Cerebral cortex communications最新文献_第5页

Neuroanatomical correlates of working memory performance in Neurofibromatosis 1. 神经纤维瘤病患者工作记忆表现的神经解剖学相关性

Cerebral cortex communications Pub Date : 2022-05-19 eCollection Date: 2022-01-01 DOI: 10.1093/texcom/tgac021

Cameron Sawyer, Jonathan Green, Ben Lim, Gorana Pobric, JeYoung Jung, Grace Vassallo, D Gareth Evans, Charlotte J Stagg, Laura M Parkes, Stavros Stivaros, Nils Muhlert, Shruti Garg

{"title":"Neuroanatomical correlates of working memory performance in Neurofibromatosis 1.","authors":"Cameron Sawyer, Jonathan Green, Ben Lim, Gorana Pobric, JeYoung Jung, Grace Vassallo, D Gareth Evans, Charlotte J Stagg, Laura M Parkes, Stavros Stivaros, Nils Muhlert, Shruti Garg","doi":"10.1093/texcom/tgac021","DOIUrl":"10.1093/texcom/tgac021","url":null,"abstract":"Introduction: Neurofibromatosis 1 (NF1) is a single-gene disorder associated with cognitive impairments, particularly with deficits in working memory. Prior research indicates that brain structure is affected in NF1, but it is unclear how these changes relate to aspects of cognition.Methods: 29 adolescents aged 11-17 years were compared to age and sex-matched controls. NF1 subjects were assessed using detailed multimodal measurements of working memory at baseline followed by a 3T MR scan. A voxel-based morphometry approach was used to estimate the total and regional gray matter(GM) volumetric differences between the NF1 and control groups. The working memory metrics were subjected to a principal component analysis (PCA) approach.Results: The NF1 groups showed increased gray matter volumes in the thalamus, corpus striatum, dorsal midbrain and cerebellum bilaterally in the NF1 group as compared to controls. Principal component analysis on the working memory metrics in the NF1 group yielded three independent factors reflecting high memory load, low memory load and auditory working memory. Correlation analyses revealed that increased volume of posterior cingulate cortex, a key component of the default mode network (DMN) was significantly associated with poorer performance on low working memory load tasks.Conclusion: These results are consistent with prior work showing larger subcortical brain volumes in the NF1 cohort. The strong association between posterior cingulate cortex volume and performance on low memory load conditions supports hypotheses of deficient DMN structural development, which in turn may contribute to the cognitive impairments in NF1.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgac021"},"PeriodicalIF":0.0,"publicationDate":"2022-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47453576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Boosting working memory: uncovering the differential effects of tDCS and tACS 促进工作记忆:揭示tDCS和tACS的不同作用

Cerebral cortex communications Pub Date : 2022-05-07 DOI: 10.1093/texcom/tgac018

D. Senkowski, Rabea Sobirey, D. Haslacher, S. Soekadar

{"title":"Boosting working memory: uncovering the differential effects of tDCS and tACS","authors":"D. Senkowski, Rabea Sobirey, D. Haslacher, S. Soekadar","doi":"10.1093/texcom/tgac018","DOIUrl":"https://doi.org/10.1093/texcom/tgac018","url":null,"abstract":"Abstract Working memory (WM) is essential for reasoning, decision-making, and problem solving. Recently, there has been an increasing effort in improving WM through noninvasive brain stimulation (NIBS), especially transcranial direct and alternating current stimulation (tDCS/tACS). Studies suggest that tDCS and tACS can modulate WM performance, but large variability in research approaches hinders the identification of optimal stimulation protocols and interpretation of study results. Moreover, it is unclear whether tDCS and tACS differentially affect WM. Here, we summarize and compare studies examining the effects of tDCS and tACS on WM performance in healthy adults. Following PRISMA-selection criteria, our systematic review resulted in 43 studies (29 tDCS, 11 tACS, 3 both) with a total of 1826 adult participants. For tDCS, only 4 out of 23 single-session studies reported effects on WM, while 7 out of 9 multi-session experiments showed positive effects on WM training. For tACS, 10 out of 14 studies demonstrated effects on WM, which were frequency dependent and robust for frontoparietal stimulation. Our review revealed no reliable effect of single-session tDCS on WM but moderate effects of multi-session tDCS and single-session tACS. We discuss the implications of these findings and future directions in the emerging research field of NIBS and WM.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46782141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Neural correlates of a load-dependent decline in visual working memory 视觉工作记忆负荷依赖性衰退的神经关联

Cerebral cortex communications Pub Date : 2022-04-09 DOI: 10.1093/texcom/tgac015

Yaju Li, Y. Noguchi

引用次数: 1

Neural correlates with individual differences in temporal prediction during auditory-motor synchronization 听觉运动同步过程中时间预测的神经相关性与个体差异

Cerebral cortex communications Pub Date : 2022-04-07 DOI: 10.1093/texcom/tgac014

Kohei Miyata, Tetsuya Yamamoto, M. Fukunaga, Sho K. Sugawara, N. Sadato

{"title":"Neural correlates with individual differences in temporal prediction during auditory-motor synchronization","authors":"Kohei Miyata, Tetsuya Yamamoto, M. Fukunaga, Sho K. Sugawara, N. Sadato","doi":"10.1093/texcom/tgac014","DOIUrl":"https://doi.org/10.1093/texcom/tgac014","url":null,"abstract":"Abstract Temporal prediction ability is vital for movement synchronization with external rhythmic stimuli (sensorimotor synchronization); however, little is known regarding individual variations in temporal prediction ability and its neural correlates. We determined the underlying neural correlates of temporal prediction and individual variations during auditory-motor synchronization. We hypothesized that the non-primary motor cortices, such as the premotor cortex and supplementary motor area, are the key brain regions that correlate individual variations in prediction ability. Functional magnetic resonance imaging (7T) was performed for 18 healthy volunteers who tapped to 3 types of auditory metronome beats: isochronous, tempo change, and random. The prediction ability was evaluated using prediction/tracking ratios that were computed based on cross-correlations between tap timing and pacing events. Participants with a higher prediction/tracking ratio (i.e. stronger predictive tendency) tapped to metronome beats more accurately and precisely. The prediction/tracking ratio was positively correlated with the activity in the bilateral dorsal premotor cortex (PMd), suggesting that the bilateral PMd explains the individual variation in prediction ability. These results indicate that the PMd is involved in generating a model for temporal prediction of auditory rhythm patterns and its activity would reflect model accuracy, which is critical for accurate and precise sensorimotor synchronization.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45281296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Benefit from retrieval practice is linked to temporal and frontal activity in healthy young and older humans. 检索实践的益处与健康的年轻人和老年人的颞叶和额叶活动有关

Cerebral cortex communications Pub Date : 2022-02-17 eCollection Date: 2022-01-01 DOI: 10.1093/texcom/tgac009

Catherine-Noémie Alexandrina Guran, Lorena Deuker, Martin Göttlich, Nikolai Axmacher, Nico Bunzeck

{"title":"Benefit from retrieval practice is linked to temporal and frontal activity in healthy young and older humans.","authors":"Catherine-Noémie Alexandrina Guran, Lorena Deuker, Martin Göttlich, Nikolai Axmacher, Nico Bunzeck","doi":"10.1093/texcom/tgac009","DOIUrl":"10.1093/texcom/tgac009","url":null,"abstract":"Retrieval practice improves retention of information in long-term memory more than restudy, but the underlying neural mechanisms of this \"retrieval practice effect\" (RPE) remain poorly understood. Therefore, we investigated the behavioral and neural differences between previously retrieved versus restudied items at final retrieval. Thirty younger (20-30 years old) and twenty-five older (50+ years old) adults learned familiar and new picture stimuli either through retrieval or restudy. At final recognition, hemodynamic activity was measured using functional magnetic resonance imaging (fMRI). Behaviorally, younger and older adults showed similar benefits of retrieval practice, with higher recollection, but unchanged familiarity rates. In a univariate analysis of the fMRI data, activation in medial prefrontal cortex and left temporal regions correlated with an individual's amount of behavioral benefit from retrieval practice, irrespective of age. Compatible with this observation, in a multivariate representational similarity analysis (RSA), retrieval practice led to an increase in pattern similarity for retested items in a priori defined regions of interest, including the medial temporal lobe, as well as prefrontal and parietal cortex. Our findings demonstrate that retrieval practice leads to enhanced long-term memories in younger and older adults alike, and this effect may be driven by fast consolidation processes.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgac009"},"PeriodicalIF":0.0,"publicationDate":"2022-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44465939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Individual cerebrocerebellar functional network analysis decoding symptomatologic dynamics of postoperative cerebellar mutism syndrome 个体脑脊髓功能网络分析解码术后小脑缄默症综合征的症状动力学

Cerebral cortex communications Pub Date : 2022-02-11 DOI: 10.1093/texcom/tgac008

Ko-Ting Chen, T. Ho, T. Siow, Yu-Chiang Yeh, Sheng-Yao Huang

{"title":"Individual cerebrocerebellar functional network analysis decoding symptomatologic dynamics of postoperative cerebellar mutism syndrome","authors":"Ko-Ting Chen, T. Ho, T. Siow, Yu-Chiang Yeh, Sheng-Yao Huang","doi":"10.1093/texcom/tgac008","DOIUrl":"https://doi.org/10.1093/texcom/tgac008","url":null,"abstract":"Abstract Introduction Postoperative cerebellar mutism syndrome (pCMS) consists of three types of symptoms (motoric, linguistic, and neurobehavioral) in patients with posterior fossa pathologies. The evolutional mechanism of this high cognitive syndromic complex from cerebellar origin remains unconfirmed. Previous studies analyzing CMS patients mostly focused on the association between structural abnormalities that occur during CMS, of which proximal efferent cerebellar pathway (pECP) injury appears to be the most common pathogenesis. However, structural imaging may not be sensitive enough to determine the dynamic course of CMS, since the symptomatology is primarily an output of cerebral operation. Method We took a network approach in a child during her course of development and recovery of the pCMS. On the other hand, a network neuroscience approach using a mathematical model to extract information from functional imaging to generate interregional connectivity provides abundant evidence that the cerebellum is influential in modulating cerebral functions. Result This study applied a network approach to children with pCMS. An individual cerebrocerebellar functional network analysis using graph theory was then performed to determine the network dynamics during CMS. Cross-validation of clinical neurophysiology and functional neuroscience suggested the critical role of the pECP within CMS from the network analysis. Conclusion The employed approach was therefore useful in determining the complex clinical symptoms using individual functional network analysis, which bridges the gap between structural neuroimaging and clinical neurophysiology.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47922309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Visual attention around a hand location localized by proprioceptive information 视觉注意周围的手定位的本体感觉信息

Cerebral cortex communications Pub Date : 2022-02-07 DOI: 10.1093/texcom/tgac005

S. Shioiri, Takumi Sasada, Ryota Nishikawa

{"title":"Visual attention around a hand location localized by proprioceptive information","authors":"S. Shioiri, Takumi Sasada, Ryota Nishikawa","doi":"10.1093/texcom/tgac005","DOIUrl":"https://doi.org/10.1093/texcom/tgac005","url":null,"abstract":"Abstract Facilitation of visual processing has been reported in the space near the hand. To understand the underlying mechanism of hand proximity attention, we conducted experiments that isolated hand-related effects from top–down attention, proprioceptive information from visual information, the position effect from the influence of action, and the distance effect from the peripersonal effect. The flash-lag effect was used as an index of attentional modulation. Because the results showed that the flash-lag effect was smaller at locations near the hand, we concluded that there was a facilitation effect of the visual stimuli around the hand location identified through proprioceptive information. This was confirmed by conventional reaction time measures. We also measured steady-state visual evoked potential (SSVEP) in order to investigate the spatial properties of hand proximity attention and top–down attention. The results showed that SSVEP reflects the effect of top–down attention but not that of hand proximity attention. This suggests that the site of hand proximity attention is at a later stage of visual processing, assuming that SSVEP responds to neural activities at the early stages. The results of left-handers differed from those of right-handers, and this is discussed in relation to handedness variation.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61090302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Maturity of white matter tracts is associated with episodic memory recall during development 发育过程中白质束的成熟与情景记忆的回忆有关

Cerebral cortex communications Pub Date : 2022-01-27 DOI: 10.1093/texcom/tgac004

Antoine Bouyeure, D. Bekha, Sandesh Patil, L. Hertz-Pannier, M. Noulhiane

{"title":"Maturity of white matter tracts is associated with episodic memory recall during development","authors":"Antoine Bouyeure, D. Bekha, Sandesh Patil, L. Hertz-Pannier, M. Noulhiane","doi":"10.1093/texcom/tgac004","DOIUrl":"https://doi.org/10.1093/texcom/tgac004","url":null,"abstract":"Abstract The structure-function relationship between white matter microstructure and episodic memory (EM) has been poorly studied in the developing brain, particularly in early childhood. Previous studies in adolescents and adults have shown that episodic memory recall is associated with prefrontal-limbic white matter microstructure. It is unknown whether this association is also observed during early ontogeny. Here, we investigated the association between prefrontal-limbic tract microstructure and EM performance in a cross-sectional sample of children aged 4 to 12 years. We used a multivariate partial least squares correlation approach to extract tract-specific latent variables representing shared information between age and diffusion parameters describing tract microstructure. Individual projections onto these latent variables describe patterns of interindividual differences in tract maturation that can be interpreted as scores of white matter tract microstructural maturity. Using these estimates of microstructural maturity, we showed that maturity scores of the uncinate fasciculus and dorsal cingulum bundle correlated with distinct measures of EM recall. Furthermore, the association between tract maturity scores and EM recall was comparable between younger and older children. Our results provide new evidence on the relation between white matter maturity and EM performance during development.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47761180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Anodal tDCS over the medial prefrontal cortex enhances behavioral adaptation after punishments during reversal learning through increased updating of unchosen choice options 内侧前额叶皮层的Anodal tDCS通过增加未选择选项的更新，增强了逆转学习中惩罚后的行为适应

Cerebral cortex communications Pub Date : 2022-01-27 DOI: 10.1093/texcom/tgac006

Martin Panitz, L. Deserno, E. Kaminski, A. Villringer, B. Sehm, F. Schlagenhauf

{"title":"Anodal tDCS over the medial prefrontal cortex enhances behavioral adaptation after punishments during reversal learning through increased updating of unchosen choice options","authors":"Martin Panitz, L. Deserno, E. Kaminski, A. Villringer, B. Sehm, F. Schlagenhauf","doi":"10.1093/texcom/tgac006","DOIUrl":"https://doi.org/10.1093/texcom/tgac006","url":null,"abstract":"Abstract The medial prefrontal cortex (mPFC) is thought to be central for flexible behavioral adaptation. However, the causal relationship between mPFC activity and this behavior is incompletely understood. We investigated whether transcranial direct current stimulation (tDCS) over the mPFC alters flexible behavioral adaptation during reward-based decision-making, targeting Montreal Neurological Institute (MNI) coordinates X = −8, Y = 62, Z = 12, which has previously been associated with impaired behavioral adaptation in alcohol-dependent patients. Healthy human participants (n = 61) received either anodal (n = 30) or cathodal (n = 31) tDCS versus sham tDCS while performing a reversal learning task. To assess the mechanisms of reinforcement learning (RL) underlying our behavioral observations, we applied computational models that varied with respect to the updating of the unchosen choice option. We observed that anodal stimulation over the mPFC induced increased choice switching after punishments compared with sham stimulation, whereas cathodal stimulation showed no effect on participants’ behavior compared with sham stimulation. RL revealed increased updating of the unchosen choice option under anodal as compared with sham stimulation, which accounted well for the increased tendency to switch after punishments. Our findings provide a potential model for tDCS interventions in conditions related to flexible behavioral adaptation, such as addiction.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45336385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Brain reactivity to emotion persists in NREM sleep and is associated with individual dream recall. 大脑对情绪的反应在 NREM 睡眠中持续存在，并与个人的梦境回忆有关。

Cerebral cortex communications Pub Date : 2022-01-27 eCollection Date: 2022-01-01 DOI: 10.1093/texcom/tgac003

Maëva Moyne, Guillaume Legendre, Luc Arnal, Samika Kumar, Virginie Sterpenich, Margitta Seeck, Didier Grandjean, Sophie Schwartz, Patrik Vuilleumier, Judith Domínguez-Borràs

{"title":"Brain reactivity to emotion persists in NREM sleep and is associated with individual dream recall.","authors":"Maëva Moyne, Guillaume Legendre, Luc Arnal, Samika Kumar, Virginie Sterpenich, Margitta Seeck, Didier Grandjean, Sophie Schwartz, Patrik Vuilleumier, Judith Domínguez-Borràs","doi":"10.1093/texcom/tgac003","DOIUrl":"10.1093/texcom/tgac003","url":null,"abstract":"The waking brain efficiently detects emotional signals to promote survival. However, emotion detection during sleep is poorly understood and may be influenced by individual sleep characteristics or neural reactivity. Notably, dream recall frequency has been associated with stimulus reactivity during sleep, with enhanced stimulus-driven responses in high vs. low recallers. Using electroencephalography (EEG), we characterized the neural responses of healthy individuals to emotional, neutral voices, and control stimuli, both during wakefulness and NREM sleep. Then, we tested how these responses varied with individual dream recall frequency. Event-related potentials (ERPs) differed for emotional vs. neutral voices, both in wakefulness and NREM. Likewise, EEG arousals (sleep perturbations) increased selectively after the emotional voices, indicating emotion reactivity. Interestingly, sleep ERP amplitude and arousals after emotional voices increased linearly with participants' dream recall frequency. Similar correlations with dream recall were observed for beta and sigma responses, but not for theta. In contrast, dream recall correlations were absent for neutral or control stimuli. Our results reveal that brain reactivity to affective salience is preserved during NREM and is selectively associated to individual memory for dreams. Our findings also suggest that emotion-specific reactivity during sleep, and not generalized alertness, may contribute to the encoding/retrieval of dreams.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgac003"},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39638543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0