Beatrice Leonardi MD , Morena Fasano PhD , Giuseppe Vicario MD , Anna D’Agostino MD , Grazia Bergameo MD , Ciro Balbo MD , Paolo Chiodini PhD , Gaetana Messina MD , Fortunato Ciardiello PhD , Alfonso Fiorelli PhD
{"title":"Is Airway Stent a Definitive Treatment for Management of Malignant Central Airway Obstruction?","authors":"Beatrice Leonardi MD , Morena Fasano PhD , Giuseppe Vicario MD , Anna D’Agostino MD , Grazia Bergameo MD , Ciro Balbo MD , Paolo Chiodini PhD , Gaetana Messina MD , Fortunato Ciardiello PhD , Alfonso Fiorelli PhD","doi":"10.1016/j.atssr.2025.12.013","DOIUrl":"10.1016/j.atssr.2025.12.013","url":null,"abstract":"<div><h3>Background</h3><div>Airway stents are a palliative treatment for malignant central airway obstruction (MCAO). Reopening airways improves symptoms so that patients can undergo additional treatments such as chemo/radiotherapy. Airway stents may be withdrawn in case of tumoral response to treatment. However, stent fracture and airway injury are some complications reported after stent removal. Herein, we evaluated the feasibility of stent removal after MCAO.</div></div><div><h3>Methods</h3><div>This was a retrospective study including consecutive patients treated with airway self-expandable metallic stent insertion and subsequent chemo/radiotherapy for MCAO between June 2018 and June 2024 at our institution. Patients were divided in 2 groups: stent removal group and control group. The decision of removing the airway stent was based on response to therapy.</div></div><div><h3>Results</h3><div>Of the 72 included patients, 14 underwent stent removal. The median interval between stent placement and removal was 6 months and no intra- or periprocedural complications were observed. In 3 cases, the stent was removed after dislocation consequent to the tumoral response. Stent removal was associated with significant reduction of bronchoaspiration, infection, and granulation tissue formation, in addition to an increased overall survival (<em>P</em> = .029) and a lower 90-day mortality (<em>P</em> = .05) due to the better response to the therapy.</div></div><div><h3>Conclusions</h3><div>Airway stent removal after chemo/radiotherapy is safe and feasible, and not associated with severe complications in expert hands. In case of significant reduction of the tumor, patients should be considered for stent removal to reduce complications related to the stent presence.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 401-406"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Pulmonary Airway Malformation Manifesting as a Massive Tumor in an Adult Patient","authors":"Yuuki Kou MD, Ryosuke Matsuda MD, Yuya Kogita MD, Yasushi Sakamaki MD, PhD","doi":"10.1016/j.atssr.2025.09.030","DOIUrl":"10.1016/j.atssr.2025.09.030","url":null,"abstract":"<div><div>A 52-year-old male patient presented to our hospital (Osaka International Medical and Science Center, Osaka, Japan) with an abnormally large shadow in the right lung lobe. An enhanced computed tomographic scan of the chest revealed a massive tumor with multiple clusters and niveau formation in the lower lobe of the right lung. He received a diagnosis of congenital pulmonary airway malformation with infection and subsequently underwent surgery. Nowadays, most congenital lung malformations are diagnosed during the early intrauterine period, thus making congenital pulmonary airway malformation in adult patients extremely rare. These patients may experience recurrent infections or have malignant tumors; therefore, surgical treatment should be considered regardless of the presence or absence of symptoms.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 420-422"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atharv Oak BS , Abdullah Arain MBBS , Uzma Rahman MD , Sumera I. Yilmaz MS , Jesse Suben MD , Ahmet Kilic MD
{"title":"Mitral Valve Lymphoma: An Unusual Cause of Embolic Strokes","authors":"Atharv Oak BS , Abdullah Arain MBBS , Uzma Rahman MD , Sumera I. Yilmaz MS , Jesse Suben MD , Ahmet Kilic MD","doi":"10.1016/j.atssr.2025.09.028","DOIUrl":"10.1016/j.atssr.2025.09.028","url":null,"abstract":"<div><div>An 80-year-old woman with a history of non-Hodgkin lymphoma and branch retinal artery occlusion presented with acute visual changes and received a diagnosis of multifocal embolic cerebral infarcts. Cardiac imaging revealed a mobile left atrial mass on the mitral valve. Surgical excision was undertaken because of the high risk of recurrent embolization and strokes. Histopathologic examination demonstrated chronic lymphocytic leukemia/small lymphocytic lymphoma within a fibrinous and calcified matrix. This case illustrates a rare intracardiac manifestation of lymphoma serving as a cardioembolic source and highlights the importance of considering hematologic malignant disease in the differential diagnosis of intracardiac masses.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 635-637"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Outcomes of First-Time and Redo Mitral Valve Replacement Using MITRIS RESILIA Bioprosthesis","authors":"Satoshi Kainuma MD, PhD , Tomoki Shimokawa MD, PhD , Tomohiro Iwakura MD, PhD , Haruki Mikoshiba MD , Atsushi Yano MD , Atsushi Kurushima MD , Tatsuo Motoki MD , Yoshiaki Fukumura MD , Kazuhisa Sakamoto MD , Yuki Wada MD , Nobuhisa Ohno MD, PhD , Tomoki Ushijima MD, PhD , Akira Shiose MD, PhD , Katsuhiro Omae PhD , Manabu Minami MD, PhD , Haruko Yamamoto MD, PhD , Rieko Kutsuzawa MD , Shinya Tajima MD , Tomoyuki Fujita MD, PhD , Satsuki Fukushima MD, PhD","doi":"10.1016/j.atssr.2025.12.015","DOIUrl":"10.1016/j.atssr.2025.12.015","url":null,"abstract":"<div><h3>Background</h3><div>The MITRIS RESILIA bioprosthetic valve incorporates anticalcification technology and is designed to facilitate implantation in fragile mitral annuli. However, clinical data on its safety and hemodynamic performance remain limited.</div></div><div><h3>Methods</h3><div>We conducted a retrospective multicenter study of 140 patients (mean age, 75 ± 8 years; 44% male) who underwent first-time (n = 100) or redo (n = 40) mitral valve replacement (MVR) with a MITRIS RESILIA valve between 2021 and 2022. The primary indication for first-time MVR was mitral regurgitation, followed by mitral stenosis, whereas that for redo MVR was prosthetic valve dysfunction, followed by failed repair. The mean follow-up duration was 36 ± 14 months (415 patient-years).</div></div><div><h3>Results</h3><div>The most frequently implanted valve size was 27 mm (31%), followed by 29 mm (26%) and 25 mm (24%). Thirty-day mortality was 2.0% for first-time MVR patients and 0% for redo patients. At 3 years, freedom from all-cause mortality, reoperation, stroke, and structural valve deterioration was 89%, 99%, 96%, and 100%, respectively, with no intergroup differences. The mixed effects model found stable and favorable prosthetic hemodynamics over time—reflected by mean pressure gradients, effective orifice area, and the absence of major paravalvular leakage. Both groups showed sustained reductions in left atrial size and tricuspid regurgitation pressure gradient, accompanied by parallel improvements in New York Heart Association functional class (all time effect <em>P</em> < .001).</div></div><div><h3>Conclusions</h3><div>First-time and redo MVR with the MITRIS RESILIA valve was associated with low perioperative mortality, favorable safety, and durable hemodynamic performance. These findings support its use across a broad spectrum of mitral valve diseases.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 618-624"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postpneumonectomy Syndrome: Follow-Up, Treatment, and Prevention","authors":"Domenico Galetta MD, PhD, Maria Serra MD","doi":"10.1016/j.atssr.2025.12.017","DOIUrl":"10.1016/j.atssr.2025.12.017","url":null,"abstract":"","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Page 476"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ten Commandments of Off-Pump Coronary Artery Bypass Surgery","authors":"Shahzad G. Raja FRCS(CTh)","doi":"10.1016/j.atssr.2025.09.027","DOIUrl":"10.1016/j.atssr.2025.09.027","url":null,"abstract":"<div><h3>Background</h3><div>Off-pump coronary artery bypass (OPCAB) surgery offers distinct advantages over conventional on-pump techniques, including reduced inflammatory response, lower stroke risk, and improved outcomes in high-risk patients. Despite these benefits, concerns persist regarding graft patency, incomplete revascularization, and technical complexity, limiting widespread adoption.</div></div><div><h3>Methods</h3><div>A focused literature review was conducted using PubMed-indexed sources published between 2000 and 2025. The medical subject heading term “coronary artery bypass, off-pump” was used in combination with keywords including “hemodynamic optimization,” “conversion,” “graft patency,” and “surgical training.” Only peer reviewed randomized trials, meta-analyses, guideline-based reviews, and expert consensus articles were included. Findings were synthesized to define 10 core principles for safe and reproducible OPCAB practice.</div></div><div><h3>Results</h3><div>The “Ten Commandments” address key domains: patient selection, contraindication management, team readiness, stabilization techniques, hemodynamic control, complete revascularization, conversion avoidance, skill acquisition, technical refinement, and evidence-based advocacy. Each principle is supported by clinical data and practical strategies. Innovations, such as intracoronary shunting, advanced stabilizers, and artificial intelligence-guided decision-making, enhance procedural reliability and outcomes.</div></div><div><h3>Conclusions</h3><div>OPCAB can be performed safely and effectively with structured preparation, multidisciplinary collaboration, and adherence to best practices. By embracing these commandments and integrating emerging technologies, surgical teams can overcome barriers to adoption, refine intraoperative techniques, and deliver individualized coronary revascularization with superior long-term outcomes.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 579-584"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angel Doño MD, Jane Zhao MD, MS, Brenden Sheridan MD, Calvin Jung MD, Jenna Davis MD, Jasmine Ngo BS, Ganpat Valaulikar MD, Thomas Ng MD
{"title":"Transoral Circular Stapler for Cervical Anastomosis During Esophagectomy","authors":"Angel Doño MD, Jane Zhao MD, MS, Brenden Sheridan MD, Calvin Jung MD, Jenna Davis MD, Jasmine Ngo BS, Ganpat Valaulikar MD, Thomas Ng MD","doi":"10.1016/j.atssr.2025.10.002","DOIUrl":"10.1016/j.atssr.2025.10.002","url":null,"abstract":"<div><h3>Background</h3><div>This report describes a transoral circular stapling technique for cervical anastomosis during esophagectomy.</div></div><div><h3>Methods</h3><div>After the gastric conduit is delivered into the neck, the plastic guide of the transoral circular anvil is passed through the mouth and retrieved through a small opening made in the center of the linear cervical esophagus staple line, facilitating the passage of the circular anvil through the mouth into the cervical esophagus. The stapler handle is introduced into the gastric conduit through a gastrotomy created in the excess stomach, the spike is advanced, puncturing the greater curvature of the more distal conduit, connected to the circular anvil, and fired. The excess gastric conduit, including the gastrotomy site, is resected using a linear stapler.</div></div><div><h3>Results</h3><div>Ten consecutive patients (3 women, 7 men) underwent cervical anastomoses (6 transhiatal and 4 three-incision esophagectomy). Median age was 62 years, median body mass index was 24 kg/m<sup>2</sup>, median blood loss was 350 mL, and median operative time was 285 minutes. Pathology included 2 patients with extensive high-grade dysplasia, 1 with refractory reflux-induced stricture, and 7 with malignancy (adenocarcinoma in 6 and squamous cell carcinoma in 1). All patients had complete esophageal and gastric donuts and were without leak during intraoperative endoscopy. There were no clinical or radiographic anastomotic leaks or strictures and no mortality at 90 days.</div></div><div><h3>Conclusions</h3><div>Cervical anastomosis with the transoral circular stapler is feasible. The technique is reproducible and results in a consistent and widely patent anastomosis with low leak and stricture rates. Larger studies are warranted to confirm our results.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 483-487"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Klipsch MD , Lauren Fanning MPH , Jeffrey E. Korte PhD , Maxwell Kilcoyne DO , Binh Trang HSD , David Mann DO , Barry C. Gibney DO , Arman Kilic MD , Kathryn E. Engelhardt MD, MS
{"title":"Are Lung Allografts From Drug Overdose Deaths Safe to Use for Transplantation? A Nationwide Analysis","authors":"Eric Klipsch MD , Lauren Fanning MPH , Jeffrey E. Korte PhD , Maxwell Kilcoyne DO , Binh Trang HSD , David Mann DO , Barry C. Gibney DO , Arman Kilic MD , Kathryn E. Engelhardt MD, MS","doi":"10.1016/j.atssr.2025.10.011","DOIUrl":"10.1016/j.atssr.2025.10.011","url":null,"abstract":"<div><h3>Background</h3><div>The increase in drug overdose deaths (DODs) has resulted in an increased pool of potential organ donors. We assessed the pattern of use of DOD donors and describe outcomes of lung transplant recipients who received allografts from DOD donors.</div></div><div><h3>Methods</h3><div>The United Network for Organ Sharing registry was used to identify all adult (aged ≥18 years) isolated lung transplant recipients between January 2010 and June 2022. Recipient allografts from DOD donors were compared with allografts from donors who died of other causes. Long-term survival was assessed with unadjusted Kaplan-Meier curves, the log-rank test, and risk-adjusted multivariable Cox proportional hazards models.</div></div><div><h3>Results</h3><div>We identified 28,495 adult lung recipients who met inclusion criteria, and 12.1% (n = 3437) received allografts from DOD donors. The yearly volume of DOD recipients nationwide increased from 67 in 2010 to 531 in 2022 (Mann-Kendall trend test, <em>P</em> < .001). Survival did not significantly differ between DOD and non-DOD recipients at 30 days (hazard ratio, 0.96; 95% CI, 0.76-1.23), 1 year (hazard ratio, 1.04; 95% CI, 0.92-1.17), or 3 years (hazard ratio, 1.04; 95% CI, 0.96-1.12). DOD recipients had longer average length of stay (27.7 vs 27.4 days), were less likely to have no postoperative ventilatory support (1.6% vs 2.9%), and a greater proportion were intubated at 72 hours (25.4% vs 21.6%).</div></div><div><h3>Conclusions</h3><div>Use of DOD lungs in lung transplantation has increased in the last decade. Long-term recipient outcomes were similar compared with all other donors. These results support the safety of using DOD lungs.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 705-711"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148104070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saif Ali BS , Jason Liu BS , Katherine Braley MD , Sofia Salazar PhD , Peter Wearden MD, PhD , Kellianne Kleeman MD , Vanessa Hormaza MD , Jennifer Nelson MD, MS
{"title":"Surgical Treatment of Accessory Mitral Valve Tissue in a Toddler","authors":"Saif Ali BS , Jason Liu BS , Katherine Braley MD , Sofia Salazar PhD , Peter Wearden MD, PhD , Kellianne Kleeman MD , Vanessa Hormaza MD , Jennifer Nelson MD, MS","doi":"10.1016/j.atssr.2025.11.012","DOIUrl":"10.1016/j.atssr.2025.11.012","url":null,"abstract":"<div><div>Accessory mitral valve tissue causing left ventricular outflow tract obstruction is exceedingly rare in children. We present the surgical treatment of a toddler with severe obstruction due to type IIa accessory mitral valve tissue. Intraoperatively, the accessory tissue resembled a duplicated mature mitral valve leaflet. Surgical treatment included a septal myectomy and imbrication of the accessory tissue without leaflet resection, which successfully relieved the obstruction and preserved valve function. This case emphasizes the importance of awareness of this diagnosis and classification system as standard mitral repair techniques may not be appropriate or effective, depending on the anatomic subtype.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 670-673"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148104060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nikaidoh Procedure for Double Outlet Right Ventricle With Transposition of the Great Arteries and Superior-Inferior Ventricles","authors":"Szu-Yen Hu MD , Heng-Wen Chou MD , Yi-Chia Wang MD, PhD , Shyh-Jye Chen MD, PhD , Yih-Sharng Chen MD, PhD , Shu-Chien Huang MD, PhD","doi":"10.1016/j.atssr.2025.12.002","DOIUrl":"10.1016/j.atssr.2025.12.002","url":null,"abstract":"<div><div>We report a rare case of double outlet right ventricle with transposition of the great arteries, subpulmonary ventricular septal defect, pulmonary valve stenosis, and superior-inferior ventricles successfully managed by the Nikaidoh procedure. Preoperative 3-dimensional simulation clarified the complex spatial anatomy and confirmed feasibility without inflow compromise. Surgical results mirrored the simulation, with smooth recovery and excellent 4-year outcome. The Nikaidoh procedure is feasible in cases with superior-inferior ventricular arrangement and pulmonary stenosis, and 3-dimensional simulation can facilitate precise surgical planning, potentially improving outcomes in similarly complex congenital heart defects.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 2","pages":"Pages 678-682"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148104062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}