{"title":"Early and midterm efficacy of oxiplex gel on postoperative pain intensity, physical disability, and musculoskeletal power in patients undergoing lumbar discectomy","authors":"Alireza Tabibkhooei, Maziar Azar, Mohsen Nabiuni, Javid Jahandideh, Mohsen Benam, Farid Qoorchi Moheb Seraj, Feizollah Ebrahimnia, Ali Moradi","doi":"10.1186/s41984-024-00266-9","DOIUrl":"https://doi.org/10.1186/s41984-024-00266-9","url":null,"abstract":"Carboxymethylcellulose/polyethylene oxide, also known as Oxiplex gel, is commonly used during lumbar discectomy operations. It serves to cover the surgical site, preventing adhesions and providing relief from pain and symptoms. However, there is ongoing debate regarding the extent of its beneficial effects on postoperative pain intensity, level of disability, and overall improvement of musculoskeletal conditions. Therefore, the objective of this study is to evaluate the advantages and limitations of using Oxiplex gel in lumbar laminectomy procedures specifically for herniated discs. A randomized controlled trial was conducted on 56 consecutive patients who were candidates for unilateral lumbar discectomy on one lumbar surface. The patients were chosen based on their clinical manifestations and imaging findings. After the initial assessment, the patients underwent either laminectomy or laminotomy surgery. Following the surgery, the patients were randomly assigned to either the intervention group (receiving Oxiplex gel) or the control group. This assignment was done using a computerized random number generator. Assessments were conducted before the operation, as well as 3 and 6 months post-surgery for all patients. There was no significant difference found between the Oxiplex gel and control groups in terms of radicular and low back pain intensity, as well as disability scores, at different time points after surgery (p = 0.336, p = 0.65, and p = 0.336, respectively). Additionally, there were no significant differences found in the prevalence of sexual or sphincteric disorders between the two groups during postoperative assessments (p = 0.639 and p = 0.15, respectively). Furthermore, no significant differences were observed in the results of the postsurgical neuromuscular evaluation under different lower extremities conditions between the two groups. Based on our findings, it was observed that Oxiplex gel did not demonstrate any improvement in post-unilateral lumbar discectomy symptoms or musculoskeletal power.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141506478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sabouri, Aref Famili Dogonchi, Mehdi Shafiei, Donya Shaybeni Tehrani
{"title":"Survival rate of patient with glioblastoma: a population-based study","authors":"M. Sabouri, Aref Famili Dogonchi, Mehdi Shafiei, Donya Shaybeni Tehrani","doi":"10.1186/s41984-024-00294-5","DOIUrl":"https://doi.org/10.1186/s41984-024-00294-5","url":null,"abstract":"","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141376701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aly Ibrahim, Khaled Elshazly, Mohamed A. R. AbdelFatah, Abdelrahman El-Gayar, Sameh Hefny
{"title":"Management of spontaneous pyogenic spondylodiscitis: a descriptive cohort study","authors":"Aly Ibrahim, Khaled Elshazly, Mohamed A. R. AbdelFatah, Abdelrahman El-Gayar, Sameh Hefny","doi":"10.1186/s41984-024-00299-0","DOIUrl":"https://doi.org/10.1186/s41984-024-00299-0","url":null,"abstract":"Spontaneous spondylodiscitis (SD) is an inflammation of the vertebral endplate and the intervertebral disc with no prior surgery or intervention. The treatment of spontaneous pyogenic SD mainly consists of systemic antibiotics and rest. Some cases require surgery due to failure of medical treatment or due to neurological compromise. Due to the disease heterogeneity, there are no standardized, widely adopted treatment protocols. We conducted this study to assess the clinical outcome of the different treatment modalities. This is a retrospective analysis of prospectively collected data of patients with spontaneous non-tuberculous spondylodiscitis. Thirty-eight patients were identified, including 14 males and 24 females. The mean age was 49 years. Twenty-three patients underwent surgery from the start while 15 patients received conservative medical treatment. Among the latter, 8 patients showed disease progression and required surgical intervention. The ODI/NDI at 1 year (mean = 8) was significantly better than before treatment (mean = 18). Among 11 patients with motor deficit at presentation, 8 improved and 3 remained stable. There were 14 complications, including 11 minor and 3 major, requiring one revision surgery. Surgical decompression and debridement with or without instrumented fusion for complicated SD cases is a safe and effective treatment modality. Close follow-up is needed in case of conservative treatment for early detection of treatment failure and disease progression. Baseline characteristic variabilities in patients with spontaneous pyogenic SD could predict conservative treatment failure, but this needs to be validated in larger series.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141252237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: additional considerations for giant pituitary adenoma resection strategy","authors":"Andrew B. Yang, Fraser C. Henderson","doi":"10.1186/s41984-024-00305-5","DOIUrl":"https://doi.org/10.1186/s41984-024-00305-5","url":null,"abstract":"<p>We read with interest the recently published retrospective cohort study “Giant invasive pituitary adenomas: surgical approach selection paradigm and its influence on the outcome—case series” by Dr. Saad, et al. highlighting the persistent role in the treatment algorithm for a transcranial approach for <i>giant</i> pituitary adenomas, as present frequently in our low-resource setting in rural Kenya. In our center, we have been learning firsthand the difficulties surrounding maximum safe resection of giant adenomas. We remain humbled by the reality of the challenges in decompressing the optic apparatus, minimizing tumor burden to prevent recurrence, preserving pituitary and hypothalamic functions, and stewarding patient resources in what can be a very expensive undertaking, even in charitable low- and middle-income country (LMIC) hospitals.</p><p>We are grateful to the authors for illustrating in the African setting the importance of including a transcranial approach in the treatment plan for many of these giant adenomas. Although the endonasal approach has become the widespread method of complete resection in many areas of the world over the past two decades, in sub-Saharan Africa, where pituitary adenomas are the second most common brain tumor, the endoscopic endonasal approach (EEA) was only adopted in our center about two years ago [1, 2]. EEA adoption in LMIC settings remains relatively lower in comparison with high-resource academic centers where the EEA continues to be refined to ever-higher heights of efficacy [2, 3].</p><p>We have come to better understand the reasons for this reticence in applying EEA to every pituitary adenoma. First, the learning curve for surgeons and assistants for the EEA can be steep, and adoption is more likely to occur at any given institution if that institution has staff who have been trained in the approach, to avoid postoperative complications like cerebrospinal fluid leaks and hypopituitarism [2,3,4]. Second, the capital resources required to purchase and maintain necessary endoscopic equipment and to train individuals on its use and handling are high [3]. Third is the fact that pituitary tumors tend to present later in their course in LMIC due to a variety of social and economic factors [5]. This means that tumors tend to be larger, of a firmer consistency, and more densely adherent to critical structures such as the Circle of Willis and the pituitary gland and hypothalamus by the time a neurosurgeon becomes involved. Fourth is the significant expense of MRI facilities and intraoperative navigation leading to a dearth of these capabilities in sub-Saharan Africa [6].</p><p>To illustrate one of our humbling experiences, we reference a recent case of a 50-year-old woman who presented to an eye clinic with 5 years of progressive bilateral visual deficits and was referred to our neurosurgery clinic. She arrived to us 11 months later with complete right eye blindness and the ability to count fingers up to 1 m a","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141168377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Jribi, Fatma Dhouib, Wicem Siala, Nejla Fourati, Jamel Daoud
{"title":"Cerebellar liponeurocytoma: clinico-epidemiological, pathological, radiological, genetic, therapeutic and evolutionary characteristics—a review of the literature","authors":"Ahmed Jribi, Fatma Dhouib, Wicem Siala, Nejla Fourati, Jamel Daoud","doi":"10.1186/s41984-024-00304-6","DOIUrl":"https://doi.org/10.1186/s41984-024-00304-6","url":null,"abstract":"Cerebellar liponeurocytoma is a rare benign tumor of the central nervous system affecting adults and mainly the posterior fossa. Its positive diagnosis remains difficult due to its rarity and the presence of several differential diagnoses including medulloblastoma. The oncogenetic mechanism, the therapeutic modalities and results are still currently under study. Very few cases have been published in the literature. The aim of this review is to report, through the available data, all its various clinico-epidemiological, pathological, radiological, genetic, therapeutic and evolutionary features. In fact, this tumor is associated with a slow-growing character, appears in young adulthood with slight female predominance and is often manifested by intracranial hypertension symptoms. It is pathologically characterized by a focal component of lipomatous differentiation and a low proliferation index. It is usually presented in imaging by a well-limited mass with signal attenuation for fatty tissue and heterogeneous contrast. No mutation has been identified yet. The gold standard treatment of this tumor is maximal complete resection. The evolutionary profile is marked by frequent local recurrence. Radiotherapy could be discussed in case of recurrence, incomplete surgery, inoperable cases and cases with high proliferation index, and there is to date no proof of benefit for systemic treatment. Due to the numerous similarities of this entity with medulloblastoma, it should be always evoked face to any suspicion of medulloblastoma in adults in order to avoid a wrong overtreatment.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141168368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammud Ahmud Salim, Hossam Elnoamany, Mohammed Adel Dorrah, Zahraa M. Mahdy, Ahmed Said Mansour
{"title":"Surgical outcome of isolated benign peripheral nerve sheath tumors without neurofibromatosis","authors":"Mohammud Ahmud Salim, Hossam Elnoamany, Mohammed Adel Dorrah, Zahraa M. Mahdy, Ahmed Said Mansour","doi":"10.1186/s41984-024-00297-2","DOIUrl":"https://doi.org/10.1186/s41984-024-00297-2","url":null,"abstract":"Benign peripheral nerve sheath tumors (BPNSTs) include schwannomas and neurofibromas. About 10% of soft tissue sarcomas are malignant peripheral nerve sheath tumors (MPNSTs), which are invasive and aggressive tumors. These can happen occasionally or after radiation exposure. Up to 90% of schwannomas are made up of differentiated neoplastic Schwann cells. Malignant transformation of schwannomas is rare. We collected the medical records of all patients (including their family histories), performed comprehensive physical and neurological assessments, and checked for the presence of a Tinel-like sign, as well as screening for neurofibromatosis (NF) signs. Magnetic resonance imaging (MRI), nerve conduction studies, and ultrasound were done for all cases. We have operated on 21 patients with age range 29–52 years. The mean age was 39.4 years. 14 of these patients were females and 7 were males. The presenting symptoms were just swelling at nerve site in 14 patients, spontaneous pain at the nerve sites in 7 patients, and sensory deficit at the nerve distribution sites in 9 patients. The other 12 patients were sensory intact and only 7 patients had motor deficit. Postoperatively all patients had improved motor and sensory deficit and none of intact patients were worsened. Preoperatively we did MRI to show important nearby vascular structure anatomical abnormalities and we ordered nerve studies to all patients that showed abnormalities, which was only in 9 patients. Gross total resection was done in 18 patients and other 3 cases had partial resection to avoid sensory and motor deficits. The pathological analysis revealed 11 schwannomas and 10 neurofibromas. With 1 year follow up there was no recurrence in any patients. Benign pheripheral nerve sheath tumours are safely resected without increased sensory and motor deficits after surgery and with improve clinical outcome with no recurrence on follow up.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141168488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yao Christian Hugues Dokponou, Moussa Elmi Saad, Fresnel Lutece Ontsi Obame, Napoleão Imbunhe, Salami Mohcine, Abad Cherif El Asri, Miloud Gazzaz
{"title":"Surgical management of cervical intramedullary cavernoma: case report and systematic review of the literature","authors":"Yao Christian Hugues Dokponou, Moussa Elmi Saad, Fresnel Lutece Ontsi Obame, Napoleão Imbunhe, Salami Mohcine, Abad Cherif El Asri, Miloud Gazzaz","doi":"10.1186/s41984-024-00300-w","DOIUrl":"https://doi.org/10.1186/s41984-024-00300-w","url":null,"abstract":"Cavernous malformations can occur throughout the cerebral nervous system, most commonly located in the supratentorial compartment. The intramedullary location is rare and accounts for approximately 2.4% to 5% of all spinal vascular tumors. The cervical cord location and its clinical manifestations are underreported. The authors report a case of spinal cord compression at the C5–C6 level by a cervical intramedullary cavernoma with a systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and meta-analysis guidelines. Relevant studies (1980 to 2023) that reported patients with cervical intramedullary cavernoma were identified from PubMed databases. A total of 29 studies reporting 423 patients were included in this study with a mean age of 40.5 ± 6.3 years old. The overall male-to-female ratio was 1:2.5 with a median duration of follow-up of 46 months [18.5–63.9]. The type of resection as well as the patient’s outcome was also reported. Intramedullary cavernous angiomas are rare. Early surgical total resection of the symptomatic lesions in adequate conditions is crucial for good outcomes.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141168487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computed tomography-guided trigeminal tractotomy-nucleotomy for refractory chronic craniofacial pain: a case report","authors":"Cetin Genc, Aydin Aydoseli","doi":"10.1186/s41984-024-00302-8","DOIUrl":"https://doi.org/10.1186/s41984-024-00302-8","url":null,"abstract":"","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed M. Aziz, Hesham Radwan, Ahmed Kamel Basha, Hany Eldawoody
{"title":"Evaluation of minimally invasive percutaneous transpedicular screw fixation as an evolving modality for the treatment of thoracolumbar fractures","authors":"Mohamed M. Aziz, Hesham Radwan, Ahmed Kamel Basha, Hany Eldawoody","doi":"10.1186/s41984-024-00295-4","DOIUrl":"https://doi.org/10.1186/s41984-024-00295-4","url":null,"abstract":"","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141102878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}