AJOG global reports最新文献

{"title":"Venous thromboembolism with contraceptive use in females with sickle cell trait","authors":"Angela K. Phillips PhD, APRN ,&nbsp;Candy Wilson PhD, APRN, FAAN ,&nbsp;Anwar E. Ahmed PhD ,&nbsp;Arun Shet MD, PhD ,&nbsp;Margaret Bevans PhD, RN, FAAN","doi":"10.1016/j.xagr.2025.100497","DOIUrl":"10.1016/j.xagr.2025.100497","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>Sickle cell trait is the carrier state for sickle cell disease and occurs in 1 in 13 births in Black and African American families. Individuals with sickle cell trait are permitted to serve in the military. Some research studies have shown that individuals with sickle cell trait may be at increased risk for thromboembolic events. Contraceptive use, specifically combined hormonal contraceptives containing both estrogen and progesterone, has been linked to an increased risk of thromboembolic events. No research has been done to determine if there is an increased risk of venous thromboembolism in a population of females with sickle cell trait who do or do not take combined hormonal contraceptives.</div></div><div><h3>OBJECTIVE</h3><div>To determine if women with sickle cell trait who use combined hormonal contraceptives are at higher risk for venous thromboembolism compared with females with sickle cell trait who do not use combined hormonal contraceptives. Given the increased risk of venous thromboembolism in sickle cell trait individuals in the general population, we hypothesized that females with sickle cell trait exposed to combined hormonal contraceptives would experience higher venous thromboembolism rates than unexposed females with sickle cell trait.</div></div><div><h3>STUDY DESIGN</h3><div>Population-based retrospective cohort study of females with sickle cell trait identified from the Military Data Repository to evaluate venous thromboembolism after exposure to combined hormonal contraceptives or without exposure to combined hormonal contraceptives.</div></div><div><h3>RESULTS</h3><div>There were 15,440 unique females aged 18–44 years between 2005 and 2021 who had a diagnosis of sickle cell trait. Approximately 40% of females had an International Classification of Diseases code consistent with a prescription of a combined hormonal contraceptive. Thirty-three (0.2%) of the 15,440 females with sickle cell trait had experienced venous thromboembolism of any type. There was no difference in the prevalence of venous thromboembolism by combined hormonal contraceptive use (yes [0.18%] vs no [0.24%]; <em>P</em>=.454). Being older, married, nonactive-duty military status, smoking, and having a diagnosis of hypertension were associated with a higher prevalence of venous thromboembolism.</div></div><div><h3>CONCLUSION</h3><div>Although there was a small number of venous thromboembolism events, the findings of this study suggest that the use of combined hormonal contraceptives in females with sickle cell trait is not associated with a detectable signal for increased venous thromboembolism risk as an outcome. Given the potential clinical benefit of combined hormonal contraceptives in pregnancy prevention and menstrual regulation in females, the concerns about combined hormonal contraceptive-associated venous thromboembolism in this population with sickle cell trait seem to be minimal.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100497"},"PeriodicalIF":0.0,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International pregnancy loss/ miscarriage day posts shared on Instagram: a content analysis","authors":"Atikah Sayogo Putri ,&nbsp;Achmad Kemal Harzif ,&nbsp;Putri Nurbaeti ,&nbsp;Aisyah Retno Puspawardani ,&nbsp;Nafi'atul Ummah ,&nbsp;Shakira Amirah ,&nbsp;Muhammad Candrika Agyawisnu Yuwono ,&nbsp;Mila Maidarti ,&nbsp;Kanadi Sumapraja","doi":"10.1016/j.xagr.2025.100487","DOIUrl":"10.1016/j.xagr.2025.100487","url":null,"abstract":"<div><h3>Background</h3><div>Miscarriage refers to the loss of a fetus before the completion of 28 weeks of gestation. The prevalence of miscarriage across all age groups ranges from 12% to 20%. Despite the great incidence of miscarriage, public awareness and understanding about pregnancy loss remain inadequate. Currently, social media platforms, such as Instagram, are frequently utilised by the public as a mechanism to address their health-related concerns.</div></div><div><h3>Objective</h3><div>This study aims to determine the characteristics of content disseminated on Instagram regarding International Pregnancy Loss/Miscarriage Day over the preceding three-year period.</div></div><div><h3>Study Design</h3><div>This was an analytical-observational study to describe community participation on Instagram in commemorating International Pregnancy Loss Day 2022-2024. Hashtags used include #pregnancyloss, #pregnancylossawareness, and #pregnancylossjourney. Data were analysed using content analysis and simple nominal descriptive statistics to enable comparison.</div></div><div><h3>Results</h3><div>A total of 600 Instagram posts were deemed eligible and met the specified inclusion criteria for subsequent analysis. The data revealed that the predominant form of content consists of text/quotes, comprising 44.38% (n=248) of the total content. The most common content type was personal experience sharing, accounting for 55.6% (n=334), followed by education/information for 44.24% (n=265).</div></div><div><h3>Conclusion</h3><div>The utilization of social media platforms like Instagram to commemorate International Pregnancy Loss Day, particularly by health care provider, has huge potential benefit to spread awareness, information, as well as providing support for patients.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100487"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare professionals’ experiences of discussing sexual function with menopausal women using a vaginal pessary","authors":"Monica Quinlan BSc, MSc,&nbsp;Victor Olagundoye MBBS, MMedSci, MSc, MRCOG","doi":"10.1016/j.xagr.2025.100485","DOIUrl":"10.1016/j.xagr.2025.100485","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>Pelvic organ prolapse is a common condition with high prevalence among postmenopausal women, many of whom are sexually active. A vaginal pessary is an effective, nonsurgical treatment alternative for well-selected, motivated patients and those unfit for surgical management. Open discussion on sexual function is a crucial part of counseling in these women to ensure that they are fitted with the most appropriate pessary and minimize complications.</div></div><div><h3>OBJECTIVE</h3><div>This study aimed to explore healthcare professionals’ experiences of discussing sexual function with postmenopausal women with pelvic organ prolapse receiving vaginal pessary management in a urogynecology clinic.</div></div><div><h3>STUDY DESIGN</h3><div>Semistructured, in-depth qualitative interviews were conducted in a tertiary university teaching hospital in England with an established urogynecology department. The sample comprised 10 volunteers (7 female and 3 male, consisting of 3 consultants, 1 advanced nurse practitioner, 2 clinical nurse specialists, and 4 specialist registrars). All volunteers were experienced in managing women with prolapse, including inserting and removing vaginal pessaries and discussing sexual intercourse and intimacy.</div></div><div><h3>RESULTS</h3><div>Postmenopausal women were found to be reluctant and embarrassed to engage in open discussion on sexual intimacy, which can be improved by building trust. Being seen by female healthcare professionals, having a female chaperone, and using appropriate interpreters (in cases of language barriers) significantly improved women's willingness to discuss sexual issues.</div></div><div><h3>CONCLUSION</h3><div>The study demonstrated that postmenopausal women found it difficult and were hesitant and embarrassed to openly discuss sexual issues, which is important in choosing the most suitable vaginal pessary. This problem can be alleviated by building trust between healthcare professionals and patients, by healthcare professionals remaining sensitive to patients’ ethnic and cultural backgrounds, and by respecting women's choice of healthcare professional.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100485"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143856109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to Effects of the sampling time on the vaginal microbiota in healthy pregnant women: a prospective observational study’ [AJOG Global Reports Volume 5, Issue 1, February 2025, 100460]","authors":"Hiroshi Mori MD ,&nbsp;Eiji Shibata PhD ,&nbsp;Emi Kondo MD ,&nbsp;Mitsumasa Saito PhD ,&nbsp;Kiyoshi Yoshino PhD ,&nbsp;Kazumasa Fukuda PhD","doi":"10.1016/j.xagr.2025.100483","DOIUrl":"10.1016/j.xagr.2025.100483","url":null,"abstract":"","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100483"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with a positive Tilburg Pregnancy Distress Scale among hospitalized Ghanaian obstetric patients","authors":"Dhanalakshmi Thiyagarajan MD, MPH ,&nbsp;Astrid Sarfo BS ,&nbsp;Alim Swarray-Deen MBChB, MS ,&nbsp;Sarah Compton PhD, MPH ,&nbsp;Emma Lawrence MD, MS ,&nbsp;Promise Sefogah MBChB, MPH","doi":"10.1016/j.xagr.2025.100486","DOIUrl":"10.1016/j.xagr.2025.100486","url":null,"abstract":"<div><h3>Background</h3><div>Psychological distress during the antenatal and postpartum period can negatively impact the quality of life and health of the pregnant person and fetus(es). But there is a discrepancy between Ghanaian community prevalence and engagement with mental health services leading to underdiagnosis and missed therapeutic opportunities. Therefore, it is important to identify factors that contribute to the gap of underdiagnosis and treatment, and screening for pregnancy distress is the first step in bridging this gap.</div></div><div><h3>Objective</h3><div>To identify factors associated with increased prenatal and postpartum pregnancy distress via the administration of the Tilburg Pregnancy Distress Scale (TPDS).</div></div><div><h3>Study Design</h3><div>We performed a cross-sectional study of obstetric patients who were admitted at the largest referral teaching hospital in urban Ghana between November 20, 2023, and December 22, 2023. Patients were eligible to participate if they were admitted to the 275-bed maternity block for an antepartum or postpartum indication, alert and oriented, and able to speak one of the following languages: English, Twi, or Ga. Patients below the age of 18 years, or critically ill or unstable were excluded. Participants were asked about their socioeconomics, medical history, current pregnancy and/or delivery outcomes, and satisfaction with care. All patients then completed the validated TPDS, a multiple-choice questionnaire to determine the level of pregnancy or postpartum-related distress.</div></div><div><h3>Results</h3><div>Among hospitalized obstetric patients in Ghana, less than 1% reported a diagnosed depression, anxiety, or mental health disorder. However, over 37% of our participants, both antepartum and postpartum, screened positive for pregnancy distress using the TPDS. Among antepartum participants, young age, low household income, and low parity were significantly associated with a positive pregnancy distress screen. Among postpartum participants, no factors were significantly associated with a positive screen in the final, controlled, model.</div></div><div><h3>Conclusion</h3><div>Our study is the first to identify factors associated with Ghanaian patients’ pregnancy distress, which can contribute to pregnancy, maternal, and child health consequences. Over one-third of obstetric patients screened positive on the TPDS with prevalence rates comparable across antepartum and postpartum patients. Our study identified antepartum patient factors of young age, low income, and low parity for increased positive screening on the TPDS. Identifying Ghanaian pregnant patients with these factors may help to target those at the greatest need for increased screening and monitoring, which is aligned with the Sustainable Development Goals.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100486"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personal experience with abortion: a determining factor in Physician's attitudes towards abortion","authors":"Reagan M. Ingoma MD, MPH ,&nbsp;So Yoon Kim ,&nbsp;Erick N. Kamangu PhD","doi":"10.1016/j.xagr.2025.100478","DOIUrl":"10.1016/j.xagr.2025.100478","url":null,"abstract":"<div><h3>Background</h3><div>The increase in illegal abortions raises concerns about the role of physicians in providing safe abortion care. Understanding physicians' views in multicultural countries like the DRC is essential, even though the Maputo Protocol permits safe abortion care. The research aims to determine the impact of their experience with abortion on their attitudes towards abortion.</div></div><div><h3>Method</h3><div>This is cross-sectional study involving 265 physicians from The Democratic Republic of Congo, conducted between April 1st and June 30th, 2024, using a convenience sampling technique that determines doctors' attitudes toward abortion to lay the groundwork and pave the way for future research on this issue. The study used a chi-square test to analyze categorical variables, Spearman correlation with 2 hypotheses, and multinomial logistic regression to predict the connection between the explanatory, the confounding variables, and the physician attitudes towards abortion.</div></div><div><h3>Results</h3><div>On a scale of 1−5, the median score was 3, the mean was 2.95, and the standard deviation was 0.661. We found a significant correlation between physicians' personal experiences with abortion and their attitudes toward the practice (r_s 0.211, <em>P</em>.001). Doctors who have personally experienced abortion are more likely to support abortion rights than pro-life doctors (OR: 6.52, <em>P</em>.005).</div></div><div><h3>Conclusion</h3><div>Targeted training programs for healthcare providers on the medical, legal, and ethical aspects of abortion care are crucial for equipping them with essential knowledge and skills. Public health initiatives should create and share standardized protocols for abortion care to ensure consistent quality across all healthcare facilities, especially in rural and underserved areas, promoting equitable access to such services.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100478"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of unacceptable bleeding in long-term users of 52-mg levonorgestrel intrauterine device: a prospective observational study","authors":"Patty A.H.H. van der Heijden MD,&nbsp;Karlijn A. Röttgering,&nbsp;Tamara J. Oderkerk MD,&nbsp;Jeanne P. Dieleman,&nbsp;Arianne C. Lim PhD,&nbsp;Marlies Y. Bongers PhD,&nbsp;Peggy M.A.J. Geomini PhD","doi":"10.1016/j.xagr.2025.100474","DOIUrl":"10.1016/j.xagr.2025.100474","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>In the first month after the insertion of the 52-mg levonorgestrel intrauterine device, irregular vaginal bleeding often occurs. In 6% to 18% of 52-mg levonorgestrel intrauterine device users, irregular vaginal bleeding reoccurs or continues for more than 6 months after insertion of the device. This study hypothesized that the addition of estradiol may be beneficial for the regeneration of the endometrium and may consequently decrease irregular bleeding, as these basal vessels might be shielded by the regenerated endometrium.</div></div><div><h3>OBJECTIVE</h3><div>This prospective observational study aimed to evaluate the effectiveness of estradiol in treating irregular bleeding in patients who have had a 52-mg levonorgestrel intrauterine device in place for at least 6 months.</div></div><div><h3>STUDY DESIGN</h3><div>The study was conducted in 2 hospitals and in 1 general practice in the Netherlands. Patients with a 52-mg levonorgestrel intrauterine device who experienced irregular bleeding and who chose to undergo estradiol treatment were included. Treatment consisted of 2 mg of oral estradiol daily for 6 weeks. The primary outcome was the number of bleeding days a month after 3 months of estradiol treatment compared with baseline. The secondary outcomes included the number of bleeding days 12 months after the start of medication, bleeding patterns, discontinuation rate of the 52-mg levonorgestrel intrauterine device, side effects, adverse events, and patient satisfaction at 3 and 12 months of follow-up.</div></div><div><h3>RESULTS</h3><div>A total of 39 patients provided informed consent and completed the baseline questionnaires. The mean number of bleeding days decreased significantly from 22.5 days per month at baseline to 12.8 days per month 3 months after starting estradiol treatment. The 52-mg levonorgestrel intrauterine device was removed in 10.3% of patients at 3 months of follow-up and 33.3% of patients at 12 months of follow-up. The number of women reporting acceptable bleeding patterns and satisfaction with the 52-mg levonorgestrel intrauterine device increased substantially over 12 months of follow-up.</div></div><div><h3>CONCLUSION</h3><div>A decrease in the number of bleeding days was observed in long-term 52-mg levonorgestrel intrauterine device users who experienced unfavorable bleeding after the administration of estradiol for 6 weeks. In addition, satisfaction rates increased significantly.</div></div><div><h3>Clinical trial registration number</h3><div>NL8007</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100474"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian rhythm disruption and polycystic ovary syndrome: a systematic review and meta-analysis","authors":"Tara Heydari MS,&nbsp;Prakash V.A.K. Ramdass MD, MPH","doi":"10.1016/j.xagr.2025.100479","DOIUrl":"10.1016/j.xagr.2025.100479","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of our systematic review and meta-analysis was to determine if circadian rhythm disruption (CRD) is associated with polycystic ovary syndrome (PCOS). Our objective was to pool the overall mean differences in biomarkers of CRD (including melatonin levels, morning and evening cortisol levels, and sleep efficiency) between PCOS patients and controls. We hypothesized that CRD will be more prominent in patients with PCOS.</div></div><div><h3>Data sources</h3><div>A systematic search of PubMed, Scopus, Embase, ClinicalTrials.Gov, and the Cochrane Database of Systematic Reviews was conducted from inception until 2024 using the following MeSH terms “circadian rhythm” OR “sleep disturbance” OR “melatonin” AND “polycystic ovary syndrome.” Citation search supplemented the systematic database search.</div></div><div><h3>Study eligibility criteria</h3><div>Inclusion criteria were women with PCOS, original case-control, cross-sectional, and cohort studies that identify parameters of CRD (melatonin, cortisol, and sleep disturbance). Exclusion criteria were women with endocrine and metabolic co-morbidities, menopausal women, case reports, review studies, animal studies, abstracts, and conference presentations. There was no time restriction for year of publication.</div></div><div><h3>Study appraisal and synthesis methods</h3><div>Two investigators (T.H. and P.R.) assessed the quality of the studies included using the Newcastle-Ottawa Scale. Forest plots were created using the Open Meta Analyst software. Publication bias was assessed in Egger's and Begg's tests.</div></div><div><h3>Results</h3><div>A total of 16 studies were included in the systematic review and 12 studies were included in the meta-analysis (N=1,100 women [531 PCOS patients and 569 controls]). Pooled analysis showed that the mean difference in melatonin levels between PCOS patients and controls was 14.294 pg/mL, 95% CI [6.895, 21.693]. The overall mean difference in morning and evening cortisol between PCOS patients and controls was 1.103 pg/mL, 95% CI [−1.058, 3.265], and 3.574 pg/mL, 95% CI [1.741, 5.407], respectively. Pooled difference in mean sleep efficiency scores between PCOS patients and controls was –4.059, 95% CI [−6.752, −1.366]. Risk of bias assessment showed that NOS scores ranged from 7 to 9.</div></div><div><h3>Conclusions</h3><div>Our meta-analysis provides evidence that circadian rhythm disruption is positively associated with polycystic ovary syndrome. This is substantiated by differences in parameters indicative of circadian rhythm disruption, including melatonin levels, evening cortisol, and sleep efficiency.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100479"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy outcomes following surgical repair of female genital fistula in Uganda","authors":"Abner P. Korn MD ,&nbsp;Justus K. Barageine PhD ,&nbsp;Hadija Nalubwama MPH ,&nbsp;Jaffer Okiring PhD ,&nbsp;Florence Nalubega MMed ,&nbsp;Shane Ian Asiimwe MMed ,&nbsp;Alphonsus Matovu MMed ,&nbsp;Alison M. El Ayadi ScD","doi":"10.1016/j.xagr.2025.100481","DOIUrl":"10.1016/j.xagr.2025.100481","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Women developing genital fistula and undergoing fistula repair in sub-Saharan Africa and South Asia are largely of reproductive age, and fistula prevalence is highest in countries with high fertility and where social values are placed on childbearing. Optimizing women's health following female genital fistula and surgical repair requires further understanding of the risks to subsequent pregnancies and how to mitigate them, to enable women to achieve their desired family size without additional morbidity.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;We sought to contribute to the postfistula repair evidence base through estimating rates of spontaneous abortion and stillbirth as well as the associated risk factors of these adverse outcomes in pregnancies following fistula repair.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;We captured data on sociodemographic characteristics, obstetric and fistula history, and pregnancy and childbirth care and experiences, and outcomes for the first postrepair pregnancy from 302 women who became pregnant within 10 years following genital fistula repair, recruited from six fistula repair facilities in Uganda. We described sociodemographic characteristics, spontaneous abortion (pregnancy loss &lt;20 weeks gestational age), and stillbirth (intrauterine fetal death at ≥20 weeks gestational age) and determined factors associated with these outcomes using logistic regression. We compared outcomes to two external data sources: a meta-analysis and propensity-score matched Ugandan women of reproductive-age.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Overall, 14% (43/302) of the participants had spontaneous abortions and 5% (12/255) had stillbirths in postrepair pregnancies. The spontaneous abortion rate in our study was higher compared to a recent meta-analysis; however, the stillbirth rate was not. The stillbirth rate in our study was 2.5 percentage-points higher compared to the general population (95% CI 0.2–4.9, &lt;em&gt;P&lt;/em&gt;=.036). Factors independently associated with increased risk of spontaneous abortion included fistula type, vaginal bleeding during pregnancy, any urine leakage, and educational attainment. Vesicovaginal fistula (VVF)-high (VVF types I and III) vs VVF-low (VVF type II Aa Ab Ba Bb) had significantly reduced odds of spontaneous abortion (adjusted odds ratios [aOR] 0.11, 95% CI 0.03–0.45, &lt;em&gt;P&lt;/em&gt;=.002) and rectovaginal fistula and VVF-other (other or not indicated) had marginally reduced odds (aOR 0.38, 95% CI 0.012–1.14, &lt;em&gt;P&lt;/em&gt;=.083 and aOR 0.26, 95% CI 0.05–1.25, &lt;em&gt;P&lt;/em&gt;=.093, respectively). In bivariate analyses, any urine leakage, assisted vaginal delivery, and emergency cesarean section were highly correlated with stillbirth. Stillbirth risk was over-10-fold higher among individuals reporting urine leakage (OR 10.5, 95% CI 2.75–20.43, &lt;em&gt;P&lt;/em&gt;=.001). Assisted vaginal birth and emergency cesarean birth were both associated with 17-fold increased odds of stillbirth (OR 16.93, 95% C","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100481"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to ’Guillain-Barré syndrome in pregnancy: a case report and review of the literature’ [AJOG Global Reports, Volume 4, Issue 4, November 2024, 100396]","authors":"Corina Iliadi-Tulbure PhD ,&nbsp;Maria Cemortan PhD ,&nbsp;Svetlana Jubirca PhD ,&nbsp;Viorica Cospormac PhD ,&nbsp;Cristina Bubulici ,&nbsp;Maria-Magdalena Vicol","doi":"10.1016/j.xagr.2025.100482","DOIUrl":"10.1016/j.xagr.2025.100482","url":null,"abstract":"","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 2","pages":"Article 100482"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}