Frontiers in photonics最新文献

筛选
英文 中文
Prospects for Fluorescence Molecular In Vivo Liquid Biopsy of Circulating Tumor Cells in Humans 人循环肿瘤细胞荧光分子活体液体活检的前景
Frontiers in photonics Pub Date : 2022-05-09 DOI: 10.3389/fphot.2022.910035
M. Niedre
{"title":"Prospects for Fluorescence Molecular In Vivo Liquid Biopsy of Circulating Tumor Cells in Humans","authors":"M. Niedre","doi":"10.3389/fphot.2022.910035","DOIUrl":"https://doi.org/10.3389/fphot.2022.910035","url":null,"abstract":"Our team recently developed “Diffuse in vivo Flow Cytometry” (DiFC) for detection and enumeration rare circulating tumor cells (CTCs) in mice with highly-scattered fluorescent light. We have used DiFC to study dissemination of CTCs in a number of mouse models of metastasis with fluorescent protein expressing cells. Because DiFC uses diffuse light and interrogates large blood vessels in relatively deep tissue, in principle it could be translated to larger limbs, species, and even humans clinically. In this perspective, we discuss the technical challenges of human translation of DiFC in the context of the current state of the technology, as well as potential strategies for labeling of CTCs with targeted fluorescent molecular probes. We also discuss potential advantages and disadvantages of DiFC as a clinical tool. In principle, DiFC could represent a powerful complementary technique (to liquid biopsy blood draws) for accurate and sensitive measurement of changes in CTC numbers over time.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43087201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Optical Simulation Study of Perovskite/CIGS Tandem Solar Cells With Reduced Graphene Oxide Layers 还原氧化石墨烯层钙钛矿/CIGS串联太阳能电池的光学模拟研究
Frontiers in photonics Pub Date : 2022-05-04 DOI: 10.3389/fphot.2022.888486
M. Kovačič, J. Krč, K. Savva, S. Maragkaki, E. Stratakis, Mudasar Rashid, Merve Tutundzic, Y. Kuang, J. de Wild, Tom Aernouts, B. Vermang, M. Topič
{"title":"Optical Simulation Study of Perovskite/CIGS Tandem Solar Cells With Reduced Graphene Oxide Layers","authors":"M. Kovačič, J. Krč, K. Savva, S. Maragkaki, E. Stratakis, Mudasar Rashid, Merve Tutundzic, Y. Kuang, J. de Wild, Tom Aernouts, B. Vermang, M. Topič","doi":"10.3389/fphot.2022.888486","DOIUrl":"https://doi.org/10.3389/fphot.2022.888486","url":null,"abstract":"Tandem solar cells present a promising solution to overcome the Schottky–Queisser efficiency limit of single-junction solar cells. In this article, an all–thin-film tandem solar cell based on perovskite (PK) top cell and chalcopyrite Cu (In, Ga) Se2 (CIGS) bottom cell is researched. Device optical simulations are validated on the top and bottom cells and employed for the analysis of PK/CIGS tandem cells. In particular, the optical effects of introduced laser reduced graphene oxide (rGO) layers at two positions in the tandem cell: 1) at the position between the top PK and bottom CIGS cell and 2) underneath the front transparent electrode. The purpose of introducing rGO layers is to improve the optoelectrical properties of the device, based on the tunable electronic and optical characteristics of rGO layers. Optical simulation results show that the parasitic absorption in rGO layers may noticeably affect the optical performance of the tandem cell if the layers are not optimized. The use of a thin and a few nanometer-thick rGO is suggested from the analysis if its parasitic absorption is not reduced. Directions for further optimization of optical rGO, including the reduction of parasitic absorption and tuning of the real part of the refractive index, are performed.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41595177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-Vivo Imaging of Ocular Microvasculature Using Swept-Source Optical Coherence Tomography Angiography in Seven Types of Lab Animals 用扫描源光学相干断层扫描对七种实验动物的眼部微血管系统进行体内成像
Frontiers in photonics Pub Date : 2022-04-26 DOI: 10.3389/fphot.2022.867594
Xuan Wu, Jacqueline Chua, C. Ho, X. Yao, A. R. Muralidharan, R. Najjar, G. Tan, E. Tamm, L. Schmetterer, V. Barathi, Bingyao Tan
{"title":"In-Vivo Imaging of Ocular Microvasculature Using Swept-Source Optical Coherence Tomography Angiography in Seven Types of Lab Animals","authors":"Xuan Wu, Jacqueline Chua, C. Ho, X. Yao, A. R. Muralidharan, R. Najjar, G. Tan, E. Tamm, L. Schmetterer, V. Barathi, Bingyao Tan","doi":"10.3389/fphot.2022.867594","DOIUrl":"https://doi.org/10.3389/fphot.2022.867594","url":null,"abstract":"The purpose of this study is to characterize the retinal and choroidal vascular networks in some of the most common animal species using swept-source optical coherence tomography angiography (SS-OCTA). Retinal angiographic images were acquired from healthy, anesthetized animals of seven species (mouse, rat, pig, rabbit, guinea pig, chicken, and non-human primate). We generated the enface angiograms to visualize the different retinal vascular plexuses and the choroidal vascular plexus. Quantitative OCTA metrics, including perfusion density, vessel density, and fractal dimension, were compared amongst the different species. There was a noticeable difference in the OCTA enface maps of the distinct vascular layers amongst the various species. Specifically, the non-human primate retina has the highest level of perfusion density and vessel density, whereas the rabbit retina exhibited the lowest level of vessel density. The mouse and the rat retina shared similar vascular patterns, and there was no difference in the OCTA metrics. Using one specific SS-OCTA system for all experiments eliminated multiple instrument-dependent factors, but the lateral resolution was still affected by eye size. Effects of varying lateral resolution on vascular metrics were investigated via a simulation. Overall, we achieved a large field of view of the distinct retinal and choroidal vascular plexuses and quantified the vascular metrics in multiple species, which could serve as protocol guidance and atlas to study the retinal and choroidal vascular abnormalities and their roles in ocular diseases resembling in-vivo histology.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44101273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transverse Traveling-Wave and Standing-Wave Ray-Wave Geometric Beams 横向行波和驻波射线波几何光束
Frontiers in photonics Pub Date : 2022-04-25 DOI: 10.3389/fphot.2022.855214
Zhaoyang Wang, Ruilin Long, Zhensong Wan, Zijian Shi, Xinjie Liu, Qiang Liu, X. Fu
{"title":"Transverse Traveling-Wave and Standing-Wave Ray-Wave Geometric Beams","authors":"Zhaoyang Wang, Ruilin Long, Zhensong Wan, Zijian Shi, Xinjie Liu, Qiang Liu, X. Fu","doi":"10.3389/fphot.2022.855214","DOIUrl":"https://doi.org/10.3389/fphot.2022.855214","url":null,"abstract":"Ray-wave geometric beam is an exotic kind of structured light with ray-wave duality and coupled diverse degrees of freedom (DoFs), which has attracted intense attention due to its potential applications in theories and applications. This work offers a new insight that the traditional ray-wave geometric beams can be seen as the transverse standing-wave (SW) beams, and can be decomposed into the superposition of transverse traveling-wave (TW) beams. We construct a generalized model for transverse TW and SW ray-wave geometric beams in the wave picture. In experiment, we exploit a digital hologram system with more flexible tunable DoFs to generate the transverse TW and SW beams, inspiring the exploration for the spatial wave structure of more complex structured light.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46191283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Survey for 3D Flame Chemiluminescence Tomography: Theory, Algorithms, and Applications (Invited) 三维火焰化学发光层析成像:理论、算法和应用(特邀)
Frontiers in photonics Pub Date : 2022-03-29 DOI: 10.3389/fphot.2022.845971
Ying Jin, G. Situ
{"title":"A Survey for 3D Flame Chemiluminescence Tomography: Theory, Algorithms, and Applications (Invited)","authors":"Ying Jin, G. Situ","doi":"10.3389/fphot.2022.845971","DOIUrl":"https://doi.org/10.3389/fphot.2022.845971","url":null,"abstract":"Combustion diagnostics play an essential role in energy engineering, transportation, and aerospace industries, which has great potential in combustion efficiency improvement and polluting emission control. The three-dimensional (3D) visualization of the combustion field and the measurement of key physical parameters such as temperature, species concentration, and velocity during the combustion process are important topics in the field of combustion diagnostics. Benefiting from the non-contact and non-intrusive advantages of the optical detection method as well as the advantages of the 3D full-field measurement of the measured field by computational tomography, flame chemiluminescence tomography (FCT) has the ability to realize non-intrusive and instantaneous 3D quantitative measurement and 3D full-field visualization of key physical parameters in the combustion process, which has crucial research significance in combustion diagnostics. In this study, we review the progress of FCT technique. First, we provide an extensive review of practical applications of FCT in state-of-the-art combustion diagnostics and research. Then, the basic concepts and mathematical theory of FCT are elaborated. Finally, we introduce the conventional reconstruction algorithm and proceed to more popular artificial intelligence-based algorithms.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45872838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Fringe Printer With 0.35 μm Pixel Pitch 0.35 μm像素间距条纹打印机的研制
Frontiers in photonics Pub Date : 2022-03-28 DOI: 10.3389/fphot.2022.843860
Takeshi Yamaguchi, H. Yoshikawa
{"title":"Development of a Fringe Printer With 0.35 μm Pixel Pitch","authors":"Takeshi Yamaguchi, H. Yoshikawa","doi":"10.3389/fphot.2022.843860","DOIUrl":"https://doi.org/10.3389/fphot.2022.843860","url":null,"abstract":"The development of computational devices can provide computer-generated holograms (CGH) of over 100 Giga-pixel easily. The performance improvement of the graphical processing unit makes calculations faster with a normal personal computer. In contrast, the output device of CGH is not reported much. Since CGH is a fringe pattern, high resolution and fine pixel pitch are required for the output device. We have been developing a direct fringe printer, which consists of a laser, an X-Y stage, an SLM, and optical parts available on the market. Our previous report presented a liquid crystal panel, which was used for SLM that had full HD resolution and 7 μm pixel pitch. Since the Pixel pitch of the liquid crystal panel is not small enough for CGH, the optical setup works to demagnify the pixel pitch of the printed fringe pattern. To record high resolution CGH, the calculated fringe pattern is split and exposed in tiles by the X–Y stage. The results showed a 0.44 μm pixel pitch and over 100 Gpixel CGHs. However, to output more high-quality CGH, the development of pixel pitch and resolution is very important. In this paper, we review the optical system of a fringe printer that achieved an output of 0.35 μm pixel pitch CGH. We also investigate the performance of the new fringe printer.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46626290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep-Learning Computational Holography: A Review (Invited) 深度学习计算全息:综述(特邀)
Frontiers in photonics Pub Date : 2022-03-28 DOI: 10.3389/fphot.2022.854391
T. Shimobaba, David Blinder, Tobias Birnbaum, I. Hoshi, Harutaka Shiomi, P. Schelkens, T. Ito
{"title":"Deep-Learning Computational Holography: A Review (Invited)","authors":"T. Shimobaba, David Blinder, Tobias Birnbaum, I. Hoshi, Harutaka Shiomi, P. Schelkens, T. Ito","doi":"10.3389/fphot.2022.854391","DOIUrl":"https://doi.org/10.3389/fphot.2022.854391","url":null,"abstract":"Deep learning has been developing rapidly, and many holographic applications have been investigated using deep learning. They have shown that deep learning can outperform previous physically-based calculations using lightwave simulation and signal processing. This review focuses on computational holography, including computer-generated holograms, holographic displays, and digital holography, using deep learning. We also discuss our personal views on the promise, limitations and future potential of deep learning in computational holography.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42595874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
A Multi-Wavelength Phase Retrieval With Multi-Strategy for Lensfree On-Chip Holography 基于多策略的无透镜片上全息多波长相位恢复
Frontiers in photonics Pub Date : 2022-03-28 DOI: 10.3389/fphot.2022.865666
Qinhua Wang, Jianshe Ma, Ping Su
{"title":"A Multi-Wavelength Phase Retrieval With Multi-Strategy for Lensfree On-Chip Holography","authors":"Qinhua Wang, Jianshe Ma, Ping Su","doi":"10.3389/fphot.2022.865666","DOIUrl":"https://doi.org/10.3389/fphot.2022.865666","url":null,"abstract":"Due to convenient operation and robust imaging, multi-wavelength phase retrieval has been widely applied in lensfree on-chip digital holographic microscope (LFOCDHM). Nevertheless, the insufficient diffraction variation and small number of measurements on the LFOCDHM make it difficult to eliminate the twin image by multi-wavelength phase retrieval. We propose a multi-wavelength phase retrieval for LFOCDHM based on energy constraint, global update strategy, and vector extrapolation acceleration. Simulations and experiments on the LFOCDHM show that our proposed method realizes efficient elimination effect and robust reconstruction with three wavelengths for illumination while maintaining fast convergence. More importantly, the proposed method is simple and non-parametric. It is believed that the proposed method could provide a promising solution for LFOCDHM.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41957953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Frontiers in Photonics Spot Light 光子学前沿聚光灯
Frontiers in photonics Pub Date : 2022-03-09 DOI: 10.3389/fphot.2022.853456
Bahman Anvari, C. de Angelis, Shujuan Huang, N. Litchinitser, T. Poon, G. Scalari, B. Richards, M. Peccianti
{"title":"Frontiers in Photonics Spot Light","authors":"Bahman Anvari, C. de Angelis, Shujuan Huang, N. Litchinitser, T. Poon, G. Scalari, B. Richards, M. Peccianti","doi":"10.3389/fphot.2022.853456","DOIUrl":"https://doi.org/10.3389/fphot.2022.853456","url":null,"abstract":"Recognizing remarkable achievements and innovations is an important mission in scientific dissemination. The editors of Frontiers in Photonics would like to acknowledge and give visibility to some of the best recent research outputs and to their authors in this spot-light review.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46179639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compressive Interferenceless Coded Aperture Correlation Holography With High Imaging Quality (Invited) 高成像质量压缩无干涉编码孔径相关全息术(受邀)
Frontiers in photonics Pub Date : 2022-03-04 DOI: 10.3389/fphot.2022.846731
Chao Liu, Tianlong Man, Yuhong Wan
{"title":"Compressive Interferenceless Coded Aperture Correlation Holography With High Imaging Quality (Invited)","authors":"Chao Liu, Tianlong Man, Yuhong Wan","doi":"10.3389/fphot.2022.846731","DOIUrl":"https://doi.org/10.3389/fphot.2022.846731","url":null,"abstract":"Interferenceless coded aperture correlation holography (I-COACH) provides an alternative way for the 3D imaging of spatial incoherent illuminated or fluorescent sample. However, the low imaging signal-to-noise ratio (SNR) is one of the bottlenecks that restrict the application of I-COACH. The limitation is mainly originated from the strong bias level that presents in the recorded holograms. Phase shifting methods were implemented in I-COACH to eliminate the background noise while the multiple-exposures recording mechanism significantly reduces the temporal resolution of the system. In this paper, we proposed a compressive I-COACH imaging method with high reconstruction quality and without the sacrifice of the imaging speed. The 3D holographic image reconstruction was implemented under compressive sensing framework while only one single-exposure object hologram and one point spread hologram are necessary. High quality reconstructions were obtained using the proposed method, even for the down-sampled holograms. The imaging SNR of the I-COACH system was improved by a factor of more than 16.5% when comparing with the imaging SNR obtained by the conventional cross-correlation reconstruction method. The proposed method provides a fast and high-fidelity imaging method that can potentially benefit the imaging through scattering medium, partial aperture imaging, and other fields.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41399541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信