Santiago Alba-Valencia, Liliana Estefania Ramos-Villalobos, Briana Ángeles Díaz-Herrera, Diego Araiza-Garaygordobil
{"title":"Acute myocardial infarction in the setting of anomalous single coronary artery.","authors":"Santiago Alba-Valencia, Liliana Estefania Ramos-Villalobos, Briana Ángeles Díaz-Herrera, Diego Araiza-Garaygordobil","doi":"10.47487/apcyccv.v7i1.574.","DOIUrl":"10.47487/apcyccv.v7i1.574.","url":null,"abstract":"","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"86-88"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Chacón-Díaz, Marco Antonio Lazo Soldevilla, Aníbal Díaz-Lazo, Ofelia Araoz Tarco, Ana C Gonzales-Luna, Carlos Rubén Barrientos, Fernando Gamio Vega Centeno, Sofía Robles Cabellos, Jorge Luis Sotomayor-Perales
{"title":"The cardiovascular system and high-altitude exposure: from adaptation to disease. Part I.","authors":"Manuel Chacón-Díaz, Marco Antonio Lazo Soldevilla, Aníbal Díaz-Lazo, Ofelia Araoz Tarco, Ana C Gonzales-Luna, Carlos Rubén Barrientos, Fernando Gamio Vega Centeno, Sofía Robles Cabellos, Jorge Luis Sotomayor-Perales","doi":"10.47487/apcyccv.v7i1.564.","DOIUrl":"10.47487/apcyccv.v7i1.564.","url":null,"abstract":"<p><p>Exposure to high altitude constitutes a complex physiological challenge, driven primarily by hypobaric hypoxia and, in some settings, by extreme environmental conditions such as severe cold and increased ultraviolet radiation. At the cardiovascular level, this exposure elicits a range of acute and chronic adaptations, including activation of the sympathetic nervous system, pulmonary vasoconstriction, and vascular and ventricular remodelling. In the Andean region, millions of people live at elevations above 2,500 metres above sea level, rendering them particularly susceptible to these physiological adaptations and the associated cardiovascular alterations. This manuscript represents the first part of a narrative review and aims to synthesise the available scientific evidence on mechanisms of adaptation to high altitude, as well as the characteristics of pulmonary hypertension, heart failure, and congenital heart disease observed in both native high-altitude populations and individuals originating from low-altitude areas. In addition, it seeks to identify existing gaps in current knowledge of these conditions in order to promote the development of specific diagnostic, preventive, and therapeutic strategies aimed at improving cardiovascular health among populations residing at or temporarily exposed to high altitude.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"52-60"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arturo Miguel Cagide, Ignacio Martín Bluro, Aníbal Martín Arias, María Natalia Pellegrini, Juan María Iroulart
{"title":"Mixed shock: from pathophysiology to clinical practice.","authors":"Arturo Miguel Cagide, Ignacio Martín Bluro, Aníbal Martín Arias, María Natalia Pellegrini, Juan María Iroulart","doi":"10.47487/apcyccv.v7i1.567","DOIUrl":"10.47487/apcyccv.v7i1.567","url":null,"abstract":"<p><p>Mixed shock represents a complex haemodynamic entity arising from a variable combination of impaired contractility and vasoplegia. Its clinical recognition is challenging, as it may appear as an intermediate state in the evolution of cardiogenic or distributive shock, or result from the simultaneous coexistence of distinct pathophysiological mechanisms. Neurohormonal activation, which is common across both ends of the shock spectrum, contributes to fluid retention and further deterioration of circulatory function. Although pathophysiological interpretation is essential to guide management, it may be constrained by the temporal overlap of haemodynamic events. In clinical practice, the optimal approach integrates goal-directed haemodynamic correction with continuous bedside assessment of tissue perfusion. Pharmacological selection should account for the interaction between myocardial contractility and vascular tone, prioritising agents with combined or complementary effects. In this context, clinical judgement grounded in a sound understanding of pathophysiology remains the decisive tool in the management of mixed shock.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"46-51"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edgar Quispe-Silvestre, Karen Valeria Gamonal-Moran, Laura Cristina Dragonetti, Nicolás Almeida Arostegui
{"title":"Cardiac magnetic resonance parameters associated with myocarditis in patients treated with immunotherapy: a scoping review.","authors":"Edgar Quispe-Silvestre, Karen Valeria Gamonal-Moran, Laura Cristina Dragonetti, Nicolás Almeida Arostegui","doi":"10.47487/apcyccv.v7i1.586.","DOIUrl":"10.47487/apcyccv.v7i1.586.","url":null,"abstract":"<p><p>This scoping review, conducted in accordance with the PRISMA-ScR methodology, maps the available scientific evidence on cardiac magnetic resonance (CMR) abnormalities associated with immune checkpoint inhibitor-induced myocarditis (ICI-M). Twenty studies published between 2019 and 2025 were analysed, highlighting alterations in left ventricular function (left ventricular ejection fraction [LVEF]), myocardial oedema detected by T2-weighted sequences, and fibrosis identified as late gadolinium enhancement (LGE). Key diagnostic criteria included elevated extracellular volume (ECV), impaired global longitudinal strain (GLS), and abnormal T1 and T2 relaxation times. Of the included studies, most were retrospective, followed by case reports and prospective studies. The therapies most frequently associated with ICI-M involved combinations of anti-PD1 and anti-CTLA4 agents. Cardiac magnetic resonance (CMR) has proven to be a highly sensitive, non-invasive tool for detecting myocardial involvement, even before the elevation of biomarkers such as troponins. The importance of using advanced tools like CMR to assess cardiovascular complications associated with myocarditis is highlighted. Parameters such as LVEF, GLS, LGE, and ECV provide valuable information on ventricular function and structural alterations related to myocarditis. These findings allow us to identify knowledge gaps and guide future research on the use of CMR in myocarditis.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"35-45"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of an educational program on adherence and quality of life in patients with heart failure.","authors":"Rosalynn Denisse Bazán Gallardo, Rolando Germán Gutiérrez Palomares, Mirian Marita Torres Grabiel, Betty Beatriz Lozada Arenas, Gaury Fabiola Quispe Peña","doi":"10.47487/apcyccv.v7i1.594.","DOIUrl":"10.47487/apcyccv.v7i1.594.","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effectiveness of an educational program on therapeutic adherence, quality of life, and satisfaction in heart failure patients treated at the nursing clinic.</p><p><strong>Materials and methods: </strong>A quasi-experimental, longitudinal, and prospective study was conducted with 42 patients treated at the National Cardiovascular Institute (INCOR-EsSalud). The intervention included five in-person educational sessions. Therapeutic adherence was assessed using the Morisky-Green test, and quality of life was assessed using the Minnesota Living with Heart Failure Questionnaire (MLHFQ) before and after the intervention. Pre-post comparisons were performed using McNemar's test<b>.</b></p><p><strong>Results: </strong>. In 42 patients, adherence according to the Morisky-Green test was 47.6% at baseline (20/42) and 83.3% post-intervention (35/42) (McNemar p=0.001). In the paired matrix, 18 patients improved from non-adherent to adherent, and 3 improved from adherent to non-adherent. In the MLHFQ, the \"good\" category was 26.2% at baseline (11/42) and 69.1% post-intervention (29/42); the \"poor\" category decreased from 7.1% (3/42) to 0%. 100% reported high satisfaction.</p><p><strong>Conclusions: </strong>. The nurse-led educational program was associated with a significant improvement in therapeutic adherence and quality of life in patients with heart failure. Participants also reported high levels of satisfaction with the educational intervention and the care received. These findings suggest that the program is a viable and accepted strategy for strengthening self-care in this population.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Chacón-Díaz, Marco Antonio Lazo Soldevilla, Aníbal Díaz-Lazo, Ofelia Araoz Tarco, Ana C Gonzales-Luna, Carlos Rubén Barrientos, Fernando Gamio Vega Centeno, Sofía Robles Cabellos, Jorge Luis Sotomayor-Perales
{"title":"The cardiovascular system and high-altitude exposure: from adaptation to disease. Part II.","authors":"Manuel Chacón-Díaz, Marco Antonio Lazo Soldevilla, Aníbal Díaz-Lazo, Ofelia Araoz Tarco, Ana C Gonzales-Luna, Carlos Rubén Barrientos, Fernando Gamio Vega Centeno, Sofía Robles Cabellos, Jorge Luis Sotomayor-Perales","doi":"10.47487/apcyccv.v7i1.565","DOIUrl":"10.47487/apcyccv.v7i1.565","url":null,"abstract":"<p><p>In this second part of the narrative review on cardiovascular pathology at high altitude, the clinical and pathophysiological characteristics of acute and chronic coronary artery disease, cardiac arrhythmias, and arterial hypertension under conditions of hypobaric hypoxia are addressed. Finally, the main gaps in current knowledge and the opportunities for the development of research aimed at achieving a better understanding of these conditions in populations permanently residing at high altitude are highlighted.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"7 1","pages":"61-63"},"PeriodicalIF":0.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillermo Solórzano Suárez, Paola Morejón Barragán, José Miguel Jáuregui Solórzano, Mónica Gilbert Orús
{"title":"Gap between availability and utilization of cardiac donors: analysis of determining factors in Ecuador.","authors":"Guillermo Solórzano Suárez, Paola Morejón Barragán, José Miguel Jáuregui Solórzano, Mónica Gilbert Orús","doi":"10.47487/apcyccv.v6i4.530","DOIUrl":"10.47487/apcyccv.v6i4.530","url":null,"abstract":"<p><strong>Objectives: </strong>To analyse factors associated with the rejection of heart donor offers referred to Clínica Guayaquil and to compare these findings with national data from the Instituto Nacional de Donación y Trasplante de Órganos, Tejidos y Células, in order to identify trends influencing organ acceptance.</p><p><strong>Materials and methods: </strong>We conducted an observational, retrospective study of heart donor offers received between September 2021 and July 2025. Demographic, clinical, anthropometric, and logistical variables were extracted from the institutional database and the National Information System for Donation and Transplantation (SINIDOT). Reasons for organ rejection were classified into eight predefined categories. Univariate and multivariate analyses were performed to identify factors associated with donor acceptance or rejection.</p><p><strong>Results: </strong>A total of 196 heart donor offers were received, of which 75% were rejected. Accepted donor organs were from younger donors, were more frequently male, and had higher predicted heart mass (PHM). Traumatic brain injury was the leading cause of death (49.5%). The most common reasons for rejection were classification as a non-standard risk donor (39.5%), logistical constraints (30.6%), and blood group incompatibility (15.6%). In multivariate analyses, older donor age and origin outside Guayaquil were associated with higher rejection rates, whereas male sex and higher PHM were associated with increased acceptance. Logistical problems rose from 0% in 2021 to more than 40% in 2024-2025, largely driven by limited availability of air transport.</p><p><strong>Conclusions: </strong>The high rate of donor heart rejection reflects substantial underutilisation of potentially viable organs. Strengthening transport logistics and broadening donor acceptance criteria could increase graft utilisation, reduce waiting-list mortality, and improve the overall efficiency of national heart transplantation programmes.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"6 4","pages":"197-206"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12825442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José de Jesús Bohórquez-Rivero, Paula Andrea Parra-Sánchez, Angela María Roa-Bocanegra
{"title":"[In response to: The hospitalized patient with severe aortic stenosis].","authors":"José de Jesús Bohórquez-Rivero, Paula Andrea Parra-Sánchez, Angela María Roa-Bocanegra","doi":"10.47487/apcyccv.v6i4.566","DOIUrl":"10.47487/apcyccv.v6i4.566","url":null,"abstract":"","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"6 4","pages":"276-278"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christie Villasante-Villalta, Diego Davila-Flores, Renee Montesinos-Segura, Zoila Rodriguez-Urtega, Judith Miranda-Rojas, José Cornejo-Acevedo, Fernando Vargas Peláez, Fernando Chavarri-Velarde
{"title":"Severe left ventricular dilatation and mitral regurgitation secondary to ALCAPA in childhood: a case report.","authors":"Christie Villasante-Villalta, Diego Davila-Flores, Renee Montesinos-Segura, Zoila Rodriguez-Urtega, Judith Miranda-Rojas, José Cornejo-Acevedo, Fernando Vargas Peláez, Fernando Chavarri-Velarde","doi":"10.47487/apcyccv.v6i4.535","DOIUrl":"10.47487/apcyccv.v6i4.535","url":null,"abstract":"<p><p>Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital heart defect, with an estimated incidence of 1 in 300,000 live births and a mortality rate approaching 90% within the first year of life if left untreated. We present the case of a three-year-old boy with progressive dyspnea, paroxysmal tachycardia, and poor weight gain, initially diagnosed with severe left ventricular dilatation and severe mitral regurgitation. Transthoracic echocardiography and cardiac computed tomography angiography confirmed the diagnosis of ALCAPA. Surgical correction included left coronary artery reimplantation and mitral valve repair. The patient was discharged without complications. At a two-year follow-up, he remained asymptomatic, with preserved left ventricular function and mild mitral regurgitation. This case highlights the importance of advanced imaging in the diagnosis and the role of surgical intervention in improving outcomes in this potentially fatal condition.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"6 4","pages":"258-263"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12825439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and echocardiographic characteristics of adults with atrial septal aneurysm.","authors":"Alfonso L León-Burgos","doi":"10.47487/apcyccv.v6i4.541","DOIUrl":"10.47487/apcyccv.v6i4.541","url":null,"abstract":"<p><strong>Objective: </strong>To determine the prevalence and describe the clinical and echocardiographic characteristics of adults with atrial septal aneurysm (ASA).</p><p><strong>Materials and methods: </strong>A cross-sectional, descriptive study was conducted. The population consisted of patients diagnosed with ASA by transthoracic echocardiography.</p><p><strong>Results: </strong>The prevalence was 2%. The median age was 71 years, and females predominated (58.8%). ASA with right bulging represented 74.8%. The most frequent comorbidity was hypertension (64.1%). Atrial tachyarrhythmias were the most prevalent arrhythmias, and the most common valvular disease was mitral regurgitation (26.7%).</p><p><strong>Conclusions: </strong>The prevalence of ASA was similar to that reported in the literature; females predominated, the most prevalent comorbidity was hypertension, atrial tachyarrhythmias were the most frequent arrhythmias, ASA with right bulging was the most common, and mitral regurgitation was the most prevalent valvulopathy.</p>","PeriodicalId":72295,"journal":{"name":"Archivos Peruanos de cardiologia y cirugia cardiovascular","volume":"6 4","pages":"223-229"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12825440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}