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Cancer chemotherapy and biological response modifiers最新文献

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Breast cancer. 乳腺癌。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21028-0
Pinuccia Valagussa, Gianni Bonadonna
{"title":"Breast cancer.","authors":"Pinuccia Valagussa, Gianni Bonadonna","doi":"10.1016/s0921-4410(03)21028-0","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21028-0","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"585-608"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined modality therapy for rectal cancer. 直肠癌的综合治疗。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21038-3
Bruce D Minsky
{"title":"Combined modality therapy for rectal cancer.","authors":"Bruce D Minsky","doi":"10.1016/s0921-4410(03)21038-3","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21038-3","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"803-16"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Melanoma--new developments in diagnosis and therapy. 黑色素瘤——诊断和治疗的新进展。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01
A Schneeberger, S N Wagner
{"title":"Melanoma--new developments in diagnosis and therapy.","authors":"A Schneeberger, S N Wagner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"609-36"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk assessment and screening for colorectal cancer. 结直肠癌的风险评估和筛查。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21035-8
Karen E Kim
{"title":"Risk assessment and screening for colorectal cancer.","authors":"Karen E Kim","doi":"10.1016/s0921-4410(03)21035-8","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21035-8","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"747-57"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-carcinoembryonic antigen immunity. 抗癌胚胎抗原免疫。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21015-2
Mark DeBenedette, Laszlo Radvanyi, Devender Singh-Sandhu, Neil L Berinstein
{"title":"Anti-carcinoembryonic antigen immunity.","authors":"Mark DeBenedette, Laszlo Radvanyi, Devender Singh-Sandhu, Neil L Berinstein","doi":"10.1016/s0921-4410(03)21015-2","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21015-2","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"299-325"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thymidylate synthase inhibitors. 胸腺苷酸合成酶抑制剂。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21001-2
Stephen P Ackland, Phillip Beale, Godefridus J Peters
{"title":"Thymidylate synthase inhibitors.","authors":"Stephen P Ackland, Phillip Beale, Godefridus J Peters","doi":"10.1016/s0921-4410(03)21001-2","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21001-2","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24661160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sarcoma. 肉瘤。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21030-9
Michelle Scurr, Ian Judson
{"title":"Sarcoma.","authors":"Michelle Scurr, Ian Judson","doi":"10.1016/s0921-4410(03)21030-9","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21030-9","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"637-53"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24660541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyclin-dependent kinases as targets for cancer therapy. 细胞周期蛋白依赖激酶作为癌症治疗的靶点。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21007-3
Manish A Shah, Gary K Schwartz
{"title":"Cyclin-dependent kinases as targets for cancer therapy.","authors":"Manish A Shah,&nbsp;Gary K Schwartz","doi":"10.1016/s0921-4410(03)21007-3","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21007-3","url":null,"abstract":"<p><p>Cell cycle perturbations are commonly observed in human malignancies. Exploiting this finding is the rationale for the development of CDK inhibitors as anti-tumor agents. Single-agent evaluation of several CDKIs has demonstrated limited clinical activity. The combination of CDKIs with standard cytotoxic agents is an emerging, alternative approach to anticancer therapy that also exploits the cell cycle perturbations of malignancy. Pre-clinical studies demonstrate the concept of cell cycle mediated drug resistance, and suggest that the combination of standard cytotoxic agents with CDKIs will require thoughtful sequencing and scheduling. With this in mind, there are presently several clinical investigations underway examining the combination of a standard cytotoxic with a novel CDKI, with particular attention to sequence and scheduling. Although phase II evaluation of these combination studies will provide initial evidence of anti-tumor activity, definitive phase III studies will be needed to establish this class of agents in the care of patients with cancer.</p>","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"145-70"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24661166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Melanoma--new developments in diagnosis and therapy. 黑色素瘤——诊断和治疗的新进展。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01 DOI: 10.1016/s0921-4410(03)21029-2
A. Schneeberger, Wagner Sn
{"title":"Melanoma--new developments in diagnosis and therapy.","authors":"A. Schneeberger, Wagner Sn","doi":"10.1016/s0921-4410(03)21029-2","DOIUrl":"https://doi.org/10.1016/s0921-4410(03)21029-2","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 1","pages":"609-36"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56279711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthracyclines. 蒽环霉素。
Cancer chemotherapy and biological response modifiers Pub Date : 2003-01-01
Luca Gianni, Giacomo Grasselli, Sara Cresta, Alberta Locatelli, Lucia Viganò, Giorgio Minotti
{"title":"Anthracyclines.","authors":"Luca Gianni,&nbsp;Giacomo Grasselli,&nbsp;Sara Cresta,&nbsp;Alberta Locatelli,&nbsp;Lucia Viganò,&nbsp;Giorgio Minotti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72508,"journal":{"name":"Cancer chemotherapy and biological response modifiers","volume":"21 ","pages":"29-40"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24661161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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