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The history of thrombotic thrombocytopenic purpura research: a narrative review. 血栓性血小板减少性紫癜研究史：叙事性回顾。
Annals of blood Pub Date : 2024-06-30 Epub Date: 2024-02-16 DOI: 10.21037/aob-23-46
Konstantine Halkidis, Bernhard Lämmle, X Long Zheng
{"title":"The history of thrombotic thrombocytopenic purpura research: a narrative review.","authors":"Konstantine Halkidis, Bernhard Lämmle, X Long Zheng","doi":"10.21037/aob-23-46","DOIUrl":"10.21037/aob-23-46","url":null,"abstract":"<p><strong>Background and objective: </strong>Thrombotic thrombocytopenic purpura (TTP) is a rare but debilitating thrombotic microangiopathy that results from severe deficiency of the enzyme ADAMTS13. The disorder was first described in the early 20<sup>th</sup> century, but the pathophysiology of the disease has only been elucidated in the past three decades. In this narrative review, we will summarize the milestone moments in the history of TTP research and discovery.</p><p><strong>Methods: </strong>We searched literature using PubMed from 1924 to 2023 using the following free text searches: \"thrombotic thrombocytopenic purpura\", \"Moschcowitz disease\", and \"thrombotic microangiopathy\". We found 6,917 peer-reviewed articles and sorted through these for relevant literature pertinent to the review. A total of 46 articles were included for review and the remainder were excluded.</p><p><strong>Key content and findings: </strong>The history of TTP research was reviewed, with a sampling of major events in the evolution of the understanding of the pathophysiology and treatment of the disease discussed here. There remains much to be learned about the nature of the disease in order to develop more specific and less harmful treatments.</p><p><strong>Conclusions: </strong>An overview of the major discoveries that have led to our current understanding of TTP reveals the results of collaboration of multiple groups of physicians and scientists through the past century, with additional breakthroughs likely to occur in the future because of that same collaborative spirit.</p>","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"9 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141763006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introductory comments about the special series of thrombotic microangiopathy. 关于血栓性微血管病特别系列的介绍性评论。
Annals of blood Pub Date : 2024-06-30 Epub Date: 2024-04-01 DOI: 10.21037/aob-24-6
X Long Zheng
{"title":"Introductory comments about the special series of thrombotic microangiopathy.","authors":"X Long Zheng","doi":"10.21037/aob-24-6","DOIUrl":"10.21037/aob-24-6","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"9 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141763005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rh D-positive genotypes in Brazilian blood donors with D-negative phenotype 巴西献血者中 Rh D 阳性基因型的 D 阴性表型
Annals of blood Pub Date : 2024-06-01 DOI: 10.21037/aob-23-61
E. Rodrigues, Flávia Leite Souza Santos, T. A. de Paula Vendrame, Talitha Baldin Cuter, A. Romagnoli, Vanessa Mendes, Lilian Beatriz Moreira de Oliveira Chagas, D. Covas, Lilian Castilho, Simone Kashima
{"title":"Rh D-positive genotypes in Brazilian blood donors with D-negative phenotype","authors":"E. Rodrigues, Flávia Leite Souza Santos, T. A. de Paula Vendrame, Talitha Baldin Cuter, A. Romagnoli, Vanessa Mendes, Lilian Beatriz Moreira de Oliveira Chagas, D. Covas, Lilian Castilho, Simone Kashima","doi":"10.21037/aob-23-61","DOIUrl":"https://doi.org/10.21037/aob-23-61","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"5 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141279148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blinatumomab as frontline therapy for B-cell precursor acute lymphoblastic leukemia in a critically ill young adult: a case report Blinatumomab 作为一线疗法治疗一名重症年轻成人的 B 细胞前体急性淋巴细胞白血病：病例报告
Annals of blood Pub Date : 2024-06-01 DOI: 10.21037/aob-24-7
Carolina Mendez-Guerra, Carlos Ignacio Reyes-Farias, Luis Uribe-Ramirez, Antonio Carrasco-Yalan
{"title":"Blinatumomab as frontline therapy for B-cell precursor acute lymphoblastic leukemia in a critically ill young adult: a case report","authors":"Carolina Mendez-Guerra, Carlos Ignacio Reyes-Farias, Luis Uribe-Ramirez, Antonio Carrasco-Yalan","doi":"10.21037/aob-24-7","DOIUrl":"https://doi.org/10.21037/aob-24-7","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"53 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous immunoglobulin can induce antibody-dependent cell-mediated cytotoxicity and upregulate FCGR3A and FcγRIIIA expression in vitro 静脉注射免疫球蛋白可在体外诱导抗体依赖性细胞介导的细胞毒性，并上调 FCGR3A 和 FcγRIIIA 的表达
Annals of blood Pub Date : 2024-06-01 DOI: 10.21037/aob-23-42
Liyuan Zhu, Yafei Zhao, Gang Ye, Yuwei Huang, Qing Liu, Peng Jiang, Changqing Li, Xi Du, Shengliang Ye, Li Ma
{"title":"Intravenous immunoglobulin can induce antibody-dependent cell-mediated cytotoxicity and upregulate FCGR3A and FcγRIIIA expression in vitro","authors":"Liyuan Zhu, Yafei Zhao, Gang Ye, Yuwei Huang, Qing Liu, Peng Jiang, Changqing Li, Xi Du, Shengliang Ye, Li Ma","doi":"10.21037/aob-23-42","DOIUrl":"https://doi.org/10.21037/aob-23-42","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"66 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141277447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune-mediated thrombotic thrombocytopenic purpura landscaping in Gulf countries: a real-world evidence study (ATHENA Study) 海湾国家免疫介导的血栓性血小板减少性紫癜景观：真实世界证据研究（ATHENA 研究）
Annals of blood Pub Date : 2024-03-01 DOI: 10.21037/aob-23-29
Mona Al Rasheed, Faisal Alsayegh, Fahad Al Mohareb, Adel A. Aljatham, Farjah H Alqahtani, Hafiz Malhan, H. Y. Osman, Hasan Aal-Yaseen, Hind Salama, H. A. Al Saeed, Lulwah Al-Tourah, Maha Sallam, Mahmoud Marashi, Mohamad Qari, Mona Oyar Hosseini, M. Al-Khabori, Neveen Shalaby, O. Kashari, Ruba Y. Taha, Sabria Alhashami, Ahmed Mekky, Magdy Rabea, Mina Naguib, Zahir Chouikrat
{"title":"Immune-mediated thrombotic thrombocytopenic purpura landscaping in Gulf countries: a real-world evidence study (ATHENA Study)","authors":"Mona Al Rasheed, Faisal Alsayegh, Fahad Al Mohareb, Adel A. Aljatham, Farjah H Alqahtani, Hafiz Malhan, H. Y. Osman, Hasan Aal-Yaseen, Hind Salama, H. A. Al Saeed, Lulwah Al-Tourah, Maha Sallam, Mahmoud Marashi, Mohamad Qari, Mona Oyar Hosseini, M. Al-Khabori, Neveen Shalaby, O. Kashari, Ruba Y. Taha, Sabria Alhashami, Ahmed Mekky, Magdy Rabea, Mina Naguib, Zahir Chouikrat","doi":"10.21037/aob-23-29","DOIUrl":"https://doi.org/10.21037/aob-23-29","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":" 644","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges with assigning RH alleles and accurately predicting phenotypes using commercially-available genotyping kits: a narrative review 使用市售基因分型试剂盒分配 RH 等位基因和准确预测表型所面临的挑战：叙述性综述
Annals of blood Pub Date : 2024-03-01 DOI: 10.21037/aob-23-18
Margaret A. Keller
{"title":"Challenges with assigning RH alleles and accurately predicting phenotypes using commercially-available genotyping kits: a narrative review","authors":"Margaret A. Keller","doi":"10.21037/aob-23-18","DOIUrl":"https://doi.org/10.21037/aob-23-18","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"106 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140089970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient blood management, past, present and future 患者血液管理，过去、现在和未来
Annals of blood Pub Date : 2024-03-01 DOI: 10.21037/aob-22-45
R. Gammon, Nour Almozain, Aikaj Jindal, Amita Radhakrishnan Nair, L. Vasovic, Christopher Bocquet
{"title":"Patient blood management, past, present and future","authors":"R. Gammon, Nour Almozain, Aikaj Jindal, Amita Radhakrishnan Nair, L. Vasovic, Christopher Bocquet","doi":"10.21037/aob-22-45","DOIUrl":"https://doi.org/10.21037/aob-22-45","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":" 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140091270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of chronic myeloid leukemia (CML) in pregnant women: a comprehensive literature review 孕妇慢性髓性白血病（CML）的管理：综合文献综述
Annals of blood Pub Date : 2024-03-01 DOI: 10.21037/aob-23-34
Tala Najdi, Toufic Zeidan, Nizar El Bcherawi, Joyce Labaky, H. Kourie
{"title":"Management of chronic myeloid leukemia (CML) in pregnant women: a comprehensive literature review","authors":"Tala Najdi, Toufic Zeidan, Nizar El Bcherawi, Joyce Labaky, H. Kourie","doi":"10.21037/aob-23-34","DOIUrl":"https://doi.org/10.21037/aob-23-34","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140084017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current practice optimization suggestions and future perspectives on transfusion in patients supported by extracorporeal membrane oxygenation: a narrative review 关于体外膜氧合患者输血的当前优化建议和未来展望：叙述性综述
Annals of blood Pub Date : 2024-03-01 DOI: 10.21037/aob-23-11
Stefano Tigano, Filippo Sanfilippo, Paolo Capuano, A. Arcadipane, G. Martucci
{"title":"Current practice optimization suggestions and future perspectives on transfusion in patients supported by extracorporeal membrane oxygenation: a narrative review","authors":"Stefano Tigano, Filippo Sanfilippo, Paolo Capuano, A. Arcadipane, G. Martucci","doi":"10.21037/aob-23-11","DOIUrl":"https://doi.org/10.21037/aob-23-11","url":null,"abstract":"","PeriodicalId":72211,"journal":{"name":"Annals of blood","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140089400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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