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Annals of internal medicine. Clinical cases最新文献

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Severe, Refractory Primary Warm Autoimmune Hemolytic Anemia Requiring 90 Erythrocyte Transfusions. 需要输注 90 次红细胞的严重难治性原发性温暖自身免疫性溶血性贫血。
Annals of internal medicine. Clinical cases Pub Date : 2024-05-01 Epub Date: 2024-05-07 DOI: 10.7326/aimcc.2023.1141
Neeharika Namineni, Christina Waldron, Christopher Tormey, George Goshua
{"title":"Severe, Refractory Primary Warm Autoimmune Hemolytic Anemia Requiring 90 Erythrocyte Transfusions.","authors":"Neeharika Namineni, Christina Waldron, Christopher Tormey, George Goshua","doi":"10.7326/aimcc.2023.1141","DOIUrl":"10.7326/aimcc.2023.1141","url":null,"abstract":"<p><p>A previously healthy 60-year-old man presented to the hospital with a hemoglobin of 3.5 g/dL. He was diagnosed with severe warm autoimmune hemolytic anemia (wAIHA) with reticulocytopenia on hospital day 1 that was not responsive to steroids, immune globulin, and rituximab. Over a 42-day hospital stay, the patient remained continuously transfusion-dependent with a ninety red cell unit requirement for his refractory disease. He was trialed on therapeutic plasma exchange before ultimately undergoing inpatient splenectomy that led to a response within hours. He remains in complete remission at six months of follow-up.</p>","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11081177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ischemic Complications of Giant-Cell Arteritis 巨细胞动脉炎的缺血性并发症
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0560
Fátima Raad, Vicente Ramos Polledo, Andreu Fernández-Codina, Fernando De La Iglesia Martínez
{"title":"Ischemic Complications of Giant-Cell Arteritis","authors":"Fátima Raad, Vicente Ramos Polledo, Andreu Fernández-Codina, Fernando De La Iglesia Martínez","doi":"10.7326/aimcc.2023.0560","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0560","url":null,"abstract":"Giant-cell arteritis (GCA) is a medium- to large-vessel arteritis predominantly involving the branches of the aorta, occurring in elderly patients. Findings in GCA include symptoms such as headache, jaw claudication, or polymyalgia rheumatica; ischemic events; and signs of a systemic inflammatory reaction. The clinical presentation may rarely involve other areas. We report the case of an 85-year-old man with biopsy-proven GCA presenting with fever, weight loss, and scalp necrosis.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"26 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Strokes in a Hypertensive Smoker: An Atypical Case and Review of Thrombotic Thrombocytopenic Purpura 高血压吸烟者的复发性卒中:血栓性血小板减少性紫癜的一个不典型病例和回顾
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0424
Nithya Ramesh, Shanjeev Kumar Rajeshkumar Chitra, Udunma Ikoro, Sohiel Deshpande, Vartika Singh, Vidhi Mehta, Andre Posner
{"title":"Recurrent Strokes in a Hypertensive Smoker: An Atypical Case and Review of Thrombotic Thrombocytopenic Purpura","authors":"Nithya Ramesh, Shanjeev Kumar Rajeshkumar Chitra, Udunma Ikoro, Sohiel Deshpande, Vartika Singh, Vidhi Mehta, Andre Posner","doi":"10.7326/aimcc.2023.0424","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0424","url":null,"abstract":"Thrombotic thrombocytopenic purpura (TTP) can present with neurologic symptoms before the development of typical hematologic abnormalities. We describe a patient presenting with decreased grip strength in his right hand who was found to have an ischemic stroke from acute TTP. In the setting of subtle hematologic abnormalities, detection of severely decreased ADAMTS13 activity aided in early diagnosis and prompt initiation of plasmapheresis. Hence, we emphasize the need for high clinical suspicion for TTP in patients with recurrent and cryptogenic strokes, especially in the setting of subtle hematologic findings, as early treatment decreases mortality rate by almost 90%.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"27 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recognition and Treatment of a Right Ventricular Air Embolism 右心室空气栓塞的识别与治疗
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0817
Leon Sun, Katherine I. Harris
{"title":"Recognition and Treatment of a Right Ventricular Air Embolism","authors":"Leon Sun, Katherine I. Harris","doi":"10.7326/aimcc.2023.0817","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0817","url":null,"abstract":"Right ventricular air embolism is a rare and dangerous condition that frequently presents with nonspecific symptoms, making diagnosis difficult. We present a case involving a young woman with concerning symptoms following routine injection of contrast. Computed tomography scan visualizing the heart confirmed the finding of a large air embolism. We describe the immediate actions taken and the subsequent treatment provided.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Heterozygous Variant of TGFB3 in a Patient With an Atypical Presentation of Loeys–Dietz Syndrome: A Case Report 一个不典型Loeys-Dietz综合征患者的TGFB3杂合变异:一个病例报告
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0035
Tarika D. Patel, Meagan N. McNicholas, Christina M. Laukaitis
{"title":"A Heterozygous Variant of <i>TGFB3</i> in a Patient With an Atypical Presentation of Loeys–Dietz Syndrome: A Case Report","authors":"Tarika D. Patel, Meagan N. McNicholas, Christina M. Laukaitis","doi":"10.7326/aimcc.2023.0035","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0035","url":null,"abstract":"Loeys–Dietz syndrome (LDS) 5 is characterized by aortic aneurysms, hypertelorism, and cleft palate/bifid uvula. We describe a woman with a transforming growth factor beta3 (TGFβ3) mutation who displays a forme fruste phenotype of LDS5. A 43-year-old woman with joint pain and hypermobile joints underwent evaluation for hypermobile Ehlers–Danlos syndrome. Her features included pes planus, treated high-arched palate, and increased joint mobility. Genetic analysis identified a pathogenic TGFβ3 variant (c.427A>T, p.Arg143*), clarifying the diagnosis of LDS5. Comparing our patient with others with TGFB3 mutations illustrated the diversity of LDS5 features, often a milder forme fruste form, which warrants more investigation due to insufficient characterization.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"23 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraneoplastic Leukemoid Reaction in High-Grade Lung Adenocarcinoma Complicated by Triple Co-Mutations 高级别肺腺癌并发三重共突变的副肿瘤样白血病反应
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0502
Kim L. Tran, Seema R. Walvekar, Brian C. Boulmay, Sarah W. Lungaro, Jasmine L. Taylor
{"title":"Paraneoplastic Leukemoid Reaction in High-Grade Lung Adenocarcinoma Complicated by Triple Co-Mutations","authors":"Kim L. Tran, Seema R. Walvekar, Brian C. Boulmay, Sarah W. Lungaro, Jasmine L. Taylor","doi":"10.7326/aimcc.2023.0502","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0502","url":null,"abstract":"","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"27 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic Emboli and Biventricular Hypertrophy Due to Glycogen Storage Disease: Clinical, Imaging, and Pathologic Predicament 糖原蓄积病引起的全身栓塞和双心室肥厚:临床、影像学和病理困境
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0463
Amirhossein Esmaeeli, Prashant Nagpal, Jefree J. Schulte, Sofia C. Masri, Peter S. Rahko
{"title":"Systemic Emboli and Biventricular Hypertrophy Due to Glycogen Storage Disease: Clinical, Imaging, and Pathologic Predicament","authors":"Amirhossein Esmaeeli, Prashant Nagpal, Jefree J. Schulte, Sofia C. Masri, Peter S. Rahko","doi":"10.7326/aimcc.2023.0463","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0463","url":null,"abstract":"Glycogen storage disease cardiomyopathy is being recognized increasingly as a mimicker of hypertrophic cardiomyopathy. It is important to diagnose these diseases, as there are prognostic and treatment ramifications. This case report discusses a patient who presented with cardioembolic renal infarction and was ultimately diagnosed with glycogen storage disease XV (which is extremely rare). The diagnosis was made by pursuing multimodality imaging, endomyocardial biopsy, and genetic testing.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"24 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Troubleshooting for Acute Cholecystitis With a Stone Impacted in the Cystic Duct 内窥镜诊断胆囊管内结石嵌塞的急性胆囊炎
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0101
Sakue Masuda, Kazuya Koizumi, Takayoshi Tsuchiya, Makomo Makazu, Ryuuhei Jinushi, Kento Shionoya, Karen Kimura, Takashi Nishino, Chikamasa Ichita, Akiko Sasaki
{"title":"Endoscopic Troubleshooting for Acute Cholecystitis With a Stone Impacted in the Cystic Duct","authors":"Sakue Masuda, Kazuya Koizumi, Takayoshi Tsuchiya, Makomo Makazu, Ryuuhei Jinushi, Kento Shionoya, Karen Kimura, Takashi Nishino, Chikamasa Ichita, Akiko Sasaki","doi":"10.7326/aimcc.2023.0101","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0101","url":null,"abstract":"Endoscopic transpapillary gallbladder drainage is considered an alternative procedure in patients with acute cholecystitis who are not surgical candidates; however, it remains challenging, especially in cases with a stone impacted into the cystic duct (CD). In cases in which a stone is impacted at the CD orifice, a cholangioscope and forceps may be used to release the stone. In cases in which the stone is impacted in the middle of the CD, contrast pressure from above the injection retrieval balloon may be used to push the stone toward the gallbladder. We believe this is the first report of such cases in the literature.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"24 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stress Cardiomyopathy in Chronic Obstructive Pulmonary Disease and Asthma Exacerbations: A Narrative Literature Review 慢性阻塞性肺疾病和哮喘加重的应激性心肌病:叙述性文献综述
Annals of internal medicine. Clinical cases Pub Date : 2023-11-01 DOI: 10.7326/aimcc.2023.0953
C. Divyash Chhetri, Shahan Haseeb, Juby Roy, Umair Ansari, Eric Gehres, Rohan Perera, Andrew Weber, Alan Kaell
{"title":"Stress Cardiomyopathy in Chronic Obstructive Pulmonary Disease and Asthma Exacerbations: A Narrative Literature Review","authors":"C. Divyash Chhetri, Shahan Haseeb, Juby Roy, Umair Ansari, Eric Gehres, Rohan Perera, Andrew Weber, Alan Kaell","doi":"10.7326/aimcc.2023.0953","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0953","url":null,"abstract":"In patients with asthma or chronic obstructive pulmonary disease exacerbations, the association between use of β-adrenergic agonists and stress cardiomyopathy is becoming increasingly recognized. Considering the emergence of this association, we sought to consolidate information from the existing body of literature to derive observational trends. One case series and 8 case reports were reviewed. Sex, age, ethnicity, comorbid conditions, presenting symptoms, electrocardiogram findings, troponin values, amount and type of β-agonist used, and time to resolution of cardiomyopathy were examined.","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Ocular Syphilis With Bilateral Central Visual Loss in a Young Man Who Was Negative for HIV 一例罕见的眼部梅毒伴双侧中央视力丧失的年轻男性HIV阴性
Annals of internal medicine. Clinical cases Pub Date : 2023-10-01 DOI: 10.7326/aimcc.2023.0292
Abdallah Mughrabi, Rinat Nuriev, Tinzar Basein
{"title":"A Rare Case of Ocular Syphilis With Bilateral Central Visual Loss in a Young Man Who Was Negative for HIV","authors":"Abdallah Mughrabi, Rinat Nuriev, Tinzar Basein","doi":"10.7326/aimcc.2023.0292","DOIUrl":"https://doi.org/10.7326/aimcc.2023.0292","url":null,"abstract":"","PeriodicalId":72222,"journal":{"name":"Annals of internal medicine. Clinical cases","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134931113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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