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Individuals and Society 个人与社会
Emerging health threats journal Pub Date : 2020-08-20 DOI: 10.1093/oso/9780190055295.003.0003
D. Barash
{"title":"Individuals and Society","authors":"D. Barash","doi":"10.1093/oso/9780190055295.003.0003","DOIUrl":"https://doi.org/10.1093/oso/9780190055295.003.0003","url":null,"abstract":"This chapter examines threats and responses to threats as they play themselves out in human interactions. One of the significant topics here is crime and punishment—notably, how criminal statutes seek to prevent crime by threatening criminals with punishment sufficient to provide an effective deterrent. There is a long and fascinating history of such efforts, with very little success. This leads to a look at the death penalty in particular and whether it has been effective in preventing capital crimes. The chapter also assesses how people turn to religion when under threat, as well as how religions have often threatened their adherents with after-death retribution for sin, which has long influenced much human anxiety and, in some cases, compliance. Moreover, the chapter reflects on the menace of death plus threats involved in the American gun culture, and race-based and economic anxieties driving the rise of right-wing national populism.","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89335743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Natural World 自然世界
Emerging health threats journal Pub Date : 2020-08-20 DOI: 10.1093/oso/9780190055295.003.0002
D. Barash
{"title":"The Natural World","authors":"D. Barash","doi":"10.1093/oso/9780190055295.003.0002","DOIUrl":"https://doi.org/10.1093/oso/9780190055295.003.0002","url":null,"abstract":"This chapter examines how threats, counterthreats, warnings, feints, and deceptions are found throughout the natural world, in the daily lives of animals and even plants. Indeed, these can be seen in plants with thorns and poisons, as well as in animals growling, roaring, baring teeth, showing and exaggerating their weapons (or pretending to have weapons), misrepresenting their ferocity, puffing themselves up, and generally seeking to intimidate their rivals or potential predators. The chapter then considers the role of honesty versus deception: the evolution of warning coloration, whereby brightly colored poison arrow frogs, for example, inform would-be predators that eating them would be a bad idea; and mimicry, in which animals who are not themselves especially dangerous resemble others that are harmful to their predators and thus gain protection via the “empty threat” the former conveys. This, in turn, speaks to the intriguing question of whether a given threat is real or fake, honest or dishonest, and what difference—if any—this makes. The chapter also explains the hawk–dove model of the variations of animal threat, and looks at vocal threats and animal eavesdropping.","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80599630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospital preparedness in community measles outbreaks-challenges and recommendations for low-resource settings. 社区麻疹疫情中的医院准备工作--针对低资源环境的挑战和建议。
Emerging health threats journal Pub Date : 2015-04-15 eCollection Date: 2015-01-01 DOI: 10.3402/ehtj.v8.24173
Sadia Shakoor, Fatima Mir, Anita K M Zaidi, Afia Zafar
{"title":"Hospital preparedness in community measles outbreaks-challenges and recommendations for low-resource settings.","authors":"Sadia Shakoor, Fatima Mir, Anita K M Zaidi, Afia Zafar","doi":"10.3402/ehtj.v8.24173","DOIUrl":"10.3402/ehtj.v8.24173","url":null,"abstract":"<p><p>We have reviewed various strategies involved in containment of measles in healthcare facilities during community outbreaks. The strategies that are more applicable to resource-poor settings, such as natural ventilation, mechanical ventilation with heating and air-conditioning systems allowing unidirectional air-flow, and protection of un-infected patients and healthcare workers (HCWs), have been examined. Ventilation methods need innovative customization for resource-poor settings followed by validation and post-implementation analysis for impact. Mandatory vaccination of all HCWs with two doses of measles-containing vaccine, appropriate post-exposure prophylaxis of immunocompromised inpatients, and stringent admission criteria for measles cases can contribute toward reduction of nosocomial and secondary transmission within facilities. </p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33099787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of blaIMP4 and blaNDM1 harboring Klebsiella pneumoniae isolates in a university hospital in Malaysia. 马来西亚某大学医院携带肺炎克雷伯菌分离株blaIMP4和blaNDM1的检测
Emerging health threats journal Pub Date : 2015-03-10 eCollection Date: 2015-01-01 DOI: 10.3402/ehtj.v8.26011
Nurul Izzati Hamzan, Chan Yean Yean, Rosliza Abdul Rahman, Habsah Hasan, Zaidah Abdul Rahman
{"title":"Detection of blaIMP4 and blaNDM1 harboring Klebsiella pneumoniae isolates in a university hospital in Malaysia.","authors":"Nurul Izzati Hamzan,&nbsp;Chan Yean Yean,&nbsp;Rosliza Abdul Rahman,&nbsp;Habsah Hasan,&nbsp;Zaidah Abdul Rahman","doi":"10.3402/ehtj.v8.26011","DOIUrl":"https://doi.org/10.3402/ehtj.v8.26011","url":null,"abstract":"<p><p>Background : Antibiotic resistance among Enterobacteriaceae posts a great challenge to the health care service. The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) is attracting significant attention due to its rapid and global dissemination. The infection is associated with significant morbidity and mortality, thus creating challenges for infection control and managing teams to curb the infection. In Southeast Asia, there have been limited reports and subsequent research regarding CRKP infections. Thus, the study was conducted to characterize CRKP that has been isolated in our setting. Methods : A total of 321 K. pneumoniae were included in the study. Each isolate went through an identification process using an automated identification system. Phenotypic characterization was determined using disk diffusion, modified Hodge test, Epsilometer test, and inhibitor combined disk test. Further detection of carbapenemase genes was carried out using polymerase chain reaction and confirmed by gene sequence analysis. Results : All together, 13 isolates (4.05%) were CRKP and the majority of them were resistant to tested antibiotics except colistin and tigercycline. Among seven different carbapenemase genes studied (blaKPC, bla IMP, bla SME, bla NDM, bla IMI, bla VIM, and bla OXA), only two, bla IMP4 (1.87%) and bla NDM1 (2.18%), were detected in our setting. Conclusion : Evidence suggests that the prevalence of CRKP in our setting is low, and knowledge of Carbapenem-resistant Enterobacteriaceae and CRKP has improved and become available among clinicians. </p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v8.26011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33006380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk. 两个恶性循环导致阿尔汉格尔斯克肺结核患者诊断延误。
Emerging health threats journal Pub Date : 2014-08-26 eCollection Date: 2014-01-01 DOI: 10.3402/ehtj.v7.24909
Vladimir N Kuznetsov, Andrej M Grjibovski, Andrej O Mariandyshev, Eva Johansson, Gunnar A Bjune
{"title":"Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk.","authors":"Vladimir N Kuznetsov,&nbsp;Andrej M Grjibovski,&nbsp;Andrej O Mariandyshev,&nbsp;Eva Johansson,&nbsp;Gunnar A Bjune","doi":"10.3402/ehtj.v7.24909","DOIUrl":"https://doi.org/10.3402/ehtj.v7.24909","url":null,"abstract":"<p><strong>Setting: </strong>Delay in tuberculosis (TB) diagnosis increases the infectious pool in the community and the risk of development of resistance of mycobacteria, which results in an increased number of deaths.</p><p><strong>Objective: </strong>To describe patients' and doctors' perceptions of diagnostic delay in TB patients in the Arkhangelsk region and to develop a substantive model to better understand the mechanisms of how these delays are linked to each other.</p><p><strong>Design: </strong>A grounded theory approach was used to study the phenomenon of diagnostic delay. Patients with TB diagnostic delay and doctors-phthisiatricians were interviewed.</p><p><strong>Results: </strong>A model named 'sickness trajectory in health-seeking behaviour among tuberculosis patients' was developed and included two core categories describing two vicious circles of diagnostic delay in patients with TB: 'limited awareness of the importance to contact the health system' and 'limited resources of the health system' and the categories: 'factors influencing health-seeking behaviour' and 'factors influencing the health system effectiveness'. Men were more likely to report patient delay, while women were more likely to report health system delay.</p><p><strong>Conclusions: </strong>To involve people in early medical examinations, it is necessary to increase alertness on TB among patients and to improve health systems in the districts.</p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v7.24909","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32619792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Human brucellosis among pyrexia of unknown origin cases and occupationally exposed individuals in Goa Region, India. 印度果阿地区不明来源发热病例和职业暴露个体中的人间布鲁氏菌病。
Emerging health threats journal Pub Date : 2014-04-22 eCollection Date: 2014-01-01 DOI: 10.3402/ehtj.v7.23846
Ajay D Pathak, Zunjar B Dubal, Swapnil Doijad, Abhay Raorane, Savio Rodrigues, Rajeshwar Naik, Shraddha Naik-Gaonkar, Dewanand R Kalorey, Nitin V Kurkure, Rajesh Naik, Sukhadeo B Barbuddhe
{"title":"Human brucellosis among pyrexia of unknown origin cases and occupationally exposed individuals in Goa Region, India.","authors":"Ajay D Pathak,&nbsp;Zunjar B Dubal,&nbsp;Swapnil Doijad,&nbsp;Abhay Raorane,&nbsp;Savio Rodrigues,&nbsp;Rajeshwar Naik,&nbsp;Shraddha Naik-Gaonkar,&nbsp;Dewanand R Kalorey,&nbsp;Nitin V Kurkure,&nbsp;Rajesh Naik,&nbsp;Sukhadeo B Barbuddhe","doi":"10.3402/ehtj.v7.23846","DOIUrl":"https://doi.org/10.3402/ehtj.v7.23846","url":null,"abstract":"<p><strong>Background: </strong>Brucellosis is a widespread zoonotic infection. This disease is endemic in many parts of Asia, including India. Brucellosis is a major cause of pyrexia of unknown origin (PUO). Persons exposed to infected animals or contaminated animal products are at high risk. Seropositivity among animal handlers, veterinarians and dairy workers has been documented in India. Thus, the present study was aimed to determine prevalence of brucellosis among PUO cases and occupationally exposed individuals.</p><p><strong>Methods: </strong>In this study, serum samples (n=282) from cases of pyrexia of unknown origin (PUO) (n=243), and occupationally exposed individuals (n=39) were collected and tested for brucellosis by Rose Bengal plate test (RBPT), serum agglutination test (SAT), indirect ELISA, IgG and IgM ELISA. Blood culture for isolation of Brucella was performed for 10 serologically positive patients using BACTEC 9050 automated blood culture system. Biochemical tests and PCR techniques were used for confirmation of the isolates.</p><p><strong>Results: </strong>Of the samples tested, 4.25%, 3.54%, 6.02% and 4.96% samples were positive by RBPT, SAT, indirect ELISA and IgG ELISA, respectively. None of the sample was positive for IgM ELISA. Of the 10 blood samples cultured bacteriologically, one Brucella isolate was recovered. The isolate was confirmed as Brucella abortus. Amplification of the bcsp31 and IS711 genes was also observed.</p><p><strong>Conclusion: </strong>Seropositivity for brucellosis was observed among PUO cases, animal handlers and dairy workers in Goa, India. The serological tests showed variable results. One Brucella isolate was obtained by performing blood culture. Confirmation of the case was done rapidly using molecular tools. General awareness about clinical symptoms should be increased which will improve proper diagnosis within short time frame.</p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v7.23846","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32287182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Infectious disease burden in Gujarat (2005-2011): comparison of selected infectious disease rates with India. 古吉拉特邦传染病负担(2005-2011年):与印度选定传染病发病率的比较。
Emerging health threats journal Pub Date : 2014-01-01 DOI: 10.3402/ehtj.v7.22838
Veena Iyer, Gulrez Shah Azhar, Nandini Choudhury, Vidwan Singh Dhruwey, Russell Dacombe, Ashish Upadhyay
{"title":"Infectious disease burden in Gujarat (2005-2011): comparison of selected infectious disease rates with India.","authors":"Veena Iyer,&nbsp;Gulrez Shah Azhar,&nbsp;Nandini Choudhury,&nbsp;Vidwan Singh Dhruwey,&nbsp;Russell Dacombe,&nbsp;Ashish Upadhyay","doi":"10.3402/ehtj.v7.22838","DOIUrl":"https://doi.org/10.3402/ehtj.v7.22838","url":null,"abstract":"<p><strong>Background: </strong>India is known to be endemic to numerous infectious diseases. The infectious disease profile of India is changing due to increased human environmental interactions, urbanisation and climate change. There are also predictions of explosive growth in infectious and zoonotic diseases. The Integrated Disease Surveillance Project (IDSP) was implemented in Gujarat in 2004.</p><p><strong>Methods: </strong>We analysed IDSP data on seven laboratory confirmed infectious diseases from 2005-2011 on temporal and spatial trends and compared this to the National Health Profile (NHP) data for the same period and with other literature. We chose laboratory cases data for Enteric fever, Cholera, Hepatitis, Dengue, Chikungunya, Measles and Diphtheria in the state since well designed vertical programs do not exist for these diseases. Statistical and GIS analysis was done using appropriate software.</p><p><strong>Results: </strong>Our analysis shows that the existing surveillance system in the state is predominantly reporting urban cases. There are wide variations among reported cases within the state with reports of Enteric fever and Measles being less than half of the national average, while Cholera, Viral Hepatitis and Dengue being nearly double.</p><p><strong>Conclusions: </strong>We found some limitations in the IDSP system with regard to the number of reporting units and cases in the background of a mixed health system with multiplicity of treatment providers and payment mechanisms. Despite these limitations, IDSP can be strengthened into a comprehensive surveillance system capable of tackling the challenge of reversing the endemicity of these diseases and preventing the emergence of others.</p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v7.22838","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9697479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Quantifying the effect of media limitations on outbreak data in a global online web-crawling epidemic intelligence system, 2008-2011. 量化2008-2011年全球在线网络爬行流行病情报系统中媒体限制对疫情数据的影响。
Emerging health threats journal Pub Date : 2013-11-08 DOI: 10.3402/ehtj.v6i0.21621
David Scales, Alexei Zelenev, John S Brownstein
{"title":"Quantifying the effect of media limitations on outbreak data in a global online web-crawling epidemic intelligence system, 2008-2011.","authors":"David Scales,&nbsp;Alexei Zelenev,&nbsp;John S Brownstein","doi":"10.3402/ehtj.v6i0.21621","DOIUrl":"https://doi.org/10.3402/ehtj.v6i0.21621","url":null,"abstract":"<p><strong>Background: </strong>This is the first study quantitatively evaluating the effect that media-related limitations have on data from an automated epidemic intelligence system.</p><p><strong>Methods: </strong>We modeled time series of HealthMap's two main data feeds, Google News and Moreover, to test for evidence of two potential limitations: first, human resources constraints, and second, high-profile outbreaks \"crowding out\" coverage of other infectious diseases.</p><p><strong>Results: </strong>Google News events declined by 58.3%, 65.9%, and 14.7% on Saturday, Sunday and Monday, respectively, relative to other weekdays. Events were reduced by 27.4% during Christmas/New Years weeks and 33.6% lower during American Thanksgiving week than during an average week for Google News. Moreover data yielded similar results with the addition of Memorial Day (US) being associated with a 36.2% reduction in events. Other holiday effects were not statistically significant. We found evidence for a crowd out phenomenon for influenza/H1N1, where a 50% increase in influenza events corresponded with a 4% decline in other disease events for Google News only. Other prominent diseases in this database - avian influenza (H5N1), cholera, or foodborne illness - were not associated with a crowd out phenomenon.</p><p><strong>Conclusions: </strong>These results provide quantitative evidence for the limited impact of editorial biases on HealthMap's web-crawling epidemic intelligence.</p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v6i0.21621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31846877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
EpiBasket: how e-commerce tools can improve epidemiological preparedness. EpiBasket:电子商务工具如何改善流行病学防范。
Emerging health threats journal Pub Date : 2013-10-31 DOI: 10.3402/ehtj.v6i0.19748
Weijia Xing, Gilles Hejblum, Alain-Jacques Valleron
{"title":"EpiBasket: how e-commerce tools can improve epidemiological preparedness.","authors":"Weijia Xing,&nbsp;Gilles Hejblum,&nbsp;Alain-Jacques Valleron","doi":"10.3402/ehtj.v6i0.19748","DOIUrl":"https://doi.org/10.3402/ehtj.v6i0.19748","url":null,"abstract":"<p><strong>Background: </strong>Should an emerging infectious disease outbreak or an environmental disaster occur, the collection of epidemiological data must start as soon as possible after the event's onset. Questionnaires are usually built de novo for each event, resulting in substantially delayed epidemiological responses that are detrimental to the understanding and control of the event considered. Moreover, the public health and/or academic institution databases constructed with responses to different questionnaires are usually difficult to merge, impairing necessary collaborations. We aimed to show that e-commerce concepts and software tools can be readily adapted to enable rapid collection of data after an infectious disease outbreak or environmental disaster. Here, the 'customers' are the epidemiologists, who fill their shopping 'baskets' with standardised questions.</p><p><strong>Methods: </strong>For each epidemiological field, a catalogue of questions is constituted by identifying the relevant variables based on a review of the published literature on similar circumstances. Each question is tagged with information on its source papers. Epidemiologists can then tailor their own questionnaires by choosing appropriate questions from this catalogue. The software immediately provides them with ready-to-use forms and online questionnaires. All databases constituted by the different EpiBasket users are interoperable, because the corresponding questionnaires are derived from the same corpus of questions.</p><p><strong>Results: </strong>A proof-of-concept prototype was developed for Knowledge, Attitudes and Practice (KAP) surveys, which is one of the fields of the epidemiological investigation frequently explored during, or after, an outbreak or environmental disaster. The catalogue of questions was initiated from a review of the KAP studies conducted during or after the 2003 severe acute respiratory syndrome epidemic.</p><p><strong>Conclusion: </strong>Rapid collection of standardised data after an outbreak or environmental disaster can be facilitated by transposing the e-commerce paradigm to epidemiology, taking advantage of the powerful software tools already available.</p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v6i0.19748","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31826952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Human enterovirus 71 epidemics: what's next? 人类肠道病毒71型流行:下一步是什么?
Emerging health threats journal Pub Date : 2013-09-10 DOI: 10.3402/ehtj.v6i0.19780
Cyril C Y Yip, Susanna K P Lau, Patrick C Y Woo, Kwok-Yung Yuen
{"title":"Human enterovirus 71 epidemics: what's next?","authors":"Cyril C Y Yip,&nbsp;Susanna K P Lau,&nbsp;Patrick C Y Woo,&nbsp;Kwok-Yung Yuen","doi":"10.3402/ehtj.v6i0.19780","DOIUrl":"https://doi.org/10.3402/ehtj.v6i0.19780","url":null,"abstract":"<p><p>Human enterovirus 71 (EV71) epidemics have affected various countries in the past 40 years. EV71 commonly causes hand, foot and mouth disease (HFMD) in children, but can result in neurological and cardiorespiratory complications in severe cases. Genotypic changes of EV71 have been observed in different places over time, with the emergence of novel genotypes or subgenotypes giving rise to serious outbreaks. Since the late 1990s, intra- and inter-typic recombination events in EV71 have been increasingly reported in the Asia-Pacific region. In particular, 'double-recombinant' EV71 strains belonging to a novel genotype D have been predominant in mainland China and Hong Kong over the last decade, though co-circulating with a minority of other EV71 subgenotypes and coxsackie A viruses. Continuous surveillance and genome studies are important to detect potential novel mutants or recombinants in the near future. Rapid and sensitive molecular detection of EV71 is of paramount importance in anticipating and combating EV71 outbreaks. </p>","PeriodicalId":72898,"journal":{"name":"Emerging health threats journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/ehtj.v6i0.19780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31802071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 144
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