{"title":"Ultradian Hemodynamics and Autonomic-Central Nervous System Activity During Sleep: A Pilot Study with Insights for Hypertension","authors":"D. Shannahoff-Khalsa, Roy Schult, B. Sramek","doi":"10.1089/imr.2021.0031","DOIUrl":"https://doi.org/10.1089/imr.2021.0031","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42204215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gunpreet Kaur, P. Bansal, Ravinder Sharma, Amar Nath, Vikas Gupta
{"title":"A Market Basket Folklore Survey of Ethnobotanical Usage of Plants for Treatment of Mumps in North India","authors":"Gunpreet Kaur, P. Bansal, Ravinder Sharma, Amar Nath, Vikas Gupta","doi":"10.1089/imr.2022.0071","DOIUrl":"https://doi.org/10.1089/imr.2022.0071","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42002626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michiko Onuma, K. Tomooka, I. Saito, K. Maruyama, Den-ichiro Yamaoka, T. Tanigawa
{"title":"Association Between the Electroconductive Value at 24 Acupoints and Blood Pressure in Community-Dwelling Japanese: The Toon Health Study","authors":"Michiko Onuma, K. Tomooka, I. Saito, K. Maruyama, Den-ichiro Yamaoka, T. Tanigawa","doi":"10.1089/imr.2022.0008","DOIUrl":"https://doi.org/10.1089/imr.2022.0008","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47222850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joji Suzuki, Bianca Martin, Sara Prostko, Peter R Chai, Roger D Weiss
{"title":"Cannabidiol Effect on Cue-Induced Craving for Individuals with Opioid Use Disorder Treated with Buprenorphine: A Small Proof-of-Concept Open-Label Study.","authors":"Joji Suzuki, Bianca Martin, Sara Prostko, Peter R Chai, Roger D Weiss","doi":"10.1089/imr.2022.0070","DOIUrl":"https://doi.org/10.1089/imr.2022.0070","url":null,"abstract":"<p><strong>Background: </strong>Opioid use disorder (OUD) remains a major public health concern. Despite the use of medications for OUD such as buprenorphine, the current gold-standard treatment, relapse in the context of increased craving remains common. Cannabidiol (CBD) has been shown to reduce cue-induced craving in individuals with OUD, but among those who were not receiving any buprenorphine treatment. This small proof-of-concept open-label study sought to evaluate the effect of CBD on cue-induced craving among individuals with OUD who were being actively treated with buprenorphine.</p><p><strong>Methods: </strong>Participants (<i>n</i> = 5) received CBD (Epidiolex<sup>®</sup>) 600 mg once daily for 3 consecutive days in an open-label manner. Primary outcome was cue-induced craving measured on a visual analog scale of 0 to 10, calculated as the difference in craving in response to drug-related versus neutral cues. The cue-reactivity paradigm was performed at baseline before CBD administration, and was repeated after 3 days of CBD. Secondary outcomes included scores on depression, anxiety, pain, opioid withdrawal, and side effects.</p><p><strong>Results: </strong>All participants were actively taking buprenorphine for an average of 37.8 months (range 1-120 months). Cue-induced craving was significantly lower after CBD dosing compared with baseline (0.4 vs. 3.2, paired <i>t</i>-test, <i>p</i> = 0.0046). No significant changes in scores for depression, anxiety, pain, or opioid withdrawal were noted. CBD was well tolerated, although one participant experienced moderate sedation; otherwise, no other adverse effects were reported.</p><p><strong>Conclusions: </strong>Given the high risk for bias in a small uncontrolled open label study such as this, results must be interpreted with caution. A larger adequately powered trial with a suitable control group is needed to confirm the finding that CBD may help to reduce cue-induced craving among individuals with OUD currently on buprenorphine treatment. Research should further evaluate whether adjunctive use of CBD can improve clinical outcomes for individuals with OUD maintained on buprenorphine. ClinicalTrials.gov (NCT04192370).</p>","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":"157-163"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40355957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brittany Guidos, M. V. van Zuilen, D. Murphy, Andrea Luce, Joni Calvario
{"title":"Integrative Medicine in Timor-Leste: A Report of Prevalence and Practice of Timorese Medicine Usage Alongside Conventional Health Care","authors":"Brittany Guidos, M. V. van Zuilen, D. Murphy, Andrea Luce, Joni Calvario","doi":"10.1089/imr.2021.0008","DOIUrl":"https://doi.org/10.1089/imr.2021.0008","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46468968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christine Farag, Laurie C. Caines, Helen Wu, Mingda Sun, M. Guerrera
{"title":"Familiarity with Complementary and Alternative Medicine: A Multimodal Curriculum in Medical Education","authors":"Christine Farag, Laurie C. Caines, Helen Wu, Mingda Sun, M. Guerrera","doi":"10.1089/imr.2022.0024","DOIUrl":"https://doi.org/10.1089/imr.2022.0024","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42261579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Anti-Viral Activity of Prunella vulgaris: A Narrative Review","authors":"W. Mak, S. Walsh","doi":"10.1089/imr.2022.0045","DOIUrl":"https://doi.org/10.1089/imr.2022.0045","url":null,"abstract":"Introduction: This narrative review reports on the anti-viral activity of Prunella vulgaris with the aim of providing an overview of P. vulgaris research to date. P. vulgaris is an aromatic perennial herb that is common across diverse geographic regions. This article includes information about the investigation strategies and methodologies used to identify the nature of P. vulgaris’ s anti-viral mechanisms. Given its diverse interest and use, the P. vulgaris literature over the previous three decades reports on the phytochemical, agricultural, and pharmacological uses of the herb. To provide some background to the review, a brief description of the life cycle of the virus is given. Materials and Methods: The review was based on a literature search with three databases: Embase, Medline, and PubMed. The review’s inclusion criteria were unrestricted: The time of publication was unlimited; the keywords included ‘‘virus,’’ along with HIV and HSV (given the research’s historical focus), and ‘‘prunella vulgaris’’ (and variations). The articles identified were then categorized. Results: The search identified 24 articles, with 10 articles on human immunodeficiency virus (HIV), 8 articles on herpes simplex virus (HSV), and the remainder on other viruses. In vitro experimental designs dominated the methods, whereas in vivo parts were also noted. Most frequent P. vulgaris extraction methods included boiling for aqueous extract, followed by ethanolic extraction. Several anti-viral effective chemicals were identified across the studies, including polysaccharides, polyphenolics, triterpenes, and a range of essential oils. In this review, the articles were then categorized according to the stages of viral development and analysis methods, such as time-of-addition, pseudo-typing, and the use of reverse transcriptase, integrase, protease, and viral protein detecting kits. This categorization exposed the mechanisms behind the anti-viral influenza-like diseases, other than P. vulgaris, can be the candidates for further investigations. Volatile compounds from these herbs are also good targets, which may be proved to yield fruitful results.","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49384088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Novielli, Karin Cinalioglu, A. Potes, Zoes Thomas, Joseph Inhaber, Marouane Nassim, Susanna G. Torres-Platas, L. Morin, J. Drapeau, Rebecca Fox, Suzanne Rouleau, Aileen Castro, M. Segal, K. Looper, S. Rej
{"title":"Tai Chi/Qigong in Adults with Depression and Anxiety: A Pilot Retrospective Study","authors":"Julia Novielli, Karin Cinalioglu, A. Potes, Zoes Thomas, Joseph Inhaber, Marouane Nassim, Susanna G. Torres-Platas, L. Morin, J. Drapeau, Rebecca Fox, Suzanne Rouleau, Aileen Castro, M. Segal, K. Looper, S. Rej","doi":"10.1089/imr.2021.0023","DOIUrl":"https://doi.org/10.1089/imr.2021.0023","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45771840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer S Mascaro, Almira Catic, Meha Srivastava, Maggie Diller, Shaheen Rana, Cam Escoffery, Viraj Master
{"title":"Examination of Provider and Patient Knowledge, Beliefs, and Preferences in Integrative Oncology at a National Cancer Institute-Designated Comprehensive Cancer Center.","authors":"Jennifer S Mascaro, Almira Catic, Meha Srivastava, Maggie Diller, Shaheen Rana, Cam Escoffery, Viraj Master","doi":"10.1089/imr.2021.0004","DOIUrl":"10.1089/imr.2021.0004","url":null,"abstract":"<p><strong>Purpose: </strong>The use of integrative approaches for symptom management is highly prevalent among patients undergoing cancer treatment and among cancer survivors and is increasingly endorsed by clinical practice guidelines. However, access to and implementation of integrative oncology (IO) approaches are hindered by barriers at multiple levels, including logistic, geographic, financial, organizational, and cultural barriers. The goal of this mixed-method study was to examine oncology provider and patient knowledge, beliefs, and preferences in IO to identify facilitators, barriers, and recommendations for implementation of IO modalities.</p><p><strong>Materials and methods: </strong>Data sources included patient surveys and provider semistructured interviews. Patients were in active treatment (<i>n</i> = 100) and survivors (<i>n</i> = 100) of heterogeneous cancer types. Patient and survivor surveys interrogated: (1) interest in types of IO approaches; and (2) preferences for delivery modality, frequency, and location. Providers (<i>n</i> = 18) were oncologists and nurse navigators working with diverse cancer types. Interviews queried their knowledge of and attitudes about IO, about their patients' needs for symptom management, and for recommendations for implementation of IO approaches in their clinic. We used the Consolidated Framework for Implementation Research framework to systematically analyze provider interviews.</p><p><strong>Results: </strong>The primary interests reported among actively treated patients and survivors were massage therapy, acupuncture, and wellness/exercise. Most patients expressed interest in both group and individual sessions and in telehealth or virtual reality options. Emergent themes from provider interviews identified barriers and facilitators to implementing IO approaches in both the internal and external settings, as well as for the implementation process.</p><p><strong>Conclusion: </strong>The emphasis on mind-body interventions as <i>integrative</i> rather than <i>alternative</i> highlights the importance of interventions as evidence-based, comprehensive, and integrated into health care. Gaining simultaneous perspectives from both patients and physicians generated insights for the implementation of IO care into complex clinical systems within a comprehensive cancer center.</p>","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":"1 1","pages":"66-75"},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9083429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Shokrani, J. Lukaszuk, David A. Walker, Heidi McCann, Elim Kim
{"title":"Assessment of Intake of Cinnamon Supplements on Hemoglobin A1c Levels in Prediabetics","authors":"M. Shokrani, J. Lukaszuk, David A. Walker, Heidi McCann, Elim Kim","doi":"10.1089/imr.2021.0018","DOIUrl":"https://doi.org/10.1089/imr.2021.0018","url":null,"abstract":"","PeriodicalId":73395,"journal":{"name":"Integrative medicine reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48625988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}