Advances in chronic kidney disease最新文献_第5页

Young Adults With Hereditary Tubular Diseases: Practical Aspects for Adult-Focused Colleagues 患有遗传性小管疾病的年轻人:为关注成人的同事提供的实用方面

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-05-01 DOI: 10.1053/j.ackd.2021.11.004

Khalid Alhasan , Cynthia D'Alessandri-Silva , Anil Mongia , Rezan Topaloglu , Velibor Tasic , Guido Filler

{"title":"Young Adults With Hereditary Tubular Diseases: Practical Aspects for Adult-Focused Colleagues","authors":"Khalid Alhasan , Cynthia D'Alessandri-Silva , Anil Mongia , Rezan Topaloglu , Velibor Tasic , Guido Filler","doi":"10.1053/j.ackd.2021.11.004","DOIUrl":"10.1053/j.ackd.2021.11.004","url":null,"abstract":"<div>Recent advances in the management of kidney tubular diseases have resulted in a significant cohort of adolescents and young adults transitioning from pediatric- to adult-focused care. Most of the patients under adult-focused care have glomerular diseases, whereas rarer tubular diseases form a considerable proportion of pediatric patients. The purpose of this review is to highlight the clinical signs and symptoms of tubular disorders, as well as their diagnostic workup, including laboratory findings and imaging, during young adulthood. We will then discuss more common disorders such as cystinosis, cystinuria, distal kidney tubular acidosis, congenital nephrogenic diabetes insipidus, Dent disease, rickets, hypercalciuria, and syndromes such as Bartter, Fanconi, Gitelman, Liddle, and Lowe. This review is a practical guide on the diagnostic and therapeutic approach of tubular conditions affecting young adults who are transitioning to adult-focused care.</div>","PeriodicalId":7221,"journal":{"name":"Advances in chronic kidney disease","volume":"29 3","pages":"Pages 292-307"},"PeriodicalIF":2.9,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Guide for Adult Nephrologists and Hematologists to Managing Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy in Teens Transitioning to Young Adults 成人肾病学家和血液学家管理青少年过渡到年轻人的非典型溶血性尿毒症综合征和C3肾小球病指南

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-05-01 DOI: 10.1053/j.ackd.2022.04.003

Magdalena Riedl Khursigara , Mina Matsuda-Abedini , Seetha Radhakrishnan , Michelle A. Hladunewich , Mathieu Lemaire , Chia Wei Teoh , Damien Noone , Christoph Licht

{"title":"A Guide for Adult Nephrologists and Hematologists to Managing Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy in Teens Transitioning to Young Adults","authors":"Magdalena Riedl Khursigara , Mina Matsuda-Abedini , Seetha Radhakrishnan , Michelle A. Hladunewich , Mathieu Lemaire , Chia Wei Teoh , Damien Noone , Christoph Licht","doi":"10.1053/j.ackd.2022.04.003","DOIUrl":"10.1053/j.ackd.2022.04.003","url":null,"abstract":"<div>Atypical hemolytic uremic syndrome and C3 glomerulopathy/immune complex membranoproliferative glomerulonephritis are ultra-rare chronic, complement-mediated diseases with childhood manifestation in a majority of cases. Transition of clinical care of patients from pediatric to adult nephrologists—typically with controlled disease in native or transplant kidneys in case of atypical hemolytic uremic syndrome and often with chronic progressive disease despite treatment efforts in case of C3 glomerulopathy/immune complex membranoproliferative glomerulonephritis—identifies a challenging juncture in the journey of these patients. Raising awareness for the vulnerability of this patient cohort; providing education on disease pathophysiology and management including the use of new, high-precision complement antagonists; and establishing an ongoing dialog of patients, families, and all members of the health care team involved on either side of the age divide will be inevitable to ensure optimal patient outcomes and a safe transition of these patients to adulthood.</div>","PeriodicalId":7221,"journal":{"name":"Advances in chronic kidney disease","volume":"29 3","pages":"Pages 231-242"},"PeriodicalIF":2.9,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Spectrum of Nephrotic Syndrome: Impact of Podocytopathy in Adult Life 肾病综合征的遗传谱:足细胞病在成人生活中的影响

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-05-01 DOI: 10.1053/j.ackd.2022.04.005

Susan Massengill , Howard Trachtman

引用次数: 1

Health Care Transition in Adolescents and Young Adults With Chronic Kidney Disease: Focus on the Individual and Family Support Systems 青少年和青年慢性肾病患者的医疗保健转变:关注个人和家庭支持系统

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-05-01 DOI: 10.1053/j.ackd.2022.02.004

Cozumel S. Pruette , Daniel Ranch , Weiwen Vivian Shih , Maria Diaz-Gonzalez Ferris

{"title":"Health Care Transition in Adolescents and Young Adults With Chronic Kidney Disease: Focus on the Individual and Family Support Systems","authors":"Cozumel S. Pruette , Daniel Ranch , Weiwen Vivian Shih , Maria Diaz-Gonzalez Ferris","doi":"10.1053/j.ackd.2022.02.004","DOIUrl":"10.1053/j.ackd.2022.02.004","url":null,"abstract":"<div>Health care transition (HCT) from pediatric to adult-focused services is a longitudinal process driven by the collaboration and interactions of adolescent/young adult patients, their families, providers, health care agencies, and environment. Health care providers in both pediatric and adult-focused settings must collaborate, as patients' health self-management skills are acquired in the mid-20s, after they have transferred to adult-focused care. Our manuscript discusses the individual and family support systems as they relate to adolescents and young adults with chronic or end-stage kidney disease. In the individual domain, we discuss demographic/socioeconomic characteristics, disease complexity/course, cognitive capabilities, and self-management/self-advocacy. In the family domain, we discuss family composition/culture factors, family function, parenting style, and family unit factors. We provide a section dedicated to patients with cognitive and developmental disability. Furthermore, we discuss barriers for HCT preparation and offer solutions as well as activities for HCT preparation.</div>","PeriodicalId":7221,"journal":{"name":"Advances in chronic kidney disease","volume":"29 3","pages":"Pages 318-326"},"PeriodicalIF":2.9,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Onconephrology: The Growth of Cancer–Kidney Connection, Part 2 肿瘤学:肿瘤与肾脏的联系，第二部分

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2022.05.001

Prakash Gudsoorkar MD, Kenar D. Jhaveri MD, Meghan E. Sise MD, MS

引用次数: 1

Kidney Disease Following Hematopoietic Stem Cell Transplantation 造血干细胞移植后肾脏疾病

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2021.11.003

Ala Abudayyeh , Rimda Wanchoo

引用次数: 2

Sodium and Potassium Dysregulation in the Patient With Cancer 癌症患者的钠钾失调

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2022.01.003

Praveen Ratanasrimetha , Biruh T. Workeneh , Harish Seethapathy

{"title":"Sodium and Potassium Dysregulation in the Patient With Cancer","authors":"Praveen Ratanasrimetha , Biruh T. Workeneh , Harish Seethapathy","doi":"10.1053/j.ackd.2022.01.003","DOIUrl":"10.1053/j.ackd.2022.01.003","url":null,"abstract":"<div>Sodium and potassium disorders are pervasive in patients with cancer. The causes of these abnormalities are wide-ranging, are often primary or second-order consequences of the underlying cancer, and have prognostic implications. The approach to hyponatremia should focus on cancer-related etiologies, such as syndrome of inappropriate antidiuretic hormone, to the exclusion of other causes. Hypernatremia in non-iatrogenic forms is generally due to water loss rather than excessive sodium intake. Debilitated or dependent patients with cancer are particularly vulnerable to hypernatremia. Hypokalemia can occur in patients with cancer due to gastrointestinal disturbances, resulting from decreased intake or increased losses. Renal losses can occur as a result of excessive mineralocorticoid secretion or therapy-related nephrotoxicity. The approach to hyperkalemia should be informed by historical and laboratory clues, and pseudohyperkalemia is particularly common in patients with hematological cancers. Hyperkalemia can be seen in primary or metastatic disease that interrupts the adrenal axis. It can also develop as a consequence of immunotherapy, which can cause adrenalitis or hypophysitis. Tumor lysis syndrome (TLS) is defined by the development of hyperkalemia and is a medical emergency. Awareness of the electrolyte abnormalities that can befall patients with cancer is vital for its prompt recognition and management.</div>","PeriodicalId":7221,"journal":{"name":"Advances in chronic kidney disease","volume":"29 2","pages":"Pages 171-179.e1"},"PeriodicalIF":2.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40581822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Palliative Care for Patients With Cancer and Kidney Disease 癌症和肾脏疾病患者的姑息治疗

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2021.11.007

Antonio G. Corona , Pablo Garcia , Samantha L. Gelfand

引用次数: 1

Monoclonal Gammopathy–Related Kidney Diseases 单克隆伽玛病相关肾病

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2022.01.004

Janina Paula T. Sy-Go , Sandra M. Herrmann , Surya V. Seshan

{"title":"Monoclonal Gammopathy–Related Kidney Diseases","authors":"Janina Paula T. Sy-Go , Sandra M. Herrmann , Surya V. Seshan","doi":"10.1053/j.ackd.2022.01.004","DOIUrl":"10.1053/j.ackd.2022.01.004","url":null,"abstract":"<div>Monoclonal gammopathies occur secondary to a broad range of clonal B lymphocyte or plasma cell disorders, producing either whole or truncated monoclonal immunoglobulins. The kidneys are often affected by these monoclonal proteins, and, although not mutually exclusive, can involve the glomeruli, tubules, interstitium, and vasculature. The nephrotoxic potential of these monoclonal proteins is dependent on a variety of physicochemical characteristics that are responsible for the diverse clinicopathologic manifestations, including glomerular diseases with organized deposits, glomerular diseases with granular deposits, and other lesions, such as C3 glomerulopathy and thrombotic microangiopathy with unique pathophysiologic features. The diseases that involve primarily the tubulointerstitial and vascular compartments are light chain cast nephropathy, light chain proximal tubulopathy, crystal-storing histiocytosis, and crystalglobulin-induced nephropathy with distinct acute and chronic clinicopathologic features. The diagnosis of a monoclonal gammopathy–related kidney disease is established by identification of an underlying active or more commonly, low-grade hematologic malignancy, serologic evidence of a monoclonal gammopathy when detectable, and most importantly, monoclonal protein–induced pathologic lesions seen in a kidney biopsy, confirming the association with the monoclonal protein. Establishing a diagnosis may be challenging at times, particularly in the absence of an overt hematologic malignancy, with or without monoclonal gammopathy, such as proliferative glomerulonephritis with monoclonal immunoglobulin deposits. Overall, the treatment is directed against the underlying hematologic disorder and the potential source of the monoclonal protein.</div>","PeriodicalId":7221,"journal":{"name":"Advances in chronic kidney disease","volume":"29 2","pages":"Pages 86-102.e1"},"PeriodicalIF":2.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40581827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Anemia Management in the Cancer Patient With CKD and End-Stage Kidney Disease CKD合并终末期肾病的癌症患者的贫血管理

IF 2.9 3区医学

Advances in chronic kidney disease Pub Date : 2022-03-01 DOI: 10.1053/j.ackd.2022.03.005

Arash Rashidi , Pranav S. Garimella , Abdullah Al-Asaad , Talar Kharadjian , Mariela Navarro Torres , Jyotsana Thakkar

引用次数: 2