Advances in Bioengineering最新文献_第8页

A Structural Constitutive Model for Planar Collagenous Tissues That Integrates SALS-Derived Fiber Orientation Data 平面胶原组织的结构本构模型，整合了sals衍生的纤维取向数据

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23065

M. Sacks

引用次数: 4

Flow Evaluation of a Compliant Coronary Artery Anastomosis Model 顺应性冠状动脉吻合模型的血流评价

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23123

Pedro D. Pedroso, R. Venugopalan, A. Anayiotos

{"title":"Flow Evaluation of a Compliant Coronary Artery Anastomosis Model","authors":"Pedro D. Pedroso, R. Venugopalan, A. Anayiotos","doi":"10.1115/imece2001/bed-23123","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23123","url":null,"abstract":"\u0000 Coronary artery bypass grafting (CABG) is a common surgical procedure for coronary artery diseases or severe stenosis of the coronary arteries. It makes use of a peripheral vein (usually the saphenous vein of the leg) to form a conduit between the aorta and the coronary artery distal to the obstructive lesion. It is rapidly becoming the treatment of choice in cases where the vessel is more than 70% occluded or when angioplasty is not possible. However, a significant number of grafts subsequently fail due to acute thrombosis in the early post-operative period or to restenosis within months or years. Intimal thickening in the CABG anastomosis has been implicated as the major cause of restenosis and long-term graft failure. Several studies point to the interplay between non-uniform hemodynamics (including disturbed flows and recirculation zones), wall shear stress, and long particle residence time as possible etiologies. An important feature of the anastomosis geometry, is a bulge that forms at the veno-arterial junction. This sinus forms as a result of the stretching of the thin venous wall when the graft is exposed to aortic pressure conditions. The resultant sinus, and the impedance mismatch of the vein-artery connection, contribute to a complicated region of highly disturbed flow at the divider and may have a primary role in restenosis and final failure of the graft.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85169728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Material Model for Shortening-Dependent Stiffness of Tracheal Smooth Muscle 气管平滑肌缩短相关刚度的材料模型

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23161

P. A. Sarma, R. Pidaparti, R. Meiss

引用次数: 1

Relationships Between Transfemoral Socket Interface Pressure and Hip Moment of Residual Limb With a 4-Bar Pneumatic Knee During Stance Phase of Gait 步态站立阶段4-Bar气动膝关节残肢髋关节力矩与经股窝界面压力的关系

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23051

Junghwa Hong, J. Ryu, Shin-Ki Kim, M. Mun

引用次数: 0

Shape Opimization of Femoral Components of an Artificial Hip Prosthesis Using the Three-Dimensional P-Version Finite Element Method 三维p型有限元法优化人工髋关节假体股骨假体的形状

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23012

M. Higa, I. Nishimura, H. Tanino, Y. Mitamura

引用次数: 0

Numerical Simulation and Evaluation of the Reduced-Platen Compression Test for Estimating Cancellous Bone Mechanical Properties in the Rat 估计大鼠松质骨力学性能的减压试验数值模拟与评价

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23030

H. Hogan, Kent D. Harms, H. Sampson

{"title":"Numerical Simulation and Evaluation of the Reduced-Platen Compression Test for Estimating Cancellous Bone Mechanical Properties in the Rat","authors":"H. Hogan, Kent D. Harms, H. Sampson","doi":"10.1115/imece2001/bed-23030","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23030","url":null,"abstract":"\u0000 Animal models are utilized in numerous research studies aimed at better understanding skeletal biology, bone biomechanics, and many orthopedic diseases or pathologies. Prominent among these animal models are rodents, most commonly rats and mice. In estimating bone mechanical properties in these animals, cortical bone is routinely assessed by bending one of the long bones such as the femur or tibia, which targets the mid-diaphysis region. Testing specimens of isolated cancellous bone is exceedingly challenging, however, even for the larger rat skeleton. Recognizing the prominence and importance of cancellous bone mechanical properties has led to increased mechanical testing of vertebra and femoral neck specimens in skeletal research employing rats and mice. The specimens in these tests actually consist of a combination of both cortical and cancellous tissue, however. In an attempt to more closely approximate the ideal of isolated cancellous bone specimens a method has been developed recently for testing specimens from the proximal tibia metaphysis and distal femoral metaphysis [1]. In either case, the specimen in this so-called “reduced-platen compression” (RPC) test consists of a section of the metaphysis containing both cortical and cancellous bone. The specimen and test configuration are illustrated schematically in Fig. 1.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81059685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Agarose and Alginate Gels for Cell Compression Experiments 琼脂糖和海藻酸盐凝胶在细胞压缩实验中的表征

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23143

J. Srinivasan, N. Mukherjee

{"title":"Characterization of Agarose and Alginate Gels for Cell Compression Experiments","authors":"J. Srinivasan, N. Mukherjee","doi":"10.1115/imece2001/bed-23143","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23143","url":null,"abstract":"\u0000 Various concentrations of folly hydrated agarose and alginate gel formed into cuboid shapes are tested in unconfined compression with impermeable plattens to determine Young’s modulus at equilibrium (relaxed elastic modulus) of the gel blocks. Repeat testing of a single block was performed to assess intra-test variability in testing conditions and deterioration of the gels during the testing procedure. Variability in material properties of gels formed in a single batch was assessed. The data was compared with values obtained from a search of relevant literature. While general trends in the data were the same (increased modulus for larger concentration gel), large differences in actual values of material properties were noted which could be ascribed to differences in the method and conditions of testing and theoretical models used to obtain material properties. Accurate properties of the gels are needed in gel-cell (cells embedded in gel) compression experiments in order to extract accurate cellular properties. It is concluded that it is necessary to use the gel material properties obtained under the same conditions of testing in order to determine cellular material properties in gel-cell compression experiments.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81280454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved Histologic Analysis of Component Distribution and Wall Behavior in Cyanoacrylate-Embolized Vessels 氰基丙烯酸酯栓塞血管中成分分布和管壁行为的改进组织学分析

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23131

W. Calvo, B. Lieber, A. Wakhloo, L. Hopkins

引用次数: 0

The Role of Biomechanics in the Modern Biomedical Engineering Undergraduate Curriculum 生物力学在现代生物医学工程本科课程中的作用

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23023

R. Spilker, R. Kamm

{"title":"The Role of Biomechanics in the Modern Biomedical Engineering Undergraduate Curriculum","authors":"R. Spilker, R. Kamm","doi":"10.1115/imece2001/bed-23023","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23023","url":null,"abstract":"\u0000 During the Summer and Fall of 2000, the Whitaker Foundation engaged the biomedical engineering community in a curriculum assessment and vision exercise that included: collection and posting (www.Whitaker.org) of a curriculum database from departments and programs in bioengineering (note that within this document, bioengineering is understood to be synonymous with biomedical engineering); identification of key curricular topic areas and facilitators for each of these areas; posting of white papers by the facilitators; and a period of community comment. This activity culminated in the Whitaker Educational Summit, held in December 2000, at which representatives of virtually all US bioengineering departments and programs, numerous international participants, and those interested in establishing programs, gathered for a series of lectures and discussions on general topics in the undergraduate bioengineering curriculum, and for focused group discussions in each of the topic areas. Summary comments were prepared at that meeting by professional science writers and published at the Whitaker web site, and a period of comment followed. As facilitators for the area of biomechanics, and representatives of the US National Committee on Biomechanics, we offer a vision of biomechanics in the undergraduate bioengineering curriculum, and a set of recommendations that result from the. Whitaker process.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82980532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Device for Driving a Wire or a Drill Precisely in a Given Direction Through a Point Under Closed Sky Conditions 在封闭的天空条件下，沿着给定的方向精确地穿过一点的一种装置

Advances in Bioengineering Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23079

G. Danieli, G. Fragomeni, E. Giuzio

{"title":"A Device for Driving a Wire or a Drill Precisely in a Given Direction Through a Point Under Closed Sky Conditions","authors":"G. Danieli, G. Fragomeni, E. Giuzio","doi":"10.1115/imece2001/bed-23079","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23079","url":null,"abstract":"\u0000 The paper presents a new device which allows the precise positioning of a guide through a point and in a given direction, or which can permit to reach a given bone section. Other devices exist mainly addressed to the insertion of a screw in the correct position on endo-medullary nails, but these are usually based on the knowledge of the geometry of the nail, and are therefore made by the maker of the nail. In other instances, often the doctors use trial drilling under fluoroscopy to place a kirshner wire in the required position. The actual device is instead based only on an aiming methodology resting on geometrical considerations. Previous knowledge of the position of such a point and direction, which can be given by a hole belonging to a plate or to an endo-medullary nail or can be part of the patient’s bone structure, is not necessary. This is due to the use of fluoroscopy coupled to the localisation of two aiming planes on whose interception is placed the line of interest. A first instrument developed on this principle found limited clinical success due to the complexity of the first kinematic chain used in the aiming process and to human error. A new version has been designed and is at present under construction, which solves the kinematic problem through a careful choice of a series of constraints enabling the aiming process to be divided in sub processes, thus gradually controlling the final result.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89770909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0