Frontiers in clinical diabetes and healthcare最新文献

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Charcot neuro-osteoarthropathy: a review of key concepts and an evidence-based surgical management algorithm. Charcot 神经骨关节病:关键概念综述和循证外科治疗算法。
Frontiers in clinical diabetes and healthcare Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.3389/fcdhc.2024.1344359
Miltiadis Argyropoulos, William Wynell-Mayow, Oscar Johnson, Radwane Faroug, Karanjeev Singh Johal, Rupinderbir Singh Deol, Atef Hakmi, Simon Mordecai
{"title":"Charcot neuro-osteoarthropathy: a review of key concepts and an evidence-based surgical management algorithm.","authors":"Miltiadis Argyropoulos, William Wynell-Mayow, Oscar Johnson, Radwane Faroug, Karanjeev Singh Johal, Rupinderbir Singh Deol, Atef Hakmi, Simon Mordecai","doi":"10.3389/fcdhc.2024.1344359","DOIUrl":"10.3389/fcdhc.2024.1344359","url":null,"abstract":"<p><p>Charcot neuro-osteoarthropathy (CNO), mainly as a result of diabetic neuropathy, is a complex problem which carries significant morbidity, and is an increasing burden on healthcare as demographics change globally. A multi-disciplinary team (MDT) is necessary to treat the multiple facets of this disease. The multifactorial and non-homogenous nature of this condition and its management, has prevented the development of comprehensive guidelines based on level 1 evidence. Although there is a trend to surgically treat these patients in tertiary centres, the increasing prevalence of CNO necessitates the capability of all units to manage this condition to an extent locally. This article conducted a thorough literature search of Pubmed and Embase from 2003 to 2023 including the following search terms; \"Charcot\" \"neuroarthropathy\" \"diabetic foot\" \"management\" \"surgery\" \"treatment\" \"reconstruction\". The results of this review have been summarised and synthesised into an evidence-based algorithm to aid in the surgical decision-making process, and improve the understanding of surgical management by the whole MDT.</p>","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review of diabetic foot infections: pathogenesis, diagnosis, and management strategies. 糖尿病足感染的系统回顾:发病机制、诊断和管理策略。
Frontiers in clinical diabetes and healthcare Pub Date : 2024-08-06 eCollection Date: 2024-01-01 DOI: 10.3389/fcdhc.2024.1393309
Sabyasachi Maity, Noah Leton, Narendra Nayak, Ameet Jha, Nikhilesh Anand, Kamala Thompson, Danielle Boothe, Alexandra Cromer, Yaliana Garcia, Aliyah Al-Islam, Samal Nauhria
{"title":"A systematic review of diabetic foot infections: pathogenesis, diagnosis, and management strategies.","authors":"Sabyasachi Maity, Noah Leton, Narendra Nayak, Ameet Jha, Nikhilesh Anand, Kamala Thompson, Danielle Boothe, Alexandra Cromer, Yaliana Garcia, Aliyah Al-Islam, Samal Nauhria","doi":"10.3389/fcdhc.2024.1393309","DOIUrl":"10.3389/fcdhc.2024.1393309","url":null,"abstract":"<p><strong>Background: </strong>Diabetic foot infection represents a significant complication of diabetes mellitus, contributing substantially to morbidity, mortality, and healthcare expenditure worldwide. Accurate diagnosis relies on a comprehensive assessment integrating clinical evaluation, imaging studies, and microbiological analysis. Management necessitates a multidisciplinary approach, encompassing surgical intervention, antimicrobial therapy, and advanced wound care strategies. Preventive measures are paramount in reducing the incidence and severity, emphasizing patient education, regular foot screenings, and early intervention.</p><p><strong>Methods: </strong>The researchers performed a systematic review of literature using PUBMED MESH keywords. Additionally, the study was registered in the International Prospective Register of Systematic Reviews at the Center for Reviews and Dissemination, University of York (CRD42021277788). This review provides a comprehensive overview of the microbial spectrum and antibiotic susceptibility patterns observed in diabetic foot infections.</p><p><strong>Results: </strong>The search through the databases finally identified 13 articles with 2545 patients from 2021 to 2023. Overall, the predominant Gram-positive microbial species isolated were Staphylococcus aureus, Enterococcus fecalis, Streptococcus pyogenes, Streptococcus agalactiae, and Staphylococcus epidermidis. Whereas the predominant Gram-negative included Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa.</p><p><strong>Conclusion: </strong>Diabetic foot infections represent a complex and multifaceted clinical entity, necessitating a holistic approach to diagnosis, management, and prevention. Limited high-quality research data on outcomes and the effectiveness of guideline recommendations pose challenges in updating and refining existing DFI management guidelines.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021277788, identifier CRD42021277788.</p>","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11333436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of diabetes self-management programs on clinical and patient reported outcomes in older adults: a systematic review and meta-analysis. 糖尿病自我管理计划对老年人临床和患者报告结果的影响:系统回顾和荟萃分析。
Frontiers in clinical diabetes and healthcare Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.3389/fcdhc.2024.1348104
Paige Alliston, Milos Jovkovic, Saira Khalid, Donna Fitzpatrick-Lewis, Muhammad Usman Ali, Diana Sherifali
{"title":"The effects of diabetes self-management programs on clinical and patient reported outcomes in older adults: a systematic review and meta-analysis.","authors":"Paige Alliston, Milos Jovkovic, Saira Khalid, Donna Fitzpatrick-Lewis, Muhammad Usman Ali, Diana Sherifali","doi":"10.3389/fcdhc.2024.1348104","DOIUrl":"10.3389/fcdhc.2024.1348104","url":null,"abstract":"<p><strong>Objectives: </strong>With diabetes self-management continuing to become more complex for older adults, self-management programs have been shown to support this population in meeting their multifaceted medical needs. Building on our previous systematic review and meta-analysis, we aimed to update the literature on the effectiveness of diabetes self-management programs and investigate the impact of specific self-management interventions on clinical and patient-reported outcomes.</p><p><strong>Methods: </strong>We updated our literature search in the following databases: Medline, EMBASE, PsychINFO, CINAHL and Cochrane Database of Randomized Controlled Trials from November 2013 to July 2023 for studies that may fit our inclusion criteria. Two independent reviewers screened and extracted data from the included group of studies.</p><p><strong>Results: </strong>A total of 17 studies with 21 comparison arms met the inclusion criteria, totalling 5976 older adults (3510 individuals randomized to self-management programming and 2466 to usual care). The pooled effectiveness of diabetes self-management programs in older adults on glycemic control (hemoglobin A1C) was a reduction of -0.32 (95% CI -0.44, -0.19). Specifically, the most effective approach on glycemic control (A1C) was the use of feedback (-0.52%; 95% CI -0.68, -0.36). Overall, self-management programs improved behaviour change outcomes, with feedback interventions being most effective (standardized mean difference [SMD] 0.91; 95% CI 0.39, 1.43). The effect of self-management programs on body mass index, weight and lipids were statistically and clinically significant.</p><p><strong>Conclusions: </strong>The evidence for diabetes self-management programs for older adults demonstrates a small but clinically meaningful reduction in A1C, improvement in patient-reported outcomes (behaviour, self-efficacy, knowledge), and other clinical outcomes (BMI, weight and lipids). The specific strategy used in diabetes self-management programs for older adults should be considered to achieve optimal results on outcomes.</p>","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11215190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141478125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supporting healthy lifestyles for First Nations women and communities through co-design: lessons and early findings from remote Northern Australia. 通过共同设计支持原住民妇女和社区的健康生活方式:澳大利亚北部偏远地区的经验教训和早期发现。
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-28 eCollection Date: 2024-01-01 DOI: 10.3389/fcdhc.2024.1356060
Tara Dias, Diana MacKay, Karla Canuto, Jacqueline A Boyle, Heather D'Antoine, Denella Hampton, Kim Martin, Jessica Phillips, Norlisha Bartlett, H David Mcintyre, Sian Graham, Sumaria Corpus, Christine Connors, Leisa McCarthy, Renae Kirkham, Louise J Maple-Brown
{"title":"Supporting healthy lifestyles for First Nations women and communities through co-design: lessons and early findings from remote Northern Australia.","authors":"Tara Dias, Diana MacKay, Karla Canuto, Jacqueline A Boyle, Heather D'Antoine, Denella Hampton, Kim Martin, Jessica Phillips, Norlisha Bartlett, H David Mcintyre, Sian Graham, Sumaria Corpus, Christine Connors, Leisa McCarthy, Renae Kirkham, Louise J Maple-Brown","doi":"10.3389/fcdhc.2024.1356060","DOIUrl":"10.3389/fcdhc.2024.1356060","url":null,"abstract":"<p><strong>Background: </strong>The period before, during, and after pregnancy presents an opportunity to reduce diabetes-related risks, which in Australia disproportionately impact Aboriginal and Torres Strait Islander women. Collaboration with Aboriginal and Torres Strait Islander women/communities is essential to ensure acceptability and sustainability of lifestyle modifications. Using a novel co-design approach, we aimed to identify shared priorities and potential lifestyle strategies. We also reflected on learnings from this approach.</p><p><strong>Methods: </strong>We conducted 11 workshops and 8 interviews at two sites in Australia's Northern Territory (Central Australia and Top End), using experience-based co-design (EBCD) and incorporating principles of First Nations participatory research. Workshops/interviews explored participant' experiences and understanding of diabetes in pregnancy, contextual issues, and potential lifestyle strategies. Participants included three groups: 1) Aboriginal and Torres Strait Islander women of reproductive age (defined as aged 16-45 years); 2) Aboriginal and Torres Strait Islander community members; and 3) health/community services professionals. The study methodology sought to amplify the voices of Aboriginal women.</p><p><strong>Findings: </strong>Participants included 23 women between ages 16-45 years (9 with known lived experience of diabetes in pregnancy), 5 community members and 23 health professionals. Key findings related to identified priority issues, strategies to address priorities, and reflections on use of EBCD methodology. Priorities were largely consistent across study regions: access to healthy foods and physical activity; connection to traditional practices and culture; communication regarding diabetes and related risks; and the difficulty for women of prioritising their health among competing priorities. Strategies included implementation of a holistic women's program in Central Australia, while Top End participants expressed the desire to improve nutrition, peer support and community awareness of diabetes. EBCD provided a useful structure to explore participants' experiences and collectively determine priorities, while allowing for modifications to ensure co-design methods were contextually appropriate. Challenges included the resource-intensive nature of stakeholder engagement, and collaborating effectively with services and communities when researchers were \"outsiders\".</p><p><strong>Conclusions: </strong>A hybrid methodology using EBCD and First Nations participatory research principles enabled collaboration between Aboriginal women, communities and health services to identify shared priorities and solutions to reduce diabetes-related health risks. Genuine co-design processes support self-determination and enhance acceptability and sustainability of health strategies.</p>","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic syndrome and pharmacotherapy outcomes in patients with type 2 diabetes mellitus 2 型糖尿病患者的代谢综合征与药物治疗效果
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-23 DOI: 10.3389/fcdhc.2024.1380244
Shawqi H Alawdi, Mohammed Al-Dholae, Salah Al-Shawky
{"title":"Metabolic syndrome and pharmacotherapy outcomes in patients with type 2 diabetes mellitus","authors":"Shawqi H Alawdi, Mohammed Al-Dholae, Salah Al-Shawky","doi":"10.3389/fcdhc.2024.1380244","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1380244","url":null,"abstract":"Metabolic syndrome is a group of metabolic abnormalities that increase predisposition to several diseases including ischemic heart disease and diabetes mellitus. The study aimed to investigate metabolic syndrome among patients with type-2 diabetes mellitus (DM), and its impact on pharmacotherapy outcomes.An observational cross-sectional study was performed on 910 patients with type-2 DM between June and December 2023. Fasting blood sugar, triglycerides, high-density lipoproteins (HDL), blood pressure, and abdominal obesity were measured. Metabolic syndrome was identified according to the National Cholesterol Education Program Adult Treatment Panel III criteria. Pharmacotherapy outcomes were assessed according to American Association of Clinical Endocrinologists and American Diabetes Association guidelines using the ability to achieve adequate glycemic control and normal levels of blood pressure and fasting plasma lipoproteins.In total, 87.5% of type-2 DM patients had metabolic syndrome; the prevalence increased with age and was higher among females. Metabolic syndrome showed the following distribution of risk factors: insulin resistance (100%), low HDL (95.3%), elevated blood pressure (83%), triglycerides dyslipidemia (80.1%), and abdominal obesity (62.5%). Majority of the patients had either 5 or 4 risk factors of metabolic syndrome. The most common comorbidities were dyslipidemia (97.7%) and hypertension (83%). Treatment outcomes were insufficient where adequate glycemic control was only achieved in 12% of type-2 DM patients, and proper management of comorbid dyslipidemia and hypertension was achieved in 29% and 40.9% of patients, respectively. Adequate blood pressure control was less achieved in patients with metabolic syndrome (34.4%) than those without metabolic syndrome (77.2%). Similarly, dyslipidemia was less controlled in patients with metabolic syndrome (26.9%) than in those without metabolic syndrome (47.3%).Pharmacotherapy outcomes were inadequate for most patients with type-2 diabetes mellitus. Adopting early preventive and therapeutic interventions for metabolic syndrome is advised to improve treatment outcomes of the comorbid dyslipidemia and hypertension.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141107459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acceptability of community health worker and peer supported interventions for ethnic minorities with type 2 diabetes: a qualitative systematic review 针对 2 型糖尿病少数民族患者的社区保健员和同伴支持干预措施的可接受性:定性系统综述
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-21 DOI: 10.3389/fcdhc.2024.1306199
Vivene Grant, Ian Litchfield
{"title":"Acceptability of community health worker and peer supported interventions for ethnic minorities with type 2 diabetes: a qualitative systematic review","authors":"Vivene Grant, Ian Litchfield","doi":"10.3389/fcdhc.2024.1306199","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1306199","url":null,"abstract":"Ethnic minority groups in high income countries in North America, Europe, and elsewhere are disproportionately affected by T2DM with a higher risk of mortality and morbidity. The use of community health workers and peer supporters offer a way of ensuring the benefits of self-management support observed in the general population are shared by those in minoritized communities.The major databases were searched for existing qualitative evidence of participants’ experiences and perspectives of self-management support for type 2 diabetes delivered by community health workers and peer supporters (CHWPs) in ethnically minoritized populations. The data were analysed using Sekhon’s Theoretical Framework of Acceptability.The results are described within five domains of the framework of acceptability collapsed from seven for reasons of clarity and concision: Affective attitude described participants’ satisfaction with CHWPs delivering the intervention including the open, trusting relationships that developed in contrast to those with clinical providers. In considering Burden and Opportunity Costs, participants reflected on the impact of health, transport, and the responsibilities of work and childcare on their attendance, alongside a lack of resources necessary to maintain healthy diets and active lifestyles. In relation to Cultural Sensitivity participants appreciated the greater understanding of the specific cultural needs and challenges exhibited by CHWPs. The evidence related to Intervention Coherence indicated that participants responded positively to the practical and applied content, the range of teaching materials, and interactive practical sessions. Finally, in examining the impact of Effectiveness and Self-efficacy participants described how they changed a range of health-related behaviours, had more confidence in dealing with their condition and interacting with senior clinicians and benefitted from the social support of fellow participants and CHWPs.Many of the same barriers around attendance and engagement with usual self-management support interventions delivered to general populations were observed, including lack of time and resource. However, the insight of CHWPs, their culturally-sensitive and specific strategies for self-management and their development of trusting relationships presented considerable advantages.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141113677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing diabetes therapy adherence: a comprehensive study on glucometer usability for type 2 diabetes patients 提高糖尿病治疗依从性:关于 2 型糖尿病患者血糖仪易用性的综合研究
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-14 DOI: 10.3389/fcdhc.2024.1328181
Giovanni Toletti, Andrea Boaretto, Chiara Di Loreto, Riccardo Fornengo, Alfonso Gigante, Giovanni Perrone
{"title":"Enhancing diabetes therapy adherence: a comprehensive study on glucometer usability for type 2 diabetes patients","authors":"Giovanni Toletti, Andrea Boaretto, Chiara Di Loreto, Riccardo Fornengo, Alfonso Gigante, Giovanni Perrone","doi":"10.3389/fcdhc.2024.1328181","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1328181","url":null,"abstract":"Self-monitoring of blood glucose (SMBG) is a vital practice for type 2 diabetes (T2DM), and glucometers have the potential to improve therapy adherence. However, characteristics of glucometers improving their usability are underexplored. A knowledge gap exists regarding patients under 65, warranting further research for diabetes care improvement. Thus, this study aims to gather insights on glucometer accessibility, by analyzing the case of the Accu-Chek® Instant glucometer by Roche Diabetes Care GmbH.Starting from a previous study having the objective of investigating devices’ features able to improve SMBG in over 65 T2DM patients, using the same device, we enlarged the scale, designing a survey that collected answers from 1145 patients of the Center and South of Italy, both under and over 65. 957 answers were analyzed, according to a threshold of 50% completion of the answers.Our results show the major characteristics presented in Accu-Chek® Instant are appreciated differently between patients under 65 and over 65, and between patients with or without previous experience with a glucometer.It emerged how Accu-Chek® was perceived as more user-friendly among individuals under 65 compared to those aged 65 and over, where more people had prior experience, indicating how such a glucometer can be particularly helpful for naive patients. The study provides valuable insights to the academic discourse on glucometer features and their influence on therapy adherence.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140979346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of HbA1C and comfort with diabetes self-management among adolescents and young adults with type 1 diabetes 1 型糖尿病青少年患者 HbA1C 与糖尿病自我管理舒适度的关系
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-10 DOI: 10.3389/fcdhc.2024.1304577
Obichi Onwukwe, E. Lundgrin
{"title":"Association of HbA1C and comfort with diabetes self-management among adolescents and young adults with type 1 diabetes","authors":"Obichi Onwukwe, E. Lundgrin","doi":"10.3389/fcdhc.2024.1304577","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1304577","url":null,"abstract":"Adolescents and young adults (AYA) living with type 1 diabetes (T1D) are a vulnerable demographic at risk for sub-optimal glycemic outcomes at a time when they are taking over their diabetes management. The purposes of this study were to examine levels of self-reported comfort with diabetes management tasks among AYA living with T1D and to describe the relationships among comfort levels, sociodemographic factors, and HbA1c. During a routine diabetes care visit, AYA aged 15–23 years old living with T1D received a transition survey to self-assess their comfort level with different diabetesmanagement tasks. Among 161 participants who completed the survey (median age 17 years, median diabetes duration 7 years, 82.3% White, 40.9% female, 66.5% with private insurance, and median HbA1c 8.8%), comfort with diabetes management tasks was generally rated highly (median overall comfort level of 4.5 out of 5), irrespective of race or insurance type. Regression analysis revealed that higher self-reported comfort level with diabetes management tasks was associated with a higher HbA1c (p = 0.006), after controlling for age, sex, race, insurance type, and diabetes duration. These findings suggest that self-reported comfort with independently managing T1D may not be a sufficient metric in assessing AYA patients’ need for further intervention to optimize glycemic outcomes as they transition from pediatric to adult diabetes care, and highlights the importance of continuity of care to support diabetes management during this transitional period.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140990595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is gestational diabetes mellitus in lean women a distinct entity warranting a modified management approach? 瘦弱妇女的妊娠糖尿病是否是一种需要改变管理方法的独特病症?
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-07 DOI: 10.3389/fcdhc.2024.1338597
Pradnyashree Wadivkar, Meredith Hawkins
{"title":"Is gestational diabetes mellitus in lean women a distinct entity warranting a modified management approach?","authors":"Pradnyashree Wadivkar, Meredith Hawkins","doi":"10.3389/fcdhc.2024.1338597","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1338597","url":null,"abstract":"During pregnancy, insulin resistance and impaired insulin secretion may lead to the development of Gestational Diabetes Mellitus (GDM). Although a higher Body Mass Index (BMI) is often cited as a risk factor for the development of GDM, lean pregnant women are also at risk of developing GDM based on evidence from several studies. It is proposed that insulin deficiency (more than insulin resistance) leads to the development of GDM in women with low BMI (BMI <18.5 kg/m2). Neonates of these women are more at risk of preterm birth and small-for-gestational-age. Given this unique pathophysiology and phenotype, this entity needs a modified management approach. This article aims to raise awareness of GDM in lean women to encourage more research on this topic and create a modified management approach.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transition to self-management among emerging adults with type 1 diabetes: a mixed methods study 1 型糖尿病新成人患者向自我管理的过渡:一项混合方法研究
Frontiers in clinical diabetes and healthcare Pub Date : 2024-05-07 DOI: 10.3389/fcdhc.2024.1332159
R. Vitale, Noa Asher, Kaitlyn Shank, Biren Katyal, Liane J. Tinsley, Katharine C. Garvey, Lori M. B. Laffel
{"title":"Transition to self-management among emerging adults with type 1 diabetes: a mixed methods study","authors":"R. Vitale, Noa Asher, Kaitlyn Shank, Biren Katyal, Liane J. Tinsley, Katharine C. Garvey, Lori M. B. Laffel","doi":"10.3389/fcdhc.2024.1332159","DOIUrl":"https://doi.org/10.3389/fcdhc.2024.1332159","url":null,"abstract":"Emerging adulthood is challenging for young people with type 1 diabetes (T1D). This study evaluated transition to diabetes self-management and perceptions of care transfer using mixed methods.An online survey queried demographics, management characteristics, diabetes knowledge, self-care readiness, adherence, and diabetes distress. T-tests compared survey scores between those with self-reported target A1c <7.0% versus ≥7.0%. Pearson correlations assessed associations between A1c and diabetes distress, stratified by A1c <7.0% versus ≥7.0%. Qualitative semi-structured interviews elicited perceptions of young adults; transcripts were analyzed using directed qualitative content analysis.Of 141 participants (30% male, 84% non-Hispanic white) completing the survey, 41% self-reported target A1c <7.0%. Diabetes knowledge and self-care readiness scores did not differ between those with A1c <7.0% versus ≥7.0%, while diabetes distress was lower (45 ± 20 vs 52 ± 20, p=0.01) and adherence higher (77 ± 12 vs 71 ± 14, p=0.02) in those with A1c <7.0% versus ≥7.0%. Diabetes distress was significantly associated with glycemic outcomes in those reporting A1c ≥7.0% (R=0.36, p<0.01). Qualitative analysis (24 participants) revealed five themes and two sub-themes, notable for need for more mental health support, support from others with T1D, benefits of technology for care autonomy, and challenges of obtaining diabetes supplies.Emerging adults with self-reported target A1c endorsed lower diabetes distress and higher adherence than those with elevated A1c. Mental health access, support from others with T1D, technology use, and guidance for supply acquisition may improve transition to self-management and care transfer for emerging adults with T1D.","PeriodicalId":73075,"journal":{"name":"Frontiers in clinical diabetes and healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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