contact dermatitis, which needs further in vitro and in vivo experiments for investigation.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"8 3","pages":"125-133"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of 30% supramolecular salicylic acid combined with ultra-pulse carbon dioxide fractional laser therapy on facial atrophic acne scars","authors":"Xiu-Feng Liu, Man-Chang Yu","doi":"10.1097/jd9.0000000000000394","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000394","url":null,"abstract":"\u0000 \u0000 To assess the impact of 30% supramolecular salicylic acid (SSA) combined with ultra-pulse carbon dioxide (CO2) fractional laser therapy on facial atrophic acne scars.\u0000 \u0000 \u0000 \u0000 This retrospective study included patients with atrophic acne scars treated from June 2020 to June 2022. The patients were divided into the combination group (SSA combined with ultra-pulse CO2 fractional laser therapy) and the laser group (ultra-pulse CO2 fractional laser therapy alone). Four treatment sessions were conducted for each group. Follow-up visits were performed every 2 months after each treatment and included assessments of the Échelle d'Évaluation clinique des cicatrices d'acné (ECCA) score, effective rate, and visual analogue scale score.\u0000 \u0000 \u0000 \u0000 The combination and laser groups comprised 72 and 61 patients, respectively. There were no significant differences in sex, age, or baseline ECCA score between the two groups. The effective rate (95.8% vs. 67.2%, P < 0.001) was higher and the pain scores (during and after the intervention) were lower in the combination group than in the laser group (P < 0.001). The severity of erythema, edema, and crusting was milder in the combination group (P < 0.001). The proportion of highly satisfied patients was higher (73.6% vs. 31.2%, P < 0.001) and the Dermatology Life Quality Index showed greater improvement (0.15 ± 0.40 vs. 1.39 ± 1.53, P < 0.001) in the combination group than in the laser group.\u0000 \u0000 \u0000 \u0000 The combination of ultra-pulse CO2 fractional laser therapy and 30% supramolecular SSA had improved efficacy in treating facial atrophic acne scars without increasing pain or inducing adverse reactions.\u0000","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"124 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and Content Validity of Health Games for children with Atopic Dermatitis","authors":"Mariana Muzzolon, Mariana A Pasa Morgan, R. Imoto, Vânia O de Carvalho","doi":"10.1097/jd9.0000000000000396","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000396","url":null,"abstract":"\u0000 \u0000 The success of managing atopic dermatitis (AD) largely depends on patient adherence to treatment. Achieving adherence requires more than knowledge transfer; it also requires a change in patients’ health behavior. Therefore, we conducted this study to develop and validate the content of health games for the pediatric population with AD.\u0000 \u0000 \u0000 \u0000 This study focused on developing and validating the content of health games about AD. Among these were the book Oli e o Grande Desafio da Coceira™ (“Oli and the Great Itching Challenge”) and the games Dermatrilha™ (“Dermatrail”) and Caixinha Surpresa da Dermatite™ (“Dermatitis Surprise Box”). The instrument development process consisted of five stages: planning of the instruments, development of the instruments, development of content validation questionnaires, evaluation by an expert committee, and a pre-test with the target audience.\u0000 \u0000 \u0000 \u0000 The expert committee comprised 20 professionals: 5 pediatric dermatologists, 5 hospital psychologists, 5 illustrators/designers, and 5 early childhood education teachers. The target audience comprised 25 children with AD aged 5 to 12 years. The content validity index was 0.94 in the evaluation by the expert committee and 0.95 in the evaluation by the target audience. Among the games, the general content validity index was 0.95 among the members of the expert committee and 0.92 among the target audience, being higher than 0.80 for all items.\u0000 \u0000 \u0000 \u0000 The health games evaluated in this study are useful psychoeducational tools with high content validity for use in the therapeutic education of children with AD.\u0000","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":" October","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis and immune infiltration analysis of m6A RNA methylation regulators in cutaneous melanoma and differential analysis with cuproptosis related genes","authors":"Cui-cui Tian, Hao-ze Shi, Cong-cong Zhang, Yingjie Kong, Hao Chen","doi":"10.1097/jd9.0000000000000387","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000387","url":null,"abstract":"\u0000 \u0000 N6-methyladenosine (m6A) modification and cuproptosis play essential roles in the pathogenesis of various malignant tumors. However, the predictive role of m6A regulators and cuproptosis-related genes in cutaneous melanoma (CM) remains unclear. In this study, the aim was not only to explore the role of m6A modification in CM, but also to investigate the differential expression of cuproptosis-related genes in different risk group.\u0000 \u0000 \u0000 \u0000 We obtained transcriptome data from the XENA and GTEx databases. Univariate Cox regression analysis was performed to investigate the relationship between m6A-related genes and the outcomes of CM. LASSO regression analysis was utilized to construct a risk model. Moreover, we analyzed immune cell infiltration using CIBERSORT algorithms. Finally, we evaluated the expression levels of cuproptosis-related genes in CM samples and performed RT-qPCR to validate the expression of cuproptosis-associated genes in melanoma cells after YTHDF3 knockdown.\u0000 \u0000 \u0000 \u0000 All m6A-related genes differed in melanoma tissues and normal tissues and a prognostic signature was developed. Immune infiltration revealed that low-risk group patients had a higher level of CD8 + T cells, memory activated CD4 + T cells, activated NK cells and M1 Macrophages than high-risk group (P<0.05). Moreover, the cuproptosis-related genes MTF-1, PDHB and FDX1 were significantly negatively associated with risk score (P=0.0007, P=0.0057 and P=0.04, respectively). We also found that downregulation YTHDF3 in melanoma cells affected the expression of cuproptosis-related genes. (P<0.01 and P<0.05).\u0000 \u0000 \u0000 \u0000 Our study demonstrated the prognostic value of m6A-related genes and cuproptosis-related genes in CM, providing new predictive models and potential therapeutic targets for CM.\u0000","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141272055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress on ultrastructure of Treponema pallidum subspecies pallidum","authors":"Si-Ning Wang, Rui-Li Zhang","doi":"10.1097/jd9.0000000000000386","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000386","url":null,"abstract":"The ultrastructure of Treponema pallidum, the causative pathogen of syphilis, remains unclarified because of the difficulty of long-term culture in vitro. However, research on the ultrastructure of T. pallidum has made great progress in recent years with the success of long-term culture of T. pallidum in vitro and the development of gene sequencing technology and electron microscopy. This review summarizes the research progress on the ultrastructure of T. pallidum.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":" 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on the epidemiology of hand-foot-and-mouth disease and varicella in a general hospital in Guangzhou, China","authors":"Hui-Hui Wu, Hang Li, Juan-Hua Liu, Lu-Li Song, D. Luo, Yu-Kun Zhao","doi":"10.1097/jd9.0000000000000383","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000383","url":null,"abstract":"We retrospectively reviewed the medical records of patients with hand-foot-and-mouth disease (HFMD) and varicella treated in a general hospital in Guangzhou, China between 2017 and 2023 to evaluate the effect of the coronavirus disease 2019 (COVID-19) on the epidemiology of HFMD and varicella in Guangzhou. The epidemiological characteristics of HFMD and varicella before (2017–2019), during (2020–2022), and after (2023) the pandemic were compared. In total, 1731 cases of HFMD and 1043 cases of varicella were reported before the COVID-19 pandemic (2017–2019), with average reporting rates of 0.08% and 0.05%, respectively. During the COVID-19 pandemic (2020–2022), the number of reported cases of HFMD and varicella decreased to 571 and 389, respectively, with average reporting rates of 0.03% and 0.02%, respectively, which were significantly different from those in the pre-pandemic period (P < 0.001). In the post-pandemic period (2023), the reporting rate of HFMD was 0.07%, showing a marked increase compared with that in 2022 (P < 0.001). However, the difference in the reporting rate of varicella in 2023 did not differ significantly from that in 2022 (P =0.204). These results suggest that non-pharmaceutical interventions implemented during the COVID-19 pandemic might be helpful in preventing the spread of HFMD and varicella.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"50 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eruptive pseudoangiomatosis and parvovirus: exclusive clinical findings","authors":"F. Gaudiello, S. Spennato, F. Cillo, Maria Teresa Cantelli, Maria Vastarella, M. Scalvenzi","doi":"10.1097/jd9.0000000000000384","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000384","url":null,"abstract":"\u0000 \u0000 Eruptive pseudoangiomatosis (EP) is a rare type of cutaneous exanthema characterized by red angioma-like papules. An association of EP with viral infection has been reported.\u0000 We herein describe four pediatric patients who showed a new variant of EP-associated rash with atypical clinical features and positivity for parvovirus B19 infection.\u0000 \u0000 \u0000 \u0000 Pediatric patients showed a new variant of EP-associated rash with atypical clinical features and positivity for parvovirus B19 infection by dermoscopy and reflectance confocal microscopy. The papules were localized to the face and characteristic perilesional halo was absent.\u0000 In all patients, serology revealed evidence of active infection by parvovirus B19.\u0000 \u0000 \u0000 \u0000 Few cases of a facial pseudoangiomatous rash that is related to parvovirus B19 infection and lacks the typical anemic halo have been reported in the literature.\u0000 \u0000 \u0000 \u0000 These cases provide new data on the clinical spectrum of EP and its association with parvovirus.\u0000","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":"52 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrophage Polarization and Crosstalk between Macrophages and Other Cells in Hidradenitis Suppurativa","authors":"Qiujing Zhang, Yibo Feng, Xiang Chen, Xiaohui Mo, Qiong Wu, Qiang Ju","doi":"10.1097/jd9.0000000000000382","DOIUrl":"https://doi.org/10.1097/jd9.0000000000000382","url":null,"abstract":"Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic inflammatory disease characterized by the development of inflammatory nodules, abscesses, and pus-discharging tunnels in areas such as the axillary, inguinal, gluteal, and perianal regions. The pathogenesis of HS remains unclear, but it is being increasingly recognized to rely on the dysregulation of inflammatory responses. Central to this process are macrophages, which have emerged as key players in the inflammatory milieu of HS. These cells orchestrate inflammation via polarization and significantly influence the functions of neighboring cells. This review briefly describes macrophage polarization and crosstalk between macrophages and other cells in patients with HS with the aim of providing new therapeutic strategies for the clinical management of HS.","PeriodicalId":73440,"journal":{"name":"International journal of dermatology and venereology","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}