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Artificial light at night alters progression of cold neuropathy in a sex-dependent manner in a mouse model of type II diabetes mellitus 夜间人造光以性别依赖的方式改变 II 型糖尿病小鼠模型中冷神经病变的进程
Frontiers in photonics Pub Date : 2024-02-06 DOI: 10.3389/fphot.2024.1323539
Jacob R. Bumgarner, Rhett C. White, Jordan A. Brown, Randy J. Nelson
{"title":"Artificial light at night alters progression of cold neuropathy in a sex-dependent manner in a mouse model of type II diabetes mellitus","authors":"Jacob R. Bumgarner, Rhett C. White, Jordan A. Brown, Randy J. Nelson","doi":"10.3389/fphot.2024.1323539","DOIUrl":"https://doi.org/10.3389/fphot.2024.1323539","url":null,"abstract":"Artificial light at night (ALAN) is a pervasive circadian rhythm disruptor. Exposure to ALAN is associated with detrimental effects on physiology and behavior, including disrupted metabolism, immune function, endocrine function, and pain behavior. Given the detrimental effects of ALAN and other circadian rhythm disruptors on pain, we sought to understand how ALAN may alter the progression and severity of diabetic neuropathy. To do this, we used a previously reported high-fat diet and streptozotocin injection protocol to induce a type II diabetic phenotype in ∼8 week old female and male mice and then exposed the mice to either control or ALAN lighting conditions in 14:10 h light-dark cycles for 4 weeks. Male mice housed in control conditions exhibited reduced responsiveness to cold pain; in contrast, ALAN blunted this effect in male mice. ALAN exposure also elevated blood glucose and altered body mass loss in male mice. These effects were not present in female mice. The results of this study highlight the need to consider and study ALAN exposure and sex as a biological variable as risk factors in the treatment and mitigation of pain.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139801835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in microemulsion-based fabrication of upconversion-mediated multifunctional materials 基于微乳液制备上转换介导多功能材料的进展
Frontiers in photonics Pub Date : 2024-02-02 DOI: 10.3389/fphot.2024.1363223
Yi Zhang, Qingsong Mei, Zhen Zhang
{"title":"Advancements in microemulsion-based fabrication of upconversion-mediated multifunctional materials","authors":"Yi Zhang, Qingsong Mei, Zhen Zhang","doi":"10.3389/fphot.2024.1363223","DOIUrl":"https://doi.org/10.3389/fphot.2024.1363223","url":null,"abstract":"Upconversion nanoparticles (UCNPs) have experienced significant advancements, finding applications in diverse fields over the past decade. The growing demand for UCNP-based nanoplatforms with multifunctionality to address complex scenarios has led to the emergence of the microemulsion confined self-assembly method, which allows for the integration of different UCNPs or UCNPs with additional functional materials within a single entity, resulting in a nanoplatform that possesses a wide range of properties suitable for specific applications. This comprehensive review aimed to summarize recent developments in the design of UCNP assemblies using the microemulsion confined self-assembly method, which focused on exploring their applications in critical areas such as color encoding, bioimaging, and programmable therapeutics. Furthermore, the review acknowledged the existing limitations associated with the microemulsion confined self-assembly method and provided an in-depth discussion of potential solutions to overcome these challenges, aiming to foster further progress and innovation in the design and application of UCNP assemblies.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139811590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in microemulsion-based fabrication of upconversion-mediated multifunctional materials 基于微乳液制备上转换介导多功能材料的进展
Frontiers in photonics Pub Date : 2024-02-02 DOI: 10.3389/fphot.2024.1363223
Yi Zhang, Qingsong Mei, Zhen Zhang
{"title":"Advancements in microemulsion-based fabrication of upconversion-mediated multifunctional materials","authors":"Yi Zhang, Qingsong Mei, Zhen Zhang","doi":"10.3389/fphot.2024.1363223","DOIUrl":"https://doi.org/10.3389/fphot.2024.1363223","url":null,"abstract":"Upconversion nanoparticles (UCNPs) have experienced significant advancements, finding applications in diverse fields over the past decade. The growing demand for UCNP-based nanoplatforms with multifunctionality to address complex scenarios has led to the emergence of the microemulsion confined self-assembly method, which allows for the integration of different UCNPs or UCNPs with additional functional materials within a single entity, resulting in a nanoplatform that possesses a wide range of properties suitable for specific applications. This comprehensive review aimed to summarize recent developments in the design of UCNP assemblies using the microemulsion confined self-assembly method, which focused on exploring their applications in critical areas such as color encoding, bioimaging, and programmable therapeutics. Furthermore, the review acknowledged the existing limitations associated with the microemulsion confined self-assembly method and provided an in-depth discussion of potential solutions to overcome these challenges, aiming to foster further progress and innovation in the design and application of UCNP assemblies.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139871175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Grand challenges in neuromorphic photonics and photonic computing 神经形态光子学和光子计算的重大挑战
Frontiers in photonics Pub Date : 2024-01-29 DOI: 10.3389/fphot.2023.1336510
Francesco Morichetti
{"title":"Grand challenges in neuromorphic photonics and photonic computing","authors":"Francesco Morichetti","doi":"10.3389/fphot.2023.1336510","DOIUrl":"https://doi.org/10.3389/fphot.2023.1336510","url":null,"abstract":"","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140486770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of defect mitigation strategies for UMG-Si wafers UMG-Si 晶圆缺陷缓解策略综述
Frontiers in photonics Pub Date : 2024-01-10 DOI: 10.3389/fphot.2023.1331471
Rabin Basnet, Daniel Macdonald
{"title":"A review of defect mitigation strategies for UMG-Si wafers","authors":"Rabin Basnet, Daniel Macdonald","doi":"10.3389/fphot.2023.1331471","DOIUrl":"https://doi.org/10.3389/fphot.2023.1331471","url":null,"abstract":"This review focuses on the challenges and potential pathways for utilizing upgraded metallurgical-grade silicon (UMG-Si) in the silicon photovoltaic industry. UMG-Si is an attractive low-cost alternative silicon feedstock, but its bulk quality is compromised due to the presence of defects and impurities. The review begins by identifying and discussing the various defects and impurities commonly found in UMG-Si wafers, drawing insights from a literature survey. The detrimental effects of these defects on solar cell performance are highlighted. Next, the review provides a summary of defect mitigation strategies that have been employed to improve the bulk quality of UMG-Si wafers. These strategies include tabula rasa, impurity gettering, and defect/impurity passivation through hydrogenation. The effectiveness of these strategies is evaluated by considering carrier lifetimes and comparing them with those of conventional silicon wafers. The review then examines the reported open-circuit voltages and efficiencies of solar cells based on UMG-Si wafers. A comparison is made between the performance of UMG-Si solar cells and those fabricated on conventional silicon. The impact of defect mitigation strategies on the performance of UMG-Si solar cells is discussed, emphasizing the improvements achieved through these strategies.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139439234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid quantification in living microalgal cultures with digital holographic microscopy 利用数字全息显微镜量化活体微藻培养物中的脂质
Frontiers in photonics Pub Date : 2024-01-05 DOI: 10.3389/fphot.2023.1301708
C. Yourassowsky, Renaud Theunissen, Jérôme Dohet-Eraly, Frank Dubois
{"title":"Lipid quantification in living microalgal cultures with digital holographic microscopy","authors":"C. Yourassowsky, Renaud Theunissen, Jérôme Dohet-Eraly, Frank Dubois","doi":"10.3389/fphot.2023.1301708","DOIUrl":"https://doi.org/10.3389/fphot.2023.1301708","url":null,"abstract":"Large amounts of lipids are stored inside lipid droplets by some microalgae. Since these lipids can be used to produce nutraceuticals and biodiesel in a sustainable way, research is developing on fast non-destructive methods to quantify and monitor the amount of lipids within microalgal cultures. In this paper, we have developed with digital holographic microscopy a fast quantitative method to assess the evolution of the lipid content inside the diatom Phaeodactylum tricornutum living cells. The method uses a specific processing of recorded hologram sequences based on the refocusing capability in digital holographic microscopy. In representative samples of the culture, inside living cells, each lipid droplet volume is evaluated. In those experiments, for each sample, more than one thousand lipid droplets are automatically analysed from a sequence of one hundred recorded holograms. We have validated the method thanks to correlative quantitative phase contrast–fluorescence imaging and extrapolated it to larger calibrated spherical refractive particles, to demonstrate the flexibility of the method.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139381048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorescence imaging for the anterior segment of the eye 眼球前段荧光成像技术
Frontiers in photonics Pub Date : 2024-01-03 DOI: 10.3389/fphot.2023.1336541
Joshua M. Herzog, Volker Sick
{"title":"Fluorescence imaging for the anterior segment of the eye","authors":"Joshua M. Herzog, Volker Sick","doi":"10.3389/fphot.2023.1336541","DOIUrl":"https://doi.org/10.3389/fphot.2023.1336541","url":null,"abstract":"Diagnostic technologies for the anterior segment of the eye, especially for hard-to-diagnose diseases such as microbial keratitis, are still lacking. Although in vivo confocal microscopy and optical coherence tomography are becoming more widely applicable to a variety of conditions, they are often prohibitively expensive, require specialized training and equipment, and are intrinsically insensitive to chemical changes. Here, ultraviolet-fluorescence imaging is proposed as a new technique to aid in investigation of the anterior segment. In this work, a novel two-color line-of-sight fluorescence imaging technique is described for imaging of the anterior segment. The technique is applied to seven ex vivo porcine eyes to illustrate the utility of the technique. The image data was used to estimate an effective fluorescence quantum yield of each eye at 370 nm. The eyes were then inoculated with bacteria to simulate microbial keratitis, a common sight-threatening infection, and the measurement was repeated. A simplified fluorescence-extinction model was developed to describe and analyze the relative intensities of the eye and biofilm fluorescence. Overall, the technique appears to have utility in clinical practice and with proper development may be suitable for detecting chemical changes in the eye, or the presence of foreign matter; however, further investigation is needed to develop the technique and analysis procedures into a quantitative diagnostic tool.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139387680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficient and robust second-harmonic generation in thin-film lithium niobate using modal phase matching 利用模态相位匹配在薄膜铌酸锂中产生高效稳健的二次谐波
Frontiers in photonics Pub Date : 2023-11-24 DOI: 10.3389/fphot.2023.1324648
M. T. Hansen, E. Ulsig, Fabien Labbe, Magnus L. Madsen, Yunhong Ding, Karsten Rottwitt, N. Volet
{"title":"Efficient and robust second-harmonic generation in thin-film lithium niobate using modal phase matching","authors":"M. T. Hansen, E. Ulsig, Fabien Labbe, Magnus L. Madsen, Yunhong Ding, Karsten Rottwitt, N. Volet","doi":"10.3389/fphot.2023.1324648","DOIUrl":"https://doi.org/10.3389/fphot.2023.1324648","url":null,"abstract":"A double-ridge waveguide is designed for efficient and robust second-harmonic generation (SHG) using the thin-film lithium-niobate-on-insulator (LNOI) platform. Perfect phase matching (PhM) is achieved between the fundamental waveguide mode at 1,550 nm and a higher-order mode at the second harmonic. The fabrication tolerances of the PhM condition are simulated using a finite-difference method mode solver, and conversion efficiencies as high as 3.92 W−1 are obtained for a 1-cm long waveguide. This design allows access to the largest element of the second-order nonlinear susceptibility tensor, and represents a scalable alternative to waveguides based on periodically-poled lithium niobate (PPLN). The design has the potential for generating pairs of entangled photons in the infrared C-band by spontaneous parametric down-conversion (SPDC).","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139241743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lights should support circadian rhythms: evidence-based scientific consensus 灯光应该支持昼夜节律:基于证据的科学共识
Frontiers in photonics Pub Date : 2023-10-04 DOI: 10.3389/fphot.2023.1272934
Martin Moore-Ede, David E. Blask, Sean W. Cain, Anneke Heitmann, Randy J. Nelson
{"title":"Lights should support circadian rhythms: evidence-based scientific consensus","authors":"Martin Moore-Ede, David E. Blask, Sean W. Cain, Anneke Heitmann, Randy J. Nelson","doi":"10.3389/fphot.2023.1272934","DOIUrl":"https://doi.org/10.3389/fphot.2023.1272934","url":null,"abstract":"For over a hundred years, the lighting industry has primarily been driven by illumination aesthetics, energy efficiency and product cost with little consideration of the effects of light on health. The recent widespread replacement of traditional light sources by blue-enriched LED lights has heightened concerns about the disruption of the blue-sensitive human circadian system by these LED lights and their impact on the multiple health disorders linked to circadian disruption. Despite these health concerns, less than 0.5% of the lighting sold today modifies spectral content and intensity between day and night. We report that 248 scientists, with a total of 2,697 peer-reviewed publications on light and circadian clocks since 2008, reached consensus on 25 statements about the impact of light on circadian rhythms and health based on accumulated scientific evidence, including support for the widespread introduction of circadian lighting and warning labels on blue-enriched LED lights indicating they “maybe harmful if used at night”.","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135590551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Editorial: Advances in plasmonics: a European collection 社论：等离子体的进展：欧洲收藏
Frontiers in photonics Pub Date : 2023-08-24 DOI: 10.3389/fphot.2023.1270553
Michele Ortolani, C. Ciracì, M. Giordano, S. D’Agostino
{"title":"Editorial: Advances in plasmonics: a European collection","authors":"Michele Ortolani, C. Ciracì, M. Giordano, S. D’Agostino","doi":"10.3389/fphot.2023.1270553","DOIUrl":"https://doi.org/10.3389/fphot.2023.1270553","url":null,"abstract":"","PeriodicalId":73099,"journal":{"name":"Frontiers in photonics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42062605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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