Chemistry methods : new approaches to solving problems in chemistry最新文献_第4页

Polymer, Water, and Salt Partitioning in Complex Coacervates Characterized by Femtosecond Stimulated Raman Microscopy 用飞秒受激拉曼显微镜表征复杂凝聚体中聚合物、水和盐的分配

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-30 DOI: 10.1002/cmtd.202500005

Francisco van Riel Neto, Carolin Borbeck, Torben Henning Saatkamp, Maxine Kenny, Stephan Schmidt, Peter Gilch

{"title":"Polymer, Water, and Salt Partitioning in Complex Coacervates Characterized by Femtosecond Stimulated Raman Microscopy","authors":"Francisco van Riel Neto, Carolin Borbeck, Torben Henning Saatkamp, Maxine Kenny, Stephan Schmidt, Peter Gilch","doi":"10.1002/cmtd.202500005","DOIUrl":"https://doi.org/10.1002/cmtd.202500005","url":null,"abstract":"Complex coacervates can form through liquid–liquid phase separation in aqueous solutions containing oppositely charged macromolecules. This process results in macromolecule-rich droplets (coacervate phase) coexisting with a macromolecule-depleted supernatant phase. Here, femtosecond stimulated Raman microscopy (FSRM) is introduced as a tool to rapidly analyze both the supernatant and coacervate phases of complex coacervates. The well-known polyelectrolyte pair poly(diallyldimethylammonium chloride) and poly(4-styrenesulfonate) is investigated. Coacervate formation is induced by the addition of KBr and NH4SCN as a Raman-active salt. For both salts, the partitioning of polymer and water between the coacervate droplets and the supernatant phase is quantified. For the Raman-active salt NH4SCN, its partitioning between phases was also monitored. NH4SCN was found to be enriched in the coacervate phase, as confirmed by FTIR spectroscopy. Overall, FSRM proves to be a valuable tool for collecting new data on coacervate composition requiring only low sample volumes and simple sample preparation, while offering convenient data acquisition.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202500005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Testing Protocols for Obtaining Reliable Pair Distribution Functions from Laboratory X-Ray Sources Using PDFgetX3 使用PDFgetX3从实验室x射线源获得可靠的对分布函数的测试协议

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-30 DOI: 10.1002/cmtd.202500001

Till Schertenleib, Daniel Schmuckler, Yucong Chen, Geng Bang Jin, Wendy L. Queen, Simon J. L. Billinge

{"title":"Testing Protocols for Obtaining Reliable Pair Distribution Functions from Laboratory X-Ray Sources Using PDFgetX3","authors":"Till Schertenleib, Daniel Schmuckler, Yucong Chen, Geng Bang Jin, Wendy L. Queen, Simon J. L. Billinge","doi":"10.1002/cmtd.202500001","DOIUrl":"10.1002/cmtd.202500001","url":null,"abstract":"Herein, data acquisition protocols are explored and data reduction protocols are improved using PDFgetX3 to obtain reliable data for atomic pair distribution function (PDF) analysis from a laboratory-based Mo Kα X-ray source. A variable counting scheme is described that preferentially counts in the high-angle region of the diffraction pattern. The effects on the resulting PDF are studied by varying the overall count time, the use of Soller slits, and limiting the out-of-plane divergence of the incident beam. The protocols are tested using an amorphous silica and a quartz sample. A Python script is presented that allows the comparison of PDFs obtained from different instruments and different acquisition protocols and does automatic uncertainty estimation and error propagation. A modification to the current PDFgetX3 data corrections to take care of sample absorption is also presented, which was previously neglected in the use of that program for high-energy synchrotron X-ray data.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202500001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid, In Situ and Non-Destructive Analysis for the Evaluation of Microplastics Degradation in Water Via Haze Measurement 基于雾霾测量的水中微塑料降解的快速、原位和无损分析

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-28 DOI: 10.1002/cmtd.202400047

Rossella Greco, Lucía Baxauli-Marin, Javier Fernández-Catalá, Viktorija Pankratova, Claudiu Bulbucan, Karina Thånell, Wei Cao

{"title":"Rapid, In Situ and Non-Destructive Analysis for the Evaluation of Microplastics Degradation in Water Via Haze Measurement","authors":"Rossella Greco, Lucía Baxauli-Marin, Javier Fernández-Catalá, Viktorija Pankratova, Claudiu Bulbucan, Karina Thånell, Wei Cao","doi":"10.1002/cmtd.202400047","DOIUrl":"10.1002/cmtd.202400047","url":null,"abstract":"The presence of microplastics (MPs) in water represents a current problem for marine life and a future serious issue for human health. This is pushing towards new approaches for the removal of MPs and, hence, their characterization and evaluation, which up to now has represented a limit for tentative procedures for their degradation. Herein, we reported on a new facile, in situ and non-destructive approach for the qualitative analysis of polystyrene and polymethylmethacrylate MPs in water and their evaluation in photocatalytic degradation with the use of Co3O4@Co(OH)2 heterostructures. The use of haze measurements allows to see the changes in light scattering of the MPs aqueous dispersions during the photocatalytic degradation and to know in situ the degradation of the MPs in the catalytic process. Significant changes in haze values were found in photocatalysis with Co3O4@Co(OH)2, in contrast to no variations in control test using Co(OH)2 and Co3O4. Synchrotron-radiation based scanning transmission x-ray spectroscopy further denotes strong interactions between the heterostructures with MPs and oxidization of the latter. The possible comparison of different techniques suggests that haze measurements could be a valid and cost-efficient methodology for the future evaluation of photocatalytic degradation of MPs in water.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 6","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial Stages of Gas Diffusion Electrode Flow-Cell CO2 Electrolysis—Monitoring via Synergetic Online Mass Spectrometry and Rapid Sample-Trapping Gas Chromatography 气体扩散电极流动电池CO2电解的初始阶段-通过协同在线质谱法和快速样品捕获气相色谱法监测

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-27 DOI: 10.1002/cmtd.202400092

Christina Martens, Bernhard Schmid, Albert Luft, Nevfel Sarioglu, Hermann Tempel, Rüdiger-A. Eichel

{"title":"Initial Stages of Gas Diffusion Electrode Flow-Cell CO2 Electrolysis—Monitoring via Synergetic Online Mass Spectrometry and Rapid Sample-Trapping Gas Chromatography","authors":"Christina Martens, Bernhard Schmid, Albert Luft, Nevfel Sarioglu, Hermann Tempel, Rüdiger-A. Eichel","doi":"10.1002/cmtd.202400092","DOIUrl":"10.1002/cmtd.202400092","url":null,"abstract":"High-performance gas diffusion electrodes (GDEs) are crucial for large-scale CO2-electrolysis. During initial electrode polarization, the startup procedure plays a critical role in determining the subsequent performance of electrodes. This phase influences the course and rate of catalyst formation, as well as electrode-wetting, and must be carefully managed to prevent initial electrode damage. Maintaining ideal conditions despite added constraints and complexity during scale-up requires in-depth understanding of these operational phases. However, progress is limited by the current inability to rapidly analyze product gases. To address this, we present a modified gas chromatography (GC) method capable of sampling every 30 seconds within a limited timeframe, maintaining full data quality. This method was compared and combined with online mass spectrometry (MS), which is faster but comes with calibration challenges and spectral overlaps. We explore the strengths, limitations, and potential synergies of both techniques during electrolyzer startup and for current steps on GDEs with different catalyst layer designs. Experimental results reveal that concentration gradients and additional electrode-wetting under load primarily occur within the first two minutes. Both fast-GC and MS methods are effective for product gas analysis within this critical timeframe. We demonstrate the calibration of MS fragmentation signal corrections using simultaneous GC data.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 8","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequential Polymerization of Nitrogen at High Pressures 高压下氮气的序贯聚合

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-26 DOI: 10.1002/cmtd.202400074

Huawei Chen, Mohammad F. Mahmood, Alexander F. Goncharov

引用次数: 0

Frontiers of Synchrotron Methods for Actinide Science 锕系元素科学同步加速器方法的前沿

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-25 DOI: 10.1002/cmtd.202400073

Dr. Damien Prieur, Dr. Lucia Amidani, Dr. Elena F. Bazarkina, Dr. Christoph Hennig, Dr. Eleanor Lawrence Bright, Dr. Andre Rossberg, Clara L. Silva, Prof. Dr. Kristina O. Kvashnina

{"title":"Frontiers of Synchrotron Methods for Actinide Science","authors":"Dr. Damien Prieur, Dr. Lucia Amidani, Dr. Elena F. Bazarkina, Dr. Christoph Hennig, Dr. Eleanor Lawrence Bright, Dr. Andre Rossberg, Clara L. Silva, Prof. Dr. Kristina O. Kvashnina","doi":"10.1002/cmtd.202400073","DOIUrl":"10.1002/cmtd.202400073","url":null,"abstract":"The complexity of actinide chemistry and physics, driven by intricate electronic structures, variable oxidation states, and radioactive properties, poses significant challenges for scientific exploration. Synchrotron radiation methods, including X-ray Absorption Spectroscopy (XAS), X-ray Emission Spectroscopy (XES), high energy resolution fluorescence detection (HERFD) XAS, resonant inelastic X-ray scattering (RIXS) and X-ray Diffraction (XRD), have proven to be transformative tools in addressing these challenges. These advanced methods enable detailed investigations of local environments, oxidation states, and phase transitions, offering critical insights into nuclear fuel management, environmental remediation, and the development of advanced materials. This work highlights the developments and applications of synchrotron-based methods and their analysis for studying actinide systems at the Rossendorf beamline at the ESRF (Grenoble, France). The results underscore the pivotal role of the combination of synchrotron techniques and advanced theoretical modeling to unravel the complexities of actinide materials.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 8","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing Viral Proteases for Cellular and Molecular Engineering 利用病毒蛋白酶进行细胞和分子工程

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-22 DOI: 10.1002/cmtd.202400098

Mingguang Cui, Tien-Hung Lan, Yubin Zhou

{"title":"Harnessing Viral Proteases for Cellular and Molecular Engineering","authors":"Mingguang Cui, Tien-Hung Lan, Yubin Zhou","doi":"10.1002/cmtd.202400098","DOIUrl":"10.1002/cmtd.202400098","url":null,"abstract":"Viral proteases (VIPs) are naturally evolved enzymes that cleave viral polyproteins into functional proteins with remarkable specificity, orthogonality, and minimal cytotoxicity in mammalian cells. These unique properties have positioned VIPs as indispensable tools in synthetic biology, enabling precise and programmable control of protein activity. By recognizing defined cleavage sites, VIP-based systems can facilitate targeted protein release or degradation, driving innovations in the design of genetically encoded sensors and actuators. Engineered VIP systems have been applied to record dynamic cellular events, modulate signaling pathways, and regulate gene expression with high precision. Their versatility and reliability have unlocked transformative applications across diverse fields, including neural circuit mapping, high-throughput drug discovery, and targeted cancer therapies. The exceptional precision, robustness, and safety of VIPs continue to advance their role as cornerstone technologies in synthetic biology, thereby empowering the creation of next-generation molecular tools and therapeutic innovation.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering Important Metabolic Pathways through Reaction Pair Prediction with a Siamese Transformer Network 通过暹罗变压器网络的反应对预测来破译重要的代谢途径

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-22 DOI: 10.1002/cmtd.202400064

Han Bao, Xinxin Wang, Jinhui Zhao, Bin Wang, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu

{"title":"Deciphering Important Metabolic Pathways through Reaction Pair Prediction with a Siamese Transformer Network","authors":"Han Bao, Xinxin Wang, Jinhui Zhao, Bin Wang, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu","doi":"10.1002/cmtd.202400064","DOIUrl":"10.1002/cmtd.202400064","url":null,"abstract":"Important pathway identification is essential for unraveling biological mechanisms in functional metabolomics. However, current pathway enrichment is often biased toward well-characterized pathways due to low annotation rates in untargeted metabolomics and incomplete pathway coverage. It leads to potential misinterpretation of metabolomics data. Herein, Siamese transformer reaction pair (STRP) prediction, an approach for important pathway exploration in metabolomics, is introduced. STRP leverages a weight-sharing Siamese network and a multihead attention Transformer encoder to predict metabolic reaction pairs, utilizing molecular fingerprints derived from either known metabolites or tandem mass spectra of unannotated metabolic features. Pathway labels are then deduced for metabolic features from known pathway metabolites within the reaction pairs. STRP can achieve crossvalidation metrics of 98.10%/98.13% accuracy, 97.98%/98.01% precision, 97.94%/97.97% recall, 97.96%/97.99% F1 score, and 99.56%/99.57% area under the receiver operating characteristic curve of spectral pairs in ESI+/ESI− modes. It is applied to metabolomics datasets from prostate cancer and diabetic retinopathy. STRP successfully identifies and interprets important metabolic pathways, demonstrating its robust utility for important pathway identification. Besides, STRP-based molecular network showcases potential application in metabolome annotation. This approach reveals a significant advancement in leveraging high-resolution mass spectrometry-based metabolomics data, with the potential to transform understanding of complex biological processes.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 6","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly Sensitive, Low-Cost Deep-UV Resonant Raman Microspectroscopy Systems 高灵敏度，低成本的深紫外共振拉曼微光谱系统

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-21 DOI: 10.1002/cmtd.202500006

Joseph Harrington, Vsevolod Cheburkanov, Mykyta Kizilov, Ilya Kulagin, Georgi I. Petrov, Vladislav V. Yakovlev

{"title":"Highly Sensitive, Low-Cost Deep-UV Resonant Raman Microspectroscopy Systems","authors":"Joseph Harrington, Vsevolod Cheburkanov, Mykyta Kizilov, Ilya Kulagin, Georgi I. Petrov, Vladislav V. Yakovlev","doi":"10.1002/cmtd.202500006","DOIUrl":"10.1002/cmtd.202500006","url":null,"abstract":"Deep-UV resonant Raman (DUVRR) spectroscopy is a powerful technique for chemical and structural analysis, offering significant advantages, including increased signal enhancement, reduced fluorescence interference, and higher spatial resolution. However, the high cost and complexity of traditional Deep-UV (DUV) excitation sources have limited its broader adoption. Herein, a novel, cost-effective DUVRR microscopy system utilizing a low-pressure mercury lamp emitting at 253.7 nm as the excitation source is presented. The system achieves efficient Raman filtering through a mercury vapor cell and incorporates multiplexed fiber optics for hyperspectral imaging. This design demonstrates robust performance across diverse applications, including fluorescence suppression, polymer characterization, biological imaging, and ultrasensitive detection of environmental contaminants. The integration of an optical cavity for signal enhancement enables the detection of nanomolar concentrations of analytes, paving the way for high-sensitivity measurements in biomedical and environmental research. These advancements demonstrate the practicality of affordable, high-performance DUVRR systems for widespread application.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202500006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

X-Ray Absorption Studies of Local Structure of Dilute Ionic Species in Molten Salts 熔盐中稀离子局部结构的x射线吸收研究

IF 3.6

Chemistry methods : new approaches to solving problems in chemistry Pub Date : 2025-04-15 DOI: 10.1002/cmtd.202400097

Kaifeng Zheng, Nirmalendu Patra, Nicholas Marcella, Alexander S. Ivanov, James F. Wishart, Alejandro R. Ballesteros, Ruchi Gakhar, Sheng Dai, Santanu Roy, Vyacheslav Bryantsev, Simerjeet K. Gill, Anatoly I. Frenkel

{"title":"X-Ray Absorption Studies of Local Structure of Dilute Ionic Species in Molten Salts","authors":"Kaifeng Zheng, Nirmalendu Patra, Nicholas Marcella, Alexander S. Ivanov, James F. Wishart, Alejandro R. Ballesteros, Ruchi Gakhar, Sheng Dai, Santanu Roy, Vyacheslav Bryantsev, Simerjeet K. Gill, Anatoly I. Frenkel","doi":"10.1002/cmtd.202400097","DOIUrl":"10.1002/cmtd.202400097","url":null,"abstract":"Molten salts are crucial materials with exceptional properties that make them suitable for applications such as heat transfer media, coolants, and liquid fuels in molten salt nuclear reactors and the concentrated solar power industry. Understanding their properties requires unraveling the intricate mysteries of their structure. To achieve this, advanced characterization tools are essential. Among various techniques, X-ray absorption fine structure (XAFS) stands out as a versatile method capable of studying the structure of molten salts under in situ conditions. This review highlights recent advancements in the application of XAFS for investigating the local structure of molten salts, discusses its limitations and potential improvements, and explores complementary approaches such as simulations, machine learning, and correlative experimental methods.","PeriodicalId":72562,"journal":{"name":"Chemistry methods : new approaches to solving problems in chemistry","volume":"5 7","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cmtd.202400097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0