Exceptional long-term survivor (12 years) with metastatic gallbladder cancer

F. Sacchetti, F. Ardito, Fabio M. Vecchio, F. Giuliante
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Abstract

We present a rare case of exceptional long-term survival (12 years) in a 78-year-old female patient presenting with stage IVb Gallbladder Carcinoma (GBC) with an unusual site of metastasis (left supraclavicular lymph node). After chemotherapy, a metabolic response of the metastatic regional and left supraclavicular lymph nodes was documented during the follow-up for 10 years. Because of biliary colic onset due to the presence of stones in the gallbladder, surgical resection was planned. In order to perform a curative resection, the patient underwent bi-segmentectomy 4b-5 en-bloc with the gallbladder + regional lymphadenectomy, 12 years after GBC diagnosis. At pathology, a G2 pT2 adenocarcinoma of the gallbladder was confirmed with pathologic response in all the 5 retrieved regional lymph nodes. Franco Sacchetti1, Francesco Ardito1*, Fabio M Vecchio2 and Felice Giuliante1 1Catholic University of the Sacred Heart, Italy 2Department of Pathology, Catholic University of the Sacred Heart, Italy
转移性胆囊癌的特殊长期幸存者(12年)
我们报告一位78岁的女性患者,其IVb期胆囊癌(GBC)有一个不寻常的转移部位(左侧锁骨上淋巴结),但有罕见的长期生存(12年)。化疗后,在10年的随访中记录了转移性区域和左侧锁骨上淋巴结的代谢反应。由于胆囊结石引起胆绞痛,计划手术切除。为了进行根治性切除,患者在GBC诊断后12年接受了4b-5双节段切除术,胆囊+局部淋巴结切除术。病理证实为胆囊G2 pT2腺癌,所有5个切除的区域淋巴结均有病理反应。Franco Sacchetti1, Francesco Ardito1*, Fabio M Vecchio2和Felice Giuliante1 1意大利圣心天主教大学2意大利圣心天主教大学病理学系
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