Gastrointestinal disorders (Basel, Switzerland)最新文献_第4页

Crosstalk between Gut Microbiota and Hepatocellular Carcinoma 肠道菌群与肝细胞癌之间的串扰

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-04-04 DOI: 10.3390/gidisord5020013

Chencheng Xie, C. Pocha

引用次数: 1

Evaluation of Structured, Semi-Structured, and Free-Text Electronic Health Record Data to Classify Hepatitis C Virus (HCV) Infection 结构化、半结构化和自由文本电子健康记录数据对丙型肝炎病毒（HCV）感染分类的评估

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-03-31 DOI: 10.3390/gidisord5020012

A. Fong, Justin M. Hughes, Sravya Gundapenini, Benjamin Hack, Mahdi Barkhordar, S. Huang, Adam J. Visconti, Stephen J Fernandez, D. Fishbein

{"title":"Evaluation of Structured, Semi-Structured, and Free-Text Electronic Health Record Data to Classify Hepatitis C Virus (HCV) Infection","authors":"A. Fong, Justin M. Hughes, Sravya Gundapenini, Benjamin Hack, Mahdi Barkhordar, S. Huang, Adam J. Visconti, Stephen J Fernandez, D. Fishbein","doi":"10.3390/gidisord5020012","DOIUrl":"https://doi.org/10.3390/gidisord5020012","url":null,"abstract":"Evaluation of the United States Centers for Disease Control and Prevention (CDC)-defined HCV-related risk factors are not consistently performed as part of routine care, rendering risk-based testing susceptible to clinician bias and missed diagnoses. This work uses natural language processing (NLP) and machine learning to identify patients who are at high risk for HCV infection. Models were developed and validated to predict patients with newly identified HCV infection (detectable RNA or reported HCV diagnosis). We evaluated models with three types of variables: structured (structured-based model), semi-structured and free-text notes (text-based model), and all variables (full-set model). We applied each model to three stratifications of data: patients with no history of HCV prior to 2020, patients with a history of HCV prior to 2020, and all patients. We used XGBoost and ten-fold C-statistic cross-validation to evaluate the generalizability of the models. There were 3564 unique patients, 487 with HCV infection. The average C-statistics on the structured-based, text-based, and full-set models for all the patients were 0.777 (95% CI: 0.744–0.810), 0.677 (95% CI: 0.631–0.723), and 0.774 (95% CI: 0.735–0.813), respectively. The full-set model performed slightly better than the structured-based model and similar to text-based models for patients with no history of HCV prior to 2020; average C-statistics of 0.780, 0.774, and 0.759, respectively. NLP was able to identify six more risk factors inconsistently coded in structured elements: incarceration, needlestick, substance use or abuse, sexually transmitted infections, piercings, and tattoos. The availability of model options (structured-based or text-based models) with a similar performance can provide deployment flexibility in situations where data is limited.","PeriodicalId":73131,"journal":{"name":"Gastrointestinal disorders (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45069313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How the Gut Microbiome Is Altered in COVID-19 新冠肺炎肠道微生物组的变化

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-03-20 DOI: 10.3390/gidisord5010011

G. Merra

引用次数: 0

Scoping Review of Acupuncture and Moxibustion in the Treatment of Inflammatory Bowel Disease 针灸治疗炎症性肠病的范围综述

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-03-03 DOI: 10.3390/gidisord5010010

A. Farrukh, J. Mayberry

引用次数: 0

Cognitive Impairment in Celiac Disease Patients: Scoping Review Exploring Psychological Triggers in a Chronic Condition 腹腔疾病患者的认知障碍：探讨慢性疾病心理触发因素的范围综述

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-03-01 DOI: 10.3390/gidisord5010009

Alberto Caruso, D. Di Giacomo

{"title":"Cognitive Impairment in Celiac Disease Patients: Scoping Review Exploring Psychological Triggers in a Chronic Condition","authors":"Alberto Caruso, D. Di Giacomo","doi":"10.3390/gidisord5010009","DOIUrl":"https://doi.org/10.3390/gidisord5010009","url":null,"abstract":"Celiac disease (CD), also known as gluten-sensitive enteropathy, is an inflammatory autoimmune reaction triggered by ingestion of gluten in genetically predisposed subjects. Celiac disease is often associated with a wide range of disorders, caused by immune responses and by malabsorption with subsequent nutritional deficiencies. Prevalent neurologic manifestations are ataxia, epilepsy, cerebral calcification, cerebral white matter lesions, peripheral neuropathy and myopathy, but also cognitive impairment. The study aimed to identify emerging and urgent research domains in order to establish a CD-specific patient-tailored protocol that includes both psychological and neuropsychological evaluations. We performed a systematic search of MEDLINE, PubMed, SCOPUS, Web of Science and Cochrane library in November 2022. We conducted a descriptive analysis of the characteristics of the included literature. Based on the exclusion/inclusion criteria, a total of seven articles were included in the scoping review process. This review demonstrated the lack of research on CD-related cognitive impairment key features and tries to focus on both cognitive and psychological manifestations as well as their two-way interaction. We tried to establish the specific areas involved, in order to have a comprehensive view of this condition and trying to determine a correct way of assessing CD cognitive impairment and its correlations with psychological distress and personal coping skills to a chronic condition. Nevertheless, research on this topic is progressively increasing and future studies should address specific key points.","PeriodicalId":73131,"journal":{"name":"Gastrointestinal disorders (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43801170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation and Management of Pediatric Feeding Disorder 小儿进食障碍的评估与治疗

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-02-16 DOI: 10.3390/gidisord5010008

Rajmohan Dharmaraj, Rasha A Elmaoued, Razan H. Alkhouri, P. Vohra, R. Castillo

引用次数: 4

Percutaneous Biliary Rendez-Vous to Treat Complete Hepatic-Jejunal Anastomosis Dehiscence after Duodeno-Cephalo-Pancreasectomy 经皮胆道融合治疗十二指肠-头-胰切除术后肝-空肠吻合完全破裂

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-02-06 DOI: 10.3390/gidisord5010007

F. Andresciani, G. Pacella, E. Faiella, Andrea Buoso, C. Altomare, R. Grasso

引用次数: 0

Gastrointestinal Involvement in Primary Antibody Deficiencies 一抗缺乏对胃肠道的影响

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-01-29 DOI: 10.3390/gidisord5010006

Tomáš Milota, J. Smetanova, I. Klojdová

{"title":"Gastrointestinal Involvement in Primary Antibody Deficiencies","authors":"Tomáš Milota, J. Smetanova, I. Klojdová","doi":"10.3390/gidisord5010006","DOIUrl":"https://doi.org/10.3390/gidisord5010006","url":null,"abstract":"Primary antibody deficiencies (PADs) are the most frequent group of inborn errors of immunity. Impaired B-cell development, reduced production of immunoglobulins (mainly IgG and IgA), and specific antibodies resulting in recurrent infections are their hallmarks. Infections typically affect the respiratory tract; however, gastrointestinal involvement is also common. These include infection with Helicobacter pylori, Salmonella, Campylobacter species, Giardia, and noroviruses. Impaired IgA production also contributes to dysbiosis and thereby an increase in abundance of species with proinflammatory properties, resulting in immune system dysregulation. Dysregulation of the immune system results in a broad spectrum of non-infectious manifestations, including autoimmune, lymphoproliferative, and granulomatous complications. Additionally, it increases the risk of malignancy, which may be present in more than half of patients with PADs. Higher prevalence is often seen in monogenic causes, and gastrointestinal involvement may clinically mimic various conditions including inflammatory bowel diseases and celiac disease but possess different immunological features and response to standard treatment, which make diagnosis and therapy challenging. The spectrum of malignancies includes gastric cancer and lymphoma. Thus, non-infectious manifestations significantly affect mortality and morbidity. In this overview, we provide a comprehensive insight into the epidemiology, genetic background, pathophysiology, and clinical manifestations of infectious and non-infectious complications.","PeriodicalId":73131,"journal":{"name":"Gastrointestinal disorders (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42145022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acknowledgment to the Reviewers of Gastrointestinal Disorders in 2022 感谢胃肠疾病审稿人在2022年

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-01-28 DOI: 10.3390/gidisord5010005

引用次数: 0

Heterogeneity in the Utilization of Fecal Occult Blood Testing and Colonoscopy among Migrants and Non-Migrants in Austria: Results of the Austrian Health Interview Survey 奥地利移民和非移民使用粪便隐血检查和结肠镜检查的异质性:奥地利健康访谈调查的结果

Gastrointestinal disorders (Basel, Switzerland) Pub Date : 2023-01-27 DOI: 10.3390/gidisord5010004

Diana Wahidie, Y. Yılmaz-Aslan, P. Brzoska

{"title":"Heterogeneity in the Utilization of Fecal Occult Blood Testing and Colonoscopy among Migrants and Non-Migrants in Austria: Results of the Austrian Health Interview Survey","authors":"Diana Wahidie, Y. Yılmaz-Aslan, P. Brzoska","doi":"10.3390/gidisord5010004","DOIUrl":"https://doi.org/10.3390/gidisord5010004","url":null,"abstract":"Many European studies report lower participation in colorectal cancer screening among migrants than non-migrants. A major limitation of these studies is that usually, the heterogeneity of migrants cannot be accounted for. The aim of this investigation was to examine differences in the utilization of fecal occult blood testing and colonoscopy between non-migrants and the five largest migrant groups residing in Austria using data from the Austrian Health Interview Survey 2019. The two outcomes were compared between non-migrants and migrants using multivariable logistic regression adjusted for socioeconomic and health variables. Migrants from a Yugoslav successor state (OR = 0.61; 95%-CI: 0.44–0.83), Turkish (OR = 0.35; 95%-CI: 0.22–0.55), Hungarian (OR = 0.37; 95%-CI: 0.16–0.82) and German migrants (OR = 0.70; 95%-CI: 0.51–0.98) were less likely to have used a fecal occult blood test compared to non-migrants. Participation in colonoscopy was lower among Turkish migrants (OR = 0.42; 95%-CI: 0.27–0.67) and migrants from a Yugoslav successor state (OR = 0.56; 95%-CI: 0.42–0.75) than among non-migrants. The findings are consistent with studies from other countries and highlight barriers migrants face in accessing the health care system. To address these barriers, the heterogeneity of the population must be taken into account when developing educational materials in order to promote informed decisions about whether or not to participate in colorectal cancer screening.","PeriodicalId":73131,"journal":{"name":"Gastrointestinal disorders (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43853814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0