Global surgery (London)最新文献

{"title":"Video-assisted thoracoscopic thymectomy for early-stage thymoma: A review","authors":"S. Takeo, F. Shoji, G. Toyokawa, Yuka Kozuma, K. Yamazaki","doi":"10.15761/gos.1000208","DOIUrl":"https://doi.org/10.15761/gos.1000208","url":null,"abstract":"","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67466701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical management of malignant gastric gist with organ sparing surgery","authors":"G. Soni, B KumarKrishna, Asma Khalife, B. Telang, Deepak Ranvir, R. Joshi","doi":"10.15761/gos.1000210","DOIUrl":"https://doi.org/10.15761/gos.1000210","url":null,"abstract":"","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67466981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exceptional long-term survivor (12 years) with metastatic gallbladder cancer","authors":"F. Sacchetti, F. Ardito, Fabio M. Vecchio, F. Giuliante","doi":"10.15761/gos.1000213","DOIUrl":"https://doi.org/10.15761/gos.1000213","url":null,"abstract":"We present a rare case of exceptional long-term survival (12 years) in a 78-year-old female patient presenting with stage IVb Gallbladder Carcinoma (GBC) with an unusual site of metastasis (left supraclavicular lymph node). After chemotherapy, a metabolic response of the metastatic regional and left supraclavicular lymph nodes was documented during the follow-up for 10 years. Because of biliary colic onset due to the presence of stones in the gallbladder, surgical resection was planned. In order to perform a curative resection, the patient underwent bi-segmentectomy 4b-5 en-bloc with the gallbladder + regional lymphadenectomy, 12 years after GBC diagnosis. At pathology, a G2 pT2 adenocarcinoma of the gallbladder was confirmed with pathologic response in all the 5 retrieved regional lymph nodes. Franco Sacchetti1, Francesco Ardito1*, Fabio M Vecchio2 and Felice Giuliante1 1Catholic University of the Sacred Heart, Italy 2Department of Pathology, Catholic University of the Sacred Heart, Italy","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67467092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to harvest free fibula flap for mandibular reconstruction? Practical tips and tricks","authors":"C. Singh, Rajeev Kumar, P. Sakthivel","doi":"10.15761/GOS.1000204","DOIUrl":"https://doi.org/10.15761/GOS.1000204","url":null,"abstract":"","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67466242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constipation in infant with premature birth story may point out colonic stricture","authors":"Ezer S Serin","doi":"10.15761/gos.1000202","DOIUrl":"https://doi.org/10.15761/gos.1000202","url":null,"abstract":"","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67466582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic osteomyelitis in Sub-Saharan Africa—A Review","authors":"K. Olivier, Uwizeyimana Eugene, L. Lynn, Lucero-Prisno Don Eliseo III","doi":"10.15761/gos.1000207","DOIUrl":"https://doi.org/10.15761/gos.1000207","url":null,"abstract":"Background: Chronic osteomyelitis (COM) has remained an orthopaedic clinical challenge for many decades. It poses a socio-economic burden to patients and the health care system. We conducted this study to understand the epidemiological and clinical features of COM in Sub-Saharan Africa (SSA). Methods: A database-based search was done through PubMed, Google Scholar and Bioline for articles focusing on the epidemiology and clinical features of COM in SSA. Thirty-three articles were considered in the study based on the standards of assessing the level of evidence. Analysis and synthesis of the articles were conducted. Results: The incidence of COM in SSA is far greater than high income countries. Tibia is the commonly affected bone with more than 30% of cases, while the peak age is between the interval 10-21 years of age. Sickle cell disease, peripheral vascular disease, diabetes mellitus, Buluri ulcers and septicemia were reported as potential risk factors in SSA. 5093% of patients present with sinus drainage whereas Staphylococcus Aureus is the causative agent in 60-80% of the cases. Standard radiography and CT scan remain useful diagnostic tools in this region. The curative therapy involves radical surgical infection control with adjunct reconstructive procedures and antibiotherapy. Conclusion: COM remains on the rise in SSA. This trend is in line with the rise in exogenous osteomyelitis, road traffic injuries in addition to factors like patient characteristics, ignorance and poverty. Adolescents are more affected where immunosuppressive and vaso-occlusive disorders are main risk factors. We recommend extension of research on COM to overcome scarcity of data seen.","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67467049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspective Randomized-controlled clinical trial in patients submitted to self-expanding metal stents for colo-rectal cancer with bowel obstruction. Single center experience. Preliminary data","authors":"S. Giungato, L. Fazzolari, A. Deluca, R. Palazzo, M. Ferrante, A. Asciano, F. Marangolo, A. Brunetti, D. Gm, C. Dimito, Pepe As","doi":"10.15761/gos.1000212","DOIUrl":"https://doi.org/10.15761/gos.1000212","url":null,"abstract":"Introduction: Since the early 1990s, self- expanding metal stents (SEMS) have been used to treat malignant colonic obstruction. This kind of endoscopic procedure is mostly used for palliative treatment of colo-rectal cancer buti it is also used as “bridge to surgery”. Materials and methods: This perspective randomized-controlled clinical trial was performed from January 2017 to October 2019. We have recruited all patients admitted in our Emergency Hospital with diagnosis of colonic obstruction. All patients submitted to CT-scan. Patients was divided in 3 Groups: Group A (control group, composed by patients submitted only to emergency surgery) were 17; Group B (patients submitted to SEMS positioning and surgery) were 10; Group C (patients submitted to only SEMS positioning) were 14. The same Metal stent was used for all patient submitted to SEMS positioning (Colonic WallflexTM Boston Scientific 9 cm). Results: Analysis of comparison between Group A vs B highlighted statistical significance for diverting stoma performe (p-value: one-tailed 0.00035; two-tailed 0.00075; p<0.001), equal 70,5% of patients (12 out of 17). Also the comparison between Group A and B, in relation of survival rate (13 patients out of 17, equal to 70,58% in Group A and 10 patients out of 10, equal to 100%, in Group B after two years follow-up), statistical significance shows (p-value one-tailed 0.0010; two- tailed; p<0.005). Comparison of Group B plus C (24 patients), submitted to SEMS, shows time procedure was 25,17 minutes (range 10 - 40) and nobody patients showed stent dislocation or bowel obstruction signs after 48 h from endoscopic procedure. 1 case of Tenesmo in rectal SEMS and 2 colonic perforation after 73 days and 15 days (8%). They submitted early food intake. In our clinical controlled trial, even if is a preliminary data, demonstred that SEMS positioning is a the best palliative procedure with high success rate (95,8%) and a good survival. Mean days of hospitalization of 3,4 days. Conclusion: Our clinical randomized trial shows that SEMS positioning is feasibility as palliative therapy for obstructive colo-rectal cancer and it’s safe procedure as “bridge to surgery”. Other patients are ruled but a greater follow-up will be necessary to make our study more effective.","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67467086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver targeted therapies for hepatocellular carcinoma prior to transplant: contemporary management strategies.","authors":"Mustafa Nazzal,&nbsp;Sameer Gadani,&nbsp;Abdullah Said,&nbsp;Mandy Rice,&nbsp;Obi Okoye,&nbsp;Ahmad Taha,&nbsp;Krista L Lentine","doi":"10.15761/GOS.1000171","DOIUrl":"https://doi.org/10.15761/GOS.1000171","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) is an aggressive neoplastic disease that has been rapidly increasing in incidence. It usually occurs in the background of liver disease, and cirrhosis. Definitive therapy requires surgical resection. However, in majority of cases surgical resection is not tolerated, especially in the presence of portal hypertension and cirrhosis. Orthotopic liver transplant (OLT) in well selected candidates has been accepted as a viable option. Due to a relative scarcity of donors compared to the number of listed recipients, long waiting times are anticipated. To prevent patients with HCC from dropping out from the transplant list due to progression of their disease, most centers utilize loco-regional therapies. These loco-regional therapies(LRT) include minimally invasive treatments like percutaneous thermal ablation, trans-arterial chemoembolization, trans-arterial radio-embolization or a combination thereof. The type of therapy or combination used is determined by the size and location of the HCC and Barcelona Clinic Liver Cancer (BCLC) classification. The data regarding the efficacy of LRT in reducing post-transplant recurrence or disease-free survival is limited. This article reviews the available therapies, their strengths, limitations, and current use in the management of patients with hepatocellular carcinoma awaiting transplant.</p>","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958916/pdf/nihms945074.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40537992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One single drug combination of bromelain and Boswellia serrata casperome®: effects on postoperative Edema in open incisional abdominal hernia repair. Prospective randomized clinical trial","authors":"D. Gm, Tromba A, De Luca A, Franzoso L, Aubed A, Serinelli F, Giungato S","doi":"10.15761/gos.1000214","DOIUrl":"https://doi.org/10.15761/gos.1000214","url":null,"abstract":"Introduction: Aim of this study is to investigate the significant postoperative benefits on patients about edema of tissues after incisional hernia repair with synthetic mesh using a combination of Bromelain (200 mg) and Boswellia Serrata Casperome® (200 mg), evaluated by ultrasound (US), and compared to control patients group (not treated with drugs). Material and method: From May 2018 to May 2019, fifty adult patients submitted to onlay incisional hernia repair using synthetic mesh with component separation of the abdominal wall and were divided into two homogenous groups (27 females, 23 males, mean age 61 years, mean BMI 32). Only the treated group took one tablet of drug for 30 days on an empty stomach, starting from the first post-surgery day. Checks were made on all patients from the first post-surgery day and going on 15th, 30th and 60th post-surgery days by US linear probe measuring edema, defining its thickness and average diameter. Results: The two groups were homogeneous compared to the initial diameter of the abdominal wall defect (p=0.877). Therefore, the edema thickness was independent of the size of the starting defect in the two groups examined. The edema was already reduced in the treated group compared to the control group at 15 post-surgery days; therefore this reduction became statistically significant starting from US result at 30 post-surgery days of drug treatment (p=0.043) and was even greater in the US result after 60 post-surgery days (p=0.001). Conclusion: Results obtained in this preliminary study showed a rapid and significant improvement in postoperative edema outcome of incisional hernia repair in patients treated with drug. Benefits of treatment are also found in patients even after one month of drug suspension.","PeriodicalId":73175,"journal":{"name":"Global surgery (London)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67466620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}